Sushma Mehkri

Guru Nanak Dev Dental College & Research Institute, Sunām, Punjab, India

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Publications (4)1.15 Total impact

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    ABSTRACT: Multifocal odontogenic lesions are uncommon and have only been observed in conditions associated with known genetic mutations. To the best of our knowledge, only two cases of multifocal adenomatoid odontogenic tumours (AOT) have previously been reported in the literature. In this study, we report the first case of a bilateral, separate AOT in the maxilla in the midline in a 2-year-old female. The patient presented with bilateral expansile masses in the maxilla on either side of the midline which had been present for 6 months. She was asymptomatic and had occasional difficulty in breathing. The tumour was diagnosed as AOT and was surgically enucleated along with the associated teeth. The patient recovered well and has been on recall for 5 years. The follow-up panoramic radiograph made a fortnight ago revealed evidence of three new radio-opaque lesions with an associated tooth in the region of the anterior mandible, the premolar region of the right maxilla and the molar region of the left maxilla. To acquire additional information about AOT, all reports regarding AOT cited in 'PubMed' from 1995 onward were reviewed and the incidence, clinical features, radiographic features and management of AOT are discussed in this study.
    Dentomaxillofacial Radiology 01/2012; 41(4):342-8. · 1.15 Impact Factor
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    ABSTRACT: The aim of this study was to determine whether variations in the mesiodistal dimensions of mandibular canines had any role in sex determination. The study comprised of patients in the 19‒24-year age group (20 males and 20 females). Mesiodistal dimensions of mandibular canines was measured at the maximum mesiodistal width, first intraorally, then on plaster models of the same patient, followed by intraoral periapical radiograph of the same patient. The values were subjected to statistical analysis using t-test. It might be concluded from the results that there exists a definite statistically significant difference in the mesi-odistal width of mandibular canines when measured for males and females. Moreover, the left mandibular canine showed a greater sexual dimorphism (9.7%) when compared to the right mandibular canine (7.4%). The present study establishes a statistically significant sexual dimorphism in mandibular canines. It can be concluded that the standard mandibular canine index is a quick and easy method for determining sex and in identification of an unknown individual.
    Journal of Dental Research, Dental Clinics, Dental Prospects 01/2011; 5(2):51-4.
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    ABSTRACT: Florid Cemento-Osseous Dysplasia (FCOD) is a well recognized fibro-osseous disease of the jaws commonly seen in the middle aged African women, although it may occur in the Caucasians and Asians. There is a reported inci- dence of less than 2% in the Indian population. The clinical and the radiographic features of FCOD may overlap with features of chronic diffuse scle-rosing osteo- myelitis, which makes diagnosis of the disease difficult in symptomatic cases. Moreover the jaws may be suscepti- ble to osteomyelitis, which may mask the underlying FCOD in some cases. The case reported here is that of a 56 year old Indian female patient with long standing FCOD invol-ving the maxi- lla and the mandible, who was asymptomatic till all her teeth were extracted for fabrica-tion of complete dentures. The patient experienced symptoms of pain, swelling and purulent discharge soon after the use of dentures and was treated by surgical removal of the affected bone. The same symptoms recurred in other areas of the jaw over a period of time and these areas were treated surgica-lly. The patient subsequently presented with pain in the man- dibular left posterior region of ten days duration, and was diagnosed as FCOD with superimposed Actinomycotic Osteomyelitis based on his-topathology and Gram's stain, and was treated by surgical removal of the affected bone followed by hyperbaric oxygen therapy (HBO). The radiograph of the surgical site showed good amount of bone regeneration within six months of HBO therapy without recurrence of the FCOD in the same area till date.
    Journal of Clinical and Experimental Dentistry. 01/2010;
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    ABSTRACT: Objectives: Assessment of the cell proliferation rate in tissues can be one of the markers for impending malignancy in precancers. The state of activation and the proliferation activity of the cells can be assessed by the frequency of silver stained Nucleolar Organiser regions (AgNOR) within the nuclei which is significantly higher in malignant cells. The present study was carried out to analyze the distribution of the AgNOR in oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC), and in their various histological grades, and to assess if the AgNOR distribution could give information on the malignant potentiality in premalignant lesions and aggressiveness of the malignant lesions. Study design: The study specimens comprised of 35 archival cases, of which 15 cases were of OL and 20 cases of OSCC. The specimens were stained by hematoxylin and eosin and modified silver staining method of Ploton et al. for the Nucleolar Organiser Regions. The specimens were analyzed independently by the two observers and was further statistically analysed. Results: The mean AgNOR count in OL was 2.80 ±0.50 and in cases of OSCC was 5.71± 1.08. The mean AgNOR count in OL cases of mild dysplasia was 2.59 ±0.66, in moderate dysplasia was 2.92± 0.43 and in severe dysplasia was 2.79. The mean AgNOR count in cases of well differentiated OSCC was 5.73± 1.62 and in cases of moderately differentiated OSCC was 5.67±1.19. Conclusion: The mean AgNOR count was higher in cases of OSCC as compared to cases of OL, and the AgNOR counts increased with the increase in the grades of dysplasia indicating a higher proliferative rate with increase in dysplasia.