K Suzuki

Nihon University, Edo, Tōkyō, Japan

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Publications (2)3.02 Total impact

  • K Suzuki, H Koie, T Matsumoto, R Asano
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    ABSTRACT: Several animal studies have demonstrated the beneficial effects of hypertonic saline (HSS) on cerebral blood flow, intracranial pressure and brain water content. This study aimed to investigate, using magnetic resonance imaging, whether a small volume of HSS is superior to dextran in vasodilatation of cerebral vessels and reduction of cerebrospinal fluids in dogs. HSS induced a significant expansion of the cross-section of the superior sagittal sinus in the axial transverse section of the pituitary and a decrease in cerebrospinal fluid area in the axial transverse section of the epencephalon more than dextran 40 did (p<0.001, respectively). However, the relative plasma volume in the dog which received dextran 40 was significantly higher after t=30min than in the HSS group (p<0.001). Therefore, it is suggested that HSS might be superior to colloid solutions in improving cerebral circulation, whereas dextran 40 is superior to HSS in enhancing systemic circulation in dogs.
    Research in Veterinary Science 06/2008; 84(3):465-70. DOI:10.1016/j.rvsc.2007.05.016 · 1.51 Impact Factor
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    ABSTRACT: The angiopoietin (Ang) family of proteins are central to the regulation of angiogenesis. The purposes of this study were to determine cDNA sequences of canine Ang-1 and Ang-2 and investigate their expressions in normal tissues and spontaneous tumours. The cDNA sequences of canine Ang-1 and Ang-2 were 1,494 and 1,488 bp, and the deduced amino acid sequences were 497 and 495 residues, respectively. The cDNA sequences of canine Ang-1 and Ang-2 showed high homology with those of the other mammalian species. Canine Ang-1 and Ang-2 mRNA were detectable in all 22 normal tissues and spontaneous tumours. Higher mRNA expression level of canine Ang-2 was demonstrated in mammary simple carcinomas, haemangiosarcoma and hepatocellular carcinoma in comparison with normal tissues.
    Research in Veterinary Science 11/2006; 81(2):280-6. DOI:10.1016/j.rvsc.2005.12.004 · 1.51 Impact Factor

Publication Stats

3 Citations
3.02 Total Impact Points

Institutions

  • 2006–2008
    • Nihon University
      • Department of Veterinary Medicine
      Edo, Tōkyō, Japan