S Kanda

Kyushu University, Fukuoka-shi, Fukuoka-ken, Japan

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Publications (99)66.72 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: The study goal was to clarify the association between computed tomography (CT) findings, histologic features, and outcome of osteosarcoma of the jaw (OSJ). The CT findings and histologic features of 10 patients with OSJ were retrospectively analyzed. The patients were histopathologically diagnosed to have OSJ. The points analyzed on the CT included the patterns of osteogenesis and any signs of bone destruction. The histologic types were classified according to the 1993 World Health Organization histologic classification of bone tumors. Furthermore, the histologic subtype was classified into the following 3 types: osteoblastic, chondroblastic, and fibroblastic. The grade of the tumor tissue was classified from I to IV. These were compared with the affected jaw site and the outcome of the patients with OSJ. All tumors were classified into the conventional central osteosarcoma histologically. Eight cases were osteoblastic, and 2 cases were chondroblastic. Grade I or II (4 of 5 patients are alive without disease) dominated in the maxilla, but in contrast, grade III or IV (4 of 5 patients are dead of disease or alive with disease) dominated in the mandible. A significant association was seen between the osteogenesis found on the CT images and the outcome, between the grade and the outcome, and between the outcome and the affected jaw site ( P = .02), respectively, in OSJ in this study. However, no significant association was observed between the CT findings and the histologic features in OSJ in this series. The osteogenesis on the CT, grade, and affected jaw site were considered to be prognostic factors in OSJ in this limited series.
    Journal of Oral and Maxillofacial Surgery 04/2005; 63(3):311-8. · 1.28 Impact Factor
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    ABSTRACT: We present 3 cases of Sjögren's syndrome in which multiple sialolithiasis were observed in the parenchyma of the parotid gland. The sonographic examinations showed microliths that were observed as hyperechoic spots. Some of the microliths were accompanied with comet sign, however most of them showed no particular posterior echoes. None of them showed acoustic shadows, which are normally observed in cases with sialolithiasis. We were able to prove that some of the hyperechoic spots observed sonographically in patients with severe Sjögren's syndrome were microliths. Although these multiple microliths are rarely detected, they may exist potentially in higher frequency in patients with severe Sjögren's syndrome.
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 02/2005; 99(1):85-92.
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    ABSTRACT: To clarify the useful findings for determining whether the submandibular mass is intraglandular or extraglandular. Forty-eight patients with swelling of the submandibular region were reviewed. The relationship between the lesion and the submandibular gland and the displacement of the anterior facial vein were analyzed. The accuracy of the predictions based on the relationship between the lesion and the submandibular gland (SMG) was 87% on contrast-enhanced CT (CECT), 85% on CT sialography (CTS), and 91% on MRI. Although the displacement of the facial vein outside the lesion suggested an intraglandular lesion, and inside the lesion suggested an extraglandular lesion, these were not sufficient to differentiate the lesions in 7 out of 23 CECT cases and 4 out of 11 MRI cases. The finding of a relationship between the lesion and the SMG is the most important finding of this study.
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 01/2005; 98(6):721-9.
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    ABSTRACT: The purpose was to illustrate the sonographic changes of tongue cancer after radical radiotherapy. In 24 patients with tongue cancer treated by interstitial brachytherapy (BRT) (uneventful recovery n = 16 , recurrence n = 5, severe soft tissue complication n = 3), follow-up examination were performed and both the margin and the vascular pattern were retrospectively assessed. We basically performed US examination at least once every 3 months after BRT within 1 year during follow-up period. In the healing process, intraoral sonography shows an unclear margin immediately after brachytherapy and a transient increase of the vascularity lasted within 6 months after BRT, followed by a decrease in the vascularity. The large difference in echogenicity between the primary site and the surrounding tissue and the increased difference suggested the possibility of either radiation ulceration or recurrence. Intraoral sonography could depict the sequence changes of the tongue after BRT, and it was thus useful to confirm the clinical findings of either radiation ulcers or recurrence.
    European Journal of Radiology 01/2005; 52(3):246-56. · 2.51 Impact Factor
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    ABSTRACT: ObjectiveTo clarify the useful findings for determining whether the submandibular mass is intraglandular or extraglandular.Study designForty-eight patients with swelling of the submandibular region were reviewed. The relationship between the lesion and the submandibular gland and the displacement of the anterior facial vein were analyzed.ResultsThe accuracy of the predictions based on the relationship between the lesion and the submandibular gland (SMG) was 87% on contrast-enhanced CT (CECT), 85% on CT sialography (CTS), and 91% on MRI. Although the displacement of the facial vein outside the lesion suggested an intraglandular lesion, and inside the lesion suggested an extraglandular lesion, these were not sufficient to differentiate the lesions in 7 out of 23 CECT cases and 4 out of 11 MRI cases.ConclusionThe finding of a relationship between the lesion and the SMG is the most important finding of this study.
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 12/2004;
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    ABSTRACT: The aim of this study was to assess the changes in the power Doppler sonographic findings in patients with oral cancer undergoing chemotherapy and radiotherapy. We performed US examinations on 187 cervical lymph nodes (71 metastatic and 116 reactive nodes) excised from 52 patients before and after preoperative therapy. On Power Doppler images, we calculated the vascular index (VI) and evaluated the vascular pattern. We also assessed the diagnostic power using receiver operating characteristic (ROC) curve analysis. Irradiation caused an increase of the VI and better visualization of the vessels within the lymph node in the reactive nodes; however, in the metastatic nodes, the VI was not significantly different between that before and after irradiation. When the reader observed the images before irradiation, the area under an ROC curve (Az values) observed by B-mode sonography were closely similar to those obtained by B-mode plus power Doppler sonography. With both images before and after irradiation, the Az value obtained by B-mode plus power Doppler sonography was higher than that by B-mode sonography alone. After irradiation, the enhanced Doppler signals contributed to a better visualization of the vessels and a better detection of any vascular abnormalities.
    European Radiology 08/2004; 14(7):1255-62. · 4.34 Impact Factor
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    ABSTRACT: ObjectivesTo construct and analyze perceptibility curves (PCs) according to two different approaches. Material and methodsA test object was used to determine the exposures and exposure differences between the total thickness of the test object and details consisting of holes of increasing depth. Two digital systems were employed to predict PCs according to the two different approaches. One approach defined exposures and exposure differences from dose-response functions, including secondary and scattered radiation. The other defined exposure and exposure differences as calculated transmitted radiation flux from the primary beam behind the test object, excluding secondary and scattered radiation. Integrals of the PCs and of the minuimum perceptible gray-level differences as functions of background gray levels were calculated. The validity of the different types of PCs was analyzed. Another test object was used to predict observer performance for the two systems. ResultsThe integrals of PCs obtained according to the above first-mentioned approach and integrals of gray-level differences as functions of background gray level were equal. The same integrals using the second approach were different. The second approach, however, successfully predicted observer performance for the two systems. ConclusionsOnly the first-mentioned approach gives PCs that are true representations of psychophysical properties. The second approach may, however, be employed to predict observer performance when different radiographic systems are employed.
    Oral Radiology 05/2004; 19(1):38-48. · 0.17 Impact Factor
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    ABSTRACT: To compare psychophysical properties of two intraoral films and three digital systems using the perceptibility curve (PC) test. A test object was used to determine the exposures and exposure differences between the total thickness of the test object and details consisting of holes of increasing depth. The PCs for the two intraoral films, UltraSpeed and EktaSpeed Plus, were constructed employing exposure and exposure differences from dose response functions. Integrals of the PCs were calculated to obtain the psychophysical properties of the two films. Psychophysical properties of the two films were compared with those of the three digital systems published previously (CDR, Dixel and Digora). The PC for the EktaSpeed Plus showed a slightly higher peak than that for the UltraSpeed. Available exposure ranges were comparable. The PC for the EktaSpeed Plus was shifted to the left of the exposure axis indicating its higher sensitivity as compared with UltraSpeed. All three digital systems had narrower but higher peaks compared with the films. The integrals for the digital systems were considerably larger than those for the two film types. All the three digital systems have superior psychophysical properties compared with the two tested films.
    Dentomaxillofacial Radiology 04/2004; 33(2):98-102. · 1.27 Impact Factor
  • Journal of Oral and Maxillofacial Surgery 02/2004; 62(1):107-11. · 1.28 Impact Factor
  • Journal of Oral and Maxillofacial Surgery - J ORAL MAXILLOFAC SURG. 01/2004; 62(1):107-111.
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    ABSTRACT: We sought to clarify the correlation among a computed tomography (CT) or a panoramic radiography (PR) pattern of bone destruction, a histologic pattern of bone destruction, and a mode of invasion in carcinoma of the mandibular gingiva. CT images, panoramic radiographs, and decalcified, hematoxylin-eosin-stained preparations of the excised mandibular bone of 62 patients with carcinoma of the mandibular gingiva were retrospectively evaluated. Each computed tomograph, panoramic radiograph, and the histologic pattern of bone destruction was classified as 1 of 5 types: erosive, erosive and partly mixed, mixed, mixed and partly invasive, or invasive. The mode of invasion of the tumor was also assessed with a hematoxylin-eosin-stained preparation of the initial biopsy specimen. The relationships among the CT pattern, the PR pattern, the histologic pattern of bone destruction, and the mode of invasion of the tumor were statistically analyzed by using the Spearman rank correlation test. The CT pattern (P =.005) and the PR pattern (P =.003) were significantly correlated with the histologic pattern with respect to the bone destruction. The CT pattern (P =.996), the PR pattern (P =.997), and the histologic pattern (P =.521) of bone destruction were not correlated with the mode of invasion seen in the biopsy specimen. The CT pattern and the PR pattern of bone destruction reflect the histologic pattern of bone destruction caused by carcinoma of the mandibular gingiva but are not associated with the mode of invasion of the tumor.
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 01/2004; 96(6):774-82.
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    ABSTRACT: ObjectiveTo evaluate quantitatively the long-term changes in alveolar bone around toothimplant connections using a digital subtraction technique. Study designEighteen cases where implants were embedded and connected to the mandibular molar teeth or to each other were analyzed. Digital substraction images were obtained from baseline and follow-up digitized radiographs. These images were quantitatively analyzed by two methods, “area analysis” and “density analysis”. Calcification and decalcification around the abutment teeth and implants were quantitatively evaluated. In two cases involving abutment teeth with a considerable loss of supporting periodontal tissues, the treatment process used was thoroughly evaluated to study how alveolar bone regeneration occurs in such patients. ResultsNo decalcification areas were detected in any of the cases. Calcification around abutment teeth, implants, or both was observed in 11 (92%) of 12 cases. In the remaining 6 cases, in which implants were connected to each other, calcification was observed around the implants in 4 cases (67%). In two cases where long-term quantitative analysis was possible, calcification started 4 years after placement of connected crowns. ConclusionConnection of osseo-integrated implants to abutment teeth may be an effective treatment for patients suffering from periodontal disease.
    Oral Radiology 01/2004; 19(1):28-37. · 0.17 Impact Factor
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    ABSTRACT: Without Abstract
    Oral Radiology - ORAL RADIOL. 01/2004; 19(1):89-96.
  • Journal of Oral and Maxillofacial Surgery 11/2003; 61(10):1233-6. · 1.28 Impact Factor
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    ABSTRACT: To construct perceptibility curves (PCs) for given calibration settings in order to define psychophysical properties of the Digora storage phosphor system and to evaluate the effects of automatic exposure correction (AEC) on the PCs. The Digora system was calibrated at two exposures, 80 microC kg(-1) (high calibration) and 40 microC kg(-1) (low calibration). Since the grey levels displayed in the radiographs are adjusted by AEC, dose-response functions at high calibration were obtained using AEC on and off modes. The dose-response function at low calibration was obtained with AEC off. The PC at each experimental setting was calculated using known physical parameters of the system and the performance of the average observer used in a previous study. In addition, PCs were also constructed using transmitted radiation flux behind the test object calculated from the attenuation coefficient in order to study observer and system performance. PCs obtained under these conditions were compared. The PC using calculated transmitted radiation flux behind the test object showed a wide plateau at the peak owing to AEC, while the PC obtained by a modified approach showed a higher but narrower peak. There were no differences between the two PCs using AEC on and off modes when the PCs were constructed using a modified approach. There were no differences between the two PCs obtained at high and low calibration settings or between the three PCs obtained with AEC on except for the position along the exposure axis. Psychophysical properties of the Digora system may be determined if we employ registered exposures from a dose-response function with AEC off under a given calibration setting. Under these circumstances the shape and height of the PCs will be unchanged irrespective of the AEC mode.
    Dentomaxillofacial Radiology 06/2003; 32(3):191-7. · 1.27 Impact Factor
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    ABSTRACT: We sought to evaluate the diagnostic efficacy of computed tomography (CT) images in the differentiation between intraosseous malignant tumors and osteomyelitis spreading into the masticator space. A retrospective evaluation was carried out by using CT images from 12 patients with intraosseous malignant tumors and 9 patients with osteomyelitis involving the masticator space and accompanying mandibular bone destruction. The following CT observations are discussed: (1) bone destruction pattern subdivided into spotty, gross, or permeative; (2) cortical bone expansion; (3) diffuse osteosclerotic changes; (4) periosteal reaction; (5) masticator muscle involvement; (6) enlargement of the facial muscle; and (7) attenuation in the subcutaneous adipose tissue. The pattern of permeative bone destruction, cortical bone expansion, and the enlargement of both the masseter and medial pterygoid muscles were all observed in patients with malignant tumors. In contrast, diffuse sclerotic change and a periosteal reaction were significant observations in patients with osteomyelitis. The efficacy of CT in establishing a differential diagnosis of malignant tumors or osteomyelitis is supported by this study.
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 05/2003; 95(4):503-9.
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    ABSTRACT: Most jaw muscles are complex, multipennate with multiple components. The morphologic heterogeneity of masticatory muscles reflects their functions. We hypothesized that the volume of masticatory muscles changes between jaw closing and opening, and that there is a difference in the volume change among the muscles. Magnetic resonance images of the entire head were obtained in ten normal young adult subjects before and after maximum jaw opening. The volume changes of the masseter, medial, and lateral pterygoid muscles were measured. Only slight changes were seen in the masseter and medial pterygoid muscles. The lateral pterygoid muscle, however, significantly decreased its volume during jaw opening. The results provide normative values of muscle volume in living subjects, and suggest that the volume changes differ among jaw muscles.
    Journal of Dental Research 07/2002; 81(6):428-32. · 3.83 Impact Factor
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    ABSTRACT: We describe a case of lymphoepithelial lesion of the parotid gland, also known as salivary lymphoepithelial lesion. Lymphoepithelial lesions are usually seen in conjunction with autoimmune disease of the salivary glands and these lesions do not always remain benign. Our case consisted of two masses that had different imaging features. Moreover, we could investigate the changes of the size and internal architecture on imaging due to the postponement of surgical intervention on the masses. At review 6 months later, the size of the masses had increased. The aims of this paper were to: (1) investigate the contribution of gray-scale sonography, power Doppler sonography, magnetic resonance imaging, and computed tomography to the diagnosis; and (2) consider the appropriate imaging modality to follow-up this case to monitor for recurrence or malignant transformation.
    Dentomaxillofacial Radiology 06/2002; 31(3):198-203. · 1.27 Impact Factor
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    ABSTRACT: Experimental models of lymph node metastasis were developed for Doppler sonography. Cervical lymph node (LN) metastasis was induced by the implantation of a VX-2 tumor on the oral floor of 10 rabbits. Twenty metastatic LNs were observed weekly by power Doppler sonography, and the presence of an avascular area and the peripheral vessels were evaluated. The time-averaged maximum velocity (TAMx) at the hilum was also measured. The percentage of the metastatic LNs presenting with an avascular area increased over time. The peripheral vessels were detected in 14 of 20 LNs. The peak time of the TAMx significantly correlated to that of the initial detection of the avascular area. In the beginning, metastatic LNs were depicted as hypervascular structures while the TAMx at the hilum increased. Later, an avascular area was detected and the TAMx at the hilum decreased, which resulted in a blood supply to the node from the peripheral vessels.
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 04/2002; 93(3):350-7.
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    ABSTRACT: To construct Perceptibility Curves (PCs) for contrast-enhanced digital intraoral radiographs. Radiographs of a test object having holes of increasing depths were exposed using three digital systems, the CDR (Schick Technologies, Long Island, NY, USA), the Dixel (J Morita MFG, Kyoto, Japan) and the Sens-A-Ray (Regam Medical Systems, Sundsvall, Sweden). The radiographs were contrast-enhanced and PCs constructed in the conventional way using 10 observers. Predicted PCs were calculated and compared with observer data. The PCs showed that contrast enhancement is effective for the perception of small contrast details, especially in the low exposure range. Predicted PCs demonstrated excellent agreement with observer data. Contrast enhancement should be advantageous in digital radiography. The effects of contrast enhancement on PCs may be predicted without previous knowledge of observer performance.
    Dentomaxillofacial Radiology 08/2001; 30(4):219-25. · 1.27 Impact Factor

Publication Stats

659 Citations
66.72 Total Impact Points

Institutions

  • 1986–2005
    • Kyushu University
      • Faculty of Dental Science
      Fukuoka-shi, Fukuoka-ken, Japan
  • 2003
    • Sapporo Medical University
      • Department of Oral Surgery
      Sapporo, Hokkaidō, Japan
  • 1994–2001
    • Fukuoka University
      Hukuoka, Fukuoka, Japan