Satoshi Kato

Teikyo University Hospital, Edo, Tōkyō, Japan

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Publications (18)10.91 Total impact

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    ABSTRACT: We report a case of well-differentiated fetal adenocarcinoma (WDFA) of the lung, with emphasis on dynamic CT (computed tomography) findings. The patient was a 38-year-old woman who was found to have a mass in the left upper lung field in chest radiograph screening. Chest radiograph showed a 5.5 cm well-defined mass in the left upper lung field. CT revealed a well-circumscribed mass measuring 5.5 × 5.5 × 5.0 cm with a lobulated margin in the left upper lobe. Intratumoral enhancing vasculature was noted in the early phase of dynamic CT. In the delayed phase, persistent and plateau enhancement was seen. The tumor also had consistently unenhanced areas, suggesting the presence of necrosis. Left upper lobectomy with mediastinal lymph node dissection was performed. The pathology specimen contained tubular glands consisting of non-ciliated columnar cells with areas of solid nests of epithelial cells with weakly eosinophilic cytoplasm (morule) mimicking fetal lung tissue. The tumor was moderately vascularized with areas of comedo necrosis; the stroma was relatively scanty. Final pathological diagnosis was WDFA with left hilar lymph node metastasis (stage T2bN1M0). This is the first report of dynamic CT findings of WDFA, a rare lung tumor. Although these findings are non-specific, they well reflected the pathological characteristics of this tumor.
    Japanese journal of radiology 10/2012; · 0.73 Impact Factor
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    ABSTRACT: To compare the diagnostic accuracy of contrast-enhanced computed tomography (CE-CT), contrast-enhanced ultrasonography (CE-US), superparamagnetic iron oxide-enhanced magnetic resonance imaging (SPIO-MRI), and gadoxetic acid-enhanced MRI (Gd-EOB-MRI) in the evaluation of colorectal hepatic metastases. In all, 111 patients with colorectal cancers were enrolled in this study. Of the 112 metastases identified in 46 patients, 31 in 18 patients were confirmed histologically and the remaining 81 in 28 patients were confirmed by follow-up imaging. CE-CT, CE-US, SPIO-MRI, and Gd-EOB-MRI were evaluated. Mean (of three readers, except for CE-US) area under the receiver operating characteristic curve (A(z) ), sensitivities, and positive predictive values (PPV) were calculated. Each value was compared to the others by variance z-test or chi-square test with Bonferroni correction. For all lesions, mean A(z) and sensitivity of Gd-EOB-MRI (0.992, 95% [56/59]) were significantly greater than those of CE-CT (0.847, 63% [71/112]) and CE-US (0.844, 73% [77/106]). For lesions ≤1 cm, mean A(z) and sensitivity of Gd-EOB-MRI (0.999, 92% [22/24]) were significantly greater than those of CE-CT (0.685, 26% [13/50]) and CE-US (0.7, 41% [18/44]). Mean A(z) (95% CI) of SPIO-MRI for all lesions (0.966 [0.929-0.987]) and lesions ≤ 1 cm (0.961 [0.911-0.988]) were significantly greater than those of CE-CT and CE-US. Mean sensitivity of SPIO-MRI for lesions ≤1 cm (63%, 26/41) was significantly greater than that of CE-CT. Gd-EOB-MRI and SPIO-MRI were more accurate than CE-CT and CE-US for evaluation of liver metastasis in patients with colorectal carcinoma.
    Journal of Magnetic Resonance Imaging 08/2011; 34(2):326-35. · 2.57 Impact Factor
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    ABSTRACT: The aim of this study was to determine a standard deviation (SD) that most reduces the radiation dose without sacrificing the diagnostic accuracy of thin-section computed tomography (CT) for clinical use. A total of 120 patients were examined by multidetector CT. They were assigned to one of four SD groups: 8, 9, 11, and 12. Each SD group consisted of 30 patients. The CT images of the same patients with SD10 that had formerly been examined were used for comparison. Two radiologists independently evaluated the degrees of image noise and diagnostic acceptability of the pulmonary diseases using a point score grading system. We compared the scores between each SD and the SD10 group. Generally, image noise was significantly more prominent in the higher-SD groups. The mean score of diagnostic acceptability was significantly lower in the SD12 group (4.2 ± 1.6) than in the SD10 group (4.6 ± 1.1) group (P < 0.001), whereas no difference was present between the SD8 (4.9 ± 0.7), SD9 (4.8 ± 1.0), and SD11 (4.4 ± 1.5) groups and the SD10 group (4.7 ± 1.1, 4.6 ± 1.4, 4.6 ± 1.1, respectively). Thin-section CT with SD12 is not acceptable. SD11 seems to be the setting with the lowest radiation dose while providing acceptable imaging quality for pulmonary thin-section CT.
    Japanese journal of radiology 07/2011; 29(6):405-12. · 0.73 Impact Factor
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    ABSTRACT: PURPOSE To compare the diagnostic accuracy of contrast-enhanced ultrasonography (CE-US), contrast-enhanced CT (CE-CT), superparamagnetic iron oxide-enhanced MRI (SPIO-MRI), and gadoxetic acid-enhanced MRI, in the evaluation of colorectal hepatic metastases. METHOD AND MATERIALS One hundred and one patients with colorectal cancers were enrolled in this retrospective study. Of the 112 metastases identified, 31 were confirmed histologically and the remaining 81 were confirmed by follow-up imaging. CE-US, SPIO-MRI, gadoxetic acid enhanced-MRI, and CE-CT images were evaluated. Lesions were classified into 3 groups: 1) all lesions, 2) lesions ≤ 10 mm, and lesions >10 mm. The receiver operating characteristic (ROC) analysis was performed and the area under ROC curve (Az), sensitivities, specificities, positive predictive values and negative predictive values were calculated. RESULTS For all lesions, sensitivities and negative predictive values for gadoxetic acid enhanced-MRI (95% (56/59), 97% (103/106)) were significantly greater than those for CE-CT (63% (71/112), 84% (208/249)) CE-US (73% (77/106), 80% (115/144)), and SPIO-MRI (80% (73/91), 84% (94/112)). Az value for gadoxetic acid enhanced-MRI (0.992) was significantly higher than those for CE-CT (0.847) and CE-US (0.843). For lesions ≤ 10 mm, sensitivities and negative predictive values for gadoxetic acid enhanced-MRI (92% (22/24), 98% (90/92)) were significantly greater than those for CE-CT (26% (13/50), 82% (170/207)) CE-US (41% (18/44), 80% (101/127)) and SPIO-MRI (63% (26/41), 85% (82/97)). Az value for Gd-EOB-DTPA-MRI (0.999) was significantly higher than those for CE-CT (0.685) and CE-US (0.7). For lesions > 10 mm, there was no significant difference between all modalities. CONCLUSION gadoxetic acid enhanced-MRI was the most reliable modality for evaluation of liver metastasis in patients with colorectal carcinoma. CLINICAL RELEVANCE/APPLICATION Gadoxetic acid enhanced-MRI was the most reliable modality for evaluation of liver metastasis and should be used for preoperative evaluation in patients with colorectal carcinoma .
    Radiological Society of North America 2010 Scientific Assembly and Annual Meeting; 12/2010
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    ABSTRACT: The aim of this study was to characterize computed tomography (CT) manifestations of local recurrence after stereotactic body radiation therapy (SBRT) for stage I non-small-cell lung cancer (NSCLC). A total of 27 stage I NSCLC patients who were treated with SBRT, including 5 patients with local recurrence, were retrospectively analyzed for serial CT examinations. A bulging margin appeared in 4 of the 5 cases (80%) with local recurrence and 1 of 22 cases (5%) without local recurrence. Air bronchograms were seen in 3 of 5 cases with local recurrence and 21 of 22 cases without local recurrence, but they subsequently disappeared in all 3 cases (100%) with local recurrence and in 4 of the 21 cases (19%) without local recurrence. Ipsilateral pleural effusion was observed in all 5 cases (100%) with local recurrence and in 5 of 22 cases (22%) without local recurrence. The opacity increased in size even after 12 months from the completion of SBRT in cases with local recurrence, whereas it decreased or did not change in size in cases without recurrence. Local recurrence should be suspected on CT when there was (1) a bulging margin, (2) disappearance of air bronchograms, (3) appearance of pleural effusion, or (4) increase in the abnormal opacity after 12 months.
    Japanese journal of radiology 05/2010; 28(4):259-65. · 0.73 Impact Factor
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    ABSTRACT: The aim of this study was to evaluate thinsection computed tomography (CT) and fluorodeoxyglucose positron emission tomography (FDG-PET) findings of localized pulmonary mucinous bronchioloalveolar carcinomas (BACs). From February 2000 to February 2009, there were seven patients with pulmonary localized mucinous BACs that were pathologically confirmed in the surgical specimens. Their CT findings were assessed regarding location, extent (percent) of groundglass opacity (GGO), margin characteristics, and the presence of air-containing spaces and contractive changes. We evaluated the presence of the "angiogram sign" in the patients who underwent enhanced CT. The maximum standardized uptake value (SUVmax) on FDG-PET was measured in four cases. All tumors were located in the lower lobes. The percentages of GGOs ranged from 0% to 70% (average 20%). The tumor margins were well defined in five cases and ill-defined in two cases. Air-containing spaces were seen in all cases. Evidence of contractive change was seen in two of the seven cases. The angiogram sign was identified in one of five patients who underwent enhanced CT. The SUVmax on FDG-PET ranged from 0.93 to 1.97 (mean 1.53). The imaging features of localized mucinous BACs include solid or partly solid attenuation, the presence of air-containing spaces, lack of contractive changes, and lower lobe predominance. Additionally, the SUVmax is markedly low on FDG-PET.
    Japanese journal of radiology 05/2010; 28(4):251-8. · 0.73 Impact Factor
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    ABSTRACT: To evaluate the relationship between SUVmax of primary lung cancers on FDG-PET and lymph node metastasis. The subjects were a total of consecutive 66 patients with lung cancer who were examined by FDG-PET and subsequently underwent surgery between October 2004 and January 2008. There were 41 males and 25 females, ranging in age from 45 to 83 years with an average of 68 years. The pathological subtypes of the lung cancers consisted of 49 adenocarcinomas, 11 squamous cell carcinomas, 2 adenosquamous carcinoma, 1 large cell carcinoma, 1 small cell carcinoma, 1 pleomorphic carcinoma and 1 mucoepidermoid carcinoma. We statistically compared (1) the mean SUVmax of lung cancer between the groups with and without lymph node metastasis (2) the frequency of lymph node metastasis between higher and lower SUVmax of lung cancer groups that were classified by using the median SUVmax of lung cancer, and (3) evaluated the relationship between the SUVmax of lung cancer and frequency of lymph node metastases, and (4) correlations between the SUVmax of lung cancer and number of the metastatic lymph nodes and pathological n stages. The difference in the average of the SUVmax of lung cancer between the cases with and without lymph node metastases was statistically significant (p = 0.00513). Lymph node metastasis was more frequently seen in the higher SUVmax of lung cancer group (17/33, 52%) than in the lower SUVmax of lung cancer group (7/33, 21%) with a statistically significant difference. There was no lymph node metastasis in lung cancers with an SUVmax of lung cancer less than 2.5, and lung cancers with an SUVmax of lung cancer more than 12 had a 70% frequency of lymph node metastasis. There were moderate correlations between SUVmax of lung cancer, and the number of the metastatic lymph nodes (gamma = 0.404, p = 0.001) and pathological n stage (gamma = 0.411, p = 0.001). The likelihood of lymph node metastasis increases with an increase of the SUV of a primary lung cancer.
    Annals of Nuclear Medicine 05/2009; 23(3):269-75. · 1.41 Impact Factor
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    ABSTRACT: To compare diagnostic capability of preoperative N-staging of lung cancer between thin-section CT of the mediastinum and FDG PET, and 5mm slice thickness CT. The subjects were 34 patients with lung carcinoma who were examined by both CT and PET, and subsequently underwent surgery between May 2005 and January 2007. CT was carried out with a 16 detector row helical CT scanner. The raw data were reconstructed into 5 mm slice thickness and 1mm slice thickness (thin-section CT). A total of 251 lymph node stations were retrospectively assessed for the presence of lymph node metastasis with thin-section CT, 5 mm CT and PET. In the interpretations of thin-section CT and 5 mm CT, we employed multi-criteria as follows: nodular calcification and intranodal fat as benign criteria, and short-axis diameter more than 10 mm (size criterion), focal low density other than fat, surrounding fat infiltration and convex margin in hilar lymph nodes, as malignant criteria. On PET, maximum standardized uptake value (SUVmax) of 2.5 or more was used as the criterion of malignancy. Sensitivity and specificity were compared between these examinations using McNemar test. Sensitivities and specificities of thin-section CT, 5 mm CT and PET were 25%, 25%, 25%, and 97%, 94%, 98%, respectively. The statistical analysis revealed that the specificity of 5 mm CT was significantly lower than those of thin-section CT (p=0.039) and PET (p=0.006), while no difference was present between thin-section CT and PET. Thin-section CT of the mediastinum using multiple criteria was comparable to PET in preoperative N-staging of lung cancer.
    European journal of radiology 03/2009; 73(3):510-7. · 2.65 Impact Factor
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    ABSTRACT: This study aimed to evaluate the validity of 0.5-mm thin-section computed tomography (CT) for the assessment of pulmonary nodular lesion in comparison with 1-mm CT. A total of 38 focal lesions from 30 patients, which were scanned with 0.5- and 1.0-mm collimation, were evaluated regarding the extent of ground-glass opacity (GGO) and well-defined margin, and the presence of pleural indentation, spicula, and internal air density. The frequency of each finding was statistically compared between 0.5- and 1-mm CT using the McNemar test. No statistically significant difference was observed between 0.5- and 1-mm CT for each finding. The use of 0.5-mm CT is not justified if the original collimation of multi-detector row CT is near 1 mm.
    Clinical imaging 01/2009; 33(1):11-4. · 0.73 Impact Factor
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    ABSTRACT: PURPOSE The purpose of this study was to determine when delayed scan of 18F-FDG-PET is effective in the differentiation between benign and malignant pulmonary nodules. METHOD AND MATERIALS The subjects were 405 patients (429 pulmonary nodules) that were diagnosed histologically or clinically based on follow-up CT; the nodules that were decreased in size, or unchanged for more than 24 months were considered as benign. All patients received PET scans at 60 min (early scan) and 120 min (delayed scan) after injection of FDG. The maximum standardized uptake values (SUV) were measured and the retention indexes were calculated by the following formula: RI=(delayed SUV - early SUV)/early SUV X 100%. The pulmonary nodules were classified into the three groups by early SUV(eSUV) (eSUV<2.0, 2.0≦eSUV<3.5, 3.5≦eSUV) and the mean RIs were compared between malignant and benign nodules. We evaluated the diagnostic ability of pulmonary nodules when using the combined criteria of eSUV and RI in comparison with that of eSUV alone. RESULTS There were 345 malignant nodules and 74 benign nodules. The mean RIs of all malignant and benign nodules were 26.4±17.7 and 19.4±27.7(p<0.05), respectively. The results of comparison of the mean RIs between malignant and benign nodules in each eSUV group were as follows: eSUV<2.0; 11.4±21.1 and 21.3±36.7(p=0.19), 2.0≦eSUV<3.5; 29.8±19.0 and 10.8±19.6(p<0.01), 3.5≦eSUV; 28.9±22.6 and 26.0±16.7(p=0.44), respectively. A statistically significant difference was seen only in 2.0≦eSUV<3.5 group. When the cut-off value of eSUV as the criterion of malignancy was set at 2.5 and 3.0, the sensitivities, specificities, and accuracies were 80.2%, 55.4%, and 76.0% (eSUV≧2.5), 76.3%, 66.2%, and 74.6% (eSUV≧3.0), respectively. If the criteria of malignancy were defined as eSUV≧3.5 or 2.0≦eSUV<3.5 with a RI of 20% or more, the sensitivity, specificity, and accuracy were 82.3%, 58.1%, and 78.1%. This criteria showed higher sensitivity and accuracy than those using eSUV alone. CONCLUSION When the eSUV of pulmonary nodules ranged from 2.0 to 3.5, addition of delayed phase scan has a potential impact on improving the accuracy of the diagnosis of pulmonary nodules. CLINICAL RELEVANCE/APPLICATION Addition of delayed phase scan can improve accuracy of the diagnosis of pulmonary nodules have eSUV ranged from 2.0 to 3.5.
    Radiological Society of North America 2008 Scientific Assembly and Annual Meeting; 12/2008
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    ABSTRACT: PURPOSE The purpose of this study was to evaluate the usefulness of delayed scan of 18fluorine fluorodeoxyglucose positron emission tomography (18F-FDG PET) for the diagnosis of lymph node metastasis in non-small cell lung cancer (NSCLC). METHOD AND MATERIALS The subjects were 82 patients with NSCLC (52 adenocarcinomas, 24 squamous cell carcinomas, 6 other lung carcinomas), who were underwent surgical nodal staging. A total of 462 lymph node stations (242 mediastinal lymph node stations and 220 hilar lymph node stations) were evaluated histologically for the presence or absence of metastasis. All patients received PET scan at 60 min (early scan) and 120 min (delayed scan) after injection of 18F-FDG. The maximum standardized uptake values (SUV) of their lymph node stations were measured at early and delayed phase. For the lymph node stations that showed clear accumulation (defined as SUV of 1.5 or more at early phase), we calculated the retention index (RI=[delayed SUV - early SUV] / early SUV X 100%). In addition, we evaluated the diagnostic ability of lymph node metastasis when using the combined criteria of early SUV and RI in comparison with that of early SUV alone. RESULTS Fifty-four lymph node stations (18 mediastinal lymph node stations and 36 hilar lymph node stations) had proven metastases histologically. The mean RIs of the lymph node stations were as follows; 18.36% for mediastinal lymph node stations with metastasis, -1.96% without metastasis; 16.93% for hilar lymph node stations with metastasis; -0.50% without metastasis. There was a statistically significant difference (p<0.05) in mean RI between the lymph node stations with and without metastasis of each location. When the cut-off value of SUV at early scan as the criterion of malignancy was set at 2.5 or 2.0, the sensitivities, specificities, and accuracies were 39.6%, 92.9% and 87.2% (SUV>2.5), 61.1%, 79.4% and 77.3% (SUV>2.0), respectively. If RI more than 10% was added into the criterion, the sensitivities, specificities, and accuracies became 34.0%, 97.8% and 90.5% (SUV>2.5), 53.7%, 95.6% and 90.7% (SUV>2.0), respectively. CONCLUSION Metastatic lymph nodes have a higher RI than non-metastatic ones. The combined criteria of early SUV and RI can improve the accuracy of the diagnosis of lymph node metastasis in NSCLC. CLINICAL RELEVANCE/APPLICATION Addition of delayed scan can improve accuracy of the diagnosis of the lymph node metastasis in NSCLC
    Radiological Society of North America 2008 Scientific Assembly and Annual Meeting; 12/2008
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    ABSTRACT: PURPOSE To evaluate the relationship between SUVmax of primary lung cancers on FDG-PET and lymph node metastasis. METHOD AND MATERIALS The subjects were a total of consecutive 66 patients with lung cancer who were examined by FDG-PET and subsequently underwent a surgery between October 2004 and January 2008. There were 41 males and 25 females, ranging in age from 45 to 83 years old with an average of 68 years.The pathological subtypes of the lung cancers were composed of 50 adenocarcinomas, 11 squamous cell carcinomas, 1 large cell carcinoma, 1 small cell carcinoma, 1 pleomorphic carcinoma and 1 mucoepidermoid carcinoma. We statistically compared (1) the frequency of lymph node metastasis between higher and lower SUV groups that were classified by using the median SUV, and (2) evaluated the relationships between the SUVs and frequencies of lymph node metastasis, and (3) correlations between the SUVs and frequencies of lymph node metastasis, number of the metastatic lymph nodes and pathological n stages. RESULTS (1) Lymph node metastasis was more frequently seen in higher SUV group (17/33, 52%) than in lower SUV group (7/33, 21%) with a statistically significant difference. (2) There was no lymph node metastasis in lung cancers with a SUV less than 2.5 and lung cancers with a SUV more than 12 had a 70% frequency of lymph node metastasis. (3) A strong correlation was noted between the SUV groups divided by 5 increments and frequencies of lymph node metastasis (γ=0.971, p=0.001). There were moderate correlations between SUV, and the number of lymph node metastasis(γ=0.404, p=0.001) and pathological n stage(γ=0.411, p=0.001). CONCLUSION As the SUV of a primary lung cancer gets higher, the likelihood of lymph node metastasis increases. CLINICAL RELEVANCE/APPLICATION We might improve accuracy of preoperative N-staging of lung cancer by considering the SUV of the primary lung cancer.
    Radiological Society of North America 2008 Scientific Assembly and Annual Meeting; 12/2008
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    ABSTRACT: This study aimed to evaluate the efficacy of thin-section CT of the mediastinum in the assessment of thoracic lymph nodes in comparison with conventional CT. A total of 193 CT examinations from 193 patients with suspected pulmonary disease were reconstructed into thin-section CT and conventional CT. The appearances of the lymph nodes were assessed and compared between thin-section CT and conventional CT. Intranodal fat was more often detected on thin-section CT than on conventional CT (P<.001). There were no statistically significant differences in the frequencies of inhomogeneous enhancement and bulging margin of the hilar lymph node. Thin-section CT can improve clinical N-staging of lung cancer due to classification of enlarged mediastinal lymph nodes as benign based on identification of intranodal fat.
    Clinical Imaging 01/2007; 31(6):375-8. · 0.65 Impact Factor
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    ABSTRACT: PURPOSE To investigate the capability to detect superficial bladder cancers and recurrences after transurethral resection of bladder tumor (TUR-BT) with diffusion-weighted and high-resolution MR images. METHOD AND MATERIALS 29 MR images of 21 patients underwent TUR-BT for superficial bladder cancers between July 1 2004 and December 31 2005 were included. The All patients were underwent cystoscopy urinary cytodiagnose, and MR imaging before TUR-BT and at regular interval after TUR-BT. Scanning was performed in a 1.5T MRI system (Magnetom Symphony, Siemens). After conventional sequences (sagittal T2w, axial T1w, and axial fat-suppressed T2w), diffusion weighted images (DW; TR/TE 10000/84ms, TI 150ms, b 800, NEX 6,matrix 96×128, FOV 450mm, 5mm-section thickness) were obtained with parallel imaging technique. And high-resolution images (HR) were obtained with 3 dimensional Volumetric Interpolated Breath-hold Examination(3D-VIBE; TR/TE 5/2ms, FA 15, matrix 320×320, 0.7mm-section thickness, FOV 280mm) at 60 second after bolus intravenous injection of gadopentetate dimeglumine (Magnevist). With conventional images, DW, and HR, respectively, two experienced radiologists diagnosed with five degree system whether there were superficial bladder cancers or not. ROC analysis, and the sensitivity and specificity were used for statistical analysis. RESULTS With cystoscopy, 16 cases had superficial bladder cancers or recurrences, and 13 cases had no lesion. Each mean Az value in two readers with HR and with DW was higher than that with conventional images (p<.001). The sensitivity in HR was the highest (84.4%), and the minimum thickness of the cancer detected with HR was 1mm. All of the cancers not detected with HR were carcinoma in situ (CIS). Although the sensitivity in DW was lower than HR, the specificity in DW was the highest (92.3%). CONCLUSION High-resolution MR images supplemented with diffusion weighted images are able to detect superficial bladder cancers and recurrences after TUR-BT except for CIS. CLINICAL RELEVANCE/APPLICATION High-resolution MR images supplemented with diffusion weighted images are able to detect superficial bladder cancers and recurrences after TUR-BT except for CIS.
    Radiological Society of North America 2006 Scientific Assembly and Annual Meeting; 11/2006
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    ABSTRACT: To evaluate the diagnostic ability of multiplanar reformation (MPR) images of the lung in comparison with thin-section source CT images. MPR images were reconstructed for 79 patients with suspected pulmonary disease. Slice thicknesses of source images were 2 mm in 24, 1 mm in 30, and 0.5 mm in 25 cases. The presence of centrilobular nodules, emphysema, bronchiectasis, ground-glass opacity (GGO), consolidation, interstitial thickening, and pulmonary nodule was evaluated on thin-section source images by an experienced chest radiologist to establish gold standards and then subsequently assessed on the MPR images independently by two radiologists. The sensitivity, specificity, and accuracy of each finding were calculated regarding the results of thin-section source images as the gold standards. Accuracy for the detection of findings was also statistically compared among the three groups of different source slice thicknesses using Fisher's exact test. Accuracy for the detection of findings was significantly less (p < 0.05) in 2 mm slice MPR for centrilobular nodule, GGO, and interstitial thickening than in 1 mm or 0.5 mm slice MPR. No statistically significant difference was observed for any of the findings between 0.5 mm and 1 mm slice MPR. Rates of sensitivity, specificity, and accuracy of the MPR images for detection of the findings were 89-100%, 73-95%, and 84-95%, respectively. In comparison with thin-section source images, MPR images are comparably sensitive but not as specific for the detection of findings. When producing MPR images, the slice thickness of source images should be less than 2 mm.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 11/2005; 65(4):378-83.
  • Akitoshi Saito, Tsutomu Araki, Satoshi Kato
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    ABSTRACT: PURPOSE To exam whether T staging of urinary bladder carcinoma is diagnosed confidently with the optional MPR imaging constructed from the high resolution 3D data of the dynamic contrast-enhanced MR imaging with SENSE at the phase when the submucosal layer of urinary bladder is enhanced. METHOD AND MATERIALS The dynamic contrast-enhanced MR imaging (Symphony 1.5T, SIEMENS) of 27 patients (male: female = 20:7, age 35-83) with urinary bladder carcinoma was performed with following parameters from July 2002 to April 2004; 2D fast low-angle shot (2D FLASH, TR180/ TE5/ FA90 matrix 512�256/ slice thickness 8mm/ fat suppression(+)) was performed at 30 second after intravenous injection of 20ml gadopentetate dimeglumine (Magnevist) at the rate of 3ml/ sec, and 3D volumetric interpolated breath-hold examination (3D VIBE, TR5/ TE2/ FA15/ matrix 512�256/ slice thickness 1mm/ fat suppression(+)) with SENSE was performed at 60 second after injection. Two radiologists diagnosed T staging and examined the confidence of each diagnosis in order of the following; 1) 2D images, 2) 3D MPR images same as the plain of 2D images and 3) 3D MPR images of another plain. The positive predicting value (PPV) whether T1 was diagnosed correctly was calculated in each situation. The score of confidence was divided in 0-3 (0: misdiagnosed, 1: obscure, 2: possible, 3: definite), and compared between each two situation. RESULTS The concordance between two radiologists was good (k=.870). Although the PPV in 1) was 75.0%, each PPV in 2) and 3) was more than 90.0%. The confidence in 2) was higher than in 1), and that in 3) was further higher than in 3) (p<.01, Wilcoxon�s rank test). CONCLUSION T staging of urinary bladder cancer was diagnosed more correctly with the images constructed from 3D and 2D data than only with the images constructed from 2D data. And the confidence of the diagnosis was higher with another plain constructed from high resolution 3D data.
    Radiological Society of North America 2004 Scientific Assembly and Annual Meeting; 12/2004
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    ABSTRACT: PURPOSE/AIM The purposes of this exhibit are 1. To provide differential diagnoses of focal areas of GGO on thin-section CT and differential clues between them. 2. To describe the pathological implications of focal areas of GGO 3. To present appropriate multidetector row CT protocols to image focal area of GGO. CONTENT ORGANIZATION Definition of focal areas of GGO Recommended CT protocols for the evaluation of focal GGO Differential diagnoses with differential clues and pathological implications Bronchioloalveolar cell carcinoma (BAC), including its clinical aspects Atypical adenomatous hyperplasia( AAH) Focal pneumonia Focal fibrosis Focal lymphocyte aggregation Multifocal micronodular pneumocyte hyperplasia Infectious bronchiolitis LIP Respiratory bronchiolitis Metastatic calcification Sarcoidosis SUMMARY Major teaching points of this exhibit are 1. Developing appropriate CT protocols is critical for the evaluation of focal areas of GGO. 2. Unique clinical features of BAC that are distinct from those of other lung carcinomas. 3. Key thin-section CT findings of focal areas of GGO that often allow us to make a definitive diagnosis. 4. Relatively characteristic appearances of the diseases showing multifocal GGO.
    Radiological Society of North America 2008 Scientific Assembly and Annual Meeting;
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    ABSTRACT: PURPOSE/AIM 1. To demonstrate the change of follow-up CT appearances of radiation pneumonitis after SRT for stage I NSCLC. 2. To characterize CT manifestations of local recurrence superimposed over radiation pneumonitis afer SRT. CONTENT ORGANIZATION 1. Change of follow-up CT appearances of radiation pneumonitis after SRT for stage I NSCLC 2. The cases of local recurrence 3. Characteristics of CT manifestations of local recurrence superimposed over radiation pneumonitis afer SRT SUMMARY The major teaching point of this exhibit is : Local recurrence of stage I NSCLC after SRT should be suspected on CT when i) appearance of bulging margin, ii) disappearance of air bronchograms, iii) appearance of pleural effusion, or iv) increase in the abnormal opacity after 12 months from the completion of SRT is noted.
    Radiological Society of North America 2006 Scientific Assembly and Annual Meeting;