Junsoo Lee

Publications (3)2.64 Total impact

• Article: Effect of grape seed oil supplementation on plasma lipid profiles in rats

  Dae-Jung Kim, Geonuk Jeon, Jeehye Sung, Sea-Kwan Oh, Ha-Cheol Hong, Junsoo Lee
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  ABSTRACT: The purpose of the study was to investigate the comparative effects of feeding of grape seed oil (GSO), soybean oil (SO), and lard on plasma lipid profile in rats. Lard fed diets increased body weight gain in rats and resulted in negative effects on lipoprotein metabolism. However, the GSO fed rats had a significant reduction in total cholesterol (TC, 60.6 mg/dL), low density lipoprotein cholesterol (LDLC, 16.8 mg/dL), and atherogenic index (AI, 0.9), and the ratio of high density lipoprotein cholesterol (HDLC) to TC (0.5) was significantly higher than those of SO and lard groups. These data suggest that GSO supplementation has significant health benefits through favorable alterations in plasma lipid profiles compared to SO and lard fed rats. GSO may be good dietary oil and may provide health benefits in hyperlipidemia and related complications. Keywordsgrape seed oil-lipid profile-rat-soybean oil-lard
  Food science and biotechnology 04/2012; 19(1):249-252. · 0.49 Impact Factor
• Article: Innate immune stimulation of polysaccharide fraction from grape peel

  Dae-Jung Kim, Junsoo Lee, Kwang-Won Yu, Taek Joon Yoon
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  ABSTRACT: The present study was performed to investigate the innate immune stimulating effects of the polysaccharide fraction (VL-3IIb) from peel of grape (Vitis labrusca). VL-3IIb treatment of peritoneal macrophage produced various cytokines (IL-6, IL-10, and IL-12) in vitro experiment. The intravenous (i.v.) administration of VL-3IIb in mice (100 μg/mouse) significantly augmented cytotoxicity of natural killer (NK) cells against Yac-1 tumor cells. The i.v. administration of VL-3IIb (50–500 μg/mouse) 2 days before tumor inoculation significantly inhibited lung metastasis of colon26-M3.1 carcinoma cells in a dose-independent manner. In addition, the depletion of NK cells by injection of rabbit anti-asialo GM1 serum abolished the inhibitory effect of VL-3IIb on lung metastasis of colon26-M3.1 cells. These results indicate that VL-3IIb has antitumor activity to inhibit tumor metastasis prophylactically, and its antitumor effect is associated with activation of macrophages and NK cells. Keywordsgrape peel–polysaccharide–innate immune response–anti-metastasis–natural killer (NK) cell
  Food science and biotechnology 04/2012; 20(1):107-113. · 0.49 Impact Factor
• Article: Black rice bran as an ingredient in noodles: chemical and functional evaluation.

  Suhyun Kong, Dae-Jung Kim, Sea-Kwan Oh, Im-Soo Choi, Heon-Sang Jeong, Junsoo Lee
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  ABSTRACT: This study examined the feasibility of using black rice bran (BRB) as an ingredient of noodles and evaluated the effect of BRB incorporation in noodles in terms of chemical and functional attributes. Noodles were prepared with BRB as an ingredient at different levels (2%, 5%, 10%, and 15%). Addition of BRB (5%, 10%, and 15%) significantly decreased the cohesiveness of noodles in texture evaluation. Noodles with different levels of BRB were functionally evaluated and content of polyphenolics, flavonoids, and anthocyanins were improved compared to the control. Additionally, antioxidant activity of BRB noodles was increased compared to the control. BRB can be an excellent ingredient to increase the nutritional value and antioxidant properties of noodles.
  Journal of Food Science 03/2012; 77(3):C303-7. · 1.66 Impact Factor