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ABSTRACT: To evaluate the trends relative to incidence of Hashimoto's thyroiditis and Graves' disease from 1935 through 1967, records of all diagnosed cases occurring in residents of Rochester, Minnesota, were identified through the facilities of the Rochester-Olmsted County epidemiologic program. During those 33 yr, 246 cases of Hashimoto's thyroiditis and 256 cases of Graves' disease were diagnosed in the subject population. The average annual incidence rates per 100,000 for Hashimoto's thyroiditis for females increased from 6.5 (1935–1944) to 21.4 (1945–1954) to 67.0 (1955–1964) to 69.0 (1965–1967). There was no indication that the incidence of Graves' disease changed in any significant or consistent pattern during the 33 yr. The average annual rate for females was 36.8/100,000/yr for all age groups; the rate was highest among women 20–39 yr old.
Metabolism.