Miguel Peñarrocha-Diago

University of Valencia, Valenza, Valencia, Spain

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Publications (66)68.83 Total impact

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    ABSTRACT: Abstract Objective: To describe the Horizontal Denture®, a new implant-supported prosthetic alternative for edentulous patients with atrophied edentulous maxillae, designed to combine the advantages of conventional removable overdentures and hybrid fixed prostheses. Two cases treated following this prosthetic approach are presented. Materials and Method: The Horizontal Denture® is an implant-supported removable horizontal slide-in prosthesis. The overdenture superstructure slides horizontally in antero-posterior direction onto an implant-supported primary structure and is retained by friction. Two patients with atrophic upper maxillae were rehabilitated following this technique. Eight implants were inserted in the first case and six in the second. Prosthetic and implant complications and patient satisfaction were analyzed over a 12-month follow-up.Results: Neither prosthetic nor implant complications were observed during the follow-up period. Patient satisfaction with the slide-in prostheses was very high. Conclusions: The Horizontal Denture® prosthetic design was described and two patients were rehabilitated. This technique allowed, like conventional overdentures, camouflage of the fixing screw access holes and a good hygiene, while providing a biomechanical behavior equivalent to a fixed prosthesis. Both patients were highly satisfied with the treatment.
    Journal of Oral Implantology 01/2014; · 1.15 Impact Factor
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    ABSTRACT: The purpose of this study was to compare the clinical efficacy of articaine at 4% (epinephrine 1:100,000) with bupivacaine at 0.5% (epinephrine 1:200,000) for surgical extraction of impacted mandibular third molars. This was a randomized, double blind, split-mouth, clinical trial. Thirty-six patients took part and underwent extraction of 72 lower third molars. The variables studied were: anesthetic latency time, intra-operative bleeding, anesthetic quality, hemodynamic changes during the surgical intervention, anesthetic duration in the soft tissues, post-operative analgesia and post-operative pain at 2, 6, 12 and 24 hours using a visual analogue scale, as well as any need for additional rescue medication. Latency time was 2.0 minutes for articaine and 3.1 minutes for bupivacaine, with statistically significant difference (p<0.05). Bleeding was greater when bupivacaine was used (p<0.05) and anesthetic quality was greater with articaine (p<0.05). The duration of soft tissue anesthesia was longer with bupivacaine (p<0.05). Differences in post-operative analgesia, haemodynamic changes, post-operative pain and the quantity of rescue medication consumed were not statistically significant (p>0.05). Articaine showed greater clinical efficacy than bupivacaine, reducing latency time, bleeding, anesthetic duration in the soft tissues and achieving higher anesthetic quality, requiring less reinforcement during surgery than bupivacaine. Key words:Articaine, bupivacaine, anesthetic efficacy, impacted mandibular third molar.
    Journal of clinical and experimental dentistry. 04/2013; 5(2):e66-71.
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    ABSTRACT: PURPOSE:: To review morphometric studies performed in animals assessing the dynamics of the buccal bone crest after immediate implant placement and ridge preservation techniques. MATERIAL AND METHOD:: A bibliographic search in PubMed was performed. Studies that analyzed morphometrically in animals the buccal bone crest dynamics after immediate implant placement or ridge preservation techniques were included. Twenty-five studies met the inclusion criteria. RESULTS:: Immediate implant placement does not prevent the resorption of the buccal bone crest. To minimize this resorption, 2 mm width of the buccal bone crest, palatal/lingual implant placement, and an adequate implant diameter for the width of the ridge are required. The regeneration of the gap after immediate implant placement limits the resorption of the buccal bone crest. Flap elevation and implant surface showed no relation with this resorption. Ridge preservation techniques associated with mucogingival surgery minimize buccal bone crest resorption. Biomaterials are more effective than autograft. CONCLUSIONS:: Immediate implant placement does not prevent the resorption of the buccal bone crest after dental extraction. Ridge preservation techniques minimize this resorption.
    Implant dentistry 03/2013; · 1.51 Impact Factor
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    ABSTRACT: Purpose: To report 20 cases with implant periapical pathology diagnosed during the osseointegration phase, evaluating retrospectively the efficacy of the treatment with implant periapical surgery. Materials and Methods: A retrospective chart review was conducted of all patients in whom implant periapical surgery was performed between 1996 and 2010. The criteria for diagnosing implant periapical pathology and, accordingly, performing implant periapical surgery were: (1) acute pain during the osseointegration period (8 weeks after implant placement) located in the area of the affected implant or presence of mucous fistula in relation with the implant apex; (2) absence of implant mobility; (3) non-dull percussion of nonsubmerged implants; and (4) presence or absence of implant periapical radiolucency. Results: Twenty-two implants were diagnosed with periapical pathology in 20 patients (13 women and 7 men) with a mean age of 54.3 years (range, 32 to 70 years) and were consecutively treated by a surgical approach. In 19 implants, the diagnosis was acute apical peri-implantitis (nonsuppurated in 7 cases and suppurated in 12), as based on the symptoms and radiographic sign, and in 3 cases it was subacute apical peri-implantitis, as based on the presence of a fistula. After a minimum follow-up of 1 year, 20 implants remained functional, with no clinical or radiologic alterations; the survival rate of the treated implants was 91%. Conclusion: The early diagnosis of inflammatory implant periapical lesions during the osseintegration phase, and their prompt surgical treatment, led to a survival rate of the treated implants of 91%.
    The International journal of oral & maxillofacial implants 01/2013; 28(1):158-62. · 1.91 Impact Factor
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    ABSTRACT: PURPOSE: To present a case series of 5 patients with oral teratomas, discussing the treatment and follow-up. REPORT OF CASES: Five patients (4 girls and 1 boy) with oral teratomas presented at the Maxillofacial Surgery Department of a University Hospital with a reference population of 1,000,000 between 1980 and 2002. The associated lesions, clinical examination, histopathology, treatment and follow-up were registered and described. The newborns presented associated congenital malformations such as cleft palate, bifid tongue, dorso-nasal fistula and nasal dermoid cyst. In all 5 cases the tumor mass was excised at its base with surrounding normal tissue under general anesthesia combining conventional and electric scalpels. Histological analysis resulted in different compositions of multiple tissues typical of teratomas. After a mean follow-up of 8 years no sign of tumor recurrence had been detected. CONCLUSION: Teratomas were a rare finding within a large population of newborn patients. Five tumors were excised and histologically diagnosed as teratomas. No recurrence occurred after 8 years of follow-up.
    Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 08/2012; · 1.58 Impact Factor
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    ABSTRACT: The purpose of this study was to compare marginal bone loss and success rates 1 year after implants had been placed in maxillary molar sites, either immediately postextraction or after the extraction sites had healed (delayed). A retrospective case study was made of subjects treated with immediate or delayed dental implants in the maxillary molar region between January 2006 and December 2008. A protocol was prepared in which patient age, sex, implant length and diameter, type of prosthesis, buccal plate width, and use of bone grafting were recorded. After 12 months, data relating to the clinical and radiologic conditions of the implants and the success rate according to the criteria of Buser et al were recorded. The variables were analyzed statistically (Student t test, Pearson correlation, Games-Howell test). The study included 123 implants placed in 70 patients; 35 implants were immediate and 88 were delayed. Two immediate and six delayed implants failed, resulting in success rates of 94.3% and 93.2%, respectively. Average marginal bone loss was 0.56 mm for immediate implants and 0.67 mm for delayed implants. The placement of immediate implants in maxillary molar sites achieved similar results to implants placed in healed sites in the same region after 12 months. No statistically significant differences were found between implant survival rates or average marginal bone loss.
    The International journal of oral & maxillofacial implants 05/2012; 27(3):604-10. · 1.91 Impact Factor
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    ABSTRACT: The aim of this study was to compare the survival of implants placed in mature bone with the survival of implants placed in fresh extraction sockets in the same patients. A retrospective study of patients treated simultaneously with at least one immediate and one nonimmediate implant was carried out for the period 2005 to 2008. Data were recorded for patient age and sex; implant length, diameter, and position; and, for postextraction implants, distance between the implant and the alveolar bone. One thousand twenty-two implants were placed in 150 patients; 480 were placed immediately and 542 were placed in mature bone. The mean implant survival rate was 93.4%; survival rates were 93.8% for immediate implants and 93.2% for nonimmediate implants. The failure rate in the maxilla was 5.2% and in the mandible it was 2.8%. The failure rate for immediate implants in the posterior maxilla was 8.5%, which was statistically significantly higher than for implants placed elsewhere. Of the failed implants, 72% were early failures. The survival rate of implants placed in fresh extraction sockets was similar to that of implants placed in mature bone. A statistically significantly higher failure rate was seen with immediate implants placed in the posterior maxilla.
    The International journal of oral & maxillofacial implants 03/2012; 27(2):421-7. · 1.91 Impact Factor
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    ABSTRACT: To assess pain and swelling in the first 7 days after periapical surgery and their relationship with the agent used for bleeding control. A prospective study was conducted between October 2006 and March 2009. Patients subjected to root surgery, who completed the questionnaire and who consented to the postoperative instructions were included in the study. The subjects were divided into two groups according to the hemostatic agent used: A) gauze impregnated with anesthetic solution with vasoconstrictor; or B) aluminum chloride. The patients were administered a questionnaire, and were asked to record the severity of their pain and swelling on a plain horizontal visual analog scale (VAS). Data were recorded by the patients on the first 7 postoperative days. In addition, the patients were asked to record analgesic consumption. A total of 76 questionnaires (34 in group A and 42 in group B) were taken to be correctly completed. Pain was reported to be most intense two hours after surgery. At this point 52.6% of the patients had no pain. Seventy-five percent of the patients consumed analgesics in the first 24 hours. There were no significant differences between the two groups in terms of the intensity of pain or in the consumption of analgesics. Swelling reached its maximum peak on the second day; at this point, 60.6% of the patients suffered mild or moderate swelling. The Expasyl group showed significantly greater swelling than the gauzes group. The type of hemostatic agent used did not influence either the degree of pain or the need for analgesia among the patients in this study. However, the patients belonging to the Expasyl group suffered greater swelling than the patients treated with gauzes impregnated with anesthetic solution with vasoconstrictor.
    Medicina oral, patologia oral y cirugia bucal 02/2012; 17(4):e594-600. · 1.02 Impact Factor
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    ABSTRACT: To describe the rehabilitation with implants placed simultaneously with particulated bone graft in 4 patients diagnosed with recessive dystrophic epidermolysis bullosa. A retrospective study was conducted of 4 patients diagnosed with recessive dystrophic epidermolysis bullosa and treated with dental implants and simultaneous particulate bone graft from January 2005 to December 2009. All patients had marked oral involvement, with devastating alterations in the soft and hard tissues and were rehabilitated with a fixed prosthesis. Eighteen implants showed dehiscence or fenestration and were placed simultaneously with particulated bone grafts to cover exposed threads: 14 received autologous bone and 4 tricalcium betaphosphate. In 16, the bone graft was covered with resorbable collagen membranes and in 2 with a nonresorbable titanium-reinforced membrane. Of the 18 implants, 8 were placed in the maxilla combining drills and osteotomes and 10 in the mandible with the conventional drilling procedure. All implants survived after a minimum follow-up of 12 months (range 12 to 48). The results of this small-sample clinical study suggest that endosseous implants can be placed simultaneously with particulated bone graft, providing support for a fixed prosthesis in patients with recessive dystrophic epidermolysis bullosa and considerably improving these patients' quality of life.
    Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 01/2012; 70(1):e51-7. · 1.58 Impact Factor
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    ABSTRACT: The present study investigates sinus membrane rupture in direct maxillary sinus lift with the rotary technique and with ultrasound, examining the survival of implants placed after sinus augmentation, and analyzing the bone gain obtained after the operation and 12 months after placement of the prosthetic restoration. A retrospective study was made of 45 patients requiring maxillary sinus lift or augmentation for implant-prosthetic rehabilitation. Use was made of the handpiece and ostectomy drills for the rotary technique, and of specific tips for ultrasound. The implant success criteria were based on those developed by Buser. The bone gain obtained as a result of sinus lift was calculated from the postoperative panoramic X-rays. A total of 57 direct elevations of the maxillary sinus were carried out: 32 with the rotary technique and 25 with ultrasound. Perforations of Schneider's membrane with the rotary technique and ultrasound occurred in 7% and 1.7% of the cases, respectively, with membrane integrity being preserved in 91.2%. Of the 100 implants placed, 5 failed after one year of follow-up in the rotary technique group, while one implant failed in the ultrasound group. The rotary technique in turn afforded a bone gain of 5.9 mm, versus 6.7 mm with ultrasound. Perforations of the membrane sinusal in direct lift were more frequent with the rotary technique (7%) than with ultrasound (1.7%). Implant survival and bone gain were both greater when ultrasound was used.
    Medicina oral, patologia oral y cirugia bucal 12/2011; 17(3):e457-61. · 1.02 Impact Factor
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    ABSTRACT: A description is made of transcrestal sinus lift using the sinus balloon technique, evaluating the bone height achieved and implant success one year after prosthetic loading. Between January and July 2007, transcrestal sinus lift using the sinus balloon technique for dental implant placement was carried out in 6 patients. A panoramic X-ray study and maxillary computed tomography scan were carried out before the operation, in order to discard possible sinus pathology. During the intervention, the integrity of the sinus membrane was evaluated using a Medi Pack Pal endoscope (Farol Store and Co., Tuttlingen, Germany), and the intraoperative complications were analyzed. The dental implants were placed in the same surgical step in the presence of 3 mm or more of residual bone. Following the operation, panoramic X-rays were used to assess the bone height gained. One year after prosthetic loading, the implant success rate was determined based on the criteria of Buser. One patient was excluded due to Schneider's membrane perforation as confirmed by endoscopy. Transcrestal sinus lift was carried out in 5 males with a mean age of 41.6 years (range 27-51), without antecedents of sinus disease. There were no intraoperative complications. In four patients the implants were placed simultaneous to sinus lift, while in another case implant placement was postponed due to insufficient remaining bone height. The mean gain in height after the operation was 8.7 mm. One year after prosthetic loading, the implant success rate was 100%. Transcrestal sinus lift using the sinus balloon technique is a minimally invasive procedure. In 5 patients the bone height gained proved sufficient to allow implant placement even in the presence of 3 mm of residual bone.
    Medicina oral, patologia oral y cirugia bucal 12/2011; 17(1):e122-8. · 1.02 Impact Factor
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    ABSTRACT: A study is made of the clinical course of patients with episodic cluster headache following the injection of corticosteroids in the proximity of the sphenopalatine ganglion of the affected side. A retrospective observation study was made corresponding to the period between 2006 and 2010. Patients with episodic cluster headache received corticosteroid infiltrations in the vicinity of the sphenopalatine ganglion. Data were collected to assess the clinical course, quantifying pain intensity and quality of life. A total of 23 patients (11 women and 12 men) with a mean age of 50.4 years (range 25-65) were included. Forty percent of the patients had undergone dental extractions in the quadrant affected by the pain, before the development of episodic cluster headache, and 37.8% underwent extractions in the same quadrant after appearance of the headache. Most of the patients suffered 1-3 attacks a day, with a duration of pain of between 31-90 minutes. The mean pain intensity score during the attacks at the time of the first visit was 8.8 (range 6-10), versus 5.4 (range 3-9) one week after the first corticosteroid injection. On the first visit, 86.9% of the patients reported unbearable pain, versus 21.7% after one week, and a single patient after one month. The evolution of episodic cluster headache is unpredictable and variable, though corticosteroid administration clearly reduces the attacks and their duration.
    Medicina oral, patologia oral y cirugia bucal 12/2011; 17(3):e477-82. · 1.02 Impact Factor
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    ABSTRACT: The aim of this study was to describe the rehabilitation of patients diagnosed with recessive dystrophic epidermolysis bullosa (RDEB), with edentulous maxillas and/or mandibles, by using fixed full-arch short-expand prostheses supported by 4 anterior implants. A retrospective study was carried out to study edentulous patients with RDEB rehabilitated with fixed full-arch prostheses supported by 4 anterior implants. In total, 32 anterior implants were placed and used to support 8 full-arch fixed prostheses; 20 implants were placed in the maxilla by using osteotomes and 12 in the mandible by using conventional drilling. Implant success rate was 100% after an average follow-up of 22.9 (range 12-48) months after prosthetic loading. Patient satisfaction with the implant therapy was very high (mean 9.0) for all the factors assessed. Fixed full-arch short-expand prostheses supported by 4 anterior implants can be successfully used to rehabilitate patients with recessive dystrophic epidermolysis bullosa, considerably improving these patients' quality of life.
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 06/2011; 112(2):e4-10. · 1.50 Impact Factor
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    ABSTRACT: To determine the prevalence, location, and size of maxillary sinus septa, and to compare the results of panoramic radiographs and computed tomography (CT) scans. This study included 30 patients, 17 women and 13 men, with a mean age of 50.9 years (range, 28-73 years), undergoing treatment planning for implant-supported restorations in the maxilla. Three observers analyzed the panoramic radiographs, the conventional CT scans in acetate, and the Implametric 3-dimensional CT (3Dent, Valencia, Spain). The maxillary sinus septa of each patient and the type of septa, as well as its location and size, were recorded. In 60 maxillary sinuses, panoramic radiographs showed 32 septa (53.3%); CT in acetate showed 42 septa (70%); and Implametric 3-dimensional CT showed 40 septa (66.7%). Most septa (60%) were located in the middle region of the maxillary sinus, 22.5% in the posterior region, and 17.5% in the anterior region. The mean height of the septa was 4.78 ± 1.76 mm. Panoramic radiographs led to an erroneous diagnosis in 46.5% of the cases. Maxillary sinus septa are a frequent anatomic variation. They can be found in any of the maxillary sinus regions independently of patient edentulism. The panoramic radiograph can lead to false-positive and false-negative findings in the visualization of septa in almost half of cases. Therefore, whenever a maxillary sinus lift is planned, a thorough study of the affected sinus should be made using CT.
    Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 02/2011; 69(2):507-11. · 1.58 Impact Factor
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    ABSTRACT: The aim of the study was to examine articles published on risk factors associated with early failure of dental implants. We conducted a search on PubMed for articles published between January 2000 and December 2009 using the keywords 'dental implants' and 'early failure'. Seven studies that specified the number of early failed implants and studied the associated risk factors were included. Early failures are caused by the inability of tissue to establish osseointegration prior to prosthetic restoration; however the causal factors and mechanisms are unclear. In the reviewed literature there was a higher percentage of early than late failures; nevertheless, few articles were found that analyzed risk factors associated with early implant failure. In the majority of studies, statistically significant factors associated with early implant failure were smoking, quantity and quality of bone, and posterior implant location. The low number of studies in the literature does not allow definitive conclusions to be drawn.
    Medicina oral, patologia oral y cirugia bucal 01/2011; 16(4):e514-7. · 1.02 Impact Factor
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    ABSTRACT: To present the largest series of orofacial lymphangioma in children published to date, analyzing the clinical characteristics and evolution of, and the treatment used for, these lesions. The clinical data from patients diagnosed with orofacial lymphangioma, who were treated from 1998 to 2008 at the Oral and Maxillofacial Surgery Unit, Children's Hospital La Fe of Valencia (age 0 to 14 years), were reviewed. All patients with a clinical, radiographic, or, in surgical cases, histopathologic, diagnosis of orofacial lymphangioma were included. A total of 14 patients (8 boys and 6 girls; mean age 4.6 years) were included in the present study. Of the 14 cases, 9 had been diagnosed before the patients were 2 years old and 2 of which were congenital; 8 cases were located on the dorsum of the tongue. The lesion diameter was 1 to 2 cm in 9 patients, with 1 less than 1 cm, and was larger than 2 cm in 5. For treatment, 4 lymphangiomas were monitored periodically and resolved spontaneously, 1 was treated with sclerotherapy, and 9 with surgical extirpation. After surgery, 2 patients developed a recurrence within 13 months. Most of the lymphangiomas diagnosed in children occurred before 2 years of age, were on the dorsum of the tongue, and had a mean size of 1 to 2 cm. Of those treated with surgical extirpation, 2 recurred.
    Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 01/2011; 69(6):e96-9. · 1.58 Impact Factor
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    ABSTRACT: To compare the success rates, after 1 year of loading, for implants placed immediately after tooth extraction and in healed sites in patients undergoing extraction of all residual teeth for rehabilitation with a fixed, full-arch, implant-supported prosthesis. A retrospective case series study was conducted of 38 patients treated from June 2004 to June 2008 by extraction of all remaining teeth and implant placement in both mature bone and at the extraction site in the same procedure. After osteointegration, the implants were restored with fixed full-arch prostheses. The marginal bone loss around the implants was measured after 1 year. The success rate according to Buser criteria was calculated for the immediate and nonimmediate implants. A total of 41 arches were restored in 30 patients, 23 in the maxilla and 18 in the mandible. A total of 292 implants were placed, 173 immediately and 119 in mature bone. Of the 292 implants, 8 failed, 4 in the immediate group and 4 in the nonimmediate group. The mean bone loss was 0.6 mm at 1 year of loading (0.63 ± 0.18 mm at the immediate implant sites and 0.58 ± 0.26 in mature bone). The mean success rate was 96.9% overall, 97.7% for the immediate group, and 96.3% for the nonimmediate group. Enhanced bone healing and remodeling can take place in fresh extraction socket defects associated with immediately placed implants. The results of the present study have demonstrated that immediate implant osseointegration can be as, or more, successful than nonimmediate implantation during the same healing period.
    Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 11/2010; 69(1):154-9. · 1.58 Impact Factor
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    ABSTRACT: The present study was undertaken to evaluate mucoceles in the oral cavity of pediatric patients, including the clinical characteristics, treatment, and progress of the lesions. A retrospective study was performed from the medical records of patients (0-14 years old) treated for oral mucoceles between 1998 and 2008 in a reference children's hospital. All subjects with mucoceles on lips, mouth, buccal mucosa, and palate were included. The following data were recorded: age, gender, history of trauma, location, size, progression, time before diagnosis, treatment, histologic type, follow-up time, and recurrence. A total of 89 patients (mean age, 6.1 years) participated in this study. There were 89 mucoceles: 4 were congenital; 79.8% were located on the lower lip; and 69% were larger than 5 mm in diameter. Average progression time was 5.7 months (range, 1-24 months). It was observed that older patients developed more mucoceles on the tongue and lips and younger patients developed more mucoceles on the buccal mucosa and palate. The lesions of 39 subjects resolved spontaneously; 50 were removed but 4 reappeared afterward. Histologically, all lesions were extravasation mucoceles. Mucoceles were more commonly located on the lower lip; 43.8% resolved spontaneously and 8% of the surgically removed mucoceles reappeared.
    Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons 10/2010; 68(10):2468-71. · 1.58 Impact Factor
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    ABSTRACT: A review of the literature is made to evaluate factors that influence probing depth and attachment level on the distal aspect of the lower second molar (L2M) following extraction of a lower third molar (L3M). The PubMed database was searched for studies published between 1997 and March 2009 using the following keywords: mandibular third molar, distal periodontal defect, distal probing depth, distal attachment level, flap design. Randomized prospective studies, with a minimum follow-up of three months for which the full text could be obtained, and that indicated the attachment level and/or probing depth on the distal surface of the L2M in both the preoperative and postoperative periods were included. In the studies obtained, flap design had no influence on distal probing depth or distal attachment level of the L2M following extraction of an L3M. Curettage of the distal radicular surface of the L2M, together with oral hygiene control by the dentist, reduced probing depth values. Various authors recommend bone regeneration techniques in patients with a distal periodontal defect prior to extraction. The placing of membranes (resorbable or nonresorbable) is not justified; however, the use of demineralized bone powder or platelet-rich plasma gel reduces the distal probing depth and attachment level of the L2M.
    Medicina oral, patologia oral y cirugia bucal 04/2010; 15(5):e755-9. · 1.02 Impact Factor
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    ABSTRACT: Probiotics have been found to be beneficial to host health. Their primary use in medicine has been for the management of intestinal tract problems. In recent years, probiotics have been used as a treatment to promote oral health. The aim of the present study was to review published studies regarding probiotics and their effects on the oral cavity. Studies reporting the anticariogenic effects of probiotics, their use in the treatment of periodontal disease, a reduced crevicular fluid volume and cytokine content, as well as their use in the treatment of halitosis and Candida albicans were identified. Studies assessing residence time of probiotics in the oral cavity were also selected for retrieval. Most authors concluded that the use of oral probiotics was associated with an improvement in oral health, including a significantly reduced level of cariogenic and periodontal pathogens and a lower crevicular fluid volume and cytokine concentration.
    Medicina oral, patologia oral y cirugia bucal 02/2010; 15(5):e677-80. · 1.02 Impact Factor