Hanaa Abuo-Melha

King Khaled Hospital, Hayil, Ḩāʼil, Saudi Arabia

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Publications (1)2.35 Total impact

  • Hanaa Abuo-Melha · A.A. Fadda ·
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    ABSTRACT: A series of arylpicolino and/or isonicotinohydrazonyl cyanide 2a-d and 4a-f were prepared by coupling the approprite aryl diazonium salt with 2-cyanomethyl and/or 4-cyanomethyl-pyridine, respectively. These compounds were characterized by analytical and spectral analyses and screened for their antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and antifungal activity. Among the synthesized compounds, N'-(4-phenyldiazenyl)phenylisonicotinohydrazonyl cyanide 4f showed a significant activity toward both Gram-positive, Gram-negative bacteria and exhibit the most potent in vitro antifungal with MIC's (625 μg/mL) against Aspergillus nieger.
    Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 04/2012; 89:123-8. DOI:10.1016/j.saa.2011.12.054 · 2.35 Impact Factor

Publication Stats

11 Citations
2.35 Total Impact Points


  • 2012
    • King Khaled Hospital
      Hayil, Ḩāʼil, Saudi Arabia