H. Trabelsi

University of Sfax, Şafāqis, Şafāqis, Tunisia

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Publications (55)26.34 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: Geotrichum capitatum is an uncommon cause of invasive infections in immunocompromised patients, particularly those with hematological malignancies and severe neutropenia. The aim of this study was to report the cases of invasive geotrichosis in our hospital. It is a retrospective study of invasive geotrichosis diagnosed in the Laboratory of Parasitology-Mycology of the UH Habib Bourguiba, Sfax, from January 2005 to August 2013. Six cases of invasive Geotrichum infections were diagnosed. There were three men and three women. The mean age was 35 years. Five patients have acute myeloid leukemia with a profound neutropenia, and one patient was hospitalized in the intensive care unit for polytraumatism. Clinically, the prolonged fever associated with pulmonary symptoms was the predominant symptom (n = 5). Geotrichum capitatum was isolated in one or more blood culture. Two patients had urinary tract infections documented by multiple urine cultures positive for G. capitatum. Five patients received conventional amphotericin B alone or associated with voriconazole. The outcome was fatal in four cases. Invasive geotrichosis is rare, but particularly fatal in immunocompromised patients. Approximately, 186 cases have been reported in the literature. The prognostic is poor with mortality over 50 %. So, early diagnosis and appropriate management are necessary to improve prognosis.
    Mycopathologia 02/2015; 179(5-6). DOI:10.1007/s11046-015-9869-2 · 1.55 Impact Factor
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    ABSTRACT: Yarrowia lipolytica is weakly pathogenic yeast, which is rarely isolated from the blood. We report unusual cases of Y. lipolytica fungemia occurred between October 2012 and June 2014 in the intensive care unit (ICU) of the UH Habib Bourguiba Sfax. During this period, 55 cases of Y. lipolytica septicemia were diagnosed. There were 44 men and 11 women (sex ratio = 4).The median age was 43 years. The broad-spectrum antibiotics (100 %), the catheterization (96 %), and the prolonged hospitalization in ICU (91 %) were the main risk factors. Patients were hospitalized in ICU, mostly, for polytraumatism (45.4 %), pneumopathy (9 %), and post-operative complications (7 %). Fever unresponsive to broad-spectrum antibacterial therapy was the predominant sign of infection (83.6 %). Y. lipolytica was isolated in one or several blood cultures (14.5 %) and in the catheter tip culture of nine patients (16.3 %).Treatment was based on intravenous amphotericin B (58.2 %), fluconazole (45.4 %) and/or removal catheter (69 %). Apyrexia or blood cultures sterilization was obtained for 34 patients (61.8 %). Y. lipolytica candidemia is an opportunistic and emerging human yeast pathogen. It can reach to the bloodstream of immunocompromised or critically ill patients during hospitalization through intravascular catheterization. Further clinical data need to be evaluated for formulating management strategies of seriously ill patients infected with uncommon fungal agents.
    Mycopathologia 01/2015; 179(5-6). DOI:10.1007/s11046-015-9859-4 · 1.55 Impact Factor
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    ABSTRACT: SUMMARY Phased antenna array design is one of the most important electromagnetic optimization problems. This research combined the Taguchi method and artificial intelligence methods, used them as the prediction tool in designing parameters for the communication system, and then constructed a set of the optimal parameter analysis flow and steps. In this paper, we present an application of artificial neural networks in the electromagnetic domain. We particularly look at the multilayer perceptron network, which has been the most used of artificial neural networks architectures both in the electromagnetic domain and in the Taguchi optimization technique and describes the Taguchi method to optimize the excitations elements of the linear array to produce a radiation pattern with minimum side lobe level and null placement control. This paper investigates how the implementation of the signal processing in hardware affects the performance of the adaptive array antenna. The investigation is confined to uplink or receive antenna array only. Results of a prototype of antenna array with feeding values designed using the proposed techniques are also presented. Copyright © 2013 John Wiley & Sons, Ltd.
    International Journal of Communication Systems 12/2014; 27(12). DOI:10.1002/dac.2625 · 1.11 Impact Factor
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    ABSTRACT: Fungal keratitis is responsible for a significant burden of blinding disease in the developing world. The aim of this study was to determine the etiological agents, predisposing factors and therapy of keratomycosis in our region. Retrospective study of 60 patients with clinically and cultured confirmed fungi keratitis, who were attended at department of mycology in Sfax (1995 to 2012). The mean age of patients was 47.2 years (sex ratio: 1.58). At least, one presumed predisposing factor was identified in 83.3% of cases. Corneal traumatism was established as the most common predisposing factor (61.6%) with vegetative matter (42.4%). Patients had corneal ulcer in 40% or abscess in 47.6%. All cases were positive on direct microscopy and 93% of cultures were positive. Filamentous fungi form the major etiologic agents (83%): Fusarium species (49% with F. solani [66%]), Aspergillus sp. (22%), Alternaria (5%), Scedosporium sp. (2%); and non-identified mold in (5%). Yeast were identified in 17% of cases. Topical agents were used in 97% of cases: ketoconazole 2%, amphotericin B (0.5%). Fluconazole per os was administrated for 11% of cases, itraconazole (2 cases) and voriconazole (one case). Keratoplasty was indicated for 27% of cases. The outcome was favorable in 16% of patients. Among the patients, 71% had persistent corneal deposit sequelae. Four patients lost the eyeball. Corneal traumatism was the principal risk factor for fungal keratitis in young and middle-aged farmers. Fusarium solani is the predominant cause in Sfax. Early diagnosis, coupled with appropriate treatment, is crucial for increasing the chance of complete recovery. Copyright © 2014 Elsevier Masson SAS. All rights reserved.
    Journal de Mycologie Médicale/Journal of Medical Mycology 10/2014; 24(4). DOI:10.1016/j.mycmed.2014.06.047 · 0.40 Impact Factor
  • Journal de Mycologie Médicale/Journal of Medical Mycology 06/2014; 24(2):e88-e89. DOI:10.1016/j.mycmed.2014.01.108 · 0.40 Impact Factor
  • Journal de Mycologie Médicale/Journal of Medical Mycology 06/2014; 24(2):e82. DOI:10.1016/j.mycmed.2014.01.090 · 0.40 Impact Factor
  • Journal de Mycologie Médicale/Journal of Medical Mycology 06/2014; 24(2):e83. DOI:10.1016/j.mycmed.2014.01.092 · 0.40 Impact Factor
  • Journal francais d'ophtalmologie 05/2014; 37(6). DOI:10.1016/j.jfo.2013.10.005 · 0.36 Impact Factor
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    ABSTRACT: The Trichophyton mentagrophytes complex is the main cause of superficial mycoses in humans and animals. Molecular research has provided useful insights into the taxonomy of this complex to overcome the challenges with conventional diagnostics. The aim of this study was to identify, type and differentiate anthropophilic and zoophilic species of the T. mentagrophytes complex. Sixty clinical samples identified as T. mentagrophytes by morphological characteristics were isolated using polymerase chain reaction-restriction fragment length polymorphism and sequence analysis of the internal transcribed spacer (ITS) regions. The identification of our strains by conventional methods was confirmed using polymerase chain reaction (PCR) sequencing in 93.34% of the cases. The strains under investigation were recategorised as T. rubrum (Tr2711). In addition, PCR products were independently digested with the restriction endonucleases, MvaI and HinfI, to produce a single dominant profile for T. interdigitale. ITS sequence analysis revealed a polymorphism in the ITS1 and 5.8S regions. Analysis of the consensus sequences distinguished four types of genotypes among our T. interdigitale species. Moreover, ITS type I was the dominant genotype characterising the anthropophilic variant of T. interdigitale. The phylogenetic study showed that only 5% of our strains were zoophilic. PCR sequencing was useful for distinguishing anthropophilic and zoophilic species of T. interdigitale, in which the differentiation is relevant because it helps to prescribe the correct treatment and to identify the surrounding source of infection.
    Mycoses 03/2014; 57(8). DOI:10.1111/myc.12181 · 1.81 Impact Factor
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    ABSTRACT: The paper discussed the implementation of the hybrid algorithm to modelling the multilayer planar circuit by combine the FDFD method and WCIP method. The finite difference frequency domain (FDFD) algorithm can be used to modelling the 3D discontinuity structure, with the open region modelled by iterative method. The well agreement between our method and original FDFD method demonstrated the validity and flexibility of the method. Memory requirement is greatly reduced by using DDM.
    2014 11th International Multi-Conference on Systems, Signals & Devices (SSD); 02/2014
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    Journal francais d'ophtalmologie 01/2014; · 0.36 Impact Factor
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    ABSTRACT: Invasive fungal infections are a major complication and an important cause of morbidity and mortality among solid organ transplant recipients. Their diagnosis is difficult and their prognosis is often pejorative. The aim of this study was to report the cases of invasive fungal infections in renal transplant recipients in Habib Bourguiba Sfax university hospital and to identify the main fungal agents. It is a retrospective study of invasive fungal infections in renal transplant recipient reported in our hospital from January 1995 to February 2013. Invasive fungal infections were diagnosed in 11 cases (3.4%) among 321 renal transplant recipients. These infections included four cases of pneumocystosis, two cases of candidiasis, two cases of aspergillosis, two cases of cryptococcosis and one case of mucormycosis. There were six men and five women. The mean age was 37 years. The infection was late in 63% of cases (>3 months after transplantation). The prolonged corticosteroid and immunosuppressive therapy were the main risk factors (100%) followed by renal failure (45%), graft rejection (45%), broad spectrum antibiotics (45%), CMV infection (36%), neutropenia (36%) and dialysis (18%). The evolution under treatment was favourable only in two cases (18%). Invasive fungal infections are not common among kidney transplant recipients. However, they remain an important cause of morbidity and mortality in this group of patients. Prevention, early diagnosis and appropriate management are necessary to improve prognosis and reduce mortality rate.
    Journal de Mycologie Médicale/Journal of Medical Mycology 09/2013; DOI:10.1016/j.mycmed.2013.07.052 · 0.40 Impact Factor
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    ABSTRACT: The genus Fusarium, initially known for its important agro-economic impact, is more and more often implicated in human pathology. In fact, multiples allergic, toxic and infectious manifestations are more reported in immunocompetent and immunocompromised hosts. The objective of our study was to analyse the epidemiological, mycological and clinical features of fusariosis reported in our CHU. Eighty-seven cases of Fusarium infections were collected: 34 cases of onychomycosis (39%), 26 cases of intertrigos (30%), 25 cases of keratomycosis (29%), one case of atypical invasive fusariosis due to Fusarium oxysporum species complex (FOSC) and one case of localized gingivolabial fusariosis due to Fusarium solani species complex (FSSC) in a patient with leukemia in phase of deep bone marrow aplasia, whose outcome was favorable after exiting of aplasia period and a treatment by amphotericine B. The case of pseudotumoral cutaneous fusariosis to F. oxysporum complicated with osteolysis and septic arthritis occurred in a pregnant woman without any immune deficit. The evolution was fatal in spite of prescription of multiple systemic antifungals. Concerning keratomycosis, Fusarium was the first agent responsible for these infections (43%). The corneal traumatism was found in 37.5% of cases and FSSC was the most isolated (72%). For superficial dermatomycosis, Fusarium was the third agent of onychomycosis in molds (25%). The most isolated species were FSSC (68%) and FOSC (20%). The intertrigo frequency was 0.07% and they were mostly caused by FSSC (84%) and FOSC (16%). Fusarium is an important cause of mold infections in our region. So, the species identification is useful because some species are resistant to the most common systemic antifungal agents.
    Journal de Mycologie Médicale/Journal of Medical Mycology 06/2013; 23(2):130–135. DOI:10.1016/j.mycmed.2013.04.003 · 0.40 Impact Factor
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    ABSTRACT: The genus Fusarium, initially known for its important agro-economic impact, is more and more often implicated in human pathology. In fact, multiples allergic, toxic and infectious manifestations are more reported in immunocompetent and immunocompromised hosts. The objective of our study was to analyse the epidemiological, mycological and clinical features of fusariosis reported in our CHU. Eighty-seven cases of Fusarium infections were collected: 34 cases of onychomycosis (39%), 26 cases of intertrigos (30%), 25 cases of keratomycosis (29%), one case of atypical invasive fusariosis due to Fusarium oxysporum species complex (FOSC) and one case of localized gingivolabial fusariosis due to Fusarium solani species complex (FSSC) in a patient with leukemia in phase of deep bone marrow aplasia, whose outcome was favorable after exiting of aplasia period and a treatment by amphotericine B. The case of pseudotumoral cutaneous fusariosis to F. oxysporum complicated with osteolysis and septic arthritis occurred in a pregnant woman without any immune deficit. The evolution was fatal in spite of prescription of multiple systemic antifungals. Concerning keratomycosis, Fusarium was the first agent responsible for these infections (43%). The corneal traumatism was found in 37.5% of cases and FSSC was the most isolated (72%). For superficial dermatomycosis, Fusarium was the third agent of onychomycosis in molds (25%). The most isolated species were FSSC (68%) and FOSC (20%). The intertrigo frequency was 0.07% and they were mostly caused by FSSC (84%) and FOSC (16%). Fusarium is an important cause of mold infections in our region. So, the species identification is useful because some species are resistant to the most common systemic antifungal agents.
    Journal de Mycologie Médicale/Journal of Medical Mycology 05/2013; · 0.40 Impact Factor
  • Journal de Mycologie Médicale/Journal of Medical Mycology 03/2013; 23(1):81. DOI:10.1016/j.mycmed.2012.12.035 · 0.40 Impact Factor
  • Annales de Dermatologie et de Vénéréologie 03/2013; 23(1):82. DOI:10.1016/j.mycmed.2012.12.038 · 0.67 Impact Factor
  • Journal de Mycologie Médicale/Journal of Medical Mycology 03/2013; 23(1):82. · 0.40 Impact Factor
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    Journal de Mycologie Médicale/Journal of Medical Mycology 03/2013; 23(1):77–78. DOI:10.1016/j.mycmed.2012.12.025 · 0.40 Impact Factor
  • H. Trabelsi, A. Chbeb, A. Sellami
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    ABSTRACT: In this paper a discrete-time model for Permanent Magnet Synchronous Motor (PMSM) based on the Explicit Euler method is presented. Thus, an advanced application of the discrete variable structure control theory using a discrete time varying sliding surface is designed for the tracking of the rotor velocity. First, modeling and simulation of the PMSM supplied by an inverter is presented. Then, closed loop simulations of the RST control and the discrete time sliding mode control (DSMC) are realized. The obtained results from the two approaches are finally compared in terms of good performances.
    Electrical Engineering and Software Applications (ICEESA), 2013 International Conference on; 01/2013
  • Annales de Dermatologie et de Vénéréologie 12/2012; 139(12):B236. DOI:10.1016/j.annder.2012.10.417 · 0.67 Impact Factor

Publication Stats

92 Citations
26.34 Total Impact Points

Institutions

  • 2011–2015
    • University of Sfax
      • • Department of Medicine A
      • • Laboratory of Parasitology
      Şafāqis, Şafāqis, Tunisia
  • 2006–2011
    • University of Tunis El Manar
      • • Faculty of Mathematical, Physical and Natural Sciences
      • • Department of Physics
      Tunis-Ville, Tūnis, Tunisia
  • 2003–2011
    • Faculté des Sciences de Tunis
      • Department of Physics
      Tunis-Ville, Tūnis, Tunisia
  • 2010
    • Hedi Chaker Hospital
      Şafāqis, Şafāqis, Tunisia