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ABSTRACT: The resistance of Aedes aegypti mosquitoes to insecticides threatens
dengue virus control efforts. In this study, Ae. aegypti larvae collected from 12
subdistricts in Surabaya, Indonesia, where dengue is endemic, were tested for
resistance to the organophosphate, temephos. Susceptibility testing, performed
according to World Health Organization (WHO) methods, showed all field strains
were resistant to temephos at a dose of 0.012 mg/l, with mortality rates at 24 hours
of 22% to 60%. Another susceptibility test to determine median lethal time (LT50)
indicates resistance ratios ranging from 2.2 to 8.5. Although incipient resistance
was detected at a dosage of 1 mg/l, as determined by the LT50, mortalities higher
than 80% within 24 hours were detected using the WHO method in nine subdistricts
of Surabaya, indicating temephos at 1 mg/l is still effective in field conditions
in these areas. In three subdistricts (Tambaksari, Gubeng and Sawahan),
the mortality rates were under 80%, indicating possible resistance to temephos.
The Southeast Asian journal of tropical medicine and public health 01/2012; 43(1):29. · 0.60 Impact Factor