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ABSTRACT: Obesity is highly prevalent and has several adverse effects on health. Its treatment is thus warranted and must aim to modify dietary and physical activity habits. The opinion of this association is that anorexigenic drugs with cathecolaminergic action (diethylpropion, phentermine, mazindol and phenylpropanolamine) or serotoninergic action (fenfluoramine and fluoxetine) may be used in moderate or severe obesity (BMI > 30 kg/m2) after a complete clinical assessment and in the context of an integral medical treatment. This association recommends a close surveillance of the use of these drugs, specially when formulated as non-proprietary prescriptions.
Revista medica de Chile 06/1995; 123(5):637-40. · 0.33 Impact Factor
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ABSTRACT: Eight patients with severe HG, were treated through parenteral nutrition. This treatment was formulated as aminoacid, sucrose solution and fat solution (3 of 8 cases), blended with vitamins electrolites and oligoelements. The procedure lasted 5 at 16 days conforming a total of 77 days. Seven newborns were term delivery, and one case was missed abortion. Like this, there were no complications detected and clinical wellbeing was reached, successfully.
Revista chilena de obstetricia y ginecología 02/1994; 59(5):378-82.
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ABSTRACT: The aim of the present study was to assess the effect of severe head injury over resting energy expenditure and nitrogen losses. Eight patients with severe head trauma (mean Glasgow scale of 4.9 +/- 1.6), subjected to emergency craniotomy were studied; four patients had septic complications and none received steroids. Energy expenditure was measured using indirect calorimetry and nitrogen losses were assessed measuring 24 h urea nitrogen excretion on days 1, 4, 7 and 10 of the postoperative period. Twelve healthy males composed the control group. Measured energy expenditure in patients, evaluated in 22 occasions, was 35 +/- 9.8 Kcal/kg/day or 145 +/- 41% of the estimation according to Harris-Benedict equations, compared to 22.0 +/- 4.6 Kcal/kg/day or 89.9 +/- 17.5% in the control group (p < 0.001). 24 h urinary urea nitrogen excretion in patients was 18 +/- 12 g/day (range 5.2-46.9) and the catabolic index was 7.4 +/- 13.5. It is concluded that, due to the great individual variability in measured energy expenditure in these patients and their hypercatabolism, indirect calorimetry and nitrogen balance studies become useful tools to perform an adequate nutritional support.
Revista medica de Chile 06/1993; 121(6):626-32. · 0.33 Impact Factor
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ABSTRACT: Some observations in man and experimental animals have demonstrated that casein decreases intestinal transit speed. However, its effects on intestinal motility have not been studied previously in a systematic fashion. The aim of this work was to study the temporospatial distribution of small bowel motility before and after the administration of calcium caseinate. Studies were performed in fasting dogs using 6 catheters perfused with a pneumo-hydraulic system. After the administration of 300 ml of a 10% solution of calcium caseinate, a global decrease in motor activity was observed, specially of grouped propulsive contractions, they were reduced in 64.9 to 19.5%. On the contrary, a significative increase, in 1.4 to 22%, of individual wave, non propulsive motor activity was observed. These quantitative changes in contractions, specially in their organization and temporo-spatial distribution, may be responsible for the decrease in intestinal transit after the administration of casein.
Revista medica de Chile 11/1992; 120(10):1102-5. · 0.33 Impact Factor
