Bernardo Hernández-Prado

University of Washington Seattle, Seattle, Washington, United States

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Publications (34)72.44 Total impact

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    ABSTRACT: BACKGROUND: Recent evidence suggests that serum uric acid (SUA) can be an inexpensive and easy-to-obtain indicator of cardiovascular risk (CR). This is especially important in developing countries with high prevalence of cardiovascular disease. We examined the association between SUA levels and 10-year global CR among university workers from the State of Mexico, Mexico. METHODS: A case-control study nested within a cohort was conducted between 2004 and 2006. Anthropometric measures, lifestyle variables, family background and CR factors were assessed. The analysis estimated odds ratios using conditional logistic regression. RESULTS: The study included 319 cases with CR and 638 controls. Subjects in the upper tertile of SUA had 48.0% higher odds of having an elevated CR than those in the lower tertile (OR = 1.48, 95% CI: 1.04 - 2.10) in the crude analysis, but the association was non-significant when adjusting for other covariates. Among physically inactive individuals, being in the third tertile of SUA doubled the odds of high CR, compared with those who perform physical activity three or more hours per week being in the first tertile of SUA (OR = 2.35, 95% CI: 1.24 - 4.45). CONCLUSION: Serum concentration of uric acid is associated with 10-year global CR among individuals with high levels of physical inactivity.
    BMC Public Health 05/2013; 13(1):415. · 2.08 Impact Factor
  • Filipa deCastro, Nora Hinojosa-Ayala, Bernardo Hernandez-Prado
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    ABSTRACT: We explored factors associated with postnatal depression and further evaluated whether any of these risk and protective factors are specific for adolescent mothers. Data concerning depression levels, family and individual factors were collected in a cross-sectional study which surveyed 298 women in Monterrey, N.L., Mexico. Mean maternal age was 24.64 years, and 27.18% of the mothers were between 14 and 19 years old. Prevalence of postnatal depression was higher in adolescents (16.05%) than in adult mothers (14.29%) but, on average, this difference was not significant. The association between individual factors and postnatal depression for both adult and adolescent mothers was explored. Our results revealed that social support is significantly associated with less possibility of postnatal depression in both groups, and that this effect is stronger for adolescents (OR=0.81) than for adults (OR=0.92). For the sample as a whole postnatal depression was associated with lower levels of education, reported fear during labor and living with partner. We also found that having a girl greatly increased the possibility of postnatal depression. We conclude that social support is a protective factor associated with postnatal depression, especially for adolescents.
    Journal of Psychosomatic Obstetrics & Gynecology 11/2011; 32(4):210-7. · 1.59 Impact Factor
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    ABSTRACT: To present the main results of the regional situation diagnosis and intervention plan developed in 2010 as part of the planning activities of the Mesoamerican Health System by the Working Group on Maternal, Reproductive and Neonatal Health. A group of experts and representatives from countries in the region (Central America and nine southern Mexican states) conducted an exhaustive review of available data to construct a situational analysis and a review of effective practices for improving maternal, reproductive and neonatal health. Finally, the group proposed a regional action plan, defining regional goals and specific interventions. The situational diagnosis suggests that, although there has been progress in the last 10 years, maternal and neonatal mortality rates are still unnaceptably high in the region, with a substantial variability across countries. The group proposed as a regional goal the reduction of maternal and neonatal mortality in accordance with the Millenium Development Goals. The regional plan recommends specific maternal and neonatal health interventions emphasizing obstetric and neonatal emergency care, skilled birth attendance and family planning. The plan also includes a five year implementation strategy, along with training and evaluation strategies. The regional plan for maternal, neonatal and reproductive health has the potential to be successful, provided it is effectively implemented.
    Salud publica de Mexico 01/2011; 53 Suppl 3:S312-22. · 0.94 Impact Factor
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    ABSTRACT: To present the main results of the regional situation diagnosis and intervention plan developed in 2010 as part of the planning activities of the Mesoamerican Health System by the Working Group on Maternal, Reproductive and Neonatal Health. A group of experts and representatives from countries in the region (Central America and nine southern Mexican states) conducted an exhaustive review of available data to construct a situational analysis and a review of effective practices for improving maternal, reproductive and neonatal health. Finally, the group proposed a regional action plan, defining regional goals and specific interventions. The situational diagnosis suggests that, although there has been progress in the last 10 years, maternal and neonatal mortality rates are still unnaceptably high in the region, with a substantial variability across countries. The group proposed as a regional goal the reduction of maternal and neonatal mortality in accordance with the Millenium Development Goals. The regional plan recommends specific maternal and neonatal health interventions emphasizing obstetric and neonatal emergency care, skilled birth attendance and family planning. The plan also includes a five year implementation strategy, along with training and evaluation strategies. The regional plan for maternal, neonatal and reproductive health has the potential to be successful, provided it is effectively implemented.
    Salud publica de Mexico 12/2010; 53:s312-s322. · 0.94 Impact Factor
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    ABSTRACT: Rarely have researchers explored the distribution of a programme's effects in a population, tending to focus on unidimensional measures of impact instead. This can mask heterogeneity of effects, making it difficult to identify subsets of the population for whom impacts might differ from a population average. The authors exploit the design of Mexico's Oportunidades programme to construct measures of the heterogeneous impacts of the programme on contraception and compare these with conventional effect estimates. They find that the latter, while probably reliable for particular types of effects, fail to uncover the substantial programme impacts on the poorest women in rural Mexico.
    Journal of Development Effectiveness 01/2010; 2(1):74-86. · 0.92 Impact Factor
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    ABSTRACT: OBJECTIVE:To evaluate the association between time of postpartum discharge and symptoms indicative of complications during the first postpartum week. MATERIALS AND METHODS: Women with vaginal delivery at a Mexico City public hospital, without complications before the hospital discharge, were interviewed seven days after delivery. Time of postpartum discharge was classified as early (<24 hours) or late (>25 hours). The dependent variable was defined as the occurrence and severity of puerperal complication symptoms. RESULTS:Out of 303 women, 208 (68%) were discharged early. However, women with early discharge and satisfactory prenatal care had lower odds of presenting symptoms in early puerperium than women without early discharge and inadequate prenatal care (OR 0.36; 95% confidence intervals = 0.17-0.76). CONCLUSIONS:There was no association between early discharge and symptoms of complications during the first postpartum week; the odds of complications were lower for mothers with early discharge and satisfactory prenatal care.
    Salud publica de Mexico 06/2009; 51(3):212-218. · 0.94 Impact Factor
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    ABSTRACT: To assess the association of time spent viewing television, videos and video games with measures of fat mass (BMI) and distribution (triceps and subscapular skinfold thicknesses (TSF, SSF)). Cross-sectional validated survey, self-administered to students to assess screen time (television, videos and video games) and lifestyle variables. Trained personnel obtained anthropometry. The association of screen time with fat mass and distribution, stratified by sex, was modelled with multivariable linear regression analysis, adjusting for potential confounders and correlation of observations within schools. State of Morelos, Mexico. Males (n 3519) and females (n 5613) aged 11 to 18 years attending urban and rural schools in Morelos. In males, screen time of >5 h/d compared with <2 h/d was significantly associated with a 0.13 (95% CI 0.04, 0.23) higher BMI Z-score, 0.73 mm (95% CI 0.24, 1.22) higher SSF and 1.08 mm (95% CI 0.36, 1.81) higher TSF. The positive association of screen time with SSF was strongest in males aged 11-12 years. Sexual maturity appeared to modify the association in females; a positive association between screen time and SSF was observed in those who had not undergone menarche (P for trend = 0.04) but not among sexually mature females (P for trend = 0.75). Screen time is associated with fat mass and distribution among adolescent males in Mexico. Maturational tempo appears to affect the relationship of screen time with adiposity in boys and girls. Findings suggest that obesity preventive interventions in the Mexican context should explore strategies to reduce screen time among youths in early adolescence.
    Public Health Nutrition 03/2009; 12(10):1938-45. · 2.25 Impact Factor
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    ABSTRACT: To determine the association between physical activity and overweight/obesity in Mexican adults. Cross-sectional design. Adults 20 to 69 years of age were included in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006). The dependent variable was overweight/obesity and the independent variable was recalled physical activity. Analysis was by logistic regression, adjusting for sex, age, residence area, region, socioeconomic status, indigenous ethnicity, smoking, schooling, work activity, alcohol consumption and sitting time. Data from 15 901 adults were analyzed. The prevalence of overweight/obesity had an inverse association with physical activity among men but not among women. The practice of physical activity was negatively associated with the prevalence of overweight/obesity only in adult men. These results underscore the importance of promoting physical activity to prevent and control overweight/obesity.
    Salud publica de Mexico 01/2009; 51 Suppl 4:S621-9. · 0.94 Impact Factor
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    ABSTRACT: To determine whether screen time and physical activity is related to overweight or obesity in adolescents. Cross-sectional design. Adolescents aged 10 to 19 were included in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006). The dependent variable was overweight or obesity; the independent variable was screen time. A logistic regression model was created to estimate the relationship of overweight and obesity to various factors, including screen time, physical activity, study vs. no study, age, sex, indigenous ethnicity, alcohol consumption and tobacco use. A total of 18 784 adolescents were included. A positive relation between screen time and overweight and obesity was found. Screen time is associated with overweight and obesity in Mexican adolescents.
    Salud publica de Mexico 01/2009; 51 Suppl 4:S613-20. · 0.94 Impact Factor
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    ABSTRACT: To evaluate the association between time of postpartum discharge and symptoms indicative of complications during the first postpartum week. Women with vaginal delivery at a Mexico City public hospital, without complications before the hospital discharge, were interviewed seven days after delivery. Time of postpartum discharge was classified as early (<24 hours) or late (>25 hours). The dependent variable was defined as the occurrence and severity of puerperal complication symptoms. Out of 303 women, 208 (68%) were discharged early. However, women with early discharge and satisfactory prenatal care had lower odds of presenting symptoms in early puerperium than women without early discharge and inadequate prenatal care (OR 0.36; 95% confidence intervals = 0.17-0.76). There was no association between early discharge and symptoms of complications during the first postpartum week; the odds of complications were lower for mothers with early discharge and satisfactory prenatal care.
    Salud publica de Mexico 01/2009; 51(3):212-8. · 0.94 Impact Factor
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    ABSTRACT: To determine the association between overweight and obesity among Mexican school-aged children and participation in the Liconsa milk and the School Breakfast food assistance programs. Data from 15 003 school-aged children included in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006) were analyzed. Information on body mass index (BMI) and participation in food assistance programs was obtained. Descriptive analyses were conducted and logistic regression models were adjusted. Prevalence of overweight and obesity was 17.3% and 9%, respectively. No significant association between overweight and obesity and participation in Liconsa was found. Among school-aged children in the middle socioeconomic status quintile, those enrolled in the School Breakfast program were more likely to be overweight than those not enrolled (OR= 1.6, 95% CI 1.1, 2.3). We found no association between the Liconsa and the School Breakfast programs and overweight or obesity in school-aged children.
    Salud publica de Mexico 01/2009; 51 Suppl 4:S630-7. · 0.94 Impact Factor
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    ABSTRACT: OBJECTIVE: To determine the association between physical activity and overweight/obesity in Mexican adults. MATERIAL AND METHODS: Cross-sectional design. Adults 20 to 69 years of age were included in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006). The dependent variable was overweight/obesity and the independent variable was recalled physical activity. Analysis was by logistic regression, adjusting for sex, age, residence area, region, socioeconomic status, indigenous ethnicity, smoking, schooling, work activity, alcohol consumption and sitting time. RESULTS: Data from 15 901 adults were analyzed. The prevalence of overweight/obesity had an inverse association with physical activity among men but not among women. CCONCLUSIONS: The practice of physical activity was negatively associated with the prevalence of overweight/obesity only in adult men. These results underscore the importance of promoting physical activity to prevent and control overweight/obesity.
    Salud publica de Mexico 12/2008; 51:S621-S629. · 0.94 Impact Factor
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    ABSTRACT: OBJECTIVE: To determine the association between overweight and obesity among Mexican school-aged children and participation in the Liconsa milk and the School Breakfast food assistance programs. MATERIAL AND METHODS: Data from 15 003 school-aged children included in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006) were analyzed. Information on body mass index (BMI) and participation in food assistance programs was obtained. Descriptive analyses were conducted and logistic regression models were adjusted. RESULTS: Prevalence of overweight and obesity was 17.3% and 9%, respectively. No significant association between overweight and obesity and participation in Liconsa was found. Among school-aged children in the middle socioeconomic status quintile, those enrolled in the School Breakfast program were more likely to be overweight than those not enrolled (OR= 1.6, 95% CI 1.1, 2.3). CONCLUSIONS: We found no association between the Liconsa and the School Breakfast programs and overweight or obesity in school-aged children.
    Salud publica de Mexico 12/2008; 51:S630-S637. · 0.94 Impact Factor
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    ABSTRACT: OBJECTIVE: To determine whether screen time and physical activity is related to overweight or obesity in adolescents. MATERIAL AND METHODS: Cross-sectional design. Adolescents aged 10 to 19 were included in the Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006). The dependent variable was overweight or obesity; the independent variable was screen time. A logistic regression model was created to estimate the relationship of overweight and obesity to various factors, including screen time, physical activity, study vs. no study, age, sex, indigenous ethnicity, alcohol consumption and tobacco use. RESULTS: A total of 18 784 adolescents were included. A positive relation between screen time and overweight and obesity was found. CONCLUSIONS: Screen time is associated with overweight and obesity in Mexican adolescents.
    Salud publica de Mexico 12/2008; 51:S613-S620. · 0.94 Impact Factor
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    ABSTRACT: Objetivo: Identificar la influencia de las características reproductivas y el empoderamiento femenino en el uso de servicios de planificación familiar (PF). Material y métodos: Diseño de casos y no casos pareado por controles vecindarios (147 usuarias y 146 no usuarias de servicios de PF de la Secretaría de Salud durante 2003), en dos municipios del estado de Guanajuato, México. Análisis logístico multivariado para identificar diferencias entre usuarias y no usuarias. Resultados: El uso de servicios de PF se asoció positiva y significativamente con poder de decisión de la mujer (alto: RM=3.2; IC95% 1.4-7.4); comunicación con la pareja para el uso de métodos de PF (RM =3.5; IC95% 1.4-9.3), y número de embarazos en su vida (> 6 hijos: RM =4.4; IC95% 1.4-13.8). Conclusiones: El desarrollo de estrategias que involucren a los hombres y que, por otra parte, fomenten y fortalezcan el empoderamiento femenino, puede contribuir a una mayor utilización de servicios de PF.
    Salud publica de Mexico 01/2008; · 0.94 Impact Factor
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    José E Urquieta-Salomón, José L Figueroa, Bernardo Hernández-Prado
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    ABSTRACT: Objective. To estimate the effect of disability and incapacity in health expenditure in poor households in Mexico. Mate- rial and Methods. This is an analysis of baseline survey of the Oportunidades evaluation. Households with siblings with structural disability or incapacity were identified, and health expenditure was estimated. Results. In 15 314 households analyzed, 10.1% had a sibling with structural disability, and 13.4% with mild or severe incapacity. The presence of struc- tural disability was not associated with a higher expenditure in health care. The presence of mild or severe incapacity was associated with 97% higher expenditure in ambulatory care compared with households without incapacity. The poor households have higher health related expenditures. Conclusions. These results indicate that the incapacity to develop day to day activities has a significant impact on the out of pocket health expenditure. This impact is higher in poor households.
    Salud publica de Mexico 01/2008; 50(2). · 0.94 Impact Factor
  • José E Urquieta-Salomón, José L Figueroa, Bernardo Hernández-Prado
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    ABSTRACT: To estimate the effect of disability and incapacity in health expenditure in poor households in Mexico. This is an analysis of baseline survey of the Oportunidades evaluation. Households with siblings with structural disability or incapacity were identified, and health expenditure was estimated. In 15314 households analyzed, 10.1% had a sibling with structural disability, and 13.4% with mild or severe incapacity. The presence of structural disability was not associated with a higher expenditure in health care. The presence of mild or severe incapacity was associated with 97% higher expenditure in ambulatory care compared with households without incapacity. The poor households have higher health related expenditures. These results indicate that the incapacity to develop day to day activities has a significant impact on the out of pocket health expenditure. This impact is higher in poor households.
    Salud publica de Mexico 01/2008; 50(2):136-46. · 0.94 Impact Factor
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    ABSTRACT: The objective of the study was to determine the prevalence and associated factors for temporomandibular disorders (TMD) in a university sample of Campeche, Mexico. A cross-sectional study was carried out in 506 subjects aged 14-25 years. The subjects were requested to answer questionnaires concerning sociodemographic variables, history of stress, lifestyle, and anxiety. The Research Diagnostic Criteria for TMD (RDC/TMD) was used as TMD diagnostic system by four examiners capacitated and standardized. Data were analyzed using binary logistic regression in STATA. The results showed that 46.1% of the subjects exhibited some grade of TMD. Logistic regression analysis with TMD as the dependent variable identified sex (women odds ratio [OR]=1.7), bruxism (OR=1.5), anxiety (OR=1.6), unilateral chewing (OR=1.5), and an interaction between number of tooth loss and stress as the most significant associated variables, thus (1) the effect of having high levels of stress in the group of subjects without tooth loss (OR=1.2; 95% confidence interval [CI]=0.7-1.8) and (2) the effect of having high levels of stress in the group of subjects with at least one tooth lost (OR=2.4; 95% CI=1.01-5.9). The variables associated with diagnosis of pain were principally psychosocial (stress and anxiety), whereas for the non-pain diagnosis group, the variables were clinical, such as bruxism, chewing site preference, and restorations in mouth. We found associations among variables that were similar to findings in other studies, such as bruxism, tooth loss, stress, and anxiety. The final model explains that the effect of stress on TMD depends of the tooth loss, controlling for sex, bruxism, unilateral chewing, and anxiety. Finally, it can be concluded that the variables associated with pain and non-pain diagnosis were of distinct nature.
    Clinical Oral Investigations 04/2006; 10(1):42-9. · 2.20 Impact Factor
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    ABSTRACT: Objective. To estimate the prevalence of maternal and neonatal syphilis, to assess the usefulness of a rapid treponemic diagnostic test, and to evaluate the frequency of screening for syphilis during prenatal care in Mexican women.
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 04/2006; 58(2):119-125. · 0.31 Impact Factor
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    ABSTRACT: To estimate the association between obstetric and socio-demographic characteristics and risk factors related to intra- and extra-hospital maternal mortality in Guatemala during the year 2000. A cross-sectional epidemiologic study was carried out in 649 maternal mortality (MM) cases that occurred in Guatemala during 2000, comparing characteristics of intra- and extra-hospital maternal deaths. Multivariate statistical analysis was conducted using Stata 7.0 software. Out of 649 registered MM cases, 270 (41.6%) were classified as intra-hospital MM and 379 (58.4%) as extra-hospital MM.A larger proportion of deaths occurred in women over 35 years of age (29.28%), those of indigenous ethnicity (65.49%), married or cohabiting (87.83%),who had unpaid employment (94.78%), and without formal education (66.56%). Compared with intra-hospital MM cases,the risk of extra-hospital MM was greater among indigenous women (OR 3.4; CI 95% 2.8-5.3),those who had unpaid employment (OR 8.95; CI 95% 1.7-46.4), a low level of formal education (OR 1.96; CI 95% 1.0-3.8) and hemorrhaging as the immediate cause of death (OR 4.28; CI 95% 2.3-7.9). Although some characteristics of intra- and extra-hospital MM cases are similar, a greater proportion of deaths were extra-hospital. This could be related to the high percentage of the population that lives in rural or marginalized areas, which in addition to certain cultural aspects (related to the fact that most of the population is indigenous) may impede access to health services. The results of this study can be useful for determining intervention strategies to prevent maternal mortality in intra- and extra-hospital contexts in Guatemala.
    Salud publica de Mexico 01/2006; 48(3):183-92. · 0.94 Impact Factor

Publication Stats

132 Citations
72.44 Total Impact Points

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Institutions

  • 2011–2013
    • University of Washington Seattle
      • Institute for Health Metrics and Evaluation
      Seattle, Washington, United States
  • 2002–2011
    • Instituto Nacional de Salud Pública
      • The Center for Population Health Research
      Cuernavaca, Morelos, Mexico