Li Wang

Nanjing University of Aeronautics & Astronautics, Nan-ching, Jiangsu Sheng, China

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Publications (815)2338.91 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: Metal or metal oxides/graphene nanocomposites with porous structures have become one of the most promising functional materials in sensor, catalysis, energy conversion, etc. In this work, novel porous Co nanobeads/reduced graphene oxide (rGO) nanocomposites are fabricated based on metal-organic frameworks (MOFs)-templated method. In this strategy, benzoic acid groups are initially grafted on rGO via CC bond to form benzoic acid-functionalized rGO (BFrGO), then the BFrGO/CoMOFs is constructed by alternately immersing BFrGO in Co2+ and 1,3,5-benzentricarboxylic acid solution based on a step-by-step route. The novel porous Co nanobeads/rGO nanocomposites are fabricated by pyrolyzing the corresponding BFrGO/CoMOFs. Based on the as-formed Co nanobeads/rGO nanocomposites, a novel nonenzymatic glucose sensor is developed. The porous and hierarchical superstructures, good electrical conductivity and large specific surface area of Co nanobeads/rGO nanocomposites eventually contributed to the good performance of the resulted sensor towards the detection of glucose. The proposed preparation method of Co nanobeads/rGO nanocomposites is simple and might open up a new way for hierarchical superstructures preparation.
    Sensors and Actuators B Chemical 12/2015; 220:1056-1063. DOI:10.1016/j.snb.2015.06.052 · 4.29 Impact Factor
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    ABSTRACT: Flag leaf is the most essential organ for photosynthesis in rice and its size plays an important role in rice breeding for ideal plant-type. Flag leaf size affect photosynthesis to a certain extent, thereby influencing rice production. Several genes controlling leaf size and shape have been identified with mutants. Although a number of quantitative trait loci (QTLs) for leaf size and shape have been detected on 12 chromosomes with different populations of rice, few of them were cloned. The pair-wise correlation analysis was conducted on length, width and length-width ratio of the flag leaf, and yield per plant in the core recombinant inbred lines of Liang-You-Pei-Jiu (LYP9) developed in Hainan and Hangzhou. There were significant correlations among the three flag leaf size and shape traits. Interestingly, a positive correlation was found between flag leaf width and yield per plant. Based on the high-resolution linkage map we constructed before, 43 QTLs were detected for three flag leaf size and shape traits and yield per plant, among which 31 QTLs were unreported so far. Seven QTLs were identified common in two environments. And qFLW7.2, a new major QTL for flag leaf width, was fine mapped within 27.1 kb region on chromosome 7. Both qFLW7.2 and qPY7 were located in the interval of 45.30 ~ 53.34 cM on chromosome 7, which coincided with the relationship between yield per plant (PY) and flag leaf width (FLW). qFLW7.2, which explained 14% of the phenotypic variation, increased flag leaf width with 93-11 allele. Two candidate genes were selected based on sequence variation and expression difference between two parents, which facilitated further QTL cloning and molecular breeding in super rice.
    Rice 12/2015; 8(1). DOI:10.1186/s12284-014-0039-9 · 2.45 Impact Factor
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    ABSTRACT: In 1929, Donald Othmer discovered that a small amount of non-condensable gases (NCG) in pure vapor had a great effect on condensation heat transfer coefficient (HTC), reducing the efficiency of heat transfer equipment. Since then, a large amount of research has been performed. This paper reviews experimental, mechanism and model research progresses in condensation in the presence of NCG. Particular attention is given to research on physical models of heat transfer for filmwise condensation (FWC) with NCG, with a brief review of dropwise condensation (DWC). The models for FWC heat transfer in the presence of NCG can be divided into two categories: semi-theoretical models and theoretical models. The semi-theoretical models are based on hydraulics and thermodynamics, use some specific parameters of the correlation which determined by experiments, and are suitable for engineering design. The theoretical models are based on mass, momentum, and energy conservation equations, and divided into boundary layer models and diffusion layer models. Through research of experiments and models people found that, condensate film thickness, surface waves, interfacial shear strength and suction effect play an important role in the FWC heat transfer in presence of NCG.
    Applied Thermal Engineering 10/2015; 89. DOI:10.1016/j.applthermaleng.2015.06.040 · 2.62 Impact Factor
  • Kun He, Hongliang Zhu, Li Wang
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    ABSTRACT: Inspired by energy storage systems for peak load shifting (PLS), this study proposes a PLS utilization mode of electricity-generating coal gas resources for the steel industry in China. The proposed mode can help the steel industry save electricity bills (2.4%) through the introduction of a time-of-use tariff. Data of a steel enterprise are used to prove the economic benefit of the coal gas utilization mode. Given that China produces more than half of converter steel of the total production worldwide, their coal gas resources are abundant. The PLS utilization mode will have a great effect on balancing the power grid. A simulated operation model for PLS coal-fired power units is used to calculate the energy conservation and emission reduction effect of coal-fired power plants under different scenarios. The annual coal savings are 1.7–3.1%, and the annual SO2 and NOX emission reductions are 2.9–12.4% and 44.6–14.1% of the total reduction amount of the steel industry in China, respectively.
    Applied Energy 09/2015; 154:644-650. DOI:10.1016/j.apenergy.2015.05.022 · 5.26 Impact Factor
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    ABSTRACT: The detection of glucose has been attracting more and more attention. The present work provided a novel glucose sensor based on hierarchical NiO superstructures/foam Ni electrode. In this strategy, the foam Ni was chosen as a substrate to grow Ni metal-organic frameworks (NiMOFs) via “twin metal source” method, and then the hierarchical NiO superstructures/foam Ni electrode was constructed by pyrolyzing the corresponding NiMOFs/foam Ni electrode for the first time. The preparation process was carefully characterized by scanning electron microscopy, thermogravimetric analysis and X–ray powder diffraction. The results showed the NiMOFs on foam Ni electrode with morphology of the flakes. After the NiMOFs/foam Ni electrode was pyrolyzed, the hierarchical NiO superstructures/foam Ni electrode was formed and the hierarchical NiO superstructures uniformly embedded in three-dimensional carbon frameworks to enhance the electrical conductivity of hierarchical NiO superstructures. The electrocatalytic properties of hierarchical NiO superstructures/foam Ni electrode were investigated by cyclic voltammetry, amperometry and chronoamperometry. The novel glucose sensor showed a reasonable linear range of 0.018–1.2 mM and detection limit of 6.15 μM with a high sensitivity of 395 μA mmol−1. Such good result renders it promising candidate for routine testing.
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    ABSTRACT: Promoting both endogenous and exogenous neural stem cells (NSCs) survival in the hostile host environments is essential to cell replacement therapy for central nervous system (CNS) disorders. Type 4 metabotropic glutamate receptor (mGluR4), one of the members of mGluRs, has been showed to protect neurons from acute and chronic excitotoxic insults in various brain damages. The present study investigated the preventive effects of mGluR4 on NSC injury induced by oxidative stress. Under challenge with H2O2, loss of cell viability was observed in cultured rat NSCs, and treatment with selective mGluR4 agonist VU0155041 conferred protective effects against the loss of cellular viability in a concentration-dependent manner, as shown by MTT assay. Pretreatment of VU0155041 (30 μM) also inhibited the excessive NSC death induced by H2O2, and group III mGluR antagonist MSOP or gene-targeted knockdown abolished the protective action of mGluR4, indicated by PI/Hoechst and TUNEL staining. Western blot assay demonstrated that mGluR4 activation reversed the decreased pro-caspase-8/9/3 and the destructed Bcl-2/Bax expressing balance, and likewise, MSOP and mGluR4 knockdown abrogated the action of mGluR4 activity. Furthermore, inhibition of JNK and p38 mitogen-activated protein kinases (MAPKs) were observed after mGluR4 activation, and as paralleling control, JNK-specific inhibitor SP600125 and p38-specific inhibitor SB203580 significantly rescued the H2O2-mediated NSC apoptosis and cleavage of procaspase-3. We suggest that activation of mGluR4 prevents oxidative stress-induced NSC death and apoptotic-associated protein activities with involvement of inhibiting the JNK and p38 pathways in cell culture. Our findings may help to develop strategies for enhancing the resided and transplanted NSC survival after oxidative stress insult of CNS. Key words: metabotropic glutamate receptor 4; neural stem cells; oxidative stress; hydrogen peroxide; apoptosis.
    Stem cells and development 07/2015; DOI:10.1089/scd.2015.0067 · 4.20 Impact Factor
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    ABSTRACT: Secreted protein acidic and rich in cysteine (SPARC) has a complex and pleiotropic biological role in cell life during disease. The role of SPARC in myelodysplastic syndrome (MDS) is not yet fully understood. In the present study, we investigated the role of SPARC protein overproduction in the proliferation and apoptosis of SKM-1 cells, an acute myeloid leukemia cell line transformed from MDS. SKM-1 cells were infected with the pGC-GV-SPARC vector. The cells were then assessed for proliferation and cell death following treatment with low-dose cytosine arabinoside (Ara‑C). The microarray analysis results revealed that samples from SPARC‑overexpressed cells compared to SPARC protein, in SKM-1 cells led to proliferation inhibition and promoted programmed cell death and these effects were greater when treated with Ara-C. The mRNA and protein expression levels of SPARC were detected by SPARC overexpression in cells treated with Ara-C resulting in a significant upregulation of the mixed lineage kinase domain-like (MLKL) gene expression and five other genes. The results showed that the necrotic signaling pathway may play a role when the two conditions were combined via the upregulation of the MLKL protein. MLKL upregulation in SPARC overexpressed cells treated with Ara-C, indicates necrosis as a possible cell death process for the SKM-1 cells under these stringent conditions.
    Oncology Reports 07/2015; DOI:10.3892/or.2015.4114 · 2.19 Impact Factor
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    ABSTRACT: Distant metastasis and local recurrence are still the major causes for failure of treatment in patients with nasopharyngeal carcinoma (NPC), making it urgent to further elicit the molecular mechanisms of NPC metastasis. Using a gene microarray including transcription factors and known markers for cancer stem cells, prostate stem cell antigen (PSCA) was found to be significantly down-regulated in metastatic NPC in lymph node, compared to its primary tumor, and in NPC cell lines with high metastatic ability compared to those with low metastatic ability. NPC patients with low PSCA expression had a consistently poor metastasis-free survival (p = 0.003). Knockdown and overexpression of PSCA respectively enhanced and impaired the migration and invasion in vitro and the lung metastasis in vivo of NPC cells. Mechanistically, the enhancement of NPC metastasis by knocking down PSCA probably involved epithelial-mesenchymal transition (EMT), by up-regulating N-cadherin and ZEB1/2 and by activating Rho A. The down-regulation of PSCA in NPC cells resulted directly from the binding of Slug to the PSCA promoter. PSCA may be a potential diagnostic marker and therapeutic target for patients with NPC. This article is protected by copyright. All rights reserved.
    The Journal of Pathology 07/2015; DOI:10.1002/path.4582 · 7.33 Impact Factor
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    ABSTRACT: We investigated whether the MDR1 (multidrug resistance 1) gene single nucleotide polymorphism (SNP) and haplotype variants were associated with the susceptibility to diffuse large B-cell lymphoma (DLBCL). A total of 129 DLBCL patients and 208 healthy controls from Jiangsu Han population were enrolled in this study. They were genotyped by polymerase chain reaction-allele specific primers (PCR-ASP) method or DNA direct sequencing at three common loci: C1236T, G2677T/A and C3435T. At locus G2677T/A, allele G and genotype GT were significantly more common in DLBCL (G: OR=1.48, 95% CI: 1.08-2.02, Pc=0.03; GT: OR=1.96, 95% CI: 1.25-3.07, Pc<0.01), while genotype AT in this locus seemed to be protective (OR=0.29, 95% CI: 0.02-0.72, Pc=0.03). TT genotype at locus C3435T showed a risk factor in DLBCL (OR=2.38, 95% CI: 1.52-3.74, Pc<0.01). The frequency of T-G-T haplotype was significantly increased in DLBCL group (OR=5.21, 95% CI: 2.58-10.54, Pc<0.01); haplotype of G-T in 2677-3435 and diplotype of 2677GT/3435TT were significantly more frequent in DLBCL group (G-T: OR=3.97, 95% CI: 2.31-6.85, Pc<0.01; 2677GT/3435TT: OR=4.55, 95% CI: 2.02-10.22, Pc<0.01). Our findings demonstrate that G, GT at locus G2677T/A, and TT at locus C3435T might contribute to the susceptibility to DLBCL, as well as haplotype of T-G-T, G-T in 2677-3435 and diplotype of 2677GT/3435TT, while AT at locus G2677T/A might be a protective genotype. These findings could provide evidence that the MDR1 SNPs may modify the susceptibility to DLBCL and shade new lights in disease association studies. Copyright © 2015 Elsevier Masson SAS. All rights reserved.
    Biomedecine [?] Pharmacotherapy 07/2015; 73:24-28. DOI:10.1016/j.biopha.2015.05.005 · 2.11 Impact Factor
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    ABSTRACT: Non-coding microRNAs (miRNAs), involved in post-transcriptional control, are widely involved in the mechanism of cellular resistance to antitumor chemotherapy. Ectopic expression of one of these miRNAs, miRNA‑215 (miR‑215), leads to chemoresistance by directly targeting dihydrofolate reductase (DHFR) and thymidylate synthase (TS), which are two of the most important targets of chemotherapeutic agents. This indicates the possible upregulation of endogenous miR‑215 in the process of chemoresistance by interfering with important transcripts. In the present study, the upregulation of miR‑215 was examined in hepatocellular carcinoma (HCC) subcell lines, Adriamycin (ADM)‑resistant HepG2 (HepG2/AR), Hep3B (Hep3B/AR) cell lines, and in ADM‑treated patients with HCC. Upregulated miR‑215 directly targeted DHFR and TS mRNA and reduced their protein expression levels, without altering mRNA levels. The ectopic expression of miR‑215 anti‑sense oligo‑nucleotides in HepG2/AR and Hep3B/AR cells enhanced chemosensitivity, whereas the expression of the miR‑215 mimics led to chemoresistance. Notably, the upregulation of miR‑215 indirectly increased the protein levels of P53 and P21 levels in the HepG2 cells, which contain functional P53, which is expected to result in the inhibition of proliferation and colony formation. Taken together, the present study demonstrated that the upregulation of miR‑215 resulting from ADM treatment in HCC cells leads to the development of insensitivity to ADM and worsens the prognosis of patients with HCC exhibiting mutated P53.
    Molecular Medicine Reports 07/2015; DOI:10.3892/mmr.2015.4012 · 1.48 Impact Factor
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    ABSTRACT: To characterize the clinical features of IgG4-related disease (IgG4-RD) in China. A prospective cohort study of IgG4-RD was carried out in Peking Union Medical College Hospital between 2011 and 2013. Patients with newly diagnosed IgG4-RD were enrolled. A total of 118 patients with IgG4-RD were enrolled, including 82 males and 36 females, aged 53.1 (s.d. 13.6) years. The most common symptom at onset was lacrimal gland swelling (38/32.2%). A range of organs were involved: 77 patients (65.3%) had lymphadenopathy, 76 (64.4%) had sialadenitis, 60 (50.8%) had dacryoadenitis, 45 (38.1%) had autoimmune pancreatitis, 32 (27.1%) had pulmonary involvement, 31 (26.3%) had periaortitis/retroperitoneal fibrosis, 29 (35.4% of male patients) had prostatitis and 29 (24.6%) had renal involvement. In addition, there were 21 (17.8%) cases of sclerosing cholangitis, 15 (12.7%) of sinusitis and 10 (8.5%) of inflammatory pseudotumour. Uncommon manifestations included mediastinal fibrosis, skin involvement, sclerosing thyroiditis, hypophysitis, orchitis and colitis. Multiple organ involvement was observed in 93 patients, whereas only 4.2% had only a single organ involved. A history of allergy was reported in 73 (61.9%) patients. The serum IgG4 level was elevated in 97.5% and was correlated with the number of organs involved. Most patients were treated with glucocorticoids alone or in combination with immunosuppressive drugs, and the majority usually improved within 3 months. IgG4-RD is a systemic inflammatory and sclerosing disease. Parotid and lacrimal involvement (formerly called Mikulicz's disease), lymphadenopathy and pancreatitis are the most common manifestations. Patients with IgG4-RD showed favourable responses to treatment with glucocorticoids and immunosuppressive agents. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email:
    Rheumatology (Oxford, England) 06/2015; DOI:10.1093/rheumatology/kev203 · 4.44 Impact Factor
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    ABSTRACT: A hydrothermal process of zinc oxide (ZnO), which was suitable for both planar surfaces and non-planar surfaces, was proposed to obtain nanopillars in this work. The effects of process parameters including the growth time and solution concentration on the morphological properties of ZnO nanorods were investigated by experiments. After process optimization, the ZnO arrays were well patterned in large area with vertically aligned orientation. This developed process of ZnO was then introduced to combine with other techniques to obtain various hierarchical structures on different substrates. Furthermore, the superhydrophobicity and self-cleaning effect were respectively verified on the plexiglass tube with ZnO nanopillars and the tin–bronze surface with hierarchical architectures.
    Microelectronic Engineering 06/2015; 141. DOI:10.1016/j.mee.2015.01.015 · 1.34 Impact Factor
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    ABSTRACT: A novel glucose biosensor was developed by immobilizing glucose oxidase (GOD) on a three-dimensional (3D) porous kenaf stem-derived carbon (3D-KSC) which was firstly proposed as novel supporting materials to load biomolecules for electrochemical biosensing. Here, an integrated 3D-KSC electrode was prepared by using a whole piece of 3D-KSC to load the GOD molecules for glucose biosensing. The morphologies of integrated 3D-KSC and 3D-KSC/GOD electrode were characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The SEM results revealed 3D honeycomb macroporous structure of integrated 3D-KSC electrode. The TEM results showed some microporosities and defects in the 3D-KSC electrode. The electrochemical behaviors and electrocatalytic performance of integrated 3D-KSC/GOD electrode were evaluated by cyclic voltammetry and electrochemical impedance spectroscopy. The effects of pH and scan rate on the electrochemical response of biosensor have been studied in detail. The glucose biosensor showed a wide linear range from 0.1 mM to 14.0 mM with a high sensitivity of 1.73 μA mM-1 and a low detection limit of 50.75 μM. Furthermore, the glucose biosensor exhibited high selectivity, good repeatability and reproducibility, and nice stability.
    The Analyst 06/2015; DOI:10.1039/C5AN00200A · 3.91 Impact Factor
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    ABSTRACT: In clinical practical work, a rare kind of chronic pancreatic inflammatory granuloma which is caused by the foreign body of gastrointestinal perforation could be misdiagnosed and treated as pancreatic neoplasm sometimes, and even brings irreparable harm to patients. Here, we depict a male presenting recurrent upper abdominal pain and gradual weight loss, besides, the computer tomography suggested pancreatic tumor strongly. Fortunately, it has been proved to be a chronic pancreatic inflammatory granuloma caused by fish bone through laparotomy finally. To our knowledge, this case is the first case about the chronic pancreatic inflammatory granuloma caused by foreign body which successfully avoids unnecessary pancreatectomy. Copyright © 2015. Published by Elsevier B.V.
    Pancreatology 06/2015; DOI:10.1016/j.pan.2015.05.474 · 2.50 Impact Factor
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    ABSTRACT: This study was to explore the characteristics of anemia in Castleman disease (CD). Clinical data were collected retrospectively to analyze the prevalence and characteristics of CD with anemia were analysed retrospectively, and different types of anemia and their therapeutic effects were evaluated. Anemia was observed in 13/33(39%) newly diagnosed CD patients, most of them was mild and normocytic. Incidence of anemia in multicentric CD (MCD) was higher than that in unicentric CD (UCD) (85% vs 10%, P < 0.001). Most of CD patients with anemia presented systematic manifestations; moreover, they had higher levels of erythrocyte sedimentation and inflammatory indices, higher incidence of polyclonal hyperimmunoglobulinemia, and higher positive rate of autoantibodies than those without anemia (P < 0.05). Except for 2 cases of autoimmune hemolytic anemia (AIHA) and 1 case of anemia secondary to hypersplenism, the anemia in the other 10 patients exhibited features similar to anemia of chronic disease (ACD), whose hemoglobin levels were negatively correlated with the serum levels of C reactive protein and fibrinogen (r -0.917 and -0.717, respectively, P < 0.001). Anemia in UCD was cured by the removal of tumor. Yet, anemia in MCD was improved after systemic treatment with immunotherapy and/or chemotherapy. anemia with an inflammatory and immunologic mechanism presents as a common symptom in MCD, but also can be observed in UCD. In addition to occasional AIHA, anemia associated with CD mainly presents characteristics of ACD. Treatment for anemia in CD is mainly based on the control of primary disease.
    Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 06/2015; 23(3):696-701.
  • PLoS ONE 05/2015; 10(5):e0128763. DOI:10.1371/journal.pone.0128763 · 3.53 Impact Factor
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    ABSTRACT: Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma (NHL). Patients with DLBCL harboring MYC aberrations concurrent with BCL2 or/and BCL6 aberrations constitute a specific group with extremely poor outcome. In this study, we retrospectively investigated the incidence and prognosis of MYC, BCL2, and BCL6 aberrations with DLBCL patients in Chinese population. We applied fluorescence in situ hybridization and immunohistochemical analysis in 246 DLBCL patients. The results showed that patients with MYC or BCL2 copy number aberration (CNA) had significantly worse overall survival (OS) and progression-free survival (PFS) than negative cases (P < 0.0001). Patients with both MYC and BCL2 CNA had similar outcomes to those with classic double hit lymphoma or protein double expression lymphoma (MYC and BCL2/BCL6 coexpression). By multivariate analysis, MYC CNA, BCL2 CNA and double CNA were the independent worse prognostic factors. In conclusions, patients with MYC or BCL2 CNA constituted a unique group with extremely poor outcome and may require more aggressive treatment regimens.
    Oncotarget 05/2015; · 6.63 Impact Factor
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    ABSTRACT: The role of 18F-2-fluoro-2-deoxy-D-glucose (FDG) uptake of bone marrow (BM) on positron emission tomography/computed tomography (PET/CT) in patients with lymphoma-associated hemophagocytic lymphohistiocytosis (LA-HLH) remains uncertain. In this retrospective study, we included 34 LA-HLH patients underwent both PET/CT and comprehensive BM examinations prior to treatment. Comparison between PET/CT and BM examinations for the assessment of bone marrow involvement (BMI) indicated statistical difference (P=0.039). The specificity of PET/CT in detecting BMI was 11.1% compared to BM examinations. However, we found a significant correlation between PET parameters of BM and laboratory parameters associated with HLH, such as C-reactive protein, ferritin, fibrinogen and soluble CD25. By multivariate analysis, PET parameters of marrow were significantly associated with overall survival. Our findings suggest that FDG uptake of marrow might fail to detect lymphomatous BMI, but reflected the level of cytokines storm to a certain extent and might be as prognostic factor in patients with LA-HLH.
    Leukemia & lymphoma 05/2015; DOI:10.3109/10428194.2015.1048442 · 2.61 Impact Factor
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    ABSTRACT: Bulk hierarchical nanoporous palladium (BHNPP) materials composing both bimodal porous structure and monolithic porous structure were fabricated by chemical dealloying of Pd20Al80 alloy with sub-micrometer grain size via mechanical alloying and spark plasma sintering process (MA-SPS). The different nanoporous structures were formed in the regions where the microstructure was heterogeneous. Monolithic porous structure were formed after dealloyed of monolithic grain structure mainly composed of PdAl3 phase, and bimodal porous structure with both larger pore of hundreds nanometers and smaller pore of a few nanometers were obtained after dealloyed of nanocrystalline structure consist of PdAl3 and Al phases, respectively. Effects of dealloying time, concentration of dealloying solutions and chloride ion (Cl−) on the evolution of the microstructure of BHNPP were also studied. Ligament of BHNPP can be facility coarsen by add chloride rather than only raise the concentration of HCl solution. Moreover, the cyclic voltammetry results reveal that the BHNPP materials have superior ethanol oxidation ability.
    Microporous and Mesoporous Materials 05/2015; 208. DOI:10.1016/j.micromeso.2015.01.017 · 3.21 Impact Factor
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    ABSTRACT: Two-dimensional materials such as MoS2 have attracted much attention in recent years due to their fascinating optoelectronic properties. Dielectric property of MoS2 is desired for the optoelectronic application. In this paper, terahertz (THz) time-domain spectroscopy and ellipsometry technology are employed to investigate the dielectric response of MoS2 crystal in THz and visible region. The real and imaginary parts of the complex dielectric constant of MoS2 crystal are found to follow a Drude model in THz region, which is due to the intrinsic carrier absorption. In visible region, the general trend of the complex dielectric constant is found to be described with a Lorentz model, while two remarkable peaks are observed at 1.85 and 2.03 eV, which have been attributed to the splitting arising from the combined effect of interlayer coupling and spin-orbit coupling. This work affords the fundamental dielectric data for the future optoelectronic applications with MoS2.

Publication Stats

8k Citations
2,338.91 Total Impact Points


  • 2015
    • Nanjing University of Aeronautics & Astronautics
      • College of Mechanical and Electrical Engineering
      Nan-ching, Jiangsu Sheng, China
  • 2014–2015
    • 307 Hospital of the Chinese People's Liberation Army
      Peping, Beijing, China
    • Qingdao University of Science and Technology
      Tsingtao, Shandong Sheng, China
    • Shanghai Institute of Technology
      Shanghai, Shanghai Shi, China
    • China National Rice Research Institute
      Hang-hsien, Zhejiang Sheng, China
    • Nanjing University of Traditional Chinese Medicine
      Nan-ching, Jiangsu Sheng, China
    • Beijing Jiaotong University
      • School of Traffic and Transportation
      Peping, Beijing, China
    • Zhengzhou University
      Cheng, Henan Sheng, China
    • McMaster University
      • Department of Anesthesia
      Hamilton, Ontario, Canada
  • 2013–2015
    • Harbin Medical University
      • College of Bioinformatics Science and Technology
      Charbin, Heilongjiang Sheng, China
    • Xuzhou Medical College
      Suchow, Jiangsu Sheng, China
    • Guilin University of Electronic Technology
      Ling-ch’uan, Guangxi Zhuangzu Zizhiqu, China
    • Shangqiu Normal University
      Zhuji, Henan Sheng, China
    • First People's Hospital Chenzhou
      Chenchow, Hunan, China
    • Beijing University of Posts and Telecommunications
      • Department of Communication Engineering
      Peping, Beijing, China
    • Hangzhou Normal University
      Hang-hsien, Zhejiang Sheng, China
    • Inner Mongolia University
      Suiyüan, Inner Mongolia, China
    • Capital Medical University
      • Department of Pathophysiology
      Peping, Beijing, China
  • 2012–2015
    • Sun Yat-Sen University Cancer Center
      • Department of Radiation Oncology
      Shengcheng, Guangdong, China
    • Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
      Hua-yang, Sichuan, China
    • Shanxi Medical University
      • Department of Physiology
      Yangkü, Shanxi Sheng, China
    • South China Agricultural University
      • College of Food Science
      Shengcheng, Guangdong, China
    • Chongqing University of Technology
      Ch’ung-ch’ing-shih, Chongqing Shi, China
  • 2011–2015
    • Nantong University
      Tungchow, Jiangsu Sheng, China
    • Chongqing Medical University
      Ch’ung-ch’ing-shih, Chongqing Shi, China
    • Chinese PLA General Hospital (301 Hospital)
      Peping, Beijing, China
    • Xi'an Jiaotong University
      • • School of Mechanical Engineering
      • • State Key Laboratory for Mechanical Behavior of Materials
      • • School of Medicine
      • • State Key Laboratory for Manufacturing Systems Engineering
      Ch’ang-an, Shaanxi, China
    • Beijing Institute of Microbiology and Epidemiology
      Peping, Beijing, China
    • Huazhong University of Science and Technology
      • State Key Laboratory of Digital Manufacturing Equipment and Technology
      Wu-han-shih, Hubei, China
    • Tsinghua University
      • State Key Joint Laboratory of Environmental Simulation and Pollution
      Peping, Beijing, China
    • Southwest University in Chongqing
      Pehpei, Chongqing Shi, China
    • Soochow University (PRC)
      Wu-hsien, Jiangsu Sheng, China
    • Southwest Petroleum University
      Hua-yang, Sichuan, China
  • 2010–2015
    • Lanzhou University
      • • School of Physical Science and Technology
      • • School of Life Science
      Kao-lan-hsien, Gansu Sheng, China
    • Hebei University of Science and Technology
      Chentow, Hebei, China
    • China Agriculture University-East
      Peping, Beijing, China
    • Tohoku University
      • Department of Applied Chemistry
      Miyagi, Japan
  • 2009–2015
    • Henan Provincial People’s Hospital
      Cheng, Henan Sheng, China
    • Nanjing Medical University
      • • Department of Oncology
      • • Department of Hematology
      Nan-ching, Jiangsu Sheng, China
    • Peking University
      • Institute of Urology
      Beijing, Beijing Shi, China
    • Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
      Shanghai, Shanghai Shi, China
    • Agricultural University Of Hebei
      Pao-ting-shih, Hebei, China
  • 2008–2015
    • Jiangxi Normal University
      Nan-ch’ang-shih, Jiangxi Sheng, China
    • University of Science and Technology, Beijing
      Peping, Beijing, China
    • South China University of Technology
      Shengcheng, Guangdong, China
  • 2006–2015
    • Chinese Academy of Medical Sciences
      Peping, Beijing, China
  • 2005–2015
    • Sichuan University
      • • Department of Material Science
      • • State Key Laboratory of Biotherapy
      • • Analytical Center
      • • Department of Chemistry
      • • College of Life Sciences
      Hua-yang, Sichuan, China
    • Beijing Hospital
      Peping, Beijing, China
    • University of Connecticut
      Storrs, Connecticut, United States
    • Institute of Genetics and Developmental Biology, CAS
      Peping, Beijing, China
  • 2002–2015
    • Third Military Medical University
      • • Department of Physiology
      • • Southwest Hospital
      Ch’ung-ch’ing-shih, Chongqing Shi, China
  • 2013–2014
    • China Agricultural University
      • State Key Laboratory for Agrobiotechnology
      Peping, Beijing, China
  • 2012–2014
    • Tianjin University
      • School of Science
      T’ien-ching-shih, Tianjin Shi, China
  • 2011–2014
    • Dalian Medical University
      • • College of Pharmacy
      • • School of Pharmacy
      • • Department of Pharmacology
      Lü-ta-shih, Liaoning, China
  • 2010–2014
    • Broad Institute of MIT and Harvard
      • Genome Sequencing and Analysis Program
      Cambridge, Massachusetts, United States
  • 2009–2014
    • Beijing University of Aeronautics and Astronautics (Beihang University)
      • School of Economics and Management
      Peping, Beijing, China
  • 2005–2014
    • Peking Union Medical College Hospital
      • Department of Rheumatology
      Peping, Beijing, China
    • Jilin University
      • • State Key Laboratory of Supramolecular Structure and Materials
      • • Department of Phathogenobiology
      • • State Key Laboratory of Inorganic Synthesis and Preparative
      • • Department of Immunology
      • • College of Chemistry
      Yung-chi, Jilin Sheng, China
  • 2004–2014
    • Shanghai Jiao Tong University
      • • Department of Anesthesiology
      • • Institute of Engineering Mechanics
      Shanghai, Shanghai Shi, China
    • Academy of Military Medical Sciences
      T’ien-ching-shih, Tianjin Shi, China
    • State Key Laboratory of Medical Genetics of China
      Ch’ang-sha-shih, Hunan, China
    • National Space Science
      Peping, Beijing, China
  • 2011–2013
    • Harbin Institute of Technology
      • Department of Automatic Measurement and Control Engineering
      Charbin, Heilongjiang Sheng, China
    • Jilin Normal University
      Yung-chi, Jilin Sheng, China
    • Shandong University of Science and Technology
      Tsingtao, Shandong Sheng, China
  • 2010–2013
    • Inner Mongolia Agricultural University
      Suiyüan, Inner Mongolia, China
    • University of Southampton
      • Faculty of Physical and Applied Sciences
      Southampton, England, United Kingdom
  • 2009–2013
    • Yunnan Agricultural University
      Panlong, Shaanxi, China
    • Fourth Military Medical University
      • • Department of Neurology
      • • Department of Biochemistry and Molecular Biology
      • • State Key Laboratory of Cancer Biology
      • • Department of Physiology
      Xi’an, Liaoning, China
  • 2004–2013
    • Fudan University
      • • Department of Chemistry
      • • Institute of Biodiversity Science
      • • School of Computer Science
      • • School of Life Sciences
      Shanghai, Shanghai Shi, China
  • 2003–2013
    • Chinese Academy of Sciences
      • • Institute of Physics
      • • State Key Laboratory of Organic Geochemistry
      • • Institute of Mountain Hazards and Environment
      • • Institute of Genetics and Developmental Biology
      • • State Key Laboratory of Electroanalytical Chemistry
      Peping, Beijing, China
  • 2011–2012
    • Chengdu University Of Traditional Chinese Medicine
      Hua-yang, Sichuan, China
  • 2008–2012
    • Beijing Fuwai Hospital
      Peping, Beijing, China
  • 2010–2011
    • Ocean University of China
      Tsingtao, Shandong Sheng, China
  • 2008–2011
    • Shandong University
      • School of Environmental Science and Engineering
      Chi-nan-shih, Shandong Sheng, China
    • Shanghai Center for Bioinformation Technology
      Shanghai, Shanghai Shi, China
  • 2009–2010
    • Kunming Medical College
      • Department of Pathology
      Yün-nan, Yunnan, China
  • 2008–2010
    • Second Military Medical University, Shanghai
      Shanghai, Shanghai Shi, China
  • 2007–2010
    • Technical Institute of Physics and Chemistry
      Peping, Beijing, China
    • West China School of Medicine
      Hua-yang, Sichuan, China
    • Beijing Cancer Hospital
      Peping, Beijing, China
  • 2004–2008
    • Huazhong Agricultural University
      • College of Life Science and Technology
      Wuhan, Hubei, China
  • 2005–2007
    • Shanghai University of Engineering Science
      Shanghai, Shanghai Shi, China