Publications (2)3.45 Total impact
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Article: The modification of the muscle fatty acid profile by dietary supplementation with Aspergillus awamori in broiler chickens.
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ABSTRACT: The present study was conducted to show that dietary supplementation with a fungus, Aspergillus awamori, modifies muscle fatty acid profiles in broiler chickens. A total of thirty chicks, selected from a group of 100 chicks aged 15 d, were divided into a control group and two treatment groups (ten birds per treatment). The control group was fed a basal diet, and the treatment groups were fed basal diets supplemented with A. awamori at levels of 0·05 and 0·2 %. From the start of the study at 15 d, the birds were raised for an additional 12 d, and growth and the muscle fatty acid profile were evaluated. Although feed intake was decreased by the fungus, body-weight gain and breast muscle weight were increased, and thus, feed efficiency was improved. Abdominal fat and plasma cholesterol and TAG were decreased, while plasma HDL-cholesterol and breast muscle fat content were increased. Interestingly, muscle α-tocopherol content was increased and muscle thiobarbituric acid-reactive substances were decreased by A. awamori. Furthermore, there was an observed decrease in SFA and an increase in unsaturated fatty acids in the muscle fat due to the fungus feeding. The mRNA of fatty acid synthase, acetyl-CoA carboxylase and Δ-6 desaturase in the muscle were all increased, while the mRNA of 3-hydroxyl-3-methylglutaryl-CoA reductase and carnitine palmitoyl transferase 1A were decreased by the fungus. In conclusion, the present study clearly shows that the muscle lipid profile could be modified by the addition of A. awamori to the diet.The British journal of nutrition 01/2012; · 3.45 Impact Factor -
Conference Proceeding: Effect of feeding Aspergillus Awamori on plasma lipid profile in rats given high fat die
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ABSTRACT: We have observed that feeding Aspergillus Awamori reduces abdominal fat and plasma trigryceride and cholesterol in chicken. Thus, the present study was conducted to evaluate a fungus, Aspergillus awamori so called Awamori Koji in Japan, as a probiotic to prevent lifestyle related disease. Total number of 30 rats at 5 weeks of age were divided into control and 4 treatment groups (6 rats per treatment). Positive control group was fed a commercial diet. The other 4 groups were fed purified diets containing 10% butter or 30% butter with (0.05%) or without Koji. The rats were raised for 3 weeks from 6 week of age to evaluate the effects on plasma biochemical parameters, organs weights, abdominal fat content, muscle fatty acid profile, etc. Body weight gain was increased and food intake was decreased and thus food efficiency was increased by the Koji feeding in the both butter diets. Due to the Koji feeding, abdominal fat, plasma cholesterol, triglyceride and glucose were all decreased. Furthermore, saturated fatty acids were decreased and unsaturated fatty acids were increased in the muscle. Thus, Koji (A. awamori) might be used as an effective probiotic to prevent life style related disease in mammals.The 66th Annual Meeting of Japanese Society of Nutrition and Food Science. 4 September 2011, Saga University, Japan.2011; 10/2011
