M Tanaka

National Institute for Fusion Science, Tokitsu-chō, Gifu, Japan

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Publications (613)1325.17 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: Free water tritium (FWT) and organically bound tritium (OBT) concentrations in pine needles have been investigated to understand the regional background tritium concentration in Toki City. Samples were regularly collected from pine trees on the National Institute for Fusion Science campus (1998-2012) and the nearby Shiomi Park (SP; 2002-12). FWT and OBT concentrations of the former samples ranged from 0.33 to 0.92 and 0.41 to 1.10 Bq l(-1), respectively, while those of the latter samples ranged from 0.32 to 0.86 and 0.33 to 0.79 Bq l(-1), respectively. Results of both sampling sites were almost the same, and they have been gradually decreased year by year. Concentration level of tritium for Toki City was close to the average background level in Japan. The OBT/FWT ratios were almost 1.0. The apparent half-life of FWT in this period was estimated as almost 10 y, and that of OBT was estimated as almost 12 y; these values were almost the same as the physical half-life. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
    Radiation Protection Dosimetry 05/2015; DOI:10.1093/rpd/ncv246 · 0.86 Impact Factor
  • M Tanaka, T Uda
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    ABSTRACT: Atmospheric tritium concentrations of HTO, HT and CH3T have been measured at Toki, Japan, for the environmental impact assessment of tritium for a fusion test facility. According to the data from 2004 to 2012, the concentrations of HT and HTO in water vapour tend to increase in spring. The seasonal variation in HT concentration at Toki was compared with the H2 concentration between 1990 and 2005 at Tae-ahn Peninsula, Republic of Korea, which is at approximately the same latitude as Toki. The monthly average of HT-specific activity varied from 1.24 × 10(5) to 1.76 × 10(5) TU. The peak of the monthly average H2 concentration did not match that of HT. This indicates that the mechanism of the production or the source of HT might be different from the production mechanism of H2. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
    Radiation Protection Dosimetry 05/2015; DOI:10.1093/rpd/ncv241 · 0.86 Impact Factor
  • R. Nakane, S. Sugahara, M. Tanaka
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    ABSTRACT: We systematically investigate the structural and magnetic properties of ferromagnetic Fe1− x Si x (0.18 ≤ x ≤ 0.33) films formed by rapid thermal annealing (RTA) on silicon-on-insulator (SOI) substrates. During RTA of an Fe film deposited on a SOI substrate (consisting of a top Si layer, a buried oxide SiO2 layer, and a Si substrate), an Fe1− x Si x film is synthesized by the thermal reaction of the deposited Fe film and the top Si layer, but the reaction is limited by the buried oxide layer in the SOI substrate, thus the Si concentration x in Fe1− x Si x can be controlled by both the initial thicknesses of the Fe film and the top Si layer. A variety of characteristics show that single-phase Fe1− x Si x (x = 0.18, 0.22, and 0.25) films with D03 + B2 structure are successfully obtained by choosing the optimum annealing temperature and time. Furthermore, the ordering fraction of D03 and B2 structures in these films is found to be more than 87%, indicating that the crystalline quality of these films is comparable to that of bulk Fe1− x Si x materials reported so far. On the other hand, it is found that the Fe1− x Si x (x = 0.33) film has Fe3Si and FeSi phases as in the case of bulk Fe1− x Si x with x = 0.33. The film production technique and the quality of the ferromagnetic Fe1− x Si x presented in this study are very attractive and useful for silicon-based spintronic devices which are compatible with the complementary metal-oxide-semiconductor technology.
    Journal of Applied Physics 04/2015; 117(13):133906. DOI:10.1063/1.4915335 · 2.19 Impact Factor
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    ABSTRACT: Simultaneous pancreas-kidney transplantation (SPK) is a definitive treatment for type 1 diabetics with end-stage renal disease (ESRD). Because of the shortage of deceased donors in Japan, the mortality rate during the waiting period is high. We evaluated mortality risk in patients with type 1 diabetes waiting for SPK, and the benefit of living-donor kidney transplantation (LDK) preceding pancreas transplantation, which may reduce mortality in patients awaiting SPK. This retrospective study included 71 patients with type 1 diabetes. Twenty-six patients underwent SPK, 15 underwent LDK, and 30 were waiting for SPK. Their cumulative patient and graft survival rates were retrospectively evaluated. Risk factors contributing to mortality in patients with type 1 diabetes awaiting SPK were evaluated with the use of a Cox proportional hazards model. The 5-year cumulative patient survival rates in the SPK and LDK groups were 100% and 93.3%, respectively (P = .19), and 5-year kidney graft survival rates were 95.7% and 100% (P = .46), respectively. The cumulative survival rate in patients awaiting SPK was 77.7% at 5 years after registration. Duration of dialysis was the only factor significantly associated with patient and graft survivals according to both univariate and multivariate analyses. Patient and graft survival rates were similar in the SPK and LDK groups, but the survival rate of patients awaiting SPK decreased over time. Duration of dialysis was an independent risk factor for patient and graft survival. LDK preceding pancreas transplantation may be an effective therapeutic option for patients with type 1 diabetes and ESRD. Copyright © 2015 Elsevier Inc. All rights reserved.
    Transplantation Proceedings 04/2015; 47(3):733-7. DOI:10.1016/j.transproceed.2014.12.048 · 0.95 Impact Factor
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    ABSTRACT: Renal transplantation has been established as a treatment for end-stage renal disease (ESRD) due to diabetic nephropathy. However, few studies have focused on the outcome after renal transplantation in patients with ESRD and type 2 diabetic nephropathy. To investigate the effect of renal transplantation on ESRD with type 2 diabetic nephropathy, we retrospectively analyzed patients who received renal transplantation at our facility. This study aimed to compare the outcome of renal transplantation for type 2 diabetic nephropathy with that for nondiabetic nephropathy. We studied 290 adult patients, including 65 with type 2 diabetic nephropathy (DM group) and 225 with nondiabetic nephropathy (NDM group), who underwent living-donor renal transplantation at our facility from February 2008 to March 2013. We compared the 2 groups retrospectively. In the DM and NDM groups, the 5-year patient survival rates were 96.6% and 98.7%, and the 5-year graft survival rates were 96.8% and 98.0%, respectively, with no significant differences between the groups. There were no significant differences in the rates of surgical complications, rejection, and infection. The cumulative incidence of postoperative cardiovascular events was higher in the DM group than in the NDM group (8.5% vs 0.49% at 5 years; P = .002). Patient and graft survival rates after renal transplantation for type 2 diabetic nephropathy are not inferior to those for recipients without diabetic nephropathy. Considering the poor prognosis of patients with diabetic nephropathy on dialysis, renal transplantation can provide significant benefits for these patients. Copyright © 2015 Elsevier Inc. All rights reserved.
    Transplantation Proceedings 03/2015; DOI:10.1016/j.transproceed.2014.12.047 · 0.95 Impact Factor
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    ABSTRACT: We herein present a novel technique for laparoscopic en bloc excision involving anteriorly extended intersphincteric resection with partial resection of the posterior lobe of the prostate for large rectal gastrointestinal stromal tumors (GISTs). The sequence of neoadjuvant imatinib therapy and this less invasive surgery for marginally resectable rectal GISTs has the potential to obviate the need for urinary reconstruction and permanent stomas without jeopardizing the tumor margin status.
    Techniques in Coloproctology 12/2014; DOI:10.1007/s10151-014-1261-6 · 1.34 Impact Factor
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    ABSTRACT: This review presents the recent progress in computational materials design, experimental realization, and control methods of spinodal nanodecomposition under three- and two-dimensional crystal-growth conditions in spintronic materials, such as magnetically doped semiconductors. The computational description of nanodecomposition, performed by combining first-principles calculations with kinetic Monte Carlo simulations, is discussed together with extensive electron microscopy, synchrotron radiation, scanning probe, and ion beam methods that have been employed to visualize binodal and spinodal nanodecomposition (chemical phase separation) as well as nanoprecipitation (crystallographic phase separation) in a range of semiconductor compounds with a concentration of transition metal (TM) impurities beyond the solubility limit. The role of growth conditions, co-doping by shallow impurities, kinetic barriers, and surface reactions in controlling the aggregation of magnetic cations is highlighted. According to theoretical simulations and experimental results the TM-rich regions appear either in the form of nanodots (the {\em dairiseki} phase) or nanocolumns (the {\em konbu} phase) buried in the host semiconductor. Particular attention is paid to Mn-doped group III arsenides and antimonides, TM-doped group III nitrides, Mn- and Fe-doped Ge, and Cr-doped group II chalcogenides, in which ferromagnetic features persisting up to above room temperature correlate with the presence of nanodecomposition and account for the application-relevant magneto-optical and magnetotransport properties of these compounds. Finally, it is pointed out that spinodal nanodecomposition can be viewed as a new class of bottom-up approach to nanofabrication.
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    ABSTRACT: We demonstrate monolithic integration of pseudo-spin-MOSFETs (PS-MOSFETs) using vendor-made MOSFETs fabricated in a low-cost multi-project wafer (MPW) product and lab-made magnetic tunnel junctions (MTJs) formed on the topmost passivation film of the MPW chip. The tunneling magnetoresistance (TMR) ratio of the fabricated MTJs strongly depends on the surface roughness of the passivation film. Nevertheless, after the chip surface was atomically flattened by SiO2 deposition on it and successive chemical–mechanical polish (CMP) process for the surface, the fabricated MTJs on the chip exhibits a sufficiently large TMR ratio (>140%) adaptable to the PS-MOSFET application. The implemented PS-MOSFETs show clear modulation of the output current controlled by the magnetization configuration of the MTJs, and a maximum magnetocurrent ratio of 90% is achieved. These magnetocurrent behaviour is quantitatively consistent with those predicted by HSPICE simulations. The developed integration technique using a MPW CMOS chip would also be applied to monolithic integration of CMOS devices/circuits and other various functional devices/materials, which would open the door for exploring CMOS-based new functional hybrid circuits.
    Solid-State Electronics 07/2014; DOI:10.1016/j.sse.2014.06.004 · 1.51 Impact Factor
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    ABSTRACT: The electronic and magnetic properties of Fe atoms in the ferromagnetic semiconductor (In,Fe)As codoped with Be have been studied by x-ray absorption spectroscopy (XAS) and x-ray magnetic circular dichroism (XMCD) at the Fe $L_{2,3}$ edge. The XAS and XMCD spectra showed simple spectral line shapes similar to Fe metal, but the ratio of the orbital and spin magnetic moments ($M_\mathrm{orb}$/$M_\mathrm{spin}$) estimated using the XMCD sum rules was significantly larger than that of Fe metal, indicating a significant orbital moment of Fe $3d$ electrons in (In,Fe)As:Be. The positive value of $M_\mathrm{orb}$/$M_\mathrm{spin}$ implies that the Fe $3d$ shell is more than half-filled, which arises from the hybridization of the Fe$^{3+}$ ($d^5$) state with the charge-transfer $d^6\underline{L}$ states, where $\underline{L}$ is a ligand hole in the host valence band. The XMCD intensity as a function of magnetic field indicated hysteretic behavior of the superparamagnetic-like component due to discrete ferromagnetic domains.
    Applied Physics Letters 05/2014; 105(3). DOI:10.1063/1.4890733 · 3.52 Impact Factor
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    ABSTRACT: The electronic structure of doped Mn in (Ga,Mn)As is studied by resonant inelastic x-ray scattering. From configuration-interaction cluster-model calculations, the line shapes of the Mn L3 resonant inelastic x-ray scattering spectra can be explained by d-d excitations from the Mn ground state dominated by charge-transferred states, in which hole carriers are bound to the Mn impurities, rather than a pure acceptor Mn2+ ground state. Unlike archetypical d-d excitation, the peak widths are broader than the experimental energy resolution. We attribute the broadening to a finite lifetime of the d-d excitations, which decay rapidly to electron-hole pairs in the host valence and conduction bands through the hybridization of the Mn 3d orbital with the ligand band.
    Physical Review Letters 03/2014; 112(10):107203. DOI:10.1103/PhysRevLett.112.107203 · 7.73 Impact Factor
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    ABSTRACT: Background Once-daily extended-release tacrolimus (Tac-QD) has been shown to have equivalent efficacy and safety to the twice-daily formulation (Tac-BID) in kidney transplant patients. However, detailed comparison of allograft pathology found on a protocol biopsy (PB) in Tac-QD– versus Tac-BID–based regimens has not been described. Methods We retrospectively investigated 119 de novo living donor kidney transplant patients treated with Tac-QD (n = 90) or Tac-BID (n = 29) and their 3- and 12-month PB results. Other immunosuppressive drugs administered included basiliximab, mycophenolate mofetil, and methylprednisolone. We evaluated daily doses and trough levels of Tac and serum creatinine levels, and compared pathologic findings. Results Daily doses were higher in the Tac-QD group, but trough levels and serum creatinine levels were comparable. On 3- and 12-month PB, the frequency of subclinical rejection was similar between the groups, whereas interstitial fibrosis and tubular atrophy (IF/TA) were less common in the Tac-QD group at 12 months (42.2% vs 20.6%, P = .04). Univariate and multivariate logistic regression analyses revealed that allograft rejection (borderline changes or higher) was associated with IF/TA (odds ratio 4.09, 95% confidence interval 1.76–10.10, P = .001). The Tac-QD–based regimen showed a trend toward the absence of IF/TA but it did not reach statistical significance. Tubular vacuolization and arteriolar hyaline changes were also comparable in the two groups. Conclusions We found a trend toward milder IF/TA, but no significant differences in kidney allograft pathology in patients who were administered Tac-QD– versus Tac-BID–based regimens at 12 months. The effects of Tac-QD on chronic allograft injury must be studied by longer observation.
    Transplantation Proceedings 03/2014; 46(2):395–399. DOI:10.1016/j.transproceed.2013.10.050 · 0.95 Impact Factor
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    ABSTRACT: Establishment of tritium recovery system is necessary to prevent its leakage to the working area. The catalytic oxidation and adsorption process is the most valid method to recover tritium into the working area of those facilities. Therefore, there is a necessity that the tritium recovery system with large-scale and higher integrity is developed and constructed. For this purpose, it is required to obtain and accumulate updated database for chemical engineering design based on most recently commercial and available catalysts and adsorbents. In this work, we selected an adsorbent and catalysts, and examined their adsorption characteristics for water vapor. Adsorption isotherms were studied with a volumetric gas adsorption instrument. Various adsorption models were tested to correlate the experimental isotherms. For the catalyst, catalytic activity for oxidation of hydrogen was investigated in wet gas conditions. The experimental isotherms were successfully correlated using multi-site Langmuir-Freundlich equations. The catalytic activity was found to be influenced by the amount of water vapor adsorbed on the catalyst substrate.
    Fusion Engineering and Design 10/2013; 88(9-10):2408-2412. DOI:10.1016/j.fusengdes.2013.04.032 · 1.15 Impact Factor
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    ABSTRACT: We demonstrated monolithic integration of pseudo-spin-MOSFETs (PS-MOSFETs) using vendor-made MOSFETs fabricated in a low-cost multi-project wafer (MPW) product and lab-made magnetic tunnel junctions (MTJs) formed on the topmost passivation film of the MPW chip. The tunneling magnetoresistance (TMR) ratio of the fabricated MTJs strongly depended on the surface roughness of the passivation film. Nevertheless, after the chip surface was atomically flattened by SiO2 deposition and successive chemical-mechanical polish (CMP) process, the fabricated MTJs on the surface exhibited a sufficiently large TMR ratio (> 140 %) adaptable to the PS-MOSFET application. The implemented PS-MOSFETs showed clear modulation of the output current controlled by the magnetization configuration of the MTJs, and a maximum magnetocurrent ratio of 90 % was achieved. These magnetocurrent behaviors were quantitatively consistent with those predicted by HSPICE simulations. The developed integration technique using a MPW CMOS chip would also be applied to monolithic integration of CMOS devices/circuits and other various functional devices/materials, which would open the door for exploring CMOS-based new functional hybrid circuits.
    ESSDERC 2013 - 43rd European Solid State Device Research Conference; 09/2013
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    ABSTRACT: The outcomes of organ transplantation have improved due to better immunosuppressive drugs, surgical techniques, and management of complications. However, ischemia-reperfusion injury remains a challenge affecting graft survival. In this study, we employed injection of a protein transduction domain (PTD) to inhibit the c-Jun NH2-terminal kinase (JNK) pathway thereby attenuating ischemia-reperfusion injury in a porcine model. The PTD-JNK inhibitor (JNKI) was administered into the renal artery, allowing it to be taken into various elements including vascular endothelial cells by endocytosis via the PTD. Serum creatinine and blood urea nitrogen concentrations were lower among PTD-JNKI than controls. In addition, renal tissue blood flow was maintained in the PTD-JNKI group, resulting in less tissue injury and fewer apoptotic cells. These results suggested that the PTD technique improved renal transplantation outcomes.
    Transplantation Proceedings 07/2013; 45(6):2469-75. DOI:10.1016/j.transproceed.2013.02.134 · 0.95 Impact Factor
  • Pancreatology 03/2013; 13(2):e4. DOI:10.1016/j.pan.2012.12.068 · 2.50 Impact Factor
  • Pancreatology 03/2013; 13(2):e62-e63. DOI:10.1016/j.pan.2012.12.274 · 2.50 Impact Factor
  • Pancreatology 03/2013; 13(2):e74. DOI:10.1016/j.pan.2012.12.312 · 2.50 Impact Factor
  • Pancreatology 03/2013; 13(2):e12. DOI:10.1016/j.pan.2012.12.096 · 2.50 Impact Factor
  • Pancreatology 03/2013; 13(2):e24. DOI:10.1016/j.pan.2012.12.137 · 2.50 Impact Factor
  • Nihon Kikan Shokudoka Gakkai Kaiho 01/2013; 64(2):113-113. DOI:10.2468/jbes.64.113

Publication Stats

10k Citations
1,325.17 Total Impact Points

Institutions

  • 2008–2015
    • National Institute for Fusion Science
      • Department of Helical Plasma Research
      Tokitsu-chō, Gifu, Japan
  • 1996–2015
    • Kyushu University
      • • Department of Surgery and Oncology
      • • Division of Surgery
      • • Medical Hospital
      Hukuoka, Fukuoka, Japan
    • Fukuoka University
      • Department of Gastroenterology
      Hukuoka, Fukuoka, Japan
  • 1986–2013
    • The University of Tokyo
      • • Department of Electrical and Electronics Engineering
      • • Faculty & Graduate School of Medicine
      • • Institute of Industrial Science
      • • Research Center for Advanced Science and Technology
      Tōkyō, Japan
  • 2010
    • National Institutes Of Natural Sciences
      Edo, Tōkyō, Japan
    • Showa University
      • Department of Oral and Maxillofacial Surgery
      Shinagawa, Tōkyō, Japan
  • 2001–2010
    • Kobe Tokiwa University
      Kōbe, Hyōgo, Japan
    • Japan Red Cross Fukuoka Hospital
      Hukuoka, Fukuoka, Japan
    • Kyushu Rosai Hospital
      Kitakyūshū, Fukuoka, Japan
  • 1994–2010
    • Hokkaido University
      • • Faculty of Pharmaceutical Sciences
      • • Graduate School of Pharmaceutical Sciences
      Sapporo, Hokkaidō, Japan
    • Dallas Zoo
      Dallas, Texas, United States
    • Kanazawa Medical University
      • Department of Surgery II
      Kanazawa-shi, Ishikawa-ken, Japan
  • 2009
    • Tohoku University
      • Institute of Multidisciplinary Research for Advanced Materials (IMRAM)
      Sendai, Kagoshima, Japan
  • 1994–2009
    • Nara Medical University
      • Department of Urology
      Kashihara, Nara, Japan
  • 2005–2008
    • National Institute of Advanced Industrial Science and Technology
      Tsukuba, Ibaraki, Japan
  • 2004–2008
    • Kobe College
      Kōbe, Hyōgo, Japan
  • 2007
    • Center of Molecular Immunology
      La Habana, La Habana, Cuba
  • 2006
    • Japan Synchrotron Radiation Research Institute (JASRI)
      Tatsuno, Hyōgo, Japan
    • NEC Corporation
      Edo, Tōkyō, Japan
  • 1998–2006
    • University of Occupational and Environmental Health
      • Department of Obstetrics and Gynecology
      Kitakyūshū, Fukuoka, Japan
    • Osaka University
      • Research Center for Nuclear Physics
      Suika, Ōsaka, Japan
    • St. Luke's International Hospital
      Edo, Tōkyō, Japan
  • 2004–2005
    • Waseda University
      • • Graduate School of Science and Engineering
      • • Department of Applied Chemistry
      Edo, Tōkyō, Japan
  • 2001–2005
    • Osaka City University
      • Department of Biochemistry
      Ōsaka, Ōsaka, Japan
  • 2002
    • Noguchi Thyroid Clinic and Hospital Foundation
      Бэппу, Ōita, Japan
  • 2000–2002
    • Sony Corporation
      • US Research Center
      Edo, Tōkyō, Japan
  • 1993–2001
    • Tokyo Medical and Dental University
      • • Department of Pulmonary Medicine
      • • Department of Internal Medicine
      Edo, Tōkyō, Japan
    • imec Belgium
      Louvain, Flemish, Belgium
  • 1992–2001
    • National Institute for Basic Biology
      Okazaki, Aichi, Japan
    • Yamaguchi University
      Yamaguti, Yamaguchi, Japan
  • 1991–2001
    • Kanazawa University
      • • Cancer Research Institute
      • • School of Medicine
      • • Department of Urology
      Kanazawa-shi, Ishikawa-ken, Japan
  • 1991–2000
    • Asahi General Hospital
      Asahi, Chiba, Japan
  • 1999
    • Nagoya University
      • Department of Energy Engineering and Science
      Nagoya-shi, Aichi-ken, Japan
  • 1997
    • Toshiba Corporation
      Edo, Tōkyō, Japan
  • 1989–1996
    • Tokyo Metropolitan Hiroo Hospital
      • • Division of Cardiology
      • • Department of Pathology
      Edo, Tōkyō, Japan
  • 1995
    • YAMASA Corporation
      Tiba, Chiba, Japan
  • 1987–1995
    • Niigata University
      • Division of Neuropathology
      Niahi-niigata, Niigata, Japan
  • 1990–1992
    • Shinshu University
      Shonai, Nagano, Japan
    • Konan University
      • Department of Physics
      Kōbe-shi, Hyogo-ken, Japan
  • 1989–1990
    • Toyama Medical and Pharmaceutical University
      Тояма, Toyama, Japan