Marco Oliva

University of Pavia, Ticinum, Lombardy, Italy

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Publications (6)0 Total impact

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    ABSTRACT: Aim: The aim of this paper was to evaluate by clinical and non-invasive instrumental evaluations, the efficacy and the tolerance of a cosmetic slimming treatment for menopausal women used topically (for at least 3 years) under dermatological control. Methods: A controlled double blind, randomised study was performed to compare the slimming efficacy of the cosmetic slimming treatment versus placebo after 4 weeks of treatment. Results: Cosmetic slimming treatment twice a day for 4 weeks reduced abdomen and hips fat, with no significant variation in body weight in comparison with the placebo. Conclusion: The present study evidenced the clinical effectiveness and women satisfaction of a slimming treatment specifically studies for postmenopausal adipose tissue with potential interesting consequences on measures of quality of life and on health-care programs.
    Minerva ginecologica 02/2013; 65(1):79-88.
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    ABSTRACT: The purpose of this double-blind randomised study was to evaluate the efficacy and tolerability of a new cosmeceutical formulation to reduce light-to-moderate localised adiposities symmetrically distributed on the waist and hips. The study was conducted in accordance with the ethical principles derived from the Declaration of Helsinki and Good Clinical Practices. After obtaining a properly detailed informed consent, a group of 110 female volunteers (aged 30.55 years; mean age 48 years) were instructed to blindly apply two apparently identical topical products, rubbing them twice every day on selected localised adiposities for a total duration of 4 weeks. The active formulation and placebo cream were blindly assigned to all study subjects. Objective evaluation was carried out at four fixed time intervals. Clinical assessment consisted of standardised measurements of anatomical circumferences; standardised ultrasound-assisted measurements of subcutaneous adipose tissue; and standardised plicometry. All anatomical regions treated using the cosmeceutical formulation showed a significant reduction of localised adiposities compared with placebo. No adverse events and/or complications were observed in both active and placebo treated areas. Subjective evaluation was performed using self.assessment questionnaires. All study subjects considered intrinsic cosmeceutical characteristics generally good, without significant differences between formulations. Subjective perception of cosmeceutical effectiveness was undoubtedly better for active formulation compared with placebo.
    Prime. 07/2012; 2(5).
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    ABSTRACT: So-called 'sex-specific fat' appears to be physiologically advantageous, but it has a cosmetic downside as well. A pool of functional ingredients, principally represented by botanical extracts, was selected to treat this condition, specifically for people intimidated by other more invasive approaches. The topical product was formulated using ingredients aimed at two specific actions; adipolysis and microcirculation stimulation [1-4]. The product was conceived for night-time application because during the night the body releases Growth Hormone, which activates adipolysis and blood flow, and the skin barrier function and metabolic rate are also more active. We aimed at assessing the effect of the topical product vs. placebo through an in vivo evaluation protocol, performed using a skin bioengineering method, namely ultrasonography, and clinical evaluation. The protocol was conducted as a double-blind, active vs. placebo trial (form. N°690 vs. form. N°1362), on 100 subjects enrolled by two research centres (Pavia and Rome, Italy), over a 4 week period, during which volunteers were checked four times, both clinically and instrumentally. At the end of the trial, both centres agreed on the slimming effects of the topical product. Tolerability was good. The enrolled volunteers expressed their full satisfaction regarding the product under study.
    International journal of cosmetic science 02/2012; 34(3):263-72.
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    ABSTRACT: Export Date: 3 April 2012, Source: Scopus, Article in Press
    International Journal of Cosmetic Science 01/2012;
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    Journal of Plastic Dermatology. 01/2012; 8(3).
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    ABSTRACT: Aim of this study was to evaluate by clinical and non invasive instrumental evaluations the efficacy and the tolerance of a cosmetic slimming treatment specific for light/moder-ate adipose pannicula at level of the waist and hips. The protocol has been performed as double blind, active versus placebo trial on 110 volunteers for a period of 4 weeks. The study foresaw an addicted visit 4 weeks after the last product application. During the visit the following clinical/instrumental evaluation was carried out: clinical assessment of hip-abdomen adipose pannicula, circumference measurements, ultrasonographic evaluation of adipose pannicula thickness and plicometry. At the end of the treatment the study product slimming activity resulted clinically different than the placebo, deter-mined a significative decrease of abdomen/hips circumferences and a considerable reduction of abdomen/hips adipose pannicula thickness. The tolerability was good. The enrolled volunteers expressed their full satisfaction about the studied product.
    Journal of Plastic Dermatology. 01/2011; 7(2).