[show abstract][hide abstract] ABSTRACT: The most common malignancy of the lip is squamous cell carcinoma (SCC). In our population, according to epidemiological data, almost a half of all (45%) SCC of oral mucous tissue spreads over the lower and upper lip. The aim of this study was to estimate prognostic importance of histopathologic characteristics--histologic grade, nuclear grade and tumor size in relation to the appearance of lymph node metastases and relapse in SCC of the lip.
In the retrospective-prospective study 70 cases of lower and upper lip SCC were analyzed. They were diagnosed from 2002 to 2006 in the Clinic of Maxillofacial Surgery, Clinical Center of Montenegro. The data about localization of the carcinomas, histopathologic characteristics and lymph node status were taken from medical files of the patients. The patients were followed up in a 3-year period and the disease relapse or/and metastatic disease appearance were registereds.
There was statistically significant difference in tumor size among the patients with and without disease relapse (p = 0.027). Logistic regression analysis showed that the tumor size is a statistically significant factor (R = 0.186; p = 0.011) for the appearance of regional lymph node metastases. Relative risk [exp (B)] for the appearance of regional lymph node metastases in relation to tumor size was 2.807.
Histologic and nuclear grade of lip SCC are not prognostic factors for the appearance of the disease relapse and regional lymph node metastases. Tumor size is a predictive factor of the relapse appearance, as well as for lymph node metastases appearance. In clinical practice, tumor size is a factor that classifies patients with lip SCC into the groups of higher and smaller risk of relapse appearance and for lymph node metastases appearance. Our results suggest that, risk for lymph node metastases appearance increases 2.8 times with increasing of the tumor size over 2 cm in diameter.
[show abstract][hide abstract] ABSTRACT: This paper describes the development of a variety of classical biomedical experimental exercises by using interdisciplinary
approach. A number of them have been developed integrating the knowledge of sensors, electronics, microprocessors and MATLAB
software. The exercises depicted here are intended to introduce students to fundamental concepts of biomedical instrumentation,
from the sensing requirements to subsequent data analyze. This not only enhances the fundamental knowledge, but also trains
students in the application of complex concepts in real-world of practice and laboratory research. The emphasis is put on
the measurement of physiological vital parameters. Similar concept can be applied to some other signals and systems, as well.
Using proposed approach sophisticated and expensive equipment can be replaced successfully by a functional low cost hardware
and/or versatile virtual instruments.
KeywordsBME education-physiological measurements-teaching tool-ECG-PPG-MATLAB-virtual instrument
[show abstract][hide abstract] ABSTRACT: Epidural hematoma of the posterior cranial fossa (EHPCF) is a rare complication in head injuries. Furthermore, nonspecific clinical signs and the rare occurrence of this lesion in craniocerebral injuries make the establishment of a diagnosis more difficult. The aim of the paper is to point to the advantages of early diagnosis. During the 1982-2008 period, 18 patients with EHPCF were operated on at University Department of Neurosurgery, Clinical Center of Montenegro in Podgorica. The clinical picture, neuroradiological examination findings and outcome of operated patients were retrospectively analyzed. In our patient series, EHPCF accounted for 0.11% of craniocerebral injuries or 7.9% of epidural hematomas recorded. In 11 cases, the injury was inflicted in traffic accidents and in 7 patients it was caused by fall. Linear fracture of the occipital bone was detected by radiographic investigation in 12, isolated diastasis fracture of lambdoid suture in four, and linear fracture of the occipital bone with diastasis fracture of lambdoid suture in two patients. Glasgow Coma Scale of 8 and less was present in three, 9-12 in seven, and 13-15 in eight patients. The majority of cases (90%) were detected within 24 hours. In all cases, the diagnosis was made by computed tomography. Mortality rate was 11.11%. Early computed tomography of the head in combination with clinical picture and timely surgical intervention could reduce the mortality and morbidity in these lesions.
[show abstract][hide abstract] ABSTRACT: e-Health has clearly started to become an important issue for implementation, operational deployment of services and a promising market for industry. The need for concentration of the information society technologies on the future so-called convergence generation has been specifically noted since FP6. The scope of this paper is to present an ambient, home based health and wellness measurement and monitoring architecture, especially targeting the elderly and chronic patients, aiming to facilitate their social inclusion (e-inclusion) by providing the means of easy follow-up from their home environment. The proposed paper presents a one-button functional, wireless monitoring system capable of acquiring 3 leads of ECG, pulse oxymetry and temperature measurements, and transmitting them over ZigBee to a computing device, which in turn is responsible for the transmission of the signal to a consultation unit. The authors envisage the development of a lightweight unobtrusive, belt-like wearable device that would enable patients to be monitored daily and at the same time allow them to perform their regular daily activities.
Proceedings of the 1st ACM International Conference on Pervasive Technologies Related to Assistive Environments, PETRA 2008, Athens, Greece, July 16-18, 2008; 01/2008