V G Ionova

Publications (5)0.98 Total impact

• Article: [A state of hemorheological system in patients subjected to carotid endarterectomy with atherosclerotic lesion of the major cerebral arteries].

  A G Amintaeva, V G Ionova, D N Dzhibladze, O V Lagoda
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  ABSTRACT: To study the influence of changes in the blood rheological indices and blood coagulation on development, progression and clinical course of restenosis and thrombosis, 62 patients (mean age 63.4 +/- 6.0 years), were followed up for 2-15 years after carotid endarterectomy. Above 50% (maximum 70%) restenosis was observed in 7% cases. No critical postoperative restinosis was observed. In 12% patients, restenosis was accompanied with carotid artery occlusion and hematocrit, with fibrinogen (FG) being significantly increased in the absence of fibrinolytic activity (FL) elevation, indicating hemorheological disorders and homeostasis activation in such patients. Long-term follow-up showed that viscosity blood characteristics were elevated but functional activity of platelets and FA in patients did not differ from those in healthy subjects. At the same time, FG was high and fibrinolysis index was lower than mean statistical value that indicated predominance of blood procoagulation activity.
  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoi promyshlennosti Rossiiskoi Federatsii, Vserossiiskoe obshchestvo nevrologov [i] Vserossiiskoe obshchestvo psikhiatrov 02/2005; 105(3):23-6. · 0.12 Impact Factor
• Article: [Effects of helio-geomagnetic disturbances on the human hemorheological characteristics].

  V G Ionova, E A Sazanova, N P Sergeenko
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  ABSTRACT: Effects of geomagnetic disturbances on the rheological characteristics of blood and the homeostasis system were studies in 62 essentially healthy men. Rheological blood parameters, i.e. viscidity, hematocrit, fibrinogen, and erythrocyte and thrombocyte aggregation demonstrated statistically significant responses to alterations in the solar and geomagnetic activities. The authors raise a discussion about mechanisms of the physical processes in the near-Earth space on the blood rheological parameters.
  Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 02/2004; 38(2):33-7.
• Article: [The follow up of patients with extracranial pathology of the carotid arteries and ischemic disorders of cerebral circulation].

  D N Dzhibladze, A G Amintaeva, O V Lagoda, V G Ionova
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  ABSTRACT: According to the populational studies, about 50% of ischemic disorders of cerebral circulation, both persistent and transient, are induced by thrombotic or embolic complications of atherosclerotic plaques which produce an adverse effect on the large and small caliber arteries; about 20-25% is associated with lesion of the small diameter intracranial vessels, about 20% with embolism from the heart, and the remaining disorders fall within other rare causes. The prevalence of atherosclerotic lesions of the vessels feeding the brain, the severity of their clinical manifestations, insufficient efficacy of conservative therapy and the high risk of surgical treatment remain as before a matter of great medical and social concern. In connection with an appreciable progress of vascular surgery carotid endarterectoray (GEAE) as one of the radical approaches to correction of the pathology of the carotid artery segment is widespread at the large centers of vascular surgery of different countries. However, in spite of the fact that CEAE is an advanced and radical technique of preventive operation, it produces only a local effect on vascular diseases whereas the other, no less important pathogenetic mechanisms leading to disorders of cerebral circulation remain unchanged and demand drug correction to avoid repeated disorders of cerebral circulation. Analysis of the long-tern results evidences a stable and lasting effect of CEAE. The postoperative clinical manifestations can be used as the main criterion for the efficacy of CEAE, especially as compared to the purely conservative therepy. The results of the long-term follow up (over the period as long as 15 years) of a large group of operated patients demonstrate that the majority of them did not show the emergence of the new focal neurologic symptomatology in the ipsilateral hemisphere and only a small percentage of cases developed stroke. The major western statistics provide the analogous results.
  Angiologii͡a i sosudistai͡a khirurgii͡a = Angiology and vascular surgery 02/2003; 9(1):21-6.
• Article: [The wavelet analysis at heliobiological connections].

  Iu Ia Varakin, V G Ionova, E A Sazanova, N P Sergeenko
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  ABSTRACT: The Wavelet analysis of the time series of the number of insults per day and the variations of heliogeophysical indices was carried out. The patterns of Wavelet coefficients for both processes show a complex nonstationary behavior and the presence of periodic and acyclic constituents on different scales. During heliogeophysipal disturbances, the energy contribution to the processes increases more than threefold compared with the mean value on scales from three to five days.
  Biofizika 49(4):742-6. · 0.43 Impact Factor
• Article: [Response of the human body to heliogeophysical disturbanes].

  V G Ionova, E A Sazanova, N P Sergeenko, G V Gornostaeva, Kh D Kanonidi
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  ABSTRACT: A correlation between variations in the medical parameters and the heliogeophysical indices describing physical processes during solar storms was established. It was proposed that one of the reasons for the biotropic effects observed is rheological shifts of human blood during enhancement of solar activity. The influence of heliogeophysical disturbances on the rheological properties of blood was investigated.
  Biofizika 48(2):380-4. · 0.43 Impact Factor