T Laurell

Publications (2)7.09 Total impact

• Article: Emerging clinical applications of microchip-based acoustophoresis.

  A Lenshof, T Laurell
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  ABSTRACT: Acoustophoresis is currently in a state of transition from the academic laboratories, moving into the biomedical laboratories and industries. Clear areas of interest are seen in clinical diagnostics and therapeutics, where new approaches to cell handling and purification are emphasized as highly potent areas. This article outlines some of the basic unit operations of acoustophoresis, where applications as cell washing, binary separation, free-flow acoustophoresis, and affinity acoustophoresis are highlighted. The most recent steps to move acoustophoresis into clinical and preclinical applications are also presented.
  Journal of the Association for Laboratory Automation 12/2011; 16(6):443-9. · 1.42 Impact Factor
• Source

  Available from: Jörg P Kutter

  Article: Acoustic resonances in straight micro channels: beyond the 1D-approximation.

  S M Hagsäter, A Lenshof, P Skafte-Pedersen, J P Kutter, T Laurell, H Bruus
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  ABSTRACT: Acoustic actuation can be used to perform several tasks in microfluidic systems. In this paper, we investigate an acoustic separator through micro-PIV analysis in stop-flow mode and numerical simulations, and a good agreement between the two is found. Moreover, we demonstrate that it is not sufficient only to characterize devices in flow-through mode, since in these systems much different resonant patterns can result in similarly looking band formations. Furthermore, we conclude that extended 1D approximations of the acoustic radiation force are inadvisable, and instead, a 2D model is preferred. The results presented here provide valuable insight into the nature and functionality of acoustic microdevices, and should be useful in the interpretation and understanding of the same.
  Lab on a Chip 08/2008; 8(7):1178-84. · 5.67 Impact Factor