Publications (1)13.45 Total impact
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Article: Insights into Lasalocid A Ring Formation by Chemical Chain Termination In Vivo
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ABSTRACT: Caught in the act: Intermediates in the biosynthesis of lasalocid A are captured in vivo by malonyl carba(dethia)-N-acetyl cysteamine probes. These species constitute novel snapshots of the timing of ether and aromatic ring formation, thus providing valuable insights for the reconstruction and the engineering of polyether biosynthetic pathways.Angewandte Chemie International Edition 01/2011; · 13.45 Impact Factor
