Zhenjiang Zhang

Publications (2)13.88 Total impact

• Article: Gold nanorods based platforms for light-mediated theranostics.

  Zhenjiang Zhang, Jing Wang, Chunying Chen
  [show abstract] [hide abstract]
  ABSTRACT: Due to their tunable surface plasmon and photothermal effects, gold nanorods (AuNRs) have proved to be promising in a wide range of biomedical applications such as imaging, hyperthermia therapy and drug delivery. All these applications can be remotely controlled by near infrared (NIR) light which can penetrate deep into human tissues with minimal lateral invasion. AuNRs thus hold the potential to combine both imaging diagnosis and therapeutic treatment into one single system and function as a NIR light-mediated theranostic platform. Herein we review recent progress in diagnostic and therapeutic applications of AuNRs with a highlight on combined applications for theranostic purposes.
  Theranostics. 01/2013; 3(3):223-38.
• Article: Mesoporous silica-coated gold nanorods as a light-mediated multifunctional theranostic platform for cancer treatment.

  Zhenjiang Zhang, Liming Wang, Jing Wang, Xiumei Jiang, Xiaohui Li, Zhijian Hu, Yinglu Ji, Xiaochun Wu, Chunying Chen
  [show abstract] [hide abstract]
  ABSTRACT: Mesoporous silica-coated gold nanorods (Au@SiO(2)) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of Au@SiO(2) is visualized through two-photon imaging. With doxorubicin hydrochloride loaded, Au@SiO(2)-DOX show two light-mediated therapeutic modes: low power density laser-triggered drug release for chemotherapy, and high power density laser-induced hyperthermia, which suggest the potential for in-vivo applications.
  Advanced Materials 02/2012; 24(11):1418-23. · 13.88 Impact Factor