Y J Lee

Ewha Womans University, Sŏul, Seoul, South Korea

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Publications (269)507.12 Total impact

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    ABSTRACT: Scedosporium spp. is the most common mold infection in pneumonia resulting from near-drowning. Three fatal scedosporiosis cases developed after solid organ transplantation, probably transmitted from the nearly-drowned donor. One heart transplant recipient and two kidney transplant recipients developed fatal scedosporiosis following deceased donor transplantation from the same donor, a nearly-drowned victim of a suicide attempt. Genotypically, indistinguishable strains of Scedosporium auratiacum were recovered from the three recipients. Two liver transplant recipients from the same donor received prophylactic voriconazole without any subsequent signs of infection. To determine the safety of donation from nearly-drowned donors, a national traceback investigation was also performed of the causes of deaths in all transplant recipients who received organs from drowned donors between 2001 and 2013. Over 13 years, 2600 deceased donor transplants were performed in Korea. Among these 2600 deceased donor transplants, 27 (1%) victims of drowning donated their organs. From these 27 donors, 84 patients received organ transplants and 18 died, including the above three. We found no microbiologic evidence of invasive mold transmission from the nearly-drowned donors to the other 15 recipients. Although disseminated infection in the donor could not be demonstrated by culture, undiagnosed disseminated donor infection and transmission of Scedosporium spp. should be considered in near-drowning events.
    American Journal of Transplantation 01/2015; DOI:10.1111/ajt.13008 · 6.19 Impact Factor
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    ABSTRACT: The ratio between the prompt ψ(2S) and J/ψ yields, reconstructed via their decays into μ^+μ^-, is measured in Pb-Pb and p-p collisions at sqrt[s_NN]=2.76 TeV. The analysis is based on Pb-Pb and p-p data samples collected by CMS at the Large Hadron Collider, corresponding to integrated luminosities of 150 μb^-1 and 5.4 pb^-1, respectively. The double ratio of measured yields (N_ψ(2S)/N_J/ψ)_Pb-Pb/(N_ψ(2S)/N_J/ψ)_p-p is computed in three Pb-Pb collision centrality bins and two kinematic ranges: one at midrapidity, |y|<1.6, covering the transverse momentum range 6.5<p_T<30 GeV/c, and the other at forward rapidity, 1.6<|y|<2.4, extending to lower p_T values, 3<p_T<30 GeV/c. The centrality-integrated double ratio changes from 0.45±0.13(stat)±0.07(syst) in the first range to 1.67±0.34(stat)±0.27(syst) in the second. This difference is most pronounced in the most central collisions.
    Physical Review Letters 12/2014; 113(26):262301. · 7.73 Impact Factor
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    ABSTRACT: Background Reactive oxygen species (ROS) contribute to the cell dysfunction and tissue damage that result from glucolipotoxicity in diabetes. ROS formation in cells causes oxidative stress, thereby activating oxidative damage-inducing genes. Nuclear factor erythroid 2-related factor 2 (Nrf2) has been shown to play an essential role in the vital defence mechanisms that help cells cope with oxidative stress.AimTo compare Nrf2 protein expression in nondiabetic skin tissue with that in diabetic skin tissue.Methods Nrf2 expression was evaluated by Western blotting, reverse transcription (RT)-PCR, and immunohistochemical staining in diabetic and nondiabetic skin tissues. Dinitrophenylhydrazone derivatives of protein carbonyls in the oxidized proteins were measured by oxyblotting analysis. Cytoplasmic and nuclear Nrf2 protein expression was determined to identify the activity and level of Nrf2.ResultsProtein oxidation, a marker of oxidative stress, was found to be increased in diabetic skin tissue. In subcellular fraction analysis, Nrf2 protein was detected in the nuclei and cytoplasm of nondiabetic skin tissues, and the Nrf2 protein band was identified from among the multiple bands detected, using small interfering RNA-mediated Nrf2 gene silencing. Compared with nondiabetic tissue, diabetic skin tissue showed simultaneous downregulation of Nrf2 at both the mRNA and protein levels. Nuclear condensation, loss of nuclei, and vacuolization were seen in some parts of the specimen by haematoxylin and eosin staining of diabetic skin tissue. Immunohistochemical staining of Nrf2 confirmed the RT-PCR and Western blotting results.Conclusions Collectively, our data show that expression of Nrf2 is clearly downregulated in diabetic skin tissue, and suggest that Nrf2 may be necessary for protection against glucose-induced oxidative stress.
    Clinical and Experimental Dermatology 12/2014; 40(2). DOI:10.1111/ced.12487 · 1.23 Impact Factor
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    ABSTRACT: This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C.
    European Physical Journal C 11/2014; DOI:10.1140/epjc/s10052-014-3026-9 · 5.44 Impact Factor
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    ABSTRACT: A joint measurement is presented of the branching fractions $B^0_s\to\mu^+\mu^-$ and $B^0\to\mu^+\mu^-$ in proton-proton collisions at the LHC by the CMS and LHCb experiments. The data samples were collected in 2011 at a centre-of-mass energy of 7 TeV, and in 2012 at 8 TeV. The combined analysis produces the first observation of the $B^0_s\to\mu^+\mu^-$ decay, with a statistical significance exceeding six standard deviations, and the best measurement of its branching fraction so far, and three standard deviation evidence for the $B^0\to\mu^+\mu^-$ decay. The measurements are statistically compatible with SM predictions and impose stringent constraints on several theories beyond the SM.
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    ABSTRACT: After a contract with Hyundai Heavy Industries Co. Ltd. (HHI) on January 2010 for the manufacture of the ITER equatorial and lower ports, manufacturing preparation activities have been performed. As part of the preparation activities, a full scale mock-up of the lower port stub extension (LPSE) #16 was fabricated by HHI in order to verify fabrication feasibility and set up the fabrication sequence for the LPSE. In this paper, major technical results from fabrication of a full scale mock-up will be presented with emphasis on the main manufacturing procedure, welding, nondestructive examination (NDE) and 3D dimensional inspection. Afterwards, progress of real product manufacturing is introduced.
    Fusion Engineering and Design 10/2014; DOI:10.1016/j.fusengdes.2014.04.053 · 1.15 Impact Factor
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    ABSTRACT: The production of jets associated to bottom quarks is measured for the first time in PbPb collisions at a center-of-mass energy of 2.76 TeV per nucleon pair. Jet spectra are reported in the transverse momentum (p_{T}) range of 80-250 GeV/c, and within pseudorapidity |η|<2. The nuclear modification factor (R_{AA}) calculated from these spectra shows a strong suppression in the b-jet yield in PbPb collisions relative to the yield observed in pp collisions at the same energy. The suppression persists to the largest values of p_{T} studied, and is centrality dependent. The R_{AA} is about 0.4 in the most central events, similar to previous observations for inclusive jets. This implies that jet quenching does not have a strong dependence on parton mass and flavor in the jet p_{T} range studied.
    Physical Review Letters 09/2014; 113(13):132301. · 7.73 Impact Factor
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    ABSTRACT: Objectives: Transoral laser microsurgery is considered one of the best techniques for the treatment of early stage glottic cancer. But voice outcome and quality of life (QOL) after laser cordectomy has not been fully evaluated. The aim of this study is to evaluate the voice outcome and QOL after transoral laser cordectomy in glottic cancer.
    Otolaryngology Head and Neck Surgery 09/2014; 151(1 Suppl):P194-P194. DOI:10.1177/0194599814541629a178 · 1.72 Impact Factor
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    ABSTRACT: Objectives: Burning mouth syndrome (BMS) is characterized as a burning sensation in the mouth without definite oral pathology. Although BMS is not uncommon, the etiology and psychological profiles are not well established. The aim of this study is to evaluate the role of psychological factors in BMS patients.
    Otolaryngology Head and Neck Surgery 09/2014; 151(1 Suppl):P154-P154. DOI:10.1177/0194599814541629a54 · 1.72 Impact Factor
  • Fertility and Sterility 09/2014; 102(3):e315. DOI:10.1016/j.fertnstert.2014.07.1067 · 4.30 Impact Factor
  • Advances in Applied Ceramics 08/2014; 113(6):341-345. DOI:10.1179/1743676114Y.0000000167 · 1.11 Impact Factor
  • Advances in Applied Ceramics 08/2014; 113(6):352-357. DOI:10.1179/1743676114Y.0000000171 · 1.11 Impact Factor
  • Y.‐J. Lee, M. S. Kim, S. Cho, S. R. Kim
    International Journal of Clinical Practice 05/2014; 68(5). DOI:10.1111/ijcp.12423 · 2.54 Impact Factor
  • S.J. Cho, Y.J. Lee, Y.H. Kim, J.Y. Koo
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    ABSTRACT: HVDC transformers are one of the main components for long distance transmission, for which many investigations have been done all over the world in order to increase their efficiency and reliability. Regarding their insulation, oil immersed pressboards are widely used, representing one of the most important elements playing a role in transformer behaviors. Under DC operation, space charges accumulating between the oil and pressboard have been reported as the influential cause possibly giving rise to unexpected service failures under the transient voltage from the grid. However, it might be possible to presume that the accumulation of space charge could be facilitated inside the multilayered pressboard causing insulation breakdown in a different way. In addition, other parameters could be potential issues to investigate: non homogeneous temperature distribution along the oil circulation path and the DC field intensity. The former could explain the conductivity variation causing the non-uniform DC field distribution, while the latter plays a role in the variation of conductivity. With these in mind, three parameters have mainly been put under experimental investigation. For this purpose, a DC voltage is applied to the oil immersed pressboard, and then the polarization and leakage current are measured and analyzed. The mobility of the space charge is calculated from the former as a function of the number of layers, while the conductivity is obtained from the latter.
    IEEE Transactions on Dielectrics and Electrical Insulation 04/2014; 21(2):866-872. DOI:10.1109/TDEI.2013.003957 · 1.23 Impact Factor
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    ABSTRACT: InGaAs-capped InAs quantum dots (QDs) and InAs QDs were adopted for the study of the effects through growth temperature and the band structure of InAs QDs on the performance of GaAs-based QD solar cell. It has been shown that the defects due to low temperature growth resulted in the decrease of Voc, Jsc and external quantum efficiency for GaAs bulk solar cell and QD embedded solar cells. It has been also found that InAs QDs act as defects by trapping photo-generated carries which affect the carrier transport in QD solar cell. The QD solar cell with InGaAs-capped InAs QDs showed higher performance than the QD solar cell with only InAs QDs. Such result has been explained by photo-generated carrier trapping and tunneling through InGaAs QW state in InGaAs-capped InAs QDs.
    Journal of Nanoscience and Nanotechnology 04/2014; 14(4):2955-9. DOI:10.1166/jnn.2014.8639 · 1.34 Impact Factor
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    ABSTRACT: This study was conducted to compare the expression patterns of serum alpha-fetoprotein (AFP) and proteins induced by vitamin K absence or antagonist-II (PIVKA-II) in hepatocellular carcinoma (HCC) patients undergoing liver transplantation (LT) and resection at a high-volume single institution. First, 663 liver transplant recipients with HCC were selected. They were divided into hepatitis B virus (HBV) (n = 628) and hepatitis C virus (HCV) groups (n = 35). Their medical records were retrospectively reviewed. Second, another cohort of 2709 patients who underwent HCC resection included 2258 HBV, 143 HCV, and 308 non-HBV non-HCV (NBNC) patients. In the transplantation group, pretransplantation AFP level >20 ng/mL was observed in 42.5% of HBV patients and 60% of HCV patients (P = .042). PIVKA-II level >40 mAU/mL was observed in 30.6% of HBV patients and 42.9% of HCV patients (P = .127). In the resection group, a preoperative AFP level >20 ng/mL was observed in 51.7% of HBV patients and 43.3% of HCV patients (P = .052). PIVKA-II level >40 mAU/mL was observed in 59.7% of HBV patients and 56.6% of HCV patients (P = .47). Preoperative AFP level >20 ng/mL and PIVKA-II level >40 mAU/mL were observed in 35.7% and 61% of NBNC patients, respectively. Receiver-operator characteristic curve analyses revealed that the expression pattern of PIVKA-II in patients with elevated AFP level was not predictable and vice versa, regardless of background liver diseases. This study indicates that serum AFP and PIVKA-II may be expressed variably regardless of the types of background liver disease. Further large-volume multicenter studies are needed to evaluate the possibility of the etiology-dependent expression of tumor markers.
    Transplantation Proceedings 04/2014; 46(3):888-93. DOI:10.1016/j.transproceed.2013.12.037 · 0.95 Impact Factor
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    ABSTRACT: High density (In)GaAs/GaAs/AIGaAs nanowires (NWs) consisting of n-type core and p-type shell have been vertically grown on (111) GaAs substrate using metal organic chemical vapor deposition (MOCVD) and fabricated into solar cells. Au colloidal nanoparticles (NPs) are employed as a catalyst. High density nanowires were obtained by uniform distribution of Au NPs. Fe-SEM, TEM and HRTEM images show that the morphology of shell is sensitive to p-doping concentration. Increase in the density of p-doping precursor results in "kinking" of NPs and rough shell surface. The origin of kinking has been explained by the GaAs twin phases due to Zn segregation on the surface of shell. It has been observed that the morphology of NPs can be controlled through optimizing various source purge technique of DEZn and deposition temperature. Electrical properties of core-shell doped NWs are carried out using I-V characterization. The core-shell NWs show characteristics of p-n junction as revealed by I-V studies.
    Journal of Nanoscience and Nanotechnology 04/2014; 14(4):2913-8. DOI:10.1166/jnn.2014.8606 · 1.34 Impact Factor
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    ABSTRACT: Nanometer scale thin InAs layer has been incorporated between Si (100) substrate and GaAs/Al0.3Ga0.7As multiple quantum well (MQW) nanostructure in order to reduce the defects generation during the growth of GaAs buffer layer on Si substrate. Observations based on atomic force microscopy (AFM) and transmission electron microscopy (TEM) suggest that initiation and propagation of defect at the Si/GaAs interface could be suppressed by incorporating thin (1 nm in thickness) InAs layer. Consequently, the microstructure and resulting optical properties improved as compared to the MQW structure formed directly on Si substrate without the InAs layer. It was also observed that there exists some limit to the desirable thickness of the InAs layer since the MQW structure having thicker InAs layer (4 nm-thick) showed deteriorated properties.
    Journal of Nanoscience and Nanotechnology 04/2014; 14(4):2984-9. DOI:10.1166/jnn.2014.8593 · 1.34 Impact Factor
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    G.H. Lee, Y.J. Lee, J.H. Cho, M.N. Kim
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    ABSTRACT: Voice activity detection is very important process that find voice activity from noisy speech signal for noise cancelling and speech enhancement. Over the past few years, many studies have been made on voice activity detection, it has poor performance for speech signal of sentence form in a low SNR environment. In this paper, it proposed new voice activity detection algorithm that has beginning VAD process using entropy and main VAD process using fuzzy membership shifted c-means clustering. We conduct an experiment in various SNR environment of white noise to evaluate performance of the proposed algorithm and confirmed good performance of the proposed algorithm.
    03/2014; 17(3). DOI:10.9717/kmms.2014.17.3.312
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    ABSTRACT: In this paper, we develop pixels with concentric-photogates for applications in time-of-flight 3-D image sensors with single-tap architecture. The pixel uses a buried-channel device and features a reduced effective electron transit length, for the rapid transfer of a signal electron. A reduction in the interpixel irregularity of signal levels and a consequent increase in the demodulation signal amplitude are observed in the single-tap operation mode as opposed to the multitap operation mode. Specifically, we are able to achieve a demodulation contrast higher than 50% from 20 MHz modulation of an 850 nm light-emitting diode illumination. Finally, we construct a sensor composed of 198 x 108 concentric photogate pixels, each with a pitch of 28 μm, and use it to generate a 3-D image conveying gross distance information and detailed object features with a distance error of less than 1% over a range of 1 to 7 m.
    IEEE Transactions on Electron Devices 02/2014; PP(99):1-1. DOI:10.1109/TED.2014.2301875 · 2.36 Impact Factor

Publication Stats

2k Citations
507.12 Total Impact Points

Institutions

  • 2015
    • Ewha Womans University
      Sŏul, Seoul, South Korea
  • 2014
    • Dong-Eui University
      • Department of Information and Communication Engineering
      Tsau-liang-hai, Busan, South Korea
    • Sungkyunkwan University
      Sŏul, Seoul, South Korea
  • 2009–2014
    • National Fusion Research Institute
      Daiden, Daejeon, South Korea
    • Hanyang University
      • • Department of Electronic and Electrical Engineering
      • • College of Medicine
      Sŏul, Seoul, South Korea
    • Kyungpook National University
      Daikyū, Daegu, South Korea
    • Hanyang University Medical Center
      Sŏul, Seoul, South Korea
  • 2005–2014
    • Chungnam National University
      • • Graduate School of Green Energy Technology
      • • College of Agriculture and Life Sciences
      Daiden, Daejeon, South Korea
  • 1996–2014
    • University of Ulsan
      • • Department of Surgery
      • • Department of Pediatrics
      Urusan, Ulsan, South Korea
  • 2013
    • Inha University
      • Department of Family Medicine
      Chemulpo, Incheon, South Korea
  • 2012–2013
    • Konkuk University
      • Department of Electronics Engineering
      Sŏul, Seoul, South Korea
    • Eulji University
      • Department of Internal Medicine
      Daiden, Daejeon, South Korea
    • Vrije Universiteit Brussel
      Bruxelles, Brussels Capital Region, Belgium
  • 2007–2013
    • Kwangwoon University
      • Department of Electronic Engineering
      Sŏul, Seoul, South Korea
  • 2000–2013
    • Ulsan University Hospital
      Urusan, Ulsan, South Korea
  • 2011
    • Asan Medical Center
      • Division of Liver Transplantation and Hepato-Biliary Surgery
      Sŏul, Seoul, South Korea
    • Soonchunhyang University
      • College of Medicine
      Onyang, South Chungcheong, South Korea
  • 2001–2011
    • Ajou University
      Sŏul, Seoul, South Korea
  • 1999–2011
    • Yonsei University Hospital
      • Department of Internal Medicine
      Sŏul, Seoul, South Korea
  • 2010
    • Yonsei University
      • Department of Pharmacology
      Seoul, Seoul, South Korea
  • 2001–2010
    • National Veterinary Research Quarantine Service
      Sŏul, Seoul, South Korea
  • 2008
    • Seoul Metropolitan Children's Hospital
      Sŏul, Seoul, South Korea
    • Korea University
      • College of Life Sciences
      Sŏul, Seoul, South Korea
  • 2005–2008
    • Catholic University of Korea
      • • Department of Radiology
      • • College of Medicine
      Sŏul, Seoul, South Korea
  • 2004–2007
    • Gwangju Institute of Science and Technology
      • School of Materials Science and Engineering
      Gwangju, Gwangju, South Korea
    • Korea Basic Science Institute KBSI
      Sŏul, Seoul, South Korea
  • 2006
    • Chungbuk National University
      • Department of Animal Sciences
      Chinsen, Chungcheongbuk-do, South Korea
  • 2002–2003
    • Korea Research Institute of Standards and Science
      Daiden, Daejeon, South Korea
  • 2001–2003
    • Cheju Halla University
      Tse-tsiu, Jeju, South Korea
  • 1997–2003
    • Seoul National University
      • • Department of Nuclear Medicine
      • • College of Pharmacy
      Sŏul, Seoul, South Korea
  • 1998
    • Kagoshima University
      Kagosima, Kagoshima, Japan