T Kobayashi

Chiba University, Tiba, Chiba, Japan

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Publications (1436)3114.96 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: Human herpesvirus-6 (HHV-6) is a common pathogen among children, classically presenting with fever and rash that resolves without specific therapy. HHV-6 can be reactivated in the immunosuppressed patient. After bone marrow and solid organ transplantation, HHV-6 has been linked to various clinical syndromes, including undifferentiated febrile illness, encephalitis, myelitis, hepatitis, pneumonitis, and bone marrow suppression. However, HHV-6 encephalitis after pancreatic transplant has rarely been reported. Early diagnosis and treatment of HHV-6 encephalitis may be important for affected patients. We report the case of a 53-year-old pancreas-after-kidney transplant recipient who initially presented with high fever and confusion 3 weeks after operation. We managed to save the patient's life and preserve the pancreas graft function. We also review previously reported cases of HHV-6B encephalitis in solid organ transplant recipients.
    Transplant Infectious Disease 07/2014; · 1.98 Impact Factor
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    ABSTRACT: We conducted an anatomical study to determine the best technique for transfer of the anterior interosseous nerve (AIN) for the treatment of proximal ulnar nerve injuries. The AIN, ulnar nerve, and associated branches were dissected in 24 cadaver arms. The number of branches of the AIN and length available for transfer were measured. The nerve was divided just proximal to its termination in pronator quadratus and transferred to the ulnar nerve through the shortest available route. Separation of the deep and superficial branches of the ulnar nerve by blunt dissection alone, was also assessed. The mean number of AIN branches was 4.8 (3 to 8) and the mean length of the nerve available for transfer was 72 mm (41 to 106). The transferred nerve reached the ulnar nerve most distally when placed dorsal to flexor digitorum profundus (FDP). We therefore conclude that the AIN should be passed dorsal to FDP, and that the deep and superficial branches of the ulnar nerve require approximately 30 mm of blunt dissection and 20 mm of sharp dissection from the point of bifurcation to the site of the anastomosis. The use of this technique for transfer of the AIN should improve the outcome for patients with proximal ulnar nerve injuries. Cite this article: Bone Joint J 2014;96-B:789-94.
    The bone & joint journal. 06/2014; 96-B(6):789-94.
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    ABSTRACT: Shock-induced devolatilization of volatile-bearing minerals has played an important role in the formation of the atmosphere and evolution of surface environments of terrestrial planets. The dependence of the degree of devolatilization on ambient pressure has not been investigated in detail before, even though ambient pressure dramatically affects the degree of devolatilization. In this study, we conducted shock recovery experiments on calcite (CaCO3) using newly designed sample containers for released gas analysis, and assessed the dependence of the degree of devolatilization on the partial pressure of CO2. Our results clearly show that the degree of devolatilization increases as the sample container volume increases and the initial mass of calcite decreases.
    Journal of Physics Conference Series 05/2014; 500(6):062001.
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    ABSTRACT: Maintaining hepatic inflow and appropriate venous drainage is important for maximizing the capacity of the retrieved graft in liver transplantation. Here, we report a successful case of multiple hepatic vein (HV) reconstruction using an all-in-one sleeve patch graft of the autologous great saphenous vein to ensure adequate blood flow through the HV. A patient with hepatocellular carcinoma caused by hepatitis C virus-induced cirrhosis underwent living donor liver transplantation using a right lobe graft. A preoperative dynamic computed tomography scan and intraoperative findings revealed that the graft had three middle HV tributaries, a superficial vein, segment VIII HV (V8), and segment V HV (V5). The openings of the superficial vein and V8 were located very close to that of the right hepatic vein (RHV) in the cutting surface. Each HV had significant diameter and drainage territory requiring reconstruction. An autologous great saphenous vein was used to create a sleeve patch to incorporate the close-packed HV openings. The autologous sleeve patch graft was sutured to the openings of the RHV and the superficial vein and the hole created on the sleeve patch graft was anastomosed to the openings of V8 directly on the back table to create an all-in-one sleeve patch. For the V5 reconstruction, the recipient's intrahepatic portal vein graft was used to create an interpositional conduit from the recipient's V5 to the inferior vena cava. The postoperative course was uneventful and postoperative studies revealed good graft function with excellent blood flow in the HV.
    Transplantation Proceedings 04/2014; 46(3):982-5. · 0.95 Impact Factor
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    ABSTRACT: The purposes of this study were to study and compare clinical and functional outcomes after simultaneous deceased donor pancreas and kidney transplantation (SPK DD), simultaneous deceased donor pancreas and living donor kidney transplantation (SPK DL), and simultaneous living donor pancreas and kidney transplantation (SPK LL). From January 1, 1996 to September 1, 2005, 8918 primary, simultaneous pancreas and kidney transplantation (SPK) procedures were reported to the International Pancreas Transplant Registry. Of these, 8764 (98.3%) were SPK DD, 115 (1.3%) were SPK DL, and 39 (0.4%) were SPK LL. We compared these 3 groups with regard to several endpoints including patient and pancreas and kidney graft survival rates. The 1-year and 3-year patient survival rates for SPK DD were 95% and 90%, 97% and 95% for SPK DL, and 100% and 100% for SPK LL recipients, respectively (P ≥ .07). The 1-year and 3-year pancreas graft survival rates for SPK DD were 84% and 77%, 83% and 71% for SPK DL, and 90% and 84% for SPK LL recipients, respectively (P ≥ .16). The 1-year and 3-year kidney graft survival rates for SPK DD were 92% and 84%, 94% and 86% for SPK DL, and 100% and 89% for SPK LL recipients, respectively (P ≥ .37). Patient survival rates and graft survival rates for pancreas and kidney were similar among the 3 groups evaluated in this study.
    Transplantation Proceedings 04/2014; 46(3):948-53. · 0.95 Impact Factor
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    ABSTRACT: This is the first successful report of a laparoscope-assisted Hassab's operation for esophagogastric varices after living donor liver transplantation (LDLT). A 35-year-old man underwent LDLT using a right lobe graft as an aid for primary sclerosing cholangitis (PSC) in 2005. Follow-up endoscopic and computed tomography (CT) examinations showed esophagogastric varices with splenomegaly in 2009 that increased (esophageal varices [EV]: locus superior [Ls], moderator enlarged, beady varices [F2], medium in number and intermediate between localized and circumferential red color signs [RC2]; gastric varices [GV]: extension from the cardiac orifice to the fornix [Lg-cf], moderator enlarged, beady varices [F2], absent red color signs [RC0]). A portal venous flow to the esophagogastric varices through a large left gastric vein was also confirmed. Preoperative Child-Pugh was grade B and score was 9. Because these esophagogastric varices had a high risk of variceal bleeding, we proceeded with a laparoscope-assisted Hassab's operation. Operative time was 464 minutes. Blood loss was 1660 mL. A graft liver biopsy was also performed and recurrence of PSC was confirmed histologically. It was suggested that portal hypertension and esophagogastric varices were caused by recurrence of PSC. Postoperative complications were massive ascites and enteritis. Both of them were treated successfully. This patient was discharged on postoperative day 43. Follow-up endoscopic study showed improvement in the esophagogastric varices (esophageal varices [EV]: locus superior [Ls], no varicose appearance [F0], absent red color signs [RC0], gastric varices [GV]: adjacent to the cardiac orifice [Lg-c], no varicose appearance [F0], absent red color signs [RC0]) at 6 months after the operation. We also confirmed the improvement of esophagogastric varices by serial examinations of CT.
    Transplantation Proceedings 04/2014; 46(3):986-8. · 0.95 Impact Factor
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    ABSTRACT: A 61-year-old Japanese woman, who had undergone hemodialysis because of chronic glomerulonephritis, received a living renal transplant from her ABO blood type-compatible spouse. HLA typing of A, B and DRB showed 3/6 mismatches. Complement-dependent cytotoxicity crossmatches, HLA antibody screening with the use of flow panel reactive antibody (PRA), and flow cytometry crossmatches (FCXM) were all negative. Tacrolimus, mycophenolate mofetil, methylprednisolone (MP), and basiliximab induction were used as the standard immunosuppressive therapy. After renal transplantation, her serum creatinine level favorably decreased, but urine output was not sufficiently obtained, contrary to our expectations. Doppler sonography revealed disappearance of diastolic arterial flow on postoperative day 2. The episode biopsy showed acute antibody-mediated rejection (AMR) based on the current Banff classification, although FCXM and flow PRA were still negative. To determine the cause of acute AMR, we expanded the HLA typing at high resolution levels to Cw, DQB1, and DPB1. Retrospective analysis of perioperative sera demonstrated the presence of low levels of donor-specific HLA IgG and moderate levels of IgM antibody against DQB1 before transplantation. There was an elevation of IgM antibody at the time of rejection, whereas IgG antibody showed no remarkable change. AMR was successfully treated with plasma exchange, low-dose intravenous immunoglobulin, high-dose intravenous MP pulse, and rituximab.
    Transplantation Proceedings 03/2014; 46(2):640-3. · 0.95 Impact Factor
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    ABSTRACT: We conducted shock-induced gas recovery experiments of calcite. Our results show that the degree of devolatilization strongly depends on the container volume.
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    ABSTRACT: For estimation of the bulk density of the lunar uppermost layers, the effective dielectric constant has been determined by using the Kaguya radar sounder data.
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    ABSTRACT: We demonstrate a drastic improvement in the efficiency of rare-element-free graphene nanomesh (GNM) magnets with saturation magnetization values as large as ∼10−4 emu/mm2, which are 10–100 times greater than those in previous GNM magnets hydrogenated by only annealing under a hydrogen molecule (H2) atmosphere, even at room temperature. This improvement is realized by a significant increase in the area of the mono-H-terminated pore edges by using hydrogen silsesquioxane resist treatment with electron beam irradiation, which can produce mono-H by detaching H-silicon (Si) bonds. This result must open the door for industrial applications of graphene magnets to rare-element-free magnetic and spintronic systems.
    Applied Physics Letters 01/2014; 104(25):252410-252410-4. · 3.79 Impact Factor
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    ABSTRACT: Background Recipients with autoimmune hepatitis (AIH) have a higher incidence of both rejection and recurrence after liver transplantation (LT) when compared with cholestatic liver diseases such as primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). This is due to the lack of an immune monitoring system, making it difficult to control immunosuppressant agents. In this study, we examine the benefit of the carboxyfluorescein diacetate succinimidyl ester–mixed lymphocyte reaction (CFSE-MLR) monitoring system for evaluating the immune status in recipients with AIH and PBC/PCS after LT. Method Recipients who underwent LT (9 AIH and 11 PBC/PSC) from 2002 to 2013 at Hiroshima University were enrolled in this study. The correlation between the result of CFSE-MLR and the outcome, bacteremia, rejection, and/or recurrence was examined. Result The cumulative survival rates for 5 years after LT revealed preferable outcomes for both groups (AIH 85.7%, PBC/PCS 80%). None of the recipients in the AIH group developed bacteremia during 90 days after LT, whereas three recipients from the PBC/PCS group (27%) developed bacteremia. The recurrence rate (AIH 33%, PBC/PSC 27%) was the same as the reported data; however, there was a lower incidence of acute rejection rate in our institution (AIH 11%, PBC/PSC 27%). In the CFSE-MLR assay, the stimulation index of CD4+ T cells in the anti-self reaction was increased in recurrent cases, whereas no elevation of anti-donor reaction was observed in either CD4+ or CD8+ T cells. Conclusion Optimization of the immunosuppressant agents based on the CSFE-MLR assay after LT achieved a preferable outcome in recipients with both AIH and PBC/PCS. Therefore, CFSE-MLR assay might be a useful tool for predicting the recurrence of autoimmune liver diseases by monitoring anti-self reactivity of CD4+ T cells.
    Transplantation Proceedings 01/2014; 46(3):785–789. · 0.95 Impact Factor
  • D.F. Wang, Y. Suzuki, T. Kobayashi, T. Itoh, R. Maeda
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    ABSTRACT: A cantilever-based, oscillating type MEMS direct current sensor (abbreviated as DC sensor), integrated with both actuating and sensing piezoelectric plates, as well as a micromagnet is proposed to satisfy the increasing needs of DC power supply for monitoring electrical consumption by either a single-wire or two-wire appliance cord. A prototype MEMS DC sensor, with a measured resonant frequency of 23 Hz, was microfabricated and characterised. In the case of a two-wire electrical appliance cord, it was found that the change in the peak-to-valley value (abbreviated as P-V value) of the output voltage was approximately proportional to the applied DC, and increased from 10.4 to 43.2 mV when the DC increased from 0 to 2 A under an excitation voltage of 5 Vpp. The shift of the resonant frequency because of the applied DC is believed to account for the change in the P-V value (or the maximum value) of the output voltage. In summary, the proposed MEMS DC sensor integrated with both actuating and sensing piezoelectric plates was observed to measure the output voltage constantly and linearly over the applied DC directly in a two-wire appliance without using a cord separator.
    Micro & Nano Letters 12/2013; 8(12):858-860. · 0.85 Impact Factor
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    ABSTRACT: This research reports an AlN cantilever with an air chamber for a wake-up switch triggered by air pressure change. The proposed sensor is designed to fulfil both high sensitivity and low power consumption. By combining an air chamber to the one side of the AlN cantilever surface, the barometric pressure change generates a piezoelectric voltage. Thus, a wake-up switch triggered by air pressure change can be achieved using an AlN cantilever. The size of the fabricated AlN cantilever was 2000 μm × 1000 μm × 2 μm. The sensitivity to static differential pressure was 11.5 mV/Pa at the range of -20 Pa to 20 Pa. We evaluated the response of the sensor, which was composed of the AlN cantilever and the chamber of 60 ml in volume, when air pressure change was applied. The output voltage increased with increasing the applied air pressure change. It was observed that the maximum output voltage of 50 mV was generated when the air pressure change was 13 Pa.
    Journal of Physics Conference Series 12/2013; 476(1):2122-.
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    ABSTRACT: Piezoelectric vibration energy harvester arrays using Pb(Zr,Ti)O3 thin films on 200 mm SOI wafers were fabricated. In-plane distribution of influence of bipolar pulse poling technique on direct current (DC) power output from the harvesters was investigated. The results indicate that combination poling treatment of DC and bipolar pulse poling increases a piezoelectric property and reduces a dielectric constant. It means that this poling technique improves the figure of merit of sensors and harvesters. Maximum DC power from a harvester treated by DC poling after bipolar pulse poling is about five times larger than a one treated by DC poling only.
    Journal of Physics Conference Series 12/2013; 476(1):2132-.
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    ABSTRACT: We proposed one novel MEMS-based thermometer with low power-consumption for animal/human health-monitoring network application. The novel MEMS-based thermometer was consisted of triple-beam bimorph arrays so that it could work in a continuous temperature range. Neither continuous electric supply nor A/D converter interface is required by the novel thermometer owing to the well-known deflection of bimaterials cantilever upon temperature changes. The triple-beam structure also facilitated the novel thermometer with excellent fabrication feasibility by conventional microfabrication technology. The parameters of the triple-beam bimorph arrays were determined by finite element analysis with ANSYS program. Low stress Au and Mo metal films were used as top and bottom layer, respectively. The deflection of the triple-beam bimorphs were measured on a home-made heating stage by a confocal scanning laser microscopy. The novel bimorphs had temperature responses similar to traditional single-beam bimorphs. Initial bend of the prepared triple-beam bimorphs were dominantly determined by their side beams. The sensitivity of the novel thermometer was as high as 0.1°C. Experimental results showed that the novel thermometer is attractive for network sensing applications where the power capacity is limited.
    Proc SPIE 07/2013;
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    ABSTRACT: We have developed piezoelectric microelectromechanical systems (MEMS) switches and applied them to ultra-low power wireless sensor nodes, to monitor the health condition of chickens. The piezoelectric switches have 'S'-shaped piezoelectric cantilevers with a proof mass. Since the resonant frequency of the piezoelectric switches is around 24 Hz, we have utilized their superharmonic resonance to detect chicken movements as low as 5–15 Hz. When the vibration frequency is 4, 6 and 12 Hz, the piezoelectric switches vibrate at 0.5 m s−2 and generate 3–5 mV output voltages with superharmonic resonance. In order to detect such small piezoelectric output voltages, we employ comparator circuits that can be driven at low voltages, which can set the threshold voltage (Vth) from 1 to 31 mV with a 1 mV increment. When we set Vth at 4 mV, the output voltages of the piezoelectric MEMS switches vibrate below 15 Hz with amplitudes above 0.3 m s−2 and turn on the comparator circuits. Similarly, by setting Vth at 5 mV, the output voltages turn on the comparator circuits with vibrations above 0.4 m s−2. Furthermore, setting Vth at 10 mV causes vibrations above 0.5 m s−2 that turn on the comparator circuits. These results suggest that we can select small or fast chicken movements to utilize piezoelectric MEMS switches with comparator circuits.
    Smart Materials and Structures 07/2013; 22(9):095001. · 2.02 Impact Factor
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    ABSTRACT: The temporal and spatial responses of electron channels (the electron density, ne, and the electron temperature, Te) and ion channels (the ion temperature, Ti, and the toroidal rotation velocity, V) to central electron cyclotron heating (ECH) have been investigated in positive shear H-mode plasmas with a relatively peaked Ti profile and internal transport barrier (ITB) plasmas on JT-60U. Ion temperature decreases with ECH after the increase in the electron temperature in the core region. The time scale of the change in Ti is ≈30–60 ms in H-mode plasmas and almost constant in radius. In ITB plasmas, the time scale is shorter around the ITB foot and becomes longer inside the ITB foot. The experimentally measured causality indicates that the decrease in Ti is consistent with the ion temperature gradient critical gradient reduction. This is also verified through a comparison with linear gyrokinetic stability analyses. The electron heat diffusivity increases with ECH in both H-mode and ITB plasmas, correlating to the increase in the ion heat diffusivity. Electron density with a relatively flat ne profile does not decrease with ECH. On the other hand, the electron density with a peaked ne profile decreases with ECH. The flattening of the ne profile is observed after the increase in the electron temperature in the core region. The time scale of the change in ne is about 200–350 ms. Linear gyrokinetic stability analyses imply that the growth rate of the trapped electron modes, which increase outward particle flux, becomes more pronounced during ECH. The counter intrinsic rotation with ECH is identified on H-mode plasmas with a small torque input (BAL-NBI). The counter intrinsic rotation is generated after the increase in the electron temperature and correlates to the change in the electron temperature with ECH around the EC deposition. The radial region where the counter intrinsic rotation is observed is wider than the radial region where the electron temperature varies with ECH. The time scale of the change in the toroidal rotation velocity is about 90–200 ms around the ECH deposition and longer than the time scale of the change in Te and Ti.
    Nuclear Fusion 07/2013; 53(8):083022. · 2.73 Impact Factor
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    ABSTRACT: We proposed a thin piezoelectric cantilever to measure an airflow velocity change. An airflow sensor using a PZT cantilever and a flow channel was fabricated. We measured the relationship between the airflow velocity change and the piezoelectric voltage of the cantilever. The dimensions of the sensor and the cantilever are 25 mm × 20 mm × 20 mm and 1500 μm × 1000 μm × 2 μm, respectively. We evaluated the effect of the diameter of the flow channel on the sensor response. It was demonstrated that the fabricated sensor generated an output voltage of several millivolts when the airflow velocity changed at a rate of approximately 1 m/s. It was observed that the output voltage increased as the diameter of the flow channel became small.
    Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), 2013 Symposium on; 04/2013
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    ABSTRACT: This paper reports a wake-up switch using a piezoelectric differential pressure sensor in order to reduce the power consumption of a wireless sensor node. Air pressure change surrounding the sensor is detected by using a Pb(Zr, Ti)O3(PZT) thin film cantilever with the dimension of 1500 μm × 1000 μm × 2 μm. The sensor has high sensitivity with low power consumption due to its thin cantilever and low capacitance. The sensitivity was 2.4 mV/Pa from -30 Pa to 30 Pa. It was demonstrated that the fabricated sensor performed as a wake-up switch when pressure varies in 10 Pa with low power consumption.
    Intelligent Sensors, Sensor Networks and Information Processing, 2013 IEEE Eighth International Conference on; 04/2013
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    ABSTRACT: The angular distribution of proton-9C elastic scattering at 277–300 MeV/nucleon was measured with a newly designed recoil proton spectrometer. The angular distribution was analyzed using the relativistic impulse approximation. The root-mean-square matter radius of 9C was deduced to be 2.43−0.28+0.55 fm with different two-parameter Fermi density distributions for protons and neutrons.
    Physical Review C 03/2013; 87(3). · 3.72 Impact Factor

Publication Stats

15k Citations
3,114.96 Total Impact Points


  • 2014
    • Chiba University
      • Department of Orthopedic Surgery
      Tiba, Chiba, Japan
  • 2003–2014
    • Hiroshima University
      • • Department of Gastroenterological and Transplant Surgery
      • • Department of Surgery
      • • Faculty of Medicine
      • • Research Institute for Radiation Biology and Medicine (RIRBM)
      • • Department of Surgery II
      Hirosima, Hiroshima, Japan
    • University of Pécs
      • Institute of Physics
      Pécs, Baranya megye, Hungary
    • The Graduate University for Advanced Studies
      Миура, Kanagawa, Japan
  • 2001–2014
    • National Institute for Materials Science
      • Advanced Materials Laboratory
      Tsukuba, Ibaraki, Japan
  • 1987–2014
    • Nagoya University
      • • Division of Surgery
      • • Division of Cell Science
      • • Department of Chemical Engineering
      Nagoya, Aichi, Japan
    • University of California, Los Angeles
      Los Angeles, California, United States
  • 2008–2013
    • Japan Atomic Energy Agency
      • Nuclear Science and Engineering Directorate
      Muramatsu, Niigata, Japan
  • 1996–2013
    • National Institute for Basic Biology
      Okazaki, Aichi, Japan
  • 1994–2013
    • Tohoku University
      • • Department of Physics
      • • Institute of Development, Aging and Cancer
      • • Graduate School of Pharmaceutical Sciences
      Sendai, Kagoshima, Japan
    • University of Oxford
      • Sir William Dunn School of Pathology
      Oxford, ENG, United Kingdom
    • Hokkaido University
      • Laboratory of Biochemistry (School of Veterinary Medicine)
      Sapporo-shi, Hokkaido, Japan
    • Rikkyo University
      • Department of Physics
      Tokyo, Tokyo-to, Japan
  • 2012
    • Tachikawa Hospital
      Edo, Tōkyō, Japan
  • 2000–2012
    • Niigata University
      • • Division of Digestive and General Surgery
      • • Division of Periodontology
      Niahi-niigata, Niigata, Japan
    • Santen Pharmaceutical Co., Ltd.
      Ōsaka, Ōsaka, Japan
    • Karolinska University Hospital
      • Department of Clinical Chemistry
      Stockholm, Stockholm, Sweden
  • 1996–2012
    • Hoshi University
      • Department of Physiology and Morphology
      Shinagawa, Tōkyō, Japan
  • 2008–2011
    • Nippon Telegraph and Telephone
      Edo, Tōkyō, Japan
  • 2005–2011
    • National Institute of Advanced Industrial Science and Technology
      • Advanced Manufacturing Research Institute
      Tsukuba, Ibaraki, Japan
    • Shimane University
      • Interdisciplinary Faculty of Sciences and Engineering
      Matsu, Shimane Prefecture, Japan
    • Fisheries Research Agency
      Yokohama, Kanagawa, Japan
  • 2010
    • Korean Institute of Geoscience and Mineral Resources
      Sŏul, Seoul, South Korea
    • Southwest University in Chongqing
      Pehpei, Chongqing Shi, China
    • Johns Hopkins University
      • Department of Chemistry
      Baltimore, Maryland, United States
  • 2009
    • Ehime University
      Matuyama, Ehime, Japan
  • 2005–2009
    • University of Hyderabad
      • Department of Animal Sciences
      Hyderābād, State of Andhra Pradesh, India
  • 1991–2009
    • Ishikawa Prefectural Central Hospital
      Ishiza, Okinawa, Japan
  • 1992–2008
    • RIKEN
      • Nishina Center for Accelerator-Based Science (RNC)
      Вако, Saitama, Japan
  • 2006
    • Nakano Children's Hospital
      Ōsaka, Ōsaka, Japan
    • Robert Wood Johnson University Hospital
      New Brunswick, New Jersey, United States
    • Hungarian Academy of Sciences
      • Institute for Solid State Physics and Optics
      Budapeŝto, Budapest, Hungary
  • 2004–2006
    • Japan Synchrotron Radiation Research Institute (JASRI)
      Tatsuno, Hyōgo, Japan
    • Hokuriku Central Hospital
      Nanto-shi, Toyama, Japan
  • 1990–2006
    • University of Tsukuba
      • • Applied Physics
      • • Institute of Clinical Medicine
      • • Department of Immunology and Medical Genetics
      Tsukuba, Ibaraki, Japan
  • 1997–2005
    • Kagawa University
      • Department of Radiology
    • Oita University
      • Research Laboratory Center
      Ōita, Ōita, Japan
  • 1989–2005
    • Kyoto University
      • • Research Reactor Institute
      • • Graduate School of Medicine / Faculty of Medicine
      • • Department of Orthopaedic Surgery
      Kyoto, Kyoto-fu, Japan
    • NTT DATA Corporation
      Edo, Tōkyō, Japan
    • The University of Tokushima
      • School of Medicine
      Tokusima, Tokushima, Japan
    • National Institute of Radiological Sciences
      Tiba, Chiba, Japan
    • Keio University
      • Department of Internal Medicine
      Edo, Tōkyō, Japan
    • Chiba Institute of Science
      Tiba, Chiba, Japan
  • 1988–2005
    • The University of Tokyo
      • • Department of Physics
      • • Faculty & Graduate School of Medicine
      • • Division of Surgery
      • • Institute of Medical Science
      • • Division of Internal Medicine
      Tokyo, Tokyo-to, Japan
  • 1982–2005
    • Shinshu University
      • • Department of Radiology
      • • Department of Internal Medicine I
      • • Department of Chemistry
      • • Department of Medicine
      Shonai, Nagano, Japan
  • 1999–2004
    • Mitsubishi Corp.
      Kamakura, Kanagawa, Japan
    • Karolinska Institutet
      Solna, Stockholm, Sweden
    • Ochanomizu University
      • Department of Biology
      Edo, Tōkyō, Japan
  • 1992–2004
    • Osaka Medical Center for Cancer and Cardiovascular Diseases
      Ōsaka, Ōsaka, Japan
  • 1988–2004
    • Kanazawa University
      • • Graduate School of Medical Sciences
      • • School of Medicine
      Kanazawa, Ishikawa, Japan
  • 2001–2002
    • Tokyo Women's Medical University
      • Department of Dermatology
      Edo, Tōkyō, Japan
  • 1998–2001
    • St. Marianna University School of Medicine
      • • Department of Otolaryngology
      • • Institute of Medical Science
      Kawasaki, Kanagawa-ken, Japan
    • University of Hawaiʻi at Mānoa
      • Department of Zoology
      Honolulu, HI, United States
  • 1997–2001
    • Tsukuba Research Institute
      Edo, Tōkyō, Japan
  • 1997–2000
    • Juntendo University
      • Department of Neurology
      Tokyo, Tokyo-to, Japan
  • 1994–2000
    • National Institutes of Health
      • Laboratory of Cell Biology
      Bethesda, MD, United States
  • 1992–2000
    • Nagoya City University
      • • Department of Internal Medicine
      • • Faculty of Pharmaceutical Sciences
      Nagoya, Aichi, Japan
    • Kanazawa Medical University
      • • Department of Urology
      • • Department of Radiology
      Kanazawa, Ishikawa, Japan
  • 1988–2000
    • Toranomon Hospital
      Edo, Tōkyō, Japan
  • 1984–2000
    • Tokyo Medical and Dental University
      • • Department of Neuropathology
      • • Department of Medicine
      • • Faculty of Medicine
      Edo, Tōkyō, Japan
  • 1978–2000
    • Kyushu University
      • • Department of Neurology
      • • Faculty of Medical Sciences
      • • Department of Neuropathology
      Fukuoka-shi, Fukuoka-ken, Japan
  • 1992–1999
    • Aichi Medical University
      • Division of Internal Medicine
      Okazaki, Aichi, Japan
  • 1991–1999
    • Toshiba Corporation
      Edo, Tōkyō, Japan
  • 1989–1999
    • Hokkaido University Hospital
      • • Division of Internal Medicine II
      • • Division of Cardiovascular Medicine
      Sapporo-shi, Hokkaido, Japan
  • 1987–1999
    • Hitachi, Ltd.
      Edo, Tōkyō, Japan
  • 1996–1998
    • Health Sciences University of Hokkaido
      • Department of Pharmacology
      Tōbetsu, Hokkaido, Japan
  • 1994–1998
    • Kobe Pharmaceutical University
      Kōbe, Hyōgo, Japan
  • 1971–1998
    • Tokyo Metropolitan University
      • • Department of Chemistry
      • • Department of Physics
      Tokyo, Tokyo-to, Japan
  • 1994–1997
    • Kitasato University
      • • School of Science
      • • Department of Pharmaceutical Sciences
      Edo, Tōkyō, Japan
  • 1993–1997
    • Meijo University
      • Department of Pharmacology
      Nagoya-shi, Aichi-ken, Japan
    • Tokyo Saiseikai Central Hospital
      Edo, Tōkyō, Japan
    • Università degli Studi di Torino
      Torino, Piedmont, Italy
    • National Hospital Organization Kyushu Cancer Center
      Hukuoka, Fukuoka, Japan
    • Kushiro City General Hospital
      Kusiro, Hokkaidō, Japan
    • Dokkyo Medical University
      • Division of Clinical and Molecular Pathology
      Tochigi, Tochigi-ken, Japan
  • 1978–1996
    • Osaka University
      • Department of Electrical and Electronics Engineering
      Suika, Ōsaka, Japan
  • 1995
    • Kagoshima University
      Kagosima, Kagoshima, Japan
    • Kazusa DNA Research Institute
      Kizarazu, Chiba, Japan
    • Nara Institute of Science and Technology
      • Graduate School of Biological Sciences
      Ikuma, Nara, Japan
  • 1993–1995
    • The Jikei University School of Medicine
      • • Department of Biochemistry
      • • Department of Internal Medicine
      Edo, Tōkyō, Japan
  • 1992–1993
    • National Cancer Center, Japan
      • Center for Cancer Control and Information Services
      Edo, Tōkyō, Japan
  • 1990–1992
    • Fukuoka Institute of Technology
      Hukuoka, Fukuoka, Japan
  • 1986–1991
    • Waseda University
      • School of Education
      Tokyo, Tokyo-to, Japan
  • 1986–1989
    • University of Occupational and Environmental Health
      • School of Medicine
      Kitakyūshū, Fukuoka-ken, Japan
  • 1978–1983
    • Kobe University
      • • Department of Electrical and Electronic Engineering
      • • Division of Marine Engineering
      Kōbe-shi, Hyogo-ken, Japan
  • 1979
    • Kurume University
      • Department of Chemistry
      Куруме, Fukuoka, Japan
    • Kyushu Institute of Technology
      Hukuoka, Fukuoka, Japan