Akuodor Godwin Christian
University of Calabar, Calabar, Cross River State, Nigeria

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Publications (1)0.37 Total impact

  • Article: Antimalarial potency of the leaf extract of Aspilia africana (Pers.) C.D. Adams.
    Akuodor Godwin Christian, Amos Grace Mfon, Essien Augustine Dick, Essien David-Oku, Akpan Joseph Linus, Ezeokpo Basil Chukwuma
    [show abstract] [hide abstract]
    ABSTRACT: To investigate the antimalarial activity of ethanol extract of Aspilia africana (A. africana) leaf. The ethanol extract of A. africana leaf (100-400 mg/kg) was screened for blood schizonticidal effect against chloroquine-sensitive Plasmodium berghei (P. berghei) in mice both in early and established models of antimalarial studies. The leaf extract exhibited significant (P<0.05) antiplasmodial activity in 4-day early infection and in established infection tests with a considerable mean survival time comparable to that of standard drug, chloroquine (10 mg/kg). The findings show that ethanol extract of A. africana leaf possesses potent antiplasmodial activity which justify the use in ethnomedicine and can be developed in malaria therapy.
    Asian Pacific Journal of Tropical Medicine 02/2012; 5(2):126-9. · 0.37 Impact Factor

Institutions

  • 2012
    • University of Calabar
      • College of Medical Sciences
      Calabar, Cross River State, Nigeria
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