Vinicius R Fanfa

Publications (2)1.04 Total impact

• Article: Report of cryptosporidiosis in gray brocket deer (Mazama gouazoupira) in southern Brazil

  Andressa R. Reginatto, Matheus H. Farret, Vinicius R. Fanfa, Aleksandro S. Da Silva, Régis A. Zanette, Alexandre A. Tonin, Silvia G. Monteiro
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  ABSTRACT: The aim of this study was to report the occurrence of cryptosporidiosis in gray brocket deer in Brazil. Fecal samples of a male and a female Mazama gouazoupira kept in captivity in southern Brazil were evaluated. Samples collected at 10-d intervals were analyzed by the centrifugal flotation technique and stained by the modified Ziehl–Neelsen and by the Kinyoun staining methods. The first analysis showed a high number of Cryptosporidium parvum oocysts in the feces, associated with the presence of diarrhea in both animals. However, even without drug therapy, the number of oocysts of the protozoan decreased and the feces returned to normal after 10days. This is the first report of cryptosporidiosis in M. gouazoupira. KeywordsCervidae- Cryptosporidium -Diarrhea
  Comparative Clinical Pathology 04/2012; 19(5):523-525.
• Source

  Available from: Kaio Tavares

  Article: Susceptibility of mice to Trypanosoma evansi treated with human plasma containing different concentrations of apolipoprotein L-1.

  Aleksandro S Da Silva, Vinicius R Fanfa, Mateus A Otto, Lucas T Gressler, Kaio C S Tavares, Cícera R Lazzarotto, Alexandre A Tonin, Luiz C Miletti, Marta M M F Duarte, Silvia G Monteiro
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  ABSTRACT: The aim of this study was to test the susceptibility of mice to Trypanosoma evansi treated with human plasma containing different concentrations of apolipoprotein L-1 (APOL1). For this experiment, a strain of T. evansi and human plasma (plasmas 1, 2, and 3) from 3 adult males clinically healthy were used. In vivo test used 50 mice divided in 5 groups (A to E) with 10 animals in each group. Animals of groups B to E were infected, and then treated with 0.2 ml of human plasma in the following outline: negative control (A), positive control (B), treatment with plasma 1 (C), treatment with plasma 2 (D), and treatment with plasma 3 (E). Mice treated with human plasma showed an increase in longevity of 40.9 ± 0.3 (C), 20 ± 9.0 (D) and 35.6 ± 9.3 (E) days compared to the control group (B) which was 4.3 ± 0.5 days. The number of surviving mice and free of the parasite (blood smear and PCR negative) at the end of the experiment was 90%, 0%, and 60% for groups C, D, and E, respectively. The quantification of APOL1 was performed due to the large difference in the treatments that differed in the source plasma. In plasmas 1, 2, and 3 was detected the concentration of 194, 99, and 115 mg/dl of APOL1, respectively. However, we believe that this difference in the treatment efficiency is related to the level of APOL1 in plasmas.
  The Korean Journal of Parasitology 12/2011; 49(4):427-30. · 1.04 Impact Factor