International Journal of Gynecology & Obstetrics 02/2006; 92(1):81-2. DOI:10.1016/j.ijgo.2005.07.018 · 1.54 Impact Factor
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ABSTRACT: This study was designed to correlate fetuses in a normal prenatal population who exhibited transient nuchal translucency (NT) with both prenatal course and pregnancy outcome.
The fetuses with abnormal NT were followed by ultrasonography at 1-2-week intervals during their prenatal course. Fetuses with NT who exhibited no detectable congenital malformations were defined as the NTO group; fetuses with abnormal NT and structural malformations but no chromosomal abnormalities were placed in the SM group; and fetuses with abnormal NT, structural malformations, and chromosomal abnormalities were categorized as the CA group. The groups were compared by: maternal age, weeks of gestation by ultrasound and the NT value at the initial exam, the maximum NT value, and the duration of abnormal NT.
During the study period, 92 fetuses with abnormal NT were found, monochorionic twins excluded. Of the 92 fetuses, 80 were in the NTO group, 10 were in the SM group, and two were in the CA group. The maternal age and the gestational weeks at the initial diagnosis were not significantly different in the NTO and the SM groups. However, the NT value at the initial diagnosis, maximum NT value, and the duration of abnormal NT were significantly greater in the SM group than those values in the NTO group.
Fetuses with transient nuchal translucency commonly had structural malformations, particularly fetuses with significant and large persistent NT.
International Journal of Gynecology & Obstetrics 01/2003; 79(3):225-8. DOI:10.1016/S0020-7292(02)00251-5 · 1.54 Impact Factor
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ABSTRACT: To compare the intensity of stress responses caused by laparoscopy combined with CO2 insufflation (CI) with those caused by mechanical elevation of the abdominal wall (MEA).
Prospective study (Canadian Task Force classification I).
Tertiary care university hospital.
Thirty-one women. Intervention. Laparoscopy, 16 with CI and 15 with MEA.
Circulating levels of norepinephrine, epinephrine, cortisol, and interleukin (IL)-6 were compared in the two groups. Arterial partial pressure of CO2 (PaCO2) did not increase during laparoscopy by either method. Plasma norepinephrine and epinephrine levels increased after extubation in the MEA group but not in the CI group. Circulating cortisol levels in both groups increased during laparoscopy; mean intraoperative levels were higher in the CI group. Serum IL-6 levels increased after extubation in the MEA but not the CI group. Mean heart rate increased during laparoscopy in both groups, whereas blood pressure increased only in the CI group. More patients in the MEA group required postoperative analgesia.
Laparoscopy with MEA caused more pronounced adrenosympathetic and cytokine responses than that with CI when PaCO2 was maintained within the range of normocapnia.
The Journal of the American Association of Gynecologic Laparoscopists 09/2000; 7(3):363-71. DOI:10.1016/S1074-3804(05)60480-X · 1.61 Impact Factor