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Publications (3)0 Total impact

  • Sharat Kumar, Suttur S Malini
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    ABSTRACT: The main objective of the present work was to study extent and magnitude of the relationship between age and semen volume, sperm count and sperm motility, in control and infertile group and to elucidate the prevalence of different infertile condition in men. The study was carried out on 447 couples who visited the infertility clinics of Mysore in the year 2008-2009 for not having children even after one year of marriage with unprotected sex. Cases were evaluated manually according to World Health Organization (WHO) standards and analyzed statistically with the help of paired t-test, using SPSS version 10 Software. The P<0.05 values were considered statistically significant. The results obtained showed the gradual decrease in the semen parameters as age progresses in control males (p<0.05) and higher prevalence of asthenospermia in infertile group without significance with age factor. The data clearly illustrate an aging effect on semen characteristics, where the semen volume, sperm count and sperm motility decreased as age of subjects progressed. INTRODUCTION spermatozoa display marked heterogeneity, and therefore a variety of sperm abnormalities may be found Male infertility is a multifactorial condition in the semen samples even those from fertile men (Chia encompassing a wide variety of disorders. et al., 1998). But no such studies are done in Karnataka Approximately 15% of couples within reproductive age with large sample size. In this view the present study experience infertility, and more than a quarter of was carried out to examine the extent and magnitude of infertility cases may be attributed to male factors alone the relationships between age and semen volume, (Templeton, 1995; Kuhnert and Nieschlag, 2004). The sperm count and sperm motility in normal and infertile condition could also be congenital or acquired whereas males during the year 2008 to 2009, in Mysore up to 10% of infertility cannot be explained medically Karnataka. and affects males with their partners resulting in emotional and psychological trauma (Poongothai et al., Materials and Methods 2009). Semen quality is generally considered to be a The study was carried out on 447 couples who have proxy measure of male fertility. There are also a growing visited the infertility clinics of Mysore in the year 2008-number of reports about regional and temporal 2009. Only the male partners were included in this differences in semen quality from centers around the study. 100 men with normal semen parameters were world (Fisch et al., 1996; Berling et al., 1997; Andolz et also included in the present study as a control group. al., 1999; Itoh et al., 2001; Jorgensen et al., 2001). The Cases were assessed for three parameters namely decrease in fertility rates comes with aging is often much semen volume, sperm count, sperm motility and it is more apparent in women than in men. It is well-known strictly assessed manually according to World Health that aging in females is a significant contributor to Organization (WHO) standards. Ejaculates were human infertility, primarily due to the precipitous loss of obtained by masturbation after 3–5 days of abstinence functional oocytes in women by their late thirties (Tietze, and were allowed to liquefy at room temperature and the 1957; Joffe and Li 1994; Ventura et al., 1995). analysis was carried out. Men were divided into four In males, fertility does decrease in old age as well, groups based on their age as group I (20-29yrs), group II although it isn't necessarily permanent and it is almost (30-39yrs) group III (40-49yrs) and group IV (50-59yrs) never obvious without lab tests. Several studies have in both controls and infertile males. The seminal reported strong association of increase age in men with characteristics were compared for both the control and a decline in semen parameters (Haidl et al., 1996; infertile groups and the results obtained were analyzed Centola and Eberly, 1999; Kidd et al., 2001). Human statistically with the help of paired t-test, using SPSS
  • Sharat Kumar, Suttur S Malini
    [Show abstract] [Hide abstract]
    ABSTRACT: The main objective of the present work was to study extent and magnitude of the relationship between age and semen volume, sperm count and sperm motility, in control and infertile group and to elucidate the prevalence of different infertile condition in men. The study was carried out on 447 couples who visited the infertility clinics of Mysore in the year 2008-2009 for not having children even after one year of marriage with unprotected sex. Cases were evaluated manually according to World Health Organization (WHO) standards and analyzed statistically with the help of paired t-test, using SPSS version 10 Software. The P<0.05 values were considered statistically significant. The results obtained showed the gradual decrease in the semen parameters as age progresses in control males (p<0.05) and higher prevalence of asthenospermia in infertile group without significance with age factor. The data clearly illustrate an aging effect on semen characteristics, where the semen volume, sperm count and sperm motility decreased as age of subjects progressed. INTRODUCTION spermatozoa display marked heterogeneity, and therefore a variety of sperm abnormalities may be found Male infertility is a multifactorial condition in the semen samples even those from fertile men (Chia encompassing a wide variety of disorders. et al., 1998). But no such studies are done in Karnataka Approximately 15% of couples within reproductive age with large sample size. In this view the present study experience infertility, and more than a quarter of was carried out to examine the extent and magnitude of infertility cases may be attributed to male factors alone the relationships between age and semen volume, (Templeton, 1995; Kuhnert and Nieschlag, 2004). The sperm count and sperm motility in normal and infertile condition could also be congenital or acquired whereas males during the year 2008 to 2009, in Mysore up to 10% of infertility cannot be explained medically Karnataka. and affects males with their partners resulting in emotional and psychological trauma (Poongothai et al., Materials and Methods 2009). Semen quality is generally considered to be a The study was carried out on 447 couples who have proxy measure of male fertility. There are also a growing visited the infertility clinics of Mysore in the year 2008-number of reports about regional and temporal 2009. Only the male partners were included in this differences in semen quality from centers around the study. 100 men with normal semen parameters were world (Fisch et al., 1996; Berling et al., 1997; Andolz et also included in the present study as a control group. al., 1999; Itoh et al., 2001; Jorgensen et al., 2001). The Cases were assessed for three parameters namely decrease in fertility rates comes with aging is often much semen volume, sperm count, sperm motility and it is more apparent in women than in men. It is well-known strictly assessed manually according to World Health that aging in females is a significant contributor to Organization (WHO) standards. Ejaculates were human infertility, primarily due to the precipitous loss of obtained by masturbation after 3–5 days of abstinence functional oocytes in women by their late thirties (Tietze, and were allowed to liquefy at room temperature and the 1957; Joffe and Li 1994; Ventura et al., 1995). analysis was carried out. Men were divided into four In males, fertility does decrease in old age as well, groups based on their age as group I (20-29yrs), group II although it isn't necessarily permanent and it is almost (30-39yrs) group III (40-49yrs) and group IV (50-59yrs) never obvious without lab tests. Several studies have in both controls and infertile males. The seminal reported strong association of increase age in men with characteristics were compared for both the control and a decline in semen parameters (Haidl et al., 1996; infertile groups and the results obtained were analyzed Centola and Eberly, 1999; Kidd et al., 2001). Human statistically with the help of paired t-test, using SPSS