Publications (2)12.03 Total impact
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Article: Acetoacetanilides as masked isocyanates: facile and efficient synthesis of unsymmetrically substituted ureas.
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ABSTRACT: A general and practical method for the preparation of unsymmetrically substituted ureas has been developed. By the reactions of acetoacetanilides with various amines including primary/secondary amines, a series of substituted aryl ureas were achieved in high yields. Acetoacetanilide substrates can be considered as masked reagents that liberate reactive isocyanates in situ.Organic Letters 10/2010; 12(19):4220-3. · 5.86 Impact Factor -
Article: Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation-ring-opening of cyclopropane-intramolecular cyclization.
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ABSTRACT: An efficient synthesis of fully substituted pyridin-2(1H)-ones was developed via three-component one-pot reactions of readily available 1-acetyl-1-carbamoyl cyclopropanes, malononitrile and cyclic secondary amines.Chemical Communications 07/2009; · 6.17 Impact Factor