K Suzuki

Nihon University, Edo, Tōkyō, Japan

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Publications (7)10.76 Total impact

  • N Kobayashi · K Suzuki · H Shibuya · T Sato · I Aoki · Y Nagashima
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    ABSTRACT: An 8-year-old, male, mongrel dog developed severe cough and anorexia and died within 3 months. Autopsy revealed an invasive grayish-white mass in the right kidney and multiple nodules in the lungs, thoracic wall, and spleen. Histologically, the renal mass and the other nodules were mainly composed of papillotubular structures lined by oval-to-polygonal pleomorphic cells. The cells were reactive with DBA, PNA, and UEA-1 lectins and positive for vimentin but negative for CD10 and high molecular weight cytokeratin. Because of its histological, histochemical, and immunohistochemical similarities with human collecting duct carcinoma (CDC), a diagnosis of renal collecting duct carcinoma with pulmonary, thoracic, and splenic metastases was established. To our knowledge, this is the first case report of CDC in animals.
    Veterinary Pathology 08/2008; 45(4):489-94. DOI:10.1354/vp.45-4-489 · 1.87 Impact Factor
  • K Suzuki · H Koie · T Matsumoto · R Asano
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    ABSTRACT: Several animal studies have demonstrated the beneficial effects of hypertonic saline (HSS) on cerebral blood flow, intracranial pressure and brain water content. This study aimed to investigate, using magnetic resonance imaging, whether a small volume of HSS is superior to dextran in vasodilatation of cerebral vessels and reduction of cerebrospinal fluids in dogs. HSS induced a significant expansion of the cross-section of the superior sagittal sinus in the axial transverse section of the pituitary and a decrease in cerebrospinal fluid area in the axial transverse section of the epencephalon more than dextran 40 did (p<0.001, respectively). However, the relative plasma volume in the dog which received dextran 40 was significantly higher after t=30min than in the HSS group (p<0.001). Therefore, it is suggested that HSS might be superior to colloid solutions in improving cerebral circulation, whereas dextran 40 is superior to HSS in enhancing systemic circulation in dogs.
    Research in Veterinary Science 06/2008; 84(3):465-70. DOI:10.1016/j.rvsc.2007.05.016 · 1.41 Impact Factor
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    ABSTRACT: The development of an oscillator controller for a bipedal robot with antagonistic pairs of pneumatic actuators is reported. Periodic motions of the legs switch between the swinging and supporting stages based on the phase of the oscillators. The oscillators receive touch sensor signals at the end of the legs as feedback when the leg touches the ground and compose a steady limit cycle of the total periodic dynamics of bipedal locomotion. The effectiveness and performance of the proposed controller were evaluated with numerical simulations and experiments with the hardware.
    Journal of Mechanical Science and Technology 05/2007; 21(6):976-980. DOI:10.1007/BF03027080 · 0.84 Impact Factor
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    ABSTRACT: The angiopoietin (Ang) family of proteins are central to the regulation of angiogenesis. The purposes of this study were to determine cDNA sequences of canine Ang-1 and Ang-2 and investigate their expressions in normal tissues and spontaneous tumours. The cDNA sequences of canine Ang-1 and Ang-2 were 1,494 and 1,488 bp, and the deduced amino acid sequences were 497 and 495 residues, respectively. The cDNA sequences of canine Ang-1 and Ang-2 showed high homology with those of the other mammalian species. Canine Ang-1 and Ang-2 mRNA were detectable in all 22 normal tissues and spontaneous tumours. Higher mRNA expression level of canine Ang-2 was demonstrated in mammary simple carcinomas, haemangiosarcoma and hepatocellular carcinoma in comparison with normal tissues.
    Research in Veterinary Science 11/2006; 81(2):280-6. DOI:10.1016/j.rvsc.2005.12.004 · 1.41 Impact Factor
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    K Suzuki · K Nakatani · H Shibuya · T Sato
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    ABSTRACT: A 10-year-old, female, mongrel showed hemorrhage from vulva. By magnetic resonance image (MRI) and endoscopic examination, a multipapillary mass with a grape-like appearance was found around the urethral opening. Histologically, the mass consisted of variable-sized round-, spindle-to-polygonal-shaped tumor cells including many multinuclear cells. Mitotic figures were also frequently observed. In some areas, that tumor cells were loosely arranged, with intercellular myxoid components. Immunohistochemically, these tumor cells were strongly positive for vimentin and focally positive for desmin but negative for myoglobin. Thus, the case was diagnosed as a relatively poorly differentiated botryoid rhabdomyosarcoma by the macroscopic, histopathologic, and immunohistochemical identification. This is the first report of botryoid rhabdomyosarcoma developing in the vagina of a dog.
    Veterinary Pathology 04/2006; 43(2):186-8. DOI:10.1354/vp.43-2-186 · 1.87 Impact Factor
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    S Saito · K Suzuki · H Shibuya · T Yamaguchi · T Sato
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    ABSTRACT: We report a tumor that developed at the root of the tail in a male, 2-year-old Shih Tzu dog. Histologically, the tumor consisted of basaloid epithelial cells, with shadow cells and neoplastic melanocyte proliferation. Immunohistochemically, epithelial components were positive for keratin/cytokeratin but basaloid cells were negative. Mononuclear or multinuclear melanocytes were positive for vimentin, S-100 protein, and HMB-45. In conclusion, this dog was diagnosed with canine melanocytic matricoma on the basis of the similarity of the histologic and immunohistochemical features in humans, and it may be the first case in an animal.
    Veterinary Pathology 08/2005; 42(4):499-502. DOI:10.1354/vp.42-4-499 · 1.87 Impact Factor
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    T Sato · H Koie · H Shibuya · K Suzuki
    The Veterinary record 01/2005; 155(24):780-1. DOI:10.1136/vr.155.24.780 · 1.49 Impact Factor