Naheed Waseem

Publications (2)0 Total impact

• Source

  Available from: pharmascope.org

  Article: Anti-inflammatory potential of alcoholic extract of Indigofera oblongifolia Forsk

  Nitinkumar Upwar, Roshan Patel, Naheed Waseem, Naveen Kumar Mahobia
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  ABSTRACT: Anti-inflammatory activity of the methanolic extracts of the root of Indigofera oblongifolia Forsk was studied in Wistar rats using the carrageenan induced left hind paw edema. The methanolic extracts at the dose of 250 mg/kg and 500 mg/kg body weight shows moderate to significant anti-inflammatory activity. The methanolic extracts of Indigofera oblongifolia Forsk reduced the edema induced by carrageenan by 32.19 % and 40.97 % respectively on oral administration of 250 mg/kg and 500 mg/kg body weight as compared to the untreated control group. Diclo-fenac sodium at 10 mg/kg body weight inhibited the edema volume by 39.02 %. The results indicated that the methanolic extract 500 mg/kg body weight shows more significant (p<0.05) anti-inflammatory activity when com-pared with the standard and untreated control.
  Int. J. Res. Pharm. Sci. International Journal of Research in Pharmaceutical Sciences. 01/2011; 2(23).
• Article: Analgesic and antipyretic activities of Momordica charantia Linn. fruits.

  Roshan Patel, Naveen Mahobia, Nitin Upwar, Naheed Waseem, Hetal Talaviya, Zalak Patel
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  ABSTRACT: Plant Momordica charantia Linn. belongs to family Cucurbitaceae. It is known as bitter gourd in English and karela in Hindi. Earlier claims show that the plant is used in stomachic ailments as a carminative tonic; as an antipyretic and antidiabetic agent; and in rheumatoid arthritis and gout. The fruit has been claimed to contain charantin, steroidal saponin, momordium, carbohydrates, mineral matters, ascorbic acid, alkaloids, glucosides, etc. The ethanolic extract of the fruit showed the presence of alkaloids, tannins, glycosides, steroids, proteins, and carbohydrates. The present study was carried out using acetic acid-induced writhing and tail-immersion tests in mice, while yeast-induced pyrexia in rats. The ethanolic extracts (250 and 500 mg/kg, po.) showed an analgesic and antipyretic effect, which was significantly higher than that in the control rats. The observed pharmacological activities provide the scientific basis to support traditional claims as well as explore some new and promising leads.
  Journal of Advanced Pharmaceutical Technology & Research 10/2010; 1(4):415-8.