Min Soo Kim

Yonsei University Hospital, Sŏul, Seoul, South Korea

Are you Min Soo Kim?

Claim your profile

Publications (215)338 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: In this study, we isolated a bacteriophage T7-resistant mutant strain of Escherichia coli (named S3) and then proceeded to characterize it. The mutant bacterial colonies appeared to be mucoid. Microarray analysis revealed that genes related to colanic acid production were upregulated in the mutant. Increase in colanic acid production was shown in the mutant bacteria when L-fucose was biochemically measured, and protective capsule formation was observed under an electron microscope. We found a point mutation in the lon gene promoter in S3, the mutant bacteria. Overproduction of colanic acid was observed in some phage-resistant mutant bacteria after infection with other bacteriophages, T4 and lambda. Colanic acid overproduction was also observed in clinically isolated strains of E. coli upon phage infection. The overproduction of colanic acid resulted in the inhibition of bacteriophage adsorption to the host. Biofilm formation initially decreased shortly after infection, but eventually increased after 48 hours of incubation by the emergence of the mutant bacteria. The bacteriophage PBECO4 was shown to infect the colanic acid-overproducing mutant strains of E. coli. We confirmed that gene product of ORF 547 of PBECO4 harbored colanic acid degrading enzymatic (CAE) activity. The mixed infection of T7 and PBECO4 or its purified enzyme (CAE) to the T7-resistant bacteria led to the successful infection of T7. Biofilm formation decreased with the mixed infection, too. This represents a novel strategy for overcoming phage-resistant mutant bacteria where phage cocktails different from those exploiting solely receptor differences are used. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
    Applied and Environmental Microbiology 11/2014; · 3.95 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: 1unprecedented properties, have gained great attraction for the repair of tissues, particularly for those requiring electrical stimuli. While most reports have demonstrated in vitro neural cell responses of the CNTs, little has performed on the in vivo efficacy of CNT-interfaced biomaterials in the repair and regeneration of neural tissues. Thus, here we report for the first time the in vivo functions of CNT-interfaced nerve conduits in the regeneration of rat transected sciatic nerve. Aminated CNTs were chemically tethered onto a surface of aligned phosphate glass microfibers (PGFs) and the CNT-interfaced PGFs (CNT-PGFs) were embedded into three-dimensional poly(-L/D-lactic acid) (PLDLA) tube successfully. In vitro study confirmed that neurites of dorsal root ganglion outgrew actively along the aligned CNT-PGFs and that CNT interfacing significantly increased the maximal neurite length. Sixteen weeks after implantation of a CNT-PGFs nerve conduit into a 10 mm-gap transected sciatic nerve in rats, the number of regenerating axons crossing the scaffold, the cross-sectional area of the re-innervated muscles and the electrophysiological findings were all significantly improved by the interfacing with CNTs. This first in vivo effect of CNT-interfaced scaffold in the regeneration process of a rat transected sciatic nerve strongly supports the potential use of CNT-interfaced PGFs at the interface of nerve conduit and peripheral neural tissues.
    Acta Biomaterialia. 11/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background There is a need for an adjuvant agent of caudal block that prolongs its duration and improves the analgesic efficacy to fasten functional recovery. Magnesium is an N-methyl-D-aspartate receptor antagonist that functions as an analgesic. This study was aimed to evaluate whether magnesium as an adjuvant for caudal block in children can improve postoperative analgesia and functional recovery.Methods Eighty children, 2–6 years of age, undergoing inguinal herniorrhaphy, were included in this prospective, randomized, double-blinded study. For caudal block, Group R received ropivacaine 1.5 mg·ml−1, 1 ml·kg−1 and Group RM received the same dose of ropivacaine mixed with 50 mg of magnesium. The Parents' Postoperative Pain Measure (PPPM) score, analgesic consumption, functional recovery, and adverse effects were evaluated at 6, 24, 48, and 72 h after surgery, as well as daily thereafter until the child showed full functional recovery.ResultsThe PPPM score after hospital discharge was significantly lower for Group RM than for Group R at all times (P < 0.05). Children in Group RM required less fentanyl for rescue analgesia in the recovery area (16.2% vs 39.5%, P = 0.034) and less oral analgesics after discharge (20.5% vs 52.6%, P = 0.007). The time to return of normal functional activity was shorter in Group RM (P < 0.05). The incidence of adverse effects did not differ between groups.Conclusions As an adjuvant for caudal analgesia, 50 mg magnesium provided superior quality of analgesia and faster return of normal functional activity than local anesthetic alone in children.
    Pediatric Anesthesia 10/2014; · 2.44 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: The effects of the anisotropic bending stiffness of gas diffusion layers (GDLs) on the performance of polymer electrolyte membrane fuel cells with metallic bipolar plates (MBPs), having different channel depths, are investigated. The current–voltage performance of fuel cells with 90° GDLs, whose directions of higher stiffness are perpendicular to the direction of the major flow field, is generally higher than that of cells with 0° GDLs, whose directions of higher stiffness are parallel to the direction of the major flow field. In the shallowest channel, the air pressure drop (ΔP) values of the 90° GDL cells are clearly lower than those of the 0° GDL cells, indicating less intrusion of the 90° GDL into the MBP channels. However, no significant difference appears between the air ΔP values of 0° and 90° GDL cells employing deeper channels. In comparison with other cells employing deeper channels, a dramatic increase in the high-frequency resistance of both the 0° and 90° GDL cells with the shallowest channel is unexpectedly observed, presumably due to the exceptional increase in the hydrogen and air pressure, which may cause more deformation and poor contact status of the GDLs in the cell. The cross-sectional images of GDLs upon compression indicate that the difference of blocked channel area between 0° and 90° GDL cells is much larger in the case of the shallowest channel, resulting in the observed air ΔP, whereas it is substantially negligible for the deepest channel.
    Renewable Energy 09/2014; 69:356–364. · 3.36 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Background An intracuff pressure of 80 cm H2O in the adult-sized laryngeal mask airway Supreme has been recommended to obtain a higher oropharyngeal leak pressure (OLP). However, the intracuff pressure for the higher OLP in the pediatric laryngeal mask airway Supreme could be different from that in the adult-sized laryngeal mask airway Supreme. Thus, we measured and compared OLP at three intracuff pressures of 40, 60, and 80 cm H2O in the pediatric laryngeal mask airway Supreme.Methods This study was designed as a randomized crossover study and enrolled 36 children, aged 0–108 months and 5–30 kg in weight. After insertion of the laryngeal mask airway Supreme, oropharyngeal leak pressure (OLP) was measured at intracuff pressures of 40, 60, and 80 cm H2O according to one of six sequences produced on the basis of 3 × 6 Williams crossover design. During the intraoperative period, the laryngeal mask airway Supreme was maintained using the last intracuff pressure of the allocated sequence. The intraoperative and postoperative complications were compared among three maintenance intracuff pressures.ResultsOLP at the intracuff pressure of 60 cm H2O was significantly higher than that of 40 cm H2O (17.9 ± 3.9 vs 16.9 ± 4.2 cm H2O, P = 0.004) and was comparable with that of 80 cm H2O (17.9 ± 3.9 vs 17.8 ± 4.6 cm H2O, P = 0.938). There were no significant differences of intraoperative and postoperative complications among the three maintenance intracuff pressures.Conclusion Our results suggest that the use of an intracuff pressure of 60 cm H2O in pediatric laryngeal mask airway Supreme provides a higher OLP compared with 40 cm H2O.
    Pediatric Anesthesia 07/2014; · 2.44 Impact Factor
  • Dong Ho Kim, Min Soo Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: The mass flow rate of secondary fluid in a water heater heat pump determines not only the discharge water temperature but also the heat pump performances. As water flow rate decreases, water discharge temperature increases; however, the COP (coefficient of performance) deteriorates due to the increase of high side pressure. In this study, cascade cycle which is used for a water heater heat pump was studied to verify the effect of the water temperature lift in terms of pressure and performance change. Also, the optimal intermediate temperature of cascade cycle with respect to temperature lift was studied and this temperature was adopted for a heat pump transient operation. The heat pump was operated to meet the constant heating capacity and target intermediate temperature by PID control of compressor speed. The transient results showed that water temperature lift determines not only the vertical temperature profile of water reservoir but also the transient performance.
    Applied Thermal Engineering 06/2014; 67(s 1–2):273–282. · 2.13 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Emerging evidence shows that the eradication rate of proton pump inhibitor (PPI)-based triple therapy for the first-line treatment of Helicobacter pylori (H. pylori) has decreased. To clarify the trend of eradication rate of PPI-based triple therapy and to assess the related factors in Korea during the past decade. We prospectively prescribed the triple regimen for seven days (PPI + amoxicillin 1.0 g + clarithromycin 500 mg, twice a day) from March 2003 to May 2013 in 2,202 H. pylori-positive patients. Antibiotic susceptibility tests were performed by the agar dilution method, and the CYP2C19 genotype was determined by the PCR method. In the past decade, the annual eradication rate showed a decreasing trend in intention-to-treat and per-protocol analyses (P = 0.001, both). The antibiotic resistance was increased to amoxicillin (7.2-17.2 %, P = 0.003) and clarithromycin (23.2-37.3 %, P = 0.010) during the study period. The poor metabolizer genotype of CYP2C19 showed a high eradication rate compared to the extensive metabolizer (86.8 vs. 78.2 %, P = 0.035). In addition, age ≥ 50 years, female gender, BMI < 25 kg/m(2), amoxicillin and/or clarithromycin resistance were associated with treatment failure on univariate analysis. However, on multivariate analysis, clarithromycin resistance was the only significant factor for treatment failure (OR, 12.76; 95 % CI, 5.58-29.18; P < 0.001). An increase in clarithromycin resistance has led to decreased eradication rate of first-line triple therapy, and; hence, a new strategy is needed to improve the eradication rate of H. pylori.
    Digestive Diseases and Sciences 03/2014; · 2.26 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: In Alzheimer's disease (AD), extensive neuronal loss and a deficiency of the neurotransmitter acetylcholine (ACh) are the major characteristics during pathogenesis in the brain. In the present study, we aimed to investigate whether representative ginsenosides from ginseng can regulate choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT), which are required for cholinergic neurotransmission. Our results revealed that Re and Rd induced effectively the expression of ChAT/VAChT genes in Neuro-2a cells as well as ACh elevation. Microtubule-associated protein-2 (MAP-2), nerve growth factor receptor (p75), p21, and TrkA genes and proteins were also significantly expressed. Moreover, both activated extracelullar signal-regulated protein kinase (ERK) and Akt were inhibited by K252a, a selective Trk receptor inhibitor. These findings strongly indicate that Re and Rd play an important role in neuronal differentiation and the NGF-TrkA signaling pathway. High performance liquid chromatography analysis showed that Re and Rd administered orally were transported successfully into brain tissue and increased the level of ChAT and VAChT mRNA. The present study demonstrates that Re and Rd are selective candidates for upregulation of the expression of cholinergic markers, which may counter the symptoms and progress of AD.
    Biological & Pharmaceutical Bulletin 03/2014; · 1.85 Impact Factor
  • Chul Woo Roh, Min Soo Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: In this study, we applied a vapor-injection (VI) technique in a cascade heat pump system. The VI was applied to both upper and lower stage cycles. Test results showed that heating and cooling capacities increased by using the VI technique (12% and 6%, respectively); however, the system COP decreased (6.6% at the injection ratio of 16.7%). The cascade system which has a small compression ratio and a cascade condenser, cannot fully utilize the VI's advantages to improve the system COP. However, the VI is effective for the system reliability and capacity improvement. We also found that the VI in the upper and lower stage cycles had different effect on overall cycle operating characteristic.
    International Journal of Refrigeration 02/2014; 38:168–177. · 1.79 Impact Factor
  • Jae Seung Lee, Mo Se Kim, Min Soo Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: Environmental issues such as stratospheric ozone depletion and global warming have been the primary motivations for recent research in the air-conditioning and refrigeration fields. The CO2 air-conditioning system forms a transcritical cycle which shows slightly degraded performance compared to the conventional system. To overcome this disadvantage, a cycle adopting an ejector is suggested. Experimental results of a CO2 air-conditioning system using an ejector were compared for various outdoor temperatures and inverter frequencies. The COPs of an air-conditioning system using an ejector and conventional system were calculated and compared based on the pressures and temperatures of experiments. The cooling capacity and COP in the air-conditioning system using an ejector are higher than those in the conventional system at an entrainment ratio greater than 0.76. In addition, better performance is shown at entrainment ratio greater than a certain value in other test conditions.
    International Journal of Refrigeration 02/2014; 38:140–152. · 1.79 Impact Factor
  • Source
    Min Soo Kim, Sunghoon Kim, Heejoon Myung
    [Show abstract] [Hide abstract]
    ABSTRACT: Hepatitis C virus (HCV) causes chronic hepatitis leading to liver fibrosis and autoimmune diseases. AIMP1/p43 is a multifunctional protein initially known as a cofactor of aminoacyl tRNA synthetase complex. Its function includes negative regulation of TGF-β signaling and suppression of Lupus-like autoimmune disease by inhibition of surface expression of gp96. HCV E2 was shown to directly interact with AIMP1/p43 by GST pulldown assay and coimmunoprecipitation. Their subcellular colocalization was observed in an immunofluorescence confocal microscopy. We showed that HCV E2 led to degradation of AIMP1/p43 in two ways. First, in the presence of HCV E2, endogenous AIMP1/p43 was shown to be degraded in an ubiquitin-dependent proteasome pathway. Second, grp78, an ER chaperone, was shown to interact with and stabilize AIMP1/p43. And HCV E2 inhibited this interaction leading to reduction of cellular AIMP1/p43. The degradation of AIMP1/p43 by HCV E2 resulted in increase of TGF-β signaling and cell surface expression of gp96. Thus we suggest that these are novel mechanisms responsible for liver fibrosis and autoimmune diseases caused by HCV.
    PLoS ONE 01/2014; 9(5):e96302. · 3.53 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: We prepared reactive mesoporous silica particles by co-condensation of an amphiphilic organosilica precursor with tetraethoxysilane, where the hydrophobic part of the amphiphile was tethered to the pore wall through a thermally reversible urethane bond. By utilizing this urethane group, various functional moieties such as carboxyl, sulfo, amino, and methyl carbamate groups were selectively introduced inside the pore and their interactions with CO2 were investigated. The carboxyl and amino group-functionalized silica particles exhibited higher CO2 adsorption capacity than the methyl carbamate group-functionalized silica particle. In particular, the high value for the initial isosteric heat of adsorption was observed for the carboxyl group-functionalized silica particle, suggesting the strong interaction of the carboxyl group with CO2.
    Science of Advanced Materials 01/2014; 6(7). · 2.51 Impact Factor
  • Source
    Min Soo Kim, Yoon Nyun Kim, Yun Seok Heo
    [Show abstract] [Hide abstract]
    ABSTRACT: Distinct features in heart rate signals during the driver's wake and sleep states could provide an initiative for the development of a safe driving systems such as drowsiness detecting sensor in a smart wheel. We measured ECG from health subjects ( in age) during the wake and drowsiness states. The proposed method is able to detect R waves and R-R interval calculation in the ECG even when the signal includes in abnormal signals. Heart rate variability(HRV) was investigated for the time domain and frequency domains. The STD HR(0.029), NN50(0.044) and VLF power(0.0018) of the RR interval series of the subjects were significantly different from those of the control group (p < 0.05). In conclusion, there are changes in heart rate from wake to drowsiness that are potentially to be detected. The results in our study could be useful for the development of drowsiness detection sensors for effective real-time monitoring.
    Transactions of the Korean Society of Automotive Engineers. 01/2014; 22(3).
  • Mo Se Kim, Chang Soo Shin, Min Soo Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: Carbon dioxide (CO2) is one of the replacements of the synthetic refrigerants whose properties are good as a refrigerant with no ozone depletion and a very little global warming effect. However, its low critical temperature makes a CO2 refrigeration system to form trans-critical cycle and determination of an optimal heat rejection pressure becomes an important problem for the best performance. Until now, number of studies have been published which correlate preliminarily obtained data map with some major operating parameters. In this study, a generally usable real time optimal control method is introduced. This real time optimal control method does not require preliminarily obtained correlations and makes the system operate in a nearly optimal region. Additionally, its limitations which produce undesirable errors and bias of controlled value were also treated in this paper. Three causes of errors were discussed and it is helpful to improve the control method.
    International Journal of Refrigeration 01/2014; · 1.79 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Thrombin playing a pivotal role in coagulation cascade may influence the onset and progression of atherosclerosis as a pro-inflammatory mediator. This study investigated whether phloretin found in apple tree leaves, severed a linkage between thrombosis and atherosclerosis by thrombin. Human endothelial cells were pre-treated with 1-20 μM phloretin and stimulated with 10 U/mL thrombin. Phloretin attenuated adhesion of THP-1 monocytes and platelets to thrombin-inflamed endothelial cells with concurrent inhibition of protease-activated receptor (PAR-1) induction. The thrombin induction of endothelial CD40, endothelial integrin β3 and P-selectin, and monocytic CD40L was dampened by phloretin. Additionally, phloretin inhibited monocyte secretion of MCP-1, IL-6 and IL-8 responsible for pro-inflammatory activity of thrombin inducing endothelial CD40. The monocyte COX-2 induction and PGE2 secretion due to thrombin were down-regulated by phloretin, deterring endothelial CD40 expression. Thrombin promoted production of PAI-1 and tissue factor in monocytes was attenuated by phloretin through blocking PAR-1 and CD40. Thrombin up-regulated the induction of endothelial connective tissue growth factor independent of PAR-1 activation, which was reversed by phloretin. Phloretin disturbed tethering and stable adhesion of monocytes and platelets onto endothelium during increased thrombosis by thrombin. Phloretin would be a potent agent preventing thrombosis and atherosclerosis.
    Molecular Nutrition & Food Research 12/2013; · 4.31 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: There are few reports in the literature of complete obstruction of the vertebral artery (VA) due to an electric screw driver bit penetration through the neural foramen into the spinal canal with Brown-Séquard syndrome (BSS). A 25-year-old man was admitted to the emergency department with a penetrated neck injury by an electric screw driver bit after a struggle. The patient presented the clinical features of BSS. Computed tomography scan revealed that the electric screw driver bit penetrated through the right neural foramen at the level of C3-4, and it caused an injury to the right half of the spinal cord. Emergent angiography revealed VA dissection, which was managed by immediate coil embolization at both proximal and distal ends of the injury site. After occlusion of the VA, the electric screw driver bit was extracted under general anesthesia. Bleeding was minimal and controlled without difficulties. No postoperative complications, such as wound dehiscence, CSF leakage, or infection, were noted. Endovascular approaches for occlusion of vertebral artery lesions are safe and effective methods of treatment.
    Korean Journal of Spine. 12/2013; 10(4):258-60.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Although the kinase receptor TrkA may play an important role in acute myeloid leukemia (AML), its involvement in other types of leukemia has not been reported. Furthermore, how it contributes to leukemogenesis is unknown. Here, we describe a molecular network that is important for TrkA function in leukemogenesis. We found that TrkA is frequently overexpressed in other types of leukemia such as acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), and myelodysplastic syndrome (MDS) including AML. In addition, TrkA was overexpressed in patients with MDS or secondary AML evolving from MDS. TrkA induced significant hematological malignancies by inducing PLK-1 and Twist-1, and enhanced survival and proliferation of leukemia, which was correlated with activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway. Moreover, endogenous TrkA associated with c-Src complexes was detected in leukemia. Suppression of c-Src activation by TrkA resulted in markedly decreased expression of PLK-1 and Twist-1 via suppressed activation of Akt/mTOR cascades. These data suggest that TrkA plays a key role in leukemogenesis and reveal an unexpected physiological role for TrkA in the pathogenesis of leukemia. These data have important implications for understanding various hematological malignancies.
    Biochemical and Biophysical Research Communications 11/2013; 441(2):431-7. · 2.28 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The increasing trend of antibiotic resistance requires effective second-line Helicobacter pylori (H. pylori) treatment in high prevalence area of H. pylori. The aim of our study was to evaluate the reinfection rate of H. pylori after second-line treatment that would determine the long-term follow up effect of the rescue therapy. A total of 648 patients who had failed previous H. pylori eradication on standard triple therapy were randomized into two regimens: 1, esomeprazole (20 mg b.i.d), tripotassium dicitrate bismuthate (300 mg q.i.d), metronidazole (500 mg t.i.d), and tetracycline (500 mg q.i.d) (EBMT) or 2, moxifloxacin (400 mg q.d.), esomeprazole (20 mg b.i.d), and amoxicillin (1000 mg b.i.d.) (MEA). At four weeks after completion of eradication therapy, H. pylori tests were performed with 13C urea breath test or invasive tests. In patients who maintained continuous H. pylori negativity for the first year after eradication therapy, H. pylori status was assessed every year. For the evaluation of risk factors of reinfection, gender, age, clinical diagnosis, histological atrophic gastritis or intestinal metaplasia were analyzed. The recrudescence rate of the EBMT was 1.7 % and of the MEA group 3.3 % (p = 0.67). The annual reinfection rate of H. pylori of EBMT was found to be 4.45 % and the MEA group 6.46 %. Univariate analysis (Log-rank test) showed no association with any clinical risk factor for reinfection. The long-term reinfection rate of H. pylori stayed low in both of bismuth-containing quadruple therapy and moxifloxacin-based triple therapy; thus reinfection cannot affect the choice of second-line treatment.Trial registration: Clinical Trial Registration Number NCT01792700.
    BMC Gastroenterology 09/2013; 13(1):138. · 2.11 Impact Factor
  • Sun Young Kim, Yuhyung Shin, Min Soo Kim
    [Show abstract] [Hide abstract]
    ABSTRACT: The purpose of the current study is to examine the cross-level three-way interactions among individual trait positive affect (PA), group trait PA, and group PA diversity on individual work outcomes. Drawing on situation strength theory, we hypothesized that the relationship of individual trait PA with work outcomes depends on the strength of a group's affective contexts including group trait PA and PA diversity. The hierarchical linear modelling results for 261 employees in 42 South Korean organizational teams showed that individuals' trait PA was positively associated with their team commitment, job satisfaction, and organizational citizenship behaviour (OCB). The findings also demonstrated that individual trait PA had the strongest relationship with team commitment when group trait PA was low and PA diversity was high simultaneously. In addition, the relationship between individual trait PA and OCB was found to be stronger for affectively diverse groups than for homogeneous groups.
    Asian Journal Of Social Psychology 09/2013; 16(3). · 0.83 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Many diffusion tensor imaging (DTI) studies have reported an association between cingulum injury and cognition in patients with traumatic brain injury (TBI) using DTI parameters. In this study, we attempted to investigate the relation between cingulum injury and cognition in chronic patients with TBI, using the integrity of the cingulum as well as DTI parameters. Thirty five consecutive chronic patients with TBI were recruited. The intelligence quotient (IQ) of the Wechsler Intelligence Scale and Memory Assessment Scale (MAS) was used for assessment of cognition. The patients were classified into three groups, according to continuity to the lower portion of the genu of the corpus callosum: type A-both sides of the cingulum showed intact continuity, type B-either cingulum showed a discontinuation, and, type C-both cingulums showed discontinuation. We measured the fractional anisotropy (FA), apparent diffusion coefficient (ADC), and voxel number of both cingulums. The IQ and MAS scores of type A and B were significantly higher than those of type C, respectively (p < 0.05), however, we did not observe a significant difference between type A and type B (p > 0.05). A positive correlation was observed between the FA value of the cingulum, and IQ and MAS, respectively (IQ r = 0.373, p < 0.05, MAS r = 0.357, p < 0.05), and between the voxel number and MAS (r = 0.500, p < 0.05). By contrast, we observed a negative correlation between the ADC value and IQ (r = -0.353, p < 0.05). In terms of integrity to the basal forebrain and DTI parameters of the injured cingulum, DTI findings showed a close association with whole cognition and memory in chronic patients with TBI.
    Neurorehabilitation 08/2013; · 1.42 Impact Factor

Publication Stats

959 Citations
338.00 Total Impact Points

Institutions

  • 2014
    • Yonsei University Hospital
      Sŏul, Seoul, South Korea
  • 1994–2014
    • Seoul National University
      • • School of Mechanical and Aerospace Engineering
      • • Department of Materials Science and Engineering
      Sŏul, Seoul, South Korea
  • 2012–2013
    • Seoul National University Bundang Hospital
      Sŏul, Seoul, South Korea
  • 2010–2013
    • CHA University
      • Department of Neurosurgery
      Sŏul, Seoul, South Korea
    • Hanyang University
      • School of Business
      Ansan, Gyeonggi, South Korea
    • Yonsei University
      • Department of Mechanical Engineering
      Sŏul, Seoul, South Korea
  • 2008–2013
    • Hankuk University of Foreign Studies
      • Department of Bioscience and Biotechnology
      Seoul, Seoul, South Korea
    • National Cancer Center Korea
      Kōyō, Gyeonggi Province, South Korea
    • University of Seoul
      Sŏul, Seoul, South Korea
    • Sogang University
      • Department of Chemistry
      Seoul, Seoul, South Korea
    • Ajou University
      Sŏul, Seoul, South Korea
  • 2007–2013
    • Hallym University
      • Department of Food Science and Nutrition
      Seoul, Seoul, South Korea
  • 2010–2012
    • Inje University Paik Hospital
      Sŏul, Seoul, South Korea
    • Keimyung University
      Sŏul, Seoul, South Korea
  • 2009–2012
    • Korea Electrotechnology Research Institute-KERI
      Tsau-liang-hai, Busan, South Korea
    • Dongguk University
      Sŏul, Seoul, South Korea
  • 2002–2012
    • Korea Advanced Institute of Science and Technology
      • • Department of Computer Science
      • • Department of Biological Sciences
      Sŏul, Seoul, South Korea
  • 2011
    • Chonnam National University
      Gwangju, Gwangju, South Korea
  • 2009–2010
    • Korea University
      • Department of Chemical and Biological Engineering
      Sŏul, Seoul, South Korea
  • 2008–2010
    • Toyohashi University of Technology
      • Department of Electrical and Electronic Information Engineering
      Toyohasi, Aichi, Japan
  • 2003–2010
    • Yeungnam University
      • Department of Electronic Engineering
      Asan, South Chungcheong, South Korea
  • 2007–2009
    • Seoul Medical Center
      Sŏul, Seoul, South Korea
  • 2003–2009
    • Korea Research Institute of Bioscience and Biotechnology KRIBB
      • Chemical Biology Research Center
      Ansan, Gyeonggi, South Korea
  • 2006
    • Korea Institute of Machinery and Materials
      Sŏul, Seoul, South Korea
  • 2002–2006
    • Samsung Advanced Institute of Technology
      Usan-ri, Gyeonggi Province, South Korea
  • 2004
    • Pusan National University
      • Department of Polymer Science and Engineering
      Pusan, Busan, South Korea