Yi Li

Publications (3)9.54 Total impact

• Article: High blood pressure in Chinese ethnic minorities: report from rural Yunnan province.

  Steven Yang, Sandy Liu, Ying Wang, Hao Wan, Dong Zhao, Yi Li, Shan Shan Chen, Yangfeng Wu, Laurie Dustin, Stan Azen, Da Yi Hu, Robert C Detrano
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  ABSTRACT: Hypertension (HTN) is a growing cause of morbidity and mortality among rural Chinese. While HTN has been studied in various regions of China, little is known about HTN among ethnic minorities in rural China. A total of 36 villages were randomly selected from Yunnan province, China. From these villages, a total of 1,676 subjects from 10 ethnic minorities and the Han ethnic majority were selected for interview and blood pressure (BP) measurement. From each village, 50-80 men and women between the ages of 50 and 70 years were randomly selected. HTN prevalence, treatment, and control rates of HTN were evaluated in these 11 ethnic groups. After controlling for age, gender, body mass index (BMI), smoking, alcohol, and monosodium glutamate intake, prevalence of HTN varied between 25% in the Hani minority and 64% in the Tibetan minority (P < 0.001). Treatment rates varied between 0% in the Hani minority and 41% in the Tibetan minority (P = 0.006). Control rates varied between 0% in the Hani minority and 17% in the Tibetan minority (P = 0.28). Prevalence, treatment, and control rates in the Han ethnic group were 35, 22, and 12%, respectively. The prevalence of HTN varies widely among China's ethnic groups. Treatment and control rates of HTN also vary and are inadequate in the minority ethnic groups as well as in the Han majority.
  American Journal of Hypertension 08/2011; 24(11):1209-14. · 3.18 Impact Factor
• Article: The farther from town the lower the blood pressure: report from rural Yunnan province.

  Jie Huang, Jinming Yu, Dayi Hu, Yangfeng Wu, Jingqian Lu, Yi Li, Ying Huang, Stanley P Azen, Laurie D Dustin, Robert C Detrano
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  ABSTRACT: Hypertension (HTN) is a major cause of death in Chinese farmers. Remoteness from population centers may independently affect HTN prevalence and severity. We used random cluster sampling to select 27 villages in Yunnan province, China. Within each village, we randomly selected 50-80 men and women between the ages of 50 and 70 years. A total of 1,177 participants underwent interviews and blood pressure (BP) measurement. We evaluated the relationship between BP and distance of the participants' village from the town and county centers with and without adjustment for covariates. There was a significant (P < 0.001) inverse relationship between BP and distance from populations centers. For every 10 km from the town center, the mean systolic BP (SBP) in the village decreased by 1.2 mm Hg and the mean diastolic by 0.5 mm Hg. After adjustment for age, gender, ethnicity, body mass index, smoking, and drinking, we found that SBP decreased by 1.8 mm Hg (P = 0.03) and diastolic BP by 1.0 mm Hg (P = 0.02) for every 10 km distance from the town center. HTN prevalence and severity are significantly linked to distance from population centers in rural Chinese farmers. The farther a farmer's village is from larger population centers, the greater is the probability that his/her BP will be normal. This relationship is independent of age, gender, ethnicity, body mass index, smoking, and alcohol use. Strategies in addressing HTN in rural regions should take account of this geographic dependence on distance from population centers.
  American Journal of Hypertension 03/2011; 24(3):335-9. · 3.18 Impact Factor
• Article: Association of blood pressure with left ventricular mass in untreated hypertensives in rural Yunnan Province.

  Ashkan Akasheh, Yangfeng Wu, Yi Li, Laurie D Dustin, Nathan D Wong, Julius M Gardin, Stanley P Azen, Robert C Detrano
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  ABSTRACT: Chinese rural residents make up one-eighth of the world's population. Hypertension (HTN) and its resultant cardiovascular complications are rapidly increasing in this vast segment of humanity, while its treatment and control remain unacceptably low. HTN is associated with increased left ventricular mass (LVM), but the magnitude and characteristics of this relationship in persons not undergoing treatment are unknown. We studied 344 randomly selected adults who were not being treated for HTN and who had ages between 50 and 70 years (mean age 57.8, 51.7% female) using a questionnaire, height, weight, blood pressure (BP), and ultrasonic measurements of LVM. We performed bivariate and multivariable regression analysis to examine the relation of BP with LVM index (LVMI). We found a HTN prevalence of 30%. There was a significant (P < 0.0001) linear relationship between BP and LVMI in this untreated population. Diastolic (DBP) compared to systolic BP (SBP) was more strongly associated with LVMI (beta = 0.714 vs. 0.379, both P = 0.02). Persons with vs. without HTN had higher LVMI (102.5 g vs. 84.9 g, P < 0.0001). The LVMI of hypertensives, not undergoing treatment in rural Yunnan province is strongly related to BP, especially DBP.
  American Journal of Hypertension 05/2009; 22(7):730-4. · 3.18 Impact Factor