D. Langford

Publications (3)8.7 Total impact

• Article: Dermoscopy of scalp tumours: a multi-centre study conducted by the international dermoscopy society.

  I Stanganelli, G Argenziano, F Sera, A Blum, F Ozdemir, I K Karaarslan, D Piccolo, K Peris, H Kirchesch, R Bono, [......], S Astorino, A M Manganoni, J-Y Gourhant, J Keir, J M Grichnik, G Fumo, H Dong, A M Sortino Rachou, G Ferrara, I Zalaudek
  [show abstract] [hide abstract]
  ABSTRACT: Little is known about the dermoscopic features of scalp tumours. Objective  To determine the dermoscopic features of scalp tumours. Retrospective analysis of dermoscopic images of histopathologically diagnosed scalp tumours from International Dermoscopy Society members. A total of 323 tumours of the scalp from 315 patients (mean age: 52 years; range 3-88 years) were analysed. Scalp nevi were significantly associated with young age (<30 years) and exhibited a globular or network pattern with central or perifollicular hypopigmentation. Melanoma and non-melanoma skin cancer were associated with male gender, androgenetic alopecia, age >65 years and sun damage. Atypical network and regression were predictive for thin (≤1 mm) melanomas, whereas advanced melanomas (tumour thickness > 1 mm) revealed blue white veil, unspecific patterns and irregular black blotches or dots. The data collected provide a new knowledge regarding the clinical and dermoscopy features of pigmented scalp tumours.
  Journal of the European Academy of Dermatology and Venereology 07/2011; 26(8):953-63. · 2.98 Impact Factor
• Article: Dermoscopy key points: recommendations from the international dermoscopy society.

  J Bowling, G Argenziano, A Azenha, J Bandic, R Bergman, A Blum, H Cabo, A Di Stephani, J Grichnik, A Halpern, [......], S Puig, H Rabinovitz, P Rubegni, T Saida, M Scalvenzi, S Seidenari, H P Soyer, M Tanaka, I Zalaudek, R P Braun
  Dermatology 02/2007; 214(1):3-5. · 2.05 Impact Factor
• Article: Three-point checklist of dermoscopy: an open internet study.

  I Zalaudek, G Argenziano, H P Soyer, R Corona, F Sera, A Blum, R P Braun, H Cabo, G Ferrara, A W Kopf, D Langford, S W Menzies, G Pellacani, K Peris, S Seidenari
  [show abstract] [hide abstract]
  ABSTRACT: In a pilot study, the three-point checklist of dermoscopy has been shown to represent a valid and reproducible tool with high sensitivity for the diagnosis of skin cancer in the hands of a small group of nonexperts. To re-evaluate these preliminary results in a large number of observers independently from their profession and expertise in dermoscopy. The study was conducted via the internet to provide worldwide access for participants. After a short web-based tutorial, the participants evaluated dermoscopic images of 165 (116 benign and 49 malignant) skin lesions (15 training and 150 test lesions). For each lesion participants scored the presence of the three-point checklist criteria (asymmetry, atypical network and blue-white structures). Kappa values, odds ratios, sensitivity, specificity and likelihood ratios were estimated. Overall, 150 participants joined the study. The three-point checklist showed good interobserver reproducibility (kappa value: 0.53). Sensitivity for skin cancer (melanoma and basal cell carcinoma) was 91.0% and this value remained basically uninfluenced by the observers' professional profile. Only 20 participants lacking any experience in dermoscopy performed significantly more poorly, but the sensitivity was still remarkably high (86.7%) when considering that they were untrained novices in dermoscopy. The specificity was 71.9% and was significantly influenced by the profession, with dermatologists performing best. Our study confirms that the three-point checklist is a feasible, simple, accurate and reproducible skin cancer screening tool.
  British Journal of Dermatology 04/2006; 154(3):431-7. · 3.67 Impact Factor