Shoji Hirasaki,
Kazutoshi Murakami,
Takaaki Mizushima,
Kazuyoshi Ohmori,
Seiko Fujita,
Yoshihisa Hanayama,
Tatsuya Kanamori,
Ryo Yokota,
Hirotaka Ebara,
Nobuchika Kusano,
Chieko Kudo, Tomoko Yamaguchi,
Teiji Akagi,
Norio Koide
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ABSTRACT: A 27-year-old woman visited our hospital because of high fever. She had been diagnosed as 22q11.2 deletion syndrome (22q11.2DS) due to her cardiac history (tetralogy of Fallot), thymic hypoplasia and 22q11.2 deletion. She had a normal CD4/CD8 ratio, a slightly decreased lymphocyte count and normal serum immunoglobulin levels. Blood cultures were positive for Staphylococcus lugdunensis (S. lugdunensis). Infection route of S. lugdunensis in this case was unclear. The patient was successfully treated with several intravenous antibiotics. Infection should be considered when managing patients with 22q.11.2DS. regardless of whether their immune system is impaired.
Internal Medicine 01/2012; 51(4):377-80. · 0.94 Impact Factor
