ABSTRACT: Abstract The effects of crude extracts and an isolated compound from the leaves of milkweed, Pergularia
daemia (Forssk) Choiv., on the antifeedant activity against two important lepidopteran pests, Helicoverpa
armigera (Hub.) and Spodoptera litura (F.), were studied. Maximum antifeedant activity was recorded in
ethyl acetate crude extract against H. armigera (70.3%) and S. litura (71.82%) at 1% concentration. Ethyl
acetate crude extract was further subjected to column chromatography, which was performed using hexane as initial solvent and then by increasing the polar strength using ethyl acetate. Fractions collected at hexane and ethyl acetate (80:20) yielded 6-(4,7-hydroxy-heptyl) quinone, a novel compound which showed significant antifeedant activity against H. armigera (80.22% at 2000 ppm) and S. litura (68.31% at 2000 ppm).
Phytoparasitica (2011) 39:145–150. 01/2011;