Yuan-Wei Liang

University of Jinan (Jinan, China), Chi-nan-shih, Shandong Sheng, China

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Publications (4)2.5 Total impact

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    ABSTRACT: The first total synthesis of the furanolactam fuscain is reported. The key step in the synthesis was the formation of seven-membered lactam by acylation of a furan ring using the mild Lewis acid CuSO4·5H2O.
    Journal of Chemical Research 12/2012; 36(12). DOI:10.3184/174751912X13528167435099 · 0.63 Impact Factor
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    Tao Lu · Xiao-Jian Liao · Yuan-Wei Liang · Shi-Hai Xu
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    ABSTRACT: In the title compound, C(8)H(3)F(4)NO(3), the carb-oxy group lies nearly in the plane of the ring with a C-C-C-O torsion angle of -10.5 (4)°. The carbamoyl group is almost perpendic-ular to the benzene ring [C-C-C-O torsion angle = 82.2 (4) °]. In the crystal, molecules are linked via O-H⋯O and N-H⋯O hydrogen bonds involving the carbamoyl and carb-oxy groups.
    Acta Crystallographica Section E Structure Reports Online 10/2012; 68(Pt 10):o2864. DOI:10.1107/S1600536812036549 · 0.35 Impact Factor
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    ABSTRACT: Two new pentahydroxylated steroids, (3β,12β,16β,23E)-cholesta-5,23-diene-3,12,16,20,25-pentaol (1) and (3β,12β,16β)-cholesta-5,25(26)-diene-3,12,16,20,24-pentaol (2), were isolated from the EtOH extract of the South China Sea gorgonian Subergorgia suberosa. In addition, four known steroids were detected. The structures of these compounds were established by spectroscopic methods and comparison of their data with those of the related known compounds. In addition, the cyctotoxicities of the compounds were evaluated against selected cancer cell lines.
    Chemistry & Biodiversity 02/2012; 9(2):370-5. DOI:10.1002/cbdv.201100031 · 1.52 Impact Factor
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    ABSTRACT: To study the secondary metabolites from the marine sponge Phakellia fusca epiphytic fungi. The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromatography and preparative TLC. The structures were elucidated by means of physiochemical properties and spectroscopic analyses. Four compounds were separated and identified as: cyclo-(L-Val-L-Pro) (1), cyclo-(L-Phe-L-Pro) (2), cyclo-(L-Tyr-L-Pro) (3), cyclo-(3-hydroxy-4-methyldecanoyl-Gly-L-Val-D-Leu-L-Ala-L-Phe) (4). Compounds 1-4 are obtained from the marine sponge Phakellia fusca epiphytic fungi for the first time.
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 12/2011; 34(12):1877-9.