Li Wang

Northwest Institute of Plateau Biology, Hsi-ning-shih, Qinghai Sheng, China

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Publications (830)1814.6 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: A non-synonymous single-nucleotide polymorphism (SNP) (rs2228226C>G), in exon 12 of glioma-associated oncogene homolog 1 (GLI1) (Q1100E), encodes a change from glutamine to glutamic acid (Q1100E). The variant GLI1 protein exhibited reduced transactivation function in vivo, decreasing the ability of activating hedgehog signal, which has been proposed as an unfavorable prognostic marker in chronic lymphocytic leukemia (CLL). The GLI1 Q1100E (NCBI SNP ID: rs2228226) genotypes in 155 CLL patients were detected by direct sequencing. The difference between frequencies of GLI1 Q1100E genotype among CLL patients and controls was statistically significant (p < 0.001). Logistic regression analysis revealed that in comparison with G/G, GLI1 SNP1100 C/C genotype was associated with a significantly increased risk of CLL (OR 3.787, 95 % CI 1.814-7.907, p < 0.001). Compared with the SNP1100 C/G genotype, C/C genotype significantly increased the risk of CLL (OR 3.860, 95 % CI 1.827-8.153, p < 0.001). In addition, combining C/G with G/G, C/C genotype also significantly increased the risk of CLL (OR 3.820, 95 % CI 1.885-7.742, p < 0.001). The comparison between frequencies of C and G allele of GLI1 was also statistically significant (p = 0.004). In the entire cohort, SNP1100 genotypes were found in association with Binet stage (p = 0.045) and trisomy 12 (p = 0.036). By comparing C/C with G allele (C/G+G/G) genotype, there was a significant correlation with trisomy 12 (p = 0.013). This study demonstrated that GLI1 Q1100E polymorphism was closely associated with CLL. C/C genotype contributes to the risk of developing CLL and correlates with trisomy 12. Patients with trisomy 12 are susceptible group of CLL.
    Medical oncology (Northwood, London, England). 12/2014; 31(12):294.
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    ABSTRACT: We fabricated a polarization-dependent terahertz (THz) metamaterial absorber consisted of a metal film, a dielectric spacer and a metal pattern layer. The measured absorptivity for x-polarized wave is about 0.9 at 1.42 THz, and that for y-polarized wave is about 0.87 at 2.15 THz. The full width at half maximum (FWHM) of peaks at 1.42 THz and 2.15 THz are about 0.23 THz and 0.38 THz, respectively. The experimental results are in good agreement with the numerical simulation. In addition, the parameters related to the absorption are presented for deeply understanding the absorption mechanism. Most importantly, these two absorption peaks can be tuned respectively by simply changing the length in x and y directions. Our results suggest potential applications based on metamaterial absorber, such as THz polarization imaging, selective spectral detection, THz sensing and polarization multiplexing.
    Optics Communications 11/2014; 332. · 1.44 Impact Factor
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    ABSTRACT: Abstract Thymic hyperplasia (TH) after chemotherapy is an infrequent phenomenon in adults. This study analyzed the incidence and metabolic activity of TH on (18)F fluorodeoxyglucose ((18)F FDG) positron emission tomography / computed tomography (PET/CT) in this population. By reviewing 471 PET/CT recordings of 211 adults with lymphoma, increased FDG uptake within an enlarged thymus regarded as TH was observed in 27 patients aged 18-53 years. FDG uptake in hyperplasic thymus was mild and diffuse, with a maximum standard uptake value (SUVmax) of 2.6±0.9. Its intensity varied with different occurring times following chemotherapy. In addition, by comparing the recovery of T cell subsets in patients with TH (n=20) and without TH (n=28), no impact of the presence of TH was found on the repopulation of total CD4(+) and CD8(+) T cells within the first year after treatment. These data may be helpful to avoid misinterpretation of increased thymic uptake in adults.
    Leukemia & lymphoma. 11/2014;
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    ABSTRACT: This work reports a one-step synthesis of reduced graphene oxide (rGO) supported platinum-nickel oxide nanoplate arrays (denoted as Pt-NiO/rGO) for nonenzymatic glucose sensing. The prepared Pt-NiO/rGO nanocomposite was characterized by scanning electron microscopy, X-ray energy dispersive spectrometer, and X-ray powder diffraction. The existence of a small quantity of Pt could significantly enhance the catalytic activity of NiO and played an important role in controlling the morphology of Pt-NiO nanoplate arrays. The vertical array structure of Pt-NiO/rGO nanocomposite increased the effective loading of Pt-NiO catalyst on electrode surface to some extent. Therefore, the Pt-NiO/rGO modified glassy carbon electrode (GCE) was successfully used for highly sensitive and selective nonenzymatic glucose detection. The linear range was from 0.008 to 14.5 mM (R2=0.9976, n=41). The sensitivity was 832.95 μA cm−2 mM−1, and the detection limit was 2.67 μM (S/N=3). The good catalytic activity, high sensitivity and stability of the Pt-NiO/rGO/GCE sensor opened up a new kind of hybrid materials in electrochemical detection of glucose.
    J. Mater. Chem. A. 11/2014;
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    ABSTRACT: A simple and convenient approach to prepare three-dimensional (3D) porous carbon with high surface areas of 1880 m2 g-1 as anode materials for lithium ion battery (LIBs) was developed by calcining the Zn4O(BDC)3 (MOF-5, BDC = 1,4-benzenedicarboxylate) at 900 °C for 1 h. The resulted 3D porous carbon released an initial discharge of 2983 mA h g−1 and charge of 1084 mA h g-1 at a current density of 100 mA g−1. The as-prepared porous carbon materials still maintained a high specific capacity of 1015 mA h g-1 after 100 cycles. The 3D porous carbon materials also exhibited superior cyclic stability and reversible capacity. The good performance of porous carbon derived from MOF-5 made it a promising anode material for LIBs or could be used as a good matrix material to construct nanocomposites for LIBs.
    RSC Advances 11/2014; · 3.71 Impact Factor
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    ABSTRACT: Improving the interaction of graphene with terahertz (THz) waves in experiment – through experimental measurement is a challenge for THz detectors, modulators, and other THz photonic components based on graphene. Hybridization of graphene with metamaterials leads to a strong THz response enhancement. Here, we observed maximum enhancement of 33.0% in non-resonant region and 23.8% in resonant region with the hybridization of graphene and metamaterials in experiment. A coupling model as well as numerical calculation has been carried out to fully investigate the influence of this coupling. The results suggest that there exists an exponential relationship between coupling strength and THz response in both resonant and non-resonant region, while the resonant frequency shift shows a linear growth with coupling strength. The bandwidth of the resonance shows exponential increasing with the damping constant. Correspondingly, the numerical calculation shows the similar dependency with the electrical conductivity of the graphene overlayer. This suggests a higher conductivity for stronger coupling. Substrates could also bring the remote phonon scattering, charge transfer, and dielectric effect, which show the influence such as low dielectric constant for high coupling.
    Carbon 11/2014; 78:102–112. · 6.16 Impact Factor
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    ABSTRACT: This letter proposes a surface-energy driven process for economically creating polymer microlens array (MLA) with well controllable curvatures. When a UV-curable prepolymer flows into a cell constructed by multiple holes on a top template and a flat substrate, since the edge pinning of the contact line, an array of curved air/prepolymer interface forms around each microhole of the template. Then a UV-radiation of the bulk prepolymer leads to a solid microlens array. The curvature of the air/prepolymer interface can be controlled by choosing materials with different interface free energy or varying the gap height mechanically.
    ACS Applied Materials & Interfaces 10/2014; · 5.90 Impact Factor
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    ABSTRACT: This paper presents an economical process to create anisotropic microtextures based on periodic parallel stripes of monolayer silica nanoparticles (NPs) patterned by geometrically confined evaporative self-assembly (GCESA). In the GCESA process, a straight meniscus of colloidal dispersion is initially formed in an opened enclosure, which is composed of two parallel plates bounded by a U-shaped spacer sidewall on three sides with an evaporating outlet on the fourth side. Lateral evaporation of the colloidal dispersion leads to periodic "stick-slip" receding of the meniscus (evaporative front), as triggered by "coffee-ring" effect, promoting the assembly of silica NPs into periodic parallel stripes. The morphology of stripes can be well controlled by tailoring process variables such as substrate wettability, NP concentration, temperature, and gap height, etc. Furthermore, arrayed patterns of nanopillar or nanohole are generated on silicon wafer using the as-prepared colloidal stripes as an etching mask or template. Such arrayed patterns can reveal unique anisotropic wetting properties, which have a large contact angle hysteresis viewing from both parallel and perpendicular directions in addition to a large wetting anisotropy.
    ACS Applied Materials & Interfaces 10/2014; · 5.90 Impact Factor
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    ABSTRACT: We previous found the expression level of PTEN was low in the chronic lymphocytic leukemia (CLL) patients. To assess the pathogenic contribution of the low expression of PTEN, we determined PTEN-regulating miRNA interference, PTEN promoter methylation and PTEN gene mutation condition in CLL. One hundred and fifty-four previously untreated CLL patients and 200 cases of healthy controls were sequenced in exons 5-9 of PTEN. None of single nucleotide polymorphism site or mutation was detected in the coding sequences of those exons. Methylation of PTEN promoter was found in one (1.33%) of the 75 patients with CLL, but none of the 25 age-matched control subjects. We found that PTEN was a potential target of miR-26a and miR-214, which had been confirmed following dual-luciferase reporter assays, reverse transcription polymerase chain reaction and Western blotting. High expression of miR-26a was associated with advanced Binet stage (P=0.012), p53 aberrations (P=0.014) and inferior time to first treatment (P=0.038), and high expression of miR-214 was only associated with p53 aberrations (P=0.041). Inhibition of miR-26a or miR-214 could induce more apoptosis in primary cultured CLL cells. These findings support miR-26a and miR-214 down-regulate expression of PTEN in CLL, but not PTEN mutation or promoter methylation.
    Oncotarget 10/2014; · 6.64 Impact Factor
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    ABSTRACT: Metal–organic frameworks (MOFs) have emerged as very fascinating functional materials due to their diversity nature. A nanocomposite consisting of copper nanoparticles dispersed within a carbon matrix (Cu NPs@C) is prepared through a one-pot thermolysis of copper-based metal–organic framework precursors. Cu NPs@C can catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to form a colored product in the presence of H2O2. As a peroxidase mimic, Cu NPs@C not only has the advantages of low cost, high stability, and easy preparation, but also follows Michaelis–Menten behaviors and shows strong affinity to H2O2. As the Cu NPs’ surfaces are free from stabilizing agent, Cu NPs@C exhibited a higher affinity to H2O2 than horseradish peroxidase. On the basis of the inhibitory effect of ascorbic acid (AA) on oxidation of TMB, this system serves as a colorimetric method for the detection of AA, suggesting that the present work would expand the potential applications of MOF-derived nanocomposites in biomedical fields.
    Chemistry 10/2014; · 5.93 Impact Factor
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    ABSTRACT: Bone marrow progenitor cells develop into mature megakaryocytes (MKs) to produce platelets for hemostasis and other physiological functions. However, the molecular mechanisms underlying megakaryopoiesis are not completely defined. We show that cytosolic carboxypeptidase (CCP) 6 deficiency in mice causes enlarged spleens and increased platelet counts with underdeveloped MKs and dysfunctional platelets. The prominent phenotypes of CCP6 deficiency are different from those of CCP1-deficient mice. We found that CCP6 and tubulin tyrosine ligase-like family (TTLL) members TTLL4 and TTLL6 are highly expressed in MKs. We identify Mad2 (mitotic arrest deficient 2) as a novel substrate for CCP6 and not CCP1. Mad2 can be polyglutamylated by TTLL4 and TTLL6 to modulate the maturation of MKs. CCP6 deficiency causes hyperglutamylation of Mad2 to promote activation of Aurora B, leading to suppression of MK maturation. We reveal that Mad2 polyglutamylation plays a critical role in the regulation of megakaryopoiesis.
    The Journal of experimental medicine. 10/2014;
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    ABSTRACT: Objectives: S100 calcium binding protein A12 (S100A12) has been supposed to be a pro-inflammatory factor associated with non-infectious inflammatory diseases. However, whether S100A12 is involved in the inflammatory process of primary biliary cirrhosis (PBC) has not been shown. Methods: The levels of S100A12 mRNA transcripts in peripheral mononuclear blood cells (PBMCs) of 66 Chinese patients with primary biliary cirrhosis (PBC), 62 healthy controls (HC) and 55 chronic hepatitis B (CHB) were measured by qRT-PCR. S100A12 serum concentrations in 34 PBC patients were measured by ELISA. Results: The levels of S100A12 mRNA transcripts in PBMCs of patients with PBC were significantly higher than healthy controls (p < 0.01) and that of patients with CHB (p < 0.01). Importantly, the levels of S100A12 mRNA in PBMCs and S100A12 protein levels in serum were positively correlated with biochemical indicators of bile duct and hepatocyte damage. Conclusion: S100A12 might participate in the damage of biliary epithelial cells and hepatocytes in PBC, and analysis of S100A12 expression could be useful as a surrogate marker for the evaluation of PBC activity.
    Immunological investigations. 10/2014;
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    ABSTRACT: This is a rare instance of acute kidney injury caused by hyperuricemia due to spontaneous tumor lysis syndrome and also the first case of spontaneous tumor lysis syndrome reported in association with myelodysplastic syndrome.
    BMC Nephrology 10/2014; 15(1):164. · 1.64 Impact Factor
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    ABSTRACT: Three kinds of hierarchical porous carbon were successfully fabricated in the absence of any templates by carbonizing kenaf-nickel ion stems complex and subsequently etching nickel-doped carbon composites with hydrochloric acid. The pore size was easily controllable by changing the concentration of nickel ion solution. The unique porous structure of the products resulted in high specific surface area of 1480 m2/g. The creation of mesopores and macropores and construction of hierarchical pores not only improve the accessibility of the active centers, but also provide highways for reaction species, which result in an enhanced performance in a supercapacitor. The resulted porous carbon electrode materials showed improved specific capacitance of 327 F/g at a scan rate of 2 mV/s in 1.0 M H2SO4. Furthermore, the electrode showed a superior super cycle life with 95.6% retention of the initial specific capacitance after 5000 cycles at a current of 1 A/g. This research demonstrated that the hierarchical porous carbon derived from kenaf stems was a good potential material in energy conversion and storage devices.
    RSC Advances 10/2014; · 3.71 Impact Factor
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    ABSTRACT: In this communication, a sensitive electrochemical nitrite sensor was constructed based on poly (diallyldimethylammonium chloride) (PDDA) functionalized reduced graphene oxide (PDDA-rGO). The preparation of PDDA-rGO is quite facile, and the PDDA-rGO exhibits good dispersity and high stability in water, together with good conductivity and positive surface charge. All these factors lead to a greatly enhanced catalysis of PDDA-rGO for the nitrite oxidation compared with that of unmodified rGO or bare glassy carbon electrode. Based on PDDA-rGO, an electrochemical nitrite sensor with low overpotential (0.75 V), wide linear range (0.5 μM–2 mM), low detection limit (0.2 μM), good stability and selectivity was fabricated, which exhibited satisfied recovery for detecting nitrite in drinking water.
    Electrochemistry Communications 10/2014; 47:33–36. · 4.29 Impact Factor
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    ABSTRACT: The Pd/C catalysts with and without a small amount of La2O3 were synthesized by a simple reduction reaction with sodium borohydride in aqueous solution. The structure and morphology of these catalysts were characterized by X-ray diffraction, energy dispersive X-ray spectroscopy and transmission electron microscopy. The electrocatalytic performance of these catalysts for methanol oxidation in alkaline media was investigated using cyclic voltammetry, chronoamperometry and CO stripping experiments. The results show that the Pd–La2O3/C catalyst has a higher catalytic activity than the Pd/C catalyst, but the effect of La2O3 cannot be explained by a bi-functional mechanism. X-Ray photoelectron spectroscopy analyses suggest that the higher content of metallic Pd caused by the addition of La2O3 contributes to the better catalytic activity of Pd–La2O3/C. Based on the good electrocatalytic performance of Pd–La2O3/C, the Pd–La2O3 catalyst supported on chitosan (CS)-functionalized activated carbon nanotubes was prepared, and it exhibited a better catalytic activity. The improvement is attributed to the good dispersion status of metal particles and the further increase of metallic Pd due to the presence of CS.
    International Journal of Hydrogen Energy 09/2014; 39(27):14730–14738. · 3.55 Impact Factor
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    ABSTRACT: Photo-induced electron transfer (PET) is ubiquitous for photosyn-thesis and fluorescent sensor design. However, genetically coded PET sensors are underdeveloped, due to the lack of methods to site-specifically install PET probes on proteins. Here we describe a family of acid and Mn(III) turn-on fluorescent protein (FP) sensors, named iLovU, based on PET and the genetic incorporation of supe-rior PET quenchers in the fluorescent flavoprotein iLov. Using the iLovU PET sensors, we monitored the cytoplasmic acidification process, and achieved Mn(III) fluorescence sensing for the first time. The iLovU sensors should be applicable for studying pH changes in living cells, monitoring biogentic Mn(III) in the envi-ronment, and screening for efficient manganese peroxidase, which is highly desirable for lignin degradation and biomass conversion. Our work establish a platform for many more protein PET sensors, facilitate the de novo design of metalloenzymes harboring redox active residues, and expand our ability to probe protein conforma-tional dynamics.
    Journal of the American Chemical Society 09/2014; · 10.68 Impact Factor
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    ABSTRACT: To examine whether cultivation reduced genetic variation in the important Chinese medicinal plant Rheum tanguticum, the levels and distribution of genetic variation were investigated using ISSR markers. Fifty-eight R. tanguticum individuals from five cultivated populations were studied. Thirteen primers were used and a total of 320 DNA bands were scored. High levels of genetic diversity were detected in cultivated R. tanguticum (PPB = 82.19, H = 0.2498, HB = 0.3231, I = 0.3812) and could be explained by the outcrossing system, as well as long-lived and human-mediated seed exchanges. Analysis of molecular variance (AMOVA) showed that more genetic variation was found within populations (76.1%) than among them (23.9%). This was supported by the coefficient of gene differentiation (Gst = 0.2742) and Bayesian analysis (θ B = 0.1963). The Mantel test revealed no significant correlation between genetic and geographic distances among populations (r = 0.1176, p = 0.3686). UPGMA showed that the five cultivated populations were separated into three clusters, which was in good accordance with the results provided by the Bayesian software STRUCTURE (K = 3). A short domestication history and no artificial selection may be an effective way of maintaining and conserving the gene pools of wild R. tanguticum.
    Genetics and molecular biology. 09/2014; 37(3):540-8.
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    ABSTRACT: A strategy based on carbon nanotubes (CNTs)-containing sizing dispersion has been implemented to fabricate nanocomposite preforms and their hybrid multiscale composites. The state of pristine CNTs and carboxylic acid functionalized CNTs (CNTs–COOH) in sizing dispersion was effectively monitored by on-line measuring electrical conductivity. The effects of different CNTs coating applied onto glass fabric on wettability of nanocomposite fibrous reinforcement with epoxy matrix were evaluated using scanning electron microscopy and capillary experiment. A CNTs-COOH loading of 0.5 wt % gave rise to 97% and 30°C increases in the storage modulus (G′) and glass transition temperature of the resulting hybrid composites, respectively. The enhanced thermomechanical properties of the CNTs hybrid composites are closely related to the stable CNTs sizing dispersion and uniform coating onto fiber reinforcement. The mechanism for reinforcing composites through toughening resin region with CNTs desorbing from primary fiber surface during impregnation has been identified. POLYM. COMPOS., 2014. © 2014 Society of Plastics Engineers
    Polymer Composites 09/2014; · 1.48 Impact Factor
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    ABSTRACT: Cholesterol is an essential component of brain and nerve cells and is essential for maintaining the function of the nervous system. Epidemiological studies showed that patients suffering from anxiety disorders have higher serum cholesterol levels. In this study, we investigated the influence of high cholesterol diet on anxiety-like behavior in elevated plus maze in animal model and explored the relationship between cholesterol and anxiety-like behavior from the aspect of central neurochemical changes.
    Behavioral and brain functions : BBF. 09/2014; 10(1):30.

Publication Stats

3k Citations
1,814.60 Total Impact Points

Institutions

  • 2014
    • Northwest Institute of Plateau Biology
      Hsi-ning-shih, Qinghai Sheng, China
  • 2013–2014
    • China Agricultural University
      • State Key Laboratory for Agrobiotechnology
      Peping, Beijing, China
    • Shenyang Aerospace University
      Feng-t’ien, Liaoning, China
    • Chongqing University of Medical Science
      • Department of Neurology
      Ch’ung-ch’ing-shih, Chongqing Shi, China
    • Shangqiu Normal University
      Zhuji, Henan Sheng, China
    • Fudan University
      • Institute of Biodiversity Science
      Shanghai, Shanghai Shi, China
    • Guilin University of Electronic Technology
      Ling-ch’uan, Guangxi Zhuangzu Zizhiqu, China
    • Xi'an Jiaotong University
      Ch’ang-an, Shaanxi, China
    • Nantong University
      Tungchow, Jiangsu Sheng, China
    • Hefei Institute of Physical Sciences, Chinese Academy of Sciences
      Luchow, Anhui Sheng, China
    • Tianjin University of Technology
      T’ien-ching-shih, Tianjin Shi, China
    • Hangzhou Normal University
      Hang-hsien, Zhejiang Sheng, China
    • Northwest University
      • Institute of Photonics and Photon-Technology
      Ch’ang-an, Shaanxi, China
    • Beijing University of Posts and Telecommunications
      • Department of Communication Engineering
      Peping, Beijing, China
  • 2011–2014
    • Lanzhou University
      • School of Life Science
      Kao-lan-hsien, Gansu Sheng, China
    • Southwest University in Chongqing
      Pehpei, Chongqing Shi, China
    • Chinese Center For Disease Control And Prevention
      Peping, Beijing, China
    • Zhejiang Medical University
      Hang-hsien, Zhejiang Sheng, China
    • Xiangtan University
      • College of Chemistry
      Siangtan, Hunan, China
    • Beijing Normal University
      • College of Resources Science and Technology
      Beijing, Beijing Shi, China
    • Shandong University of Science and Technology
      Tsingtao, Shandong Sheng, China
  • 2010–2014
    • Jiangxi Normal University
      Nan-ch’ang-shih, Jiangxi Sheng, China
    • Tsinghua University
      • Department of Electronic Engineering
      Beijing, Beijing Shi, China
    • Peking University
      • State Key Laboratory of Natural and Biomimetic Drugs
      Beijing, Beijing Shi, China
    • Wenzhou Medical College
      Yung-chia, Zhejiang Sheng, China
    • Ocean University of China
      Tsingtao, Shandong Sheng, China
  • 2008–2014
    • Beijing University of Technology
      Peping, Beijing, China
    • Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
      Hua-yang, Sichuan, China
    • University of Southampton
      • • Faculty of Physical and Applied Sciences
      • • Department of Electronics and Computer Science (ECS)
      Southampton, England, United Kingdom
    • China Agriculture University-East
      Peping, Beijing, China
    • Xinqiao Hospital
      Ch’ung-ch’ing-shih, Chongqing Shi, China
    • Shanghai Institute of Optics and Fine Mechanics, CAS
      Shanghai, Shanghai Shi, China
  • 2007–2014
    • Chongqing Cancer Hospital and Institute
      Ch’ung-ch’ing-shih, Chongqing Shi, China
    • Academy of Military Medical Sciences
      T’ien-ching-shih, Tianjin Shi, China
  • 2006–2014
    • Peking Union Medical College Hospital
      • Department of Rheumatology
      Peping, Beijing, China
  • 2005–2014
    • Chinese Academy of Medical Sciences
      • Institute of Basic Medical Sciences (IBMS)
      Peping, Beijing, China
    • Dalian University of Technology
      • State Key Laboratory of Fine Chemicals
      Lü-ta-shih, Liaoning, China
    • Beijing Cancer Hospital
      Peping, Beijing, China
    • Institute of Genetics and Developmental Biology, CAS
      Peping, Beijing, China
  • 2003–2014
    • Fourth Military Medical University
      • • Department of Medical Genetics and Developmental Biology
      • • Department of Biochemistry and Molecular Biology
      • • State Key Laboratory of Cancer Biology
      Xi’an, Liaoning, China
  • 2002–2014
    • Chinese Academy of Sciences
      • • National Engineering Laboratory for Hydrometallurgical Cleaner Production Technology
      • • Institute of Psychology
      • • Institute of Physics
      • • Institute of Microbiology
      • • Institute of Genetics and Developmental Biology
      Peping, Beijing, China
    • Third Military Medical University
      Ch’ung-ch’ing-shih, Chongqing Shi, China
    • Nanfang Hospital
      Shengcheng, Guangdong, China
  • 2012–2013
    • Shanxi Medical University
      • Department of Physiology
      T’ai-an-shih, Shandong Sheng, China
    • Capital Medical University
      • Department of Pathophysiology
      Peping, Beijing, China
    • Taiyuan University of Technology
      • College of Materials Science and Engineering
      Taiyuan, Shanxi Sheng, China
    • Chongqing University of Technology
      Ch’ung-ch’ing-shih, Chongqing Shi, China
    • Nanyang Technological University
      • School of Biological Sciences
      Singapore, Singapore
    • Huazhong University of Science and Technology
      • School of Public Health
      Wuhan, Hubei, China
    • Tianjin First Central Hospital
      T’ien-ching-shih, Tianjin Shi, China
    • Lanzhou University of Technology
      Kao-lan-hsien, Gansu Sheng, China
  • 2011–2013
    • Renji Hospital
      Shanghai, Shanghai Shi, China
  • 2009–2013
    • Nanjing Medical University
      • Department of Hematology
      Nanjing, Jiangsu Sheng, China
    • Shenyang Pharmaceutical University
      • School of Traditional Chinese Materia Medica
      Feng-t’ien, Liaoning, China
    • Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
      Shanghai, Shanghai Shi, China
    • Beijing Museum of Natural History
      Peping, Beijing, China
    • Henan Provincial People’s Hospital
      Cheng, Henan Sheng, China
    • Southeast University (China)
      Nan-ching-hsü, Jiangxi Sheng, China
  • 2007–2013
    • University of Science and Technology, Beijing
      Peping, Beijing, China
  • 2004–2013
    • Shanghai Jiao Tong University
      • • Shanghai Key Laboratories of Reproductive Medicine
      • • School of Mechanical Engineering
      Shanghai, Shanghai Shi, China
    • Anhui Normal University
      Wu-hu-shih, Anhui Sheng, China
  • 2010–2012
    • Kyoto University
      • Institute for Integrated Cell-Material Sciences (iCeMS)
      Kyoto, Kyoto-fu, Japan
    • Chinese PLA General Hospital (301 Hospital)
      Peping, Beijing, China
  • 2009–2012
    • Ecole Normale Supérieure de Paris
      Lutetia Parisorum, Île-de-France, France
    • Peking University Health Science Center
      Peping, Beijing, China
  • 2007–2012
    • Lanzhou Jiaotong University
      Kao-lan-hsien, Gansu Sheng, China
  • 2005–2012
    • Jilin University
      • • State Key Laboratory of Inorganic Synthesis and Preparative
      • • College of Chemistry
      • • Department of Molecular Biology
      • • State Key Lab of Theoretical and Computational Chemistry
      Jilin, Jilin Sheng, China
  • 2004–2012
    • State Key Laboratory of Medical Genetics of China
      Ch’ang-sha-shih, Hunan, China
  • 2002–2012
    • Northeast Institute of Geography and Agroecology
      • • Institute of Psychology
      • • Institute of Microbiology
      • • Laboratory of Analytical Chemistry for Life Science
      • • Institute of Genetics and Developmental Biology
      • • Institute of Physics
      • • State Key Laboratory of Electroanalytical Chemistry
      Beijing, Beijing Shi, China
  • 2009–2011
    • Wuhan University
      Wu-han-shih, Hubei, China
  • 2008–2011
    • Changhai Hospital, Shanghai
      Shanghai, Shanghai Shi, China
  • 2005–2010
    • Tohoku University
      • • Department of Applied Bioorganic Chemistry
      • • School of Engineering
      Sendai-shi, Miyagi-ken, Japan
  • 2008–2009
    • Second Military Medical University, Shanghai
      Shanghai, Shanghai Shi, China
  • 2001–2008
    • Technical Institute of Physics and Chemistry
      Peping, Beijing, China
  • 2004–2005
    • Beijing Jiaotong University
      • Institute of Optoelectronics Technology
      Beijing, Beijing Shi, China