N I Alstrup

Publications (3)6.26 Total impact

• Article: Effect of rectal dilation in fecal incontinence with low rectal compliance. Report of a case.

  N I Alstrup, O O Rasmussen, J Christiansen
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  ABSTRACT: This study was undertaken to determine the effect of rectal dilation in a patient with urge-type fecal incontinence and frequent bowel movements associated with low rectal compliance and capacity. Daily rectal balloon dilation was performed for a period of four weeks. The patient regained complete fecal continence with one to two daily bowel movements. Rectal compliance, capacity, and cross-sectional area increased by 37 to 136 percent. Nine months later the patient was still without symptoms. Rectal balloon dilation may be a therapeutic alternative in selected patients.
  Diseases of the Colon & Rectum 10/1995; 38(9):988-9. · 3.13 Impact Factor
• Article: Rectal compliance determined by rectal endosonography. A new application of endosonography.

  N I Alstrup, B Skjoldbye, O O Rasmussen, N E Christensen, J Christiansen
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  ABSTRACT: The aim of this study was to develop a method for determination of rectal compliance that allows direct measurement of corresponding changes in the rectal cross-sectional area or perimeter and rectal pressure. We developed an anal probe for transrectal endosonography. The probe was tested in vitro, and rectal compliance of six healthy patients was determined. In vitro measurements proved the method to be well reproducible. The method allowed calculation of an endosonographic rectal compliance, which correlated well with rectal compliance measured by the standard method. Endosonographic determination of rectal compliance is possible, and the endosonographic method may give a more precise and reproducible estimation of rectal compliance.
  Diseases of the Colon & Rectum 02/1995; 38(1):32-6. · 3.13 Impact Factor
• Article: [Somatostatinoma in the pancreas].

  N I Alstrup, T K Pless, J Sandermann
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  ABSTRACT: A case of a pancreatic somatostatinoma in a 54 year old male is presented. A pancreatic carcinoma with hepatic metastases were primary diagnosed, and the patient had a palliative choledochoduodenostomy and gastroenteroanastomosis. As he was still alive four years later, the histological samples were reevaluated. Immunohistochemically the tumor was found positive for somatostatin, neuron-specific enolase and pancreatic polypeptide. Symptoms, diagnosis, pathology and treatment in relation to somatostatinomas are discussed.
  Ugeskrift for laeger 07/1994; 156(24):3640-1.