M J Martin

University of California, San Francisco, San Francisco, California, United States

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Publications (3)81.84 Total impact

  • M J Martin, W S Browner, S B Hulley
    The Lancet 03/1987; 1(8531):503. · 39.21 Impact Factor
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    ABSTRACT: The risks associated with various levels of serum cholesterol were determined by analysis of 6-year mortality in 361,662 men aged 35-57. Above the 20th percentile for serum cholesterol (greater than 181 mg/dl, greater than 4.68 mmol/l), coronary heart disease (CHD) mortality increased progressively; the relative risk was large (3.8) in the men with cholesterol levels above the 85th percentile (greater than 253 mg/dl, greater than 6.54 mmol/l). When men below the 20th cholesterol percentile were used as the baseline risk group, half of all CHD deaths were associated with raised serum cholesterol concentrations; half of these excess deaths were in men with cholesterol levels above the 85th percentile. For both CHD and total mortality, serum cholesterol was similar to diastolic blood pressure in the shape of the risk curve and in the size of the high-risk group. This new evidence supports the policy of a moderate fat intake for the general population and intensive treatment for those at high risk. There is a striking analogy between serum cholesterol and blood pressure in the epidemiological basis for identifying a large segment of the population (10-15%) for intensive treatment.
    The Lancet 11/1986; 2(8513):933-6. · 39.21 Impact Factor
  • S B Hulley, M J Martin
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    ABSTRACT: Over the past 15 years, efforts by the health profession to detect and treat high blood pressure have grown remarkably successful. A similar growth now seems likely for high blood cholesterol. Three factors are responsible: the continuing emergence of scientific evidence corroborating the benefit of lowering high blood cholesterol levels by diet or drugs, the formulation in 1984 of more specific health policy guidelines by the Consensus Development Conference on Lowering Blood Cholesterol and the creation in 1985 of the National Cholesterol Education Program. This program has been designed to enhance preventive activities by the public and by health care professionals. Its success will depend in part on resolving problems with the efficacy and acceptability of life-style and drug interventions for lowering blood cholesterol levels.
    The American Journal of Cardiology 07/1986; 57(16):3H-6H. · 3.43 Impact Factor

Publication Stats

559 Citations
81.84 Total Impact Points


  • 1986
    • University of California, San Francisco
      • Institute for Health Policy Studies
      San Francisco, California, United States