Are you Lili Wang?

Claim your profile

Publications (3)0 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: Use slit lamp microscope and optical microscope to observe the changes in corneal tissue after corneal epidermis injury and the effect of seawater soaking on the healing of cornea after explosive injury. Corneal epidermis were scraped on 20 eyes of 10 adult grey rabbits. For each rabbit, the right eye was in experiment and the left one was for comparison. After the injury, the experimental eyes were soaked in seawater for 30 minutes and the comparable eyes were soaked in 0.9% sodium chloride injection for the same time. All eyes were underwent slit lamp examinations, fluorescein dyeing, and ultrasonic cornea thickness metering on the corneas before the injury and 1, 3, 5, 7, 10 days after the injury respectively. At the same time, 2 rabbits were killed and the eyes were examined with pathology. The cornea thickness numbers were compared using self-comparison t test and grouping t test. Result after scraping the whole corneal epidermis, slit lamp microscope examination found that the corneas were edema and turbidity, the experimental eyes were stricter than the comparable eyes. The corneas of the experimental eye were vascularized 10 days after the injury. Fluorescein dyeing showed that more apparent pigmentation was found on the experimental eyes than that on the comparable ones. Comparative examination under the optical microscope showed that the corneal tissue of the experiment eyes changed distinctly, its inflammation is patency and healing was delayed and the vascularization degree became high after the injury. Cornea thickness of the experimental eyes became apparently thicker than that of the comparable eyes. The difference was statistically significant. Seawater soaking will have bad effects on the healing of the corneal epidermis injury.
    Yan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu 01/2006; 21(4):149-52.
  • [Show abstract] [Hide abstract]
    ABSTRACT: To explore the pathological changes of retinal ganglion cell apoptosis and its relation to the value of glutamate concentration in vitreous body after explosive injury of eyeballs in the rabbits. Similar explosive injury models of eyeballs in 10 adult grey rabbits were made. The rabbits were killed on scheduled time. The retinal tissues of studied eyes and control eyes were obtained for the pathological examination with TUNEL method respectively. The value of glutamate in vitreum of injured eyes was measured and was compared with that of contralateral eyes. Statistical comparison analysis on the experiment data was performed. The value of glutamate in vitreum of injured eyes was significantly higher than that of contralateral eyes in all rabbits in the study. A lot of TUNEL positive cells were observed in the injured eyes. It suggested that apoptosis of the retinal ganglion cells took place. We speculate that apoptosis of the retinal ganglion cells is perhaps among the causes resulting in damage of visual function after explosive injury of eyeballs and that the increasing of the value of glutamate in vitreum possibly associated with apoptosis of the retinal ganglion cells.
    Yan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu 10/2003; 19(3):187-90.
  • [Show abstract] [Hide abstract]
    ABSTRACT: To observe the changes in corneal tissue after explosive corneal injury and the effect of seawater soaking on the healing of cornea after explosive injury with the help of optical microscope. Make 10 similar explosive injury models of rabbit's eyeball using 10 adult grey rabbits. For each rabbit, both eyes are artificially injured through explosion; its right eye is the comparison eye and after the injury the left eye is soaked in seawater for 30 minutes. (Conduct slit lamp examinations, fluorescein dyeing, and ultrasonic cornea thickness metering on the corneas at intervals, that is, before the injury, 1, 2, 3, 4, 5, 7, 9, 12, 15 days after the injury respectively. Examine the corneas under the optical microscope and make comparisons. The corneal thickness of the experiment eye becomes apparently thicker than that of the comparison eye after the injury. The corneal clouding of the former apparently aggravates compared with the latter. The healing of corneal epithelium in the injured eye is slower compared with that in the comparison eye. Comparative examination under the optical microscope shows: after the injury, the corneal tissue of the experiment eye changes distinctly, its healing is delayed and the vascularization degree becomes high in corneal stroma. Scars and vascularization of various degrees will appear in corneal stroma after explosive injuries. Seawater soaking will have bad effects on the healing of the cornea injured in explosions.
    Yan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu 04/2002; 18(1):59-62.