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R Palo,
L Capraro, R Hanhela,
M Koivuranta,
L Nikkinen,
M Salmenperä,
I Salonen,
S Sjövall,
A Tienhaara,
M Vähämurto,
T Mäki
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ABSTRACT: Descriptive information on platelet (PLT) recipients, particularly during surgery, is limited. A description of the current epidemiology of PLT-transfused patients is required to optimize platelet transfusion care and to follow trends in PLT use. In 2004 and 2005, information was combined from several computerized medical systems. Participating hospitals (9 hospital districts of 21) handled approximately 64% of annual Finnish hospital admissions. A total of 6321 adult patients were transfused with 37,761 PLT products. Most PLT products (43.1%) were transfused to patients suffering from haematological malignancies. Only 1.0% of all surgical patients received PLTs (53.8% of PLT recipients and 35.8% of transfused PLTs). The most common single operation connected with PLT transfusion was coronary artery bypass while 27.1% of surgery-related PLTs were given to patients having an operation involving the digestive system or spleen. Only 36.4% of all PLT-transfused (operated and conservatively treated) patients were discharged directly home; in-hospital mortality was 9.5%. PLTs were given 40 products per 1000 hospital admissions requiring an operation in 2004, and 38 products in 2005. Perioperative PLT use is slightly decreasing in adult patients. As a single-operation type, coronary artery bypass patients receive most of the PLT products and have experienced no decline in PLT use over the years. Overall, PLT recipients have high in-hospital mortality.
Transfusion Medicine 09/2009; 20(1):30-7. · 1.14 Impact Factor
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R Palo,
T Ali-Melkkilä, R Hanhela,
V Jäntti,
T Krusius,
E Leppänen,
E K Mahlamäki,
V Perhoniemi,
A Rajamäki,
J Rautonen,
M Salmenperä,
H Salo,
I Salonen,
E-R Savolainen,
S Sjövall,
M Suistomaa,
M Syrjälä,
A Tienhaara,
M Vähämurto,
T Mäki
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ABSTRACT: We wanted to establish a permanent national database system, which can be utilized to study transfusion recipients and blood use in Finland.
A regularly updated register for permanent use was developed. To study the usability of the database, years 2002 and 2003 were further analysed. Database included all transfused patients in major blood-transfusing hospitals from four university and five central hospital districts managing altogether 63% of Finnish inpatient hospital episodes.
Audit of gathered data reveal 96.8% match in adult blood components with Finnish Red Cross, Blood Service sales figures. Model data set includes 59,535 transfused patients (44.3% men and 55.7% women) having received 529,104 blood components. Half of all blood units were transfused in connection with surgical operations. Most of the blood recipients were elderly (51.6% are over 64 years of age). Blood-component use and transfusion-related costs varied widely between hospitals.
Hospital data managing systems can be useful for creating a population-based database system to monitor and compare transfusion practices. This record provides information about transfusion epidemiology for transfusion professionals, hospital management, and hospital administration.
Vox Sanguinis 09/2006; 91(2):140-7. · 2.86 Impact Factor
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ABSTRACT: A countrywide prospective study on open-heart surgery patients was performed between 1987 and 1989 to determine the prevalence and nature of post-transfusion hepatitis in Finland. Altogether 685 coronary by-pass operation patients, who received on average 12.3 units of blood products, were postoperatively followed for 6 months. Ten blood samples were drawn from each patient. Hepatitis was diagnosed when the alanine aminotransferase values exceeded the upper normal value 2.5 times in one sample and twice in another, and non-viral causes could reasonably be excluded. Eleven hepatitis cases (1.6%) were recorded with a mean incubation period of 8.4 weeks; all represented the non-A, non-B type. The majority had mild symptoms or were asymptomatic but two became icteric. Six patients (55%) had abnormal alanine aminotransferase values for at least 6 months, which indicates possible chronicity. These 685 open-heart surgery patients received a total of 8,436 units of blood products; thus the rate of NANBH cases per 1000 units was as low as 1.3. This is less than recently reported in six other prospective studies.
Transfusion Medicine 07/1991; 1(2):103-7. · 1.14 Impact Factor
