Payman Samavarchi-Tehrani

Publications (2)11.4 Total impact

• Article: Transcription Factor-mediated Epigenetic Reprogramming.

  Camille Sindhu, Payman Samavarchi-Tehrani, Alexander Meissner
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  ABSTRACT: Input from various signaling pathways in conjunction with specific transcription factors (TFs), noncoding RNAs, and epigenetic modifiers governs the maintenance of cellular identity. Endogenous or exogenous TFs operate within certain boundaries, which are set, in part, by the cell type-specific epigenetic landscape. Ectopic expression of selected TFs can override the cellular identity and induce reprogramming to alternative fates. In this minireview, we summarize many of the classic examples and a large number of recent studies that have taken advantage of TF-mediated reprogramming to produce cell types of biomedical relevance.
  Journal of Biological Chemistry 09/2012; 287(37):30922-31. · 4.77 Impact Factor
• Article: Epigenomics and chromatin dynamics.

  Veronika Akopian, Michelle M Chan, Kendell Clement, Christina Galonska, Casey A Gifford, Elizabeth Lehtola, Jing Liao, Payman Samavarchi-Tehrani, Camille Sindhu, Zachary D Smith, Alexander M Tsankov, Jamie Webster, Yingying Zhang, Michael J Ziller, Alexander Meissner
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  ABSTRACT: A report of the 'Joint Keystone Symposium on Epigenomics and Chromatin Dynamics', Keystone, Colorado, 17-22 January 2012.
  Genome biology 02/2012; 13(2):313. · 6.63 Impact Factor