Xiaoli Ge

Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai Shi, China

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Publications (5)13.15 Total impact

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    ABSTRACT: Nonverbal pediatric patients such as infants are unable to describe their pain, which leads to the lack of a gold standard scale for their pain assessment. The aim of this study was to estimate the diagnostic performance of Face, Legs, Activity, Cry, and Consolability (FLACC) scale and Neonatal Infant Pain Scale (NIPS) for infants' pain in the absence of a gold standard. This prospective observational study recruited 202 postoperative infants, aged <12 months. Postoperative pain intensity was evaluated using FLACC and NIPS scales. The diagnostic performance of these two scales was to estimate using a Bayesian latent class model with conditional dependence. McNemar's test was applied to test whether NIPS and FLACC tests differ from each other. Under a combined model with conditional dependence, the median posterior sensitivity and specificity of the FLACC were 89.94% (95% CI: 78.48-96.83%) and 87.82% (95% CI: 78.6-95.23%), respectively. The sensitivity and specificity of the NIPS were 85.94% (95% CI: 72.15-95.6%) and 92.61% (84.05-97.52%), respectively. McNemar's test demonstrated no significant difference between FLACC and NIPS in either sensitivity or specificity. Both the FLACC and NIPS have excellent sensitivity and specificity for pain assessment in infants. The comparison test showed that the FLACC scale was no different to the NIPS scale in sensitivity and specificity. © 2015 John Wiley & Sons Ltd.
    Pediatric Anesthesia 04/2015; 25(8). DOI:10.1111/pan.12664 · 1.85 Impact Factor
  • Xiaoli Guo · Xuan Li · Xiaoli Ge · Shanbao Tong
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    ABSTRACT: This study used a S1-S2 matching paradigm to investigate the influences of visual (size) change on auditory intensity discrimination. Behavioral results showed that subjects made more errors and spent more time to discriminate change in auditory intensity when it was accompanied by an incongruent visual change, while the performance for congruent audiovisual stimuli was better especially if there is a change in auditory stimuli. Event-related potential difference waves revealed that audiovisual interactions for multimodal mismatched information processing activated the right frontal and left centro-parietal cortices around 300-400ms post S1-onset. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
    Neuroscience Letters 11/2014; 584C:241-246. DOI:10.1016/j.neulet.2014.10.043 · 2.03 Impact Factor
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    ABSTRACT: The purpose of the present study was to develop and evaluate a risk score to predict people at high risk of cardiovascular autonomic dysfunction neuropathy (CAN) in Chinese population. A population-based sample of 2,092 individuals aged 30-80 years, without previously diagnosed CAN, was surveyed between 2011 and 2012. All participants underwent short-term HRV test. The risk score was derived from an exploratory set. The risk score was developed by stepwise backward multiple logistic regression. The coefficients from this model were transformed into components of a CAN score. This score was tested in a validation and entire sample. The final risk score included age, body mass index, hypertension, resting hear rate, items independently and significantly (P<0.05) associated with the presence of previously undiagnosed CAN. The area under the receiver operating curve was 0.726 (95% CI 0.686-0.766) for exploratory set, 0.784 (95% CI 0.749-0.818) for validation set, and 0.756 (95% CI 0.729-0.782) for entire sample. In validation set, at optimal cutoff score of 5 of 10, the risk score system has the sensitivity, specificity, and percentage that needed subsequent testing were 69, 78, and 30%, respectively. We developed a CAN risk score system based on a set of variables not requiring laboratory tests. The score system is simple fast, inexpensive, noninvasive, and reliable tool that can be applied to early intervention to delay or prevent the disease in China.
    PLoS ONE 03/2014; 9(3):e89623. DOI:10.1371/journal.pone.0089623 · 3.23 Impact Factor
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    ABSTRACT: Background Central venous access (CVA) is widely used. However, its thrombotic, stenotic and infectious complications can be life-threatening and involve high-cost therapy. Research revealed that the risk of catheter-related complications varied according to the site of CVA. It would be helpful to find the preferred site of insertion to minimize the risk of catheter-related complications. This review was originally published in 2007 and was updated in 2011. Objectives 1. Our primary objective was to establish whether the jugular, subclavian or femoral CVA routes resulted in a lower incidence of venous thrombosis, venous stenosis or infections related to CVA devices in adult patients. 2. Our secondary objective was to assess whether the jugular, subclavian or femoral CVA routes influenced the incidence of catheterrelated mechanical complications in adult patients; and the reasons why patients left the studies early. Search methods We searched CENTRAL (The Cochrane Library 2011, Issue 9),MEDLINE, CINAHL, EMBASE (frominception to September 2011), four Chinese databases (CBM, WANFANG DATA, CAJD, VIP Database) (from inception to November 2011), Google Scholar and bibliographies of published reviews. The original search was performed in December 2006. We also contacted researchers in the field. There were no language restrictions. Selection criteria We included randomized controlled trials comparing central venous catheter insertion routes. Data collection and analysis Three authors assessed potentially relevant studies independently. We resolved disagreements by discussion. Dichotomous data on catheter-related complications were analysed. We calculated relative risks (RR) and their 95% confidence intervals (CI) based on a random-effects model.
    Cochrane database of systematic reviews (Online) 03/2012; 3(3):CD004084. DOI:10.1002/14651858.CD004084.pub3 · 6.03 Impact Factor
  • Xuan Li · Xiaoli Ge · Junfeng Sun · Shanbao Tong
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    ABSTRACT: Audiovisual interaction has been one of the most important topics in cognitive neurosciences. Visual stimuli could significantly impact the auditory perception, and vice versa. Nevertheless, how much the change in visual stimuli would influence the perception of auditory change remains to be investigated. In this paper, we designed an audiovisual experiment in which subjects were required to judge whether there is a change in the intensities of two sounds with 150 ms interval, while there are two simultaneously presented size-changed visual stimuli. Behavioral results demonstrated that incongruent audiovisual change could result in the illusory perception of the change in sound intensity. For the correctly judged trials, source analysis showed two characteristic windows post the first auditory stimulus, i.e., (i) the 160-200 ms window including the auditory P200 and visual N100 wave, which was related to audiovisual interaction and working memory of the first stimulus with localized sources in insula and agranular retrolimbic area; and (ii) the 300-400 ms window for P300 with sources in premotor cortex and caudate nucleus, which were related to later audiovisual interaction, change discrimination and working memory. These preliminary results implied two stages in the audiovisual change perception task, with the involvement of insula, agranular retrolimbic, premotor cortex and caudate nucleus.
    Conference proceedings: ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 08/2011; 2011:3067-70. DOI:10.1109/IEMBS.2011.6090838