Publications (2)2.19 Total impact
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Article: Linkage mapping of the rat poly(ADP-ribose) glycohydrolase (Parg) gene to chromosome 16.
Experimental Animals 08/1999; 48(3):217-8. · 0.92 Impact Factor -
Article: The human poly(ADP-ribose) glycohydrolase maps to chromosome 10q11.23-21.1 by fluorescence in situ hybridization.
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ABSTRACT: Poly(ADP-ribose) glycohydrolase (PARG) digests poly(ADP-ribose), which is synthesized by poly(ADP-ribose) polymerase (PARP) after DNA damage. We mapped the human poly(ADP-ribose) glycohydrolase gene to chromosome 10q11.23-21.1 by fluorescence in situ hybridization analysis. Since chromosomal rearrangements in thyroid papillary carcinoma and loss of heterozygosity in glioblastoma are frequently observed in this region, genetic alteration of PARG could be implicated in these diseases.Human Cell 01/1999; 11(4):243-6. · 1.27 Impact Factor