V G Rumiantsev

Publications (13)0 Total impact

• Article: [Difficulties of differential diagnostics of inflammatory intestinal diseases].

  V G Rumiantsev, L I Efremov, V N Drosdov, E N Baryshnikov, K P Neĭman
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2007;
• Article: [Diverticular disease of the colon: literature review].

  V G Rumiantsev, V A Osina, S V Levchenko
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2007;
• Article: [Nitric oxide as an inflammation marker at non-specific ulcerous colitis and Crohn's disease].

  L B Lazebnik, E N Baryshnikov, V N Drozdov, V G Rumiantsev, T V Nilova
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2006;
• Article: [Ulcerous colitis and Crohn's disease in members of one family: case description and review of literature].

  K P Neĭman, V G Rumiantsev
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2006;
• Article: [Medical and economic substantiation of the colorectal cancer screening].

  L B Lazebnik, V G Rumiantsev, Iu A Erofeeva
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2005;
• Article: [Role of short-chain fatty acids in the pathogenesis and therapy of ulcerative colitis].

  T A Kosacheva, V G Rumiantsev
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2005;
• Article: [Clinical-functional and morphological changes in the large intestine in patients with chronic abdominal ischemia].

  I A Shashkova, L A Zvenigorodskaia, S G Khomeriki, B Z Chikunova, V G Rumiantsev, A S Toporkov, V M Savrasov, V A Rogozina
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  ABSTRACT: The article presents a study of clinical variants of ischemic lesions of the large intestine (ILLI) in patients with the chronic abdominal ischemia (CAI) syndrome. There was an examination of 42 patients with putative ILLI, who had a cardiovascular pathology at the background, which led to significant hemodynamic disorders of the blood flow in unpaired visceral branches of the abdominal aorta. The authors performed a complex diagnostics of ILLI including anamnestic and clinical data, laboratory and morphological assessment of the large intestine and vessels providing its blood supply. Based on the data collected, other functional and organic diseases of the large intestine (LI) were excluded. It was revealed that the final result of ILLI differed depending on the ischemia degree--from reversible functional disorders to high-grade organic lesions of the LI. Each clinical variant of ILLI has its own clinical manifestations as well as functional, organic and morphological peculiarities of changes in the LI revealed by a laboratory and histological examination of the LI.
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2004;
• Article: [Immunosuppressive therapy of inflammatory diseases of the large intestine].

  V G Rumiantsev, V A Rogozina, V A Osina
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  ABSTRACT: The treatment of ulcerous colitis and Crohn's disease is based on suppression of various components of the immunoinflammatory cascade. In addition to aminosalicylates and glucocorticoids, drugs of primary immunosuppressive action are used for this purpose, which are adopted from clinical oncology and transplantation medicine: azathioprine, 6-mercaptopurine, methotrexate, cyclosporine A, tacrolimus, mycophenolate mofetil, thalidomide. Some of them are used for remission induction in case of hormonal dependence or resistance, while others are applied for its maintenance or at various stages of the inflammatory process course. The presented review discloses problems of clinical pharmacology of immunosuppressive drugs, side effects, results of pilot and clinical studies of ulcerous colitis and Crohn's disease. All this makes it possible to determine their role in the therapy of inflammatory diseases of the bowels.
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2004;
• Article: [Ways of reducing oncological morbidity in gastroenterology and mortality from cancer of the digestive organs].

  L B Lazebnik, S G Khomeriki, L Iu Il'chenko, V G Rumiantsev
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2003;
• Article: [Comparative efficacy of mezakol and sulfasalazine in treating chronic relapsing ulcerative colitis].

  V A Rogozina, V G Rumiantsev
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  ABSTRACT: This research testifies to the fact that it is more preferable to use mesacol than sulfasalazine in treatment of common forms of ulcerative colitis of light and average severity. Mesacol acts faster in arresting inflammations in proximal parts of the larger intestine. One can assume that the pH-dependent release of 5-aminosalicylic acid in these forms of the disease suffers less than the destruction of the diazo link by the anaerobic microflora, due to which a higher concentration of the preparation is formed in the large intestine. Another alternative explanation can be the dose-dependent effect. Thus, 2.4. g of mesacol correspond to 6 g of sulfasalazine. The dose of sulfasalazine was smaller in our study. Mesacol had no advantages over sulfasalazine in treatment of distal colitis, which can and must be treated with rectal introduction of corticosteroids and 5-aminosalicylic acid preparations. Thus, mesacol must be reserved for treatment of patients with common ulcerative colitis of light and average severity in case of intolerance to sulfasalazine or impossibility to increase the preparation dose over 4 g/day. Its efficiency and price make the preparation available for most patients and patient care institutions.
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2003;
• Article: [Disorders of hemostasis in clinical picture and pathogenesis of inflammatory diseases of the colon (literature review)].

  V G Rumiantsev, V A Rogozina, E K Golubeva, V A Osina, T A Kosacheva
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  ABSTRACT: Hemostatic disorders are involved in the pathogenesis of inflammatory large intestine diseases. Both thrombocytes and humoral coagulation factors are involved in this process. An attempt to correct these disorders will allow not only to declare a new approach to the treatment of inflammatory large intestine diseases but also to clarify their role in the occurrence and persistence of an active inflammation during these diseases.
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2002;
• Article: [Crohn's disease in children].

  V G Rumiantsev, N E Shchigoleva
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  ABSTRACT: Crohn's disease is a chronic transmural inflammation that can involve any part of the digestive system, from the oral cavity to the anal canal, being combined with many abenteric manifestations. It can appear at any age. The first description of this disease in a teenager was made in 1834 by B.B. Crohn, and 11 years later a series of observations describing 48 children with this disease was published. The concept of the Crohn's disease as a non-children illness underwent a change with the widening of diagnostic possibilities, wide use of the endoscopic method of diagnostics in pediatric practice, and histological studies of biopsy materials. A steady growth of the frequency of Crohn's disease detections has been recorded since the middle of the 1980s. Morbidity in Great Britain and Sweden doubled reaching 3.1 for 100,000 infants, and in 1993 its spread made up 16.6 for 100,000.
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2002;
• Article: [Cases of stomach cancer in patients with common variable immunodeficiency].

  V A Osina, V G Rumiantsev
  Ėksperimental'nai͡a i klinicheskai͡a gastroėnterologii͡a = Experimental & clinical gastroenterology 02/2002;