Publications (2)3.56 Total impact
Article: The Y-chromosome landscape of the Philippines: extensive heterogeneity and varying genetic affinities of Negrito and non-Negrito groups.[show abstract] [hide abstract]
ABSTRACT: The Philippines exhibits a rich diversity of people, languages, and culture, including so-called 'Negrito' groups that have for long fascinated anthropologists, yet little is known about their genetic diversity. We report here, a survey of Y-chromosome variation in 390 individuals from 16 Filipino ethnolinguistic groups, including six Negrito groups, from across the archipelago. We find extreme diversity in the Y-chromosome lineages of Filipino groups with heterogeneity seen in both Negrito and non-Negrito groups, which does not support a simple dichotomy of Filipino groups as Negrito vs non-Negrito. Filipino non-recombining region of the human Y chromosome lineages reflect a chronology that extends from after the initial colonization of the Asia-Pacific region, to the time frame of the Austronesian expansion. Filipino groups appear to have diverse genetic affinities with different populations in the Asia-Pacific region. In particular, some Negrito groups are associated with indigenous Australians, with a potential time for the association ranging from the initial colonization of the region to more recent (after colonization) times. Overall, our results indicate extensive heterogeneity contributing to a complex genetic history for Filipino groups, with varying roles for migrations from outside the Philippines, genetic drift, and admixture among neighboring groups.European journal of human genetics: EJHG 09/2010; 19(2):224-30. · 3.56 Impact Factor
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ABSTRACT: Human expansion into the far reaches of the Pacific has occurred within the past 3000–4000 years. This is so recent that it is arguably the best opportunity to test models of the origin and dispersal of human groups and their domesticated plants and animals, cultural and linguistic evolution, human impacts on a pristine environment, and the lower limits for a long-term sustainable population. Multidisciplinary research is essential because these models must account for archaeological, ecological, cultural, historical, social, linguistic and (both mitochondrial and nuclear) genetic data. This synthesis has not yet been achieved for any settlement in the world, but there has been considerable progress recently on integrating these disciplines with respect to the settlement of Polynesia.Trends in Ecology & Evolution.