Jian Liu

Publications (2)9.72 Total impact

• Source

  Available from: PubMed Central

  Article: Enzootic angiostrongyliasis in Shenzhen, China.

  Ren-Li Zhang, Mu-Xin Chen, Shi-Tong Gao, Yi-Jie Geng, Da-Na Huang, Jian-Ping Liu, Yuan-Liang Wu, Xing-Quan Zhu
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  ABSTRACT: To the Editor: Angiostrongylus cantonensis is a zoonotic parasite that causes eosinophilic meningitis in humans after they ingest infective larvae in freshwater and terrestrial snails and slugs, paratenic hosts (such as freshwater fish, shrimps, frogs, and crabs), or contaminated vegetables. With the increase of income and living standards, and the pursuit of exotic and delicate foods, populations around the world have seen angiostrongyliasis become an important foodborne parasitic zoonosis (1-9).
  Emerging Infectious Diseases 01/2009; 14(12):1955-6. · 6.79 Impact Factor
• Article: Intercellular adhesion molecule-1 gene K469E polymorphism and ischemic stroke: a case-control study in a Chinese population.

  Xiao Xia Li, Jian Ping Liu, Jin Quan Cheng, Sheng Hong Han, Yi Jie Geng, Sheng Wei, Shi Tong Gao, Da Na Huang, Shao Fa Nie
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  ABSTRACT: Intercellular adhesion molecule-1 (ICAM-1) was involved in the pathogenetic mechanisms responsible for ischemic stroke (IS). Population-based sample have revealed gene-gender interaction in blood pressure which is major risk for IS. We sought to evaluate whether ICAM-1 K469E polymorphism was involved in the causation of IS and whether it was different between female and male. A 1:1 case-control study was conducted. The K469E polymorphism of ICAM-1 gene were analyzed by polymerase chain reaction (PCR) and restriction enzyme analysis in Chinese patients with IS (n = 309) and elderly subjects without IS (n = 309). ICAM-1 K469E polymorphism was significantly associated with IS. Interestingly, a further analysis stratified by sex found that there was significance between 469E genotypes and IS in female, but not in male. Multiple regression analysis revealed that ICAM-1 K469E polymorphism was still significantly associated with IS, compared with ICAM-1 KK genotype in all population (OR = 1.60, P = 0.030). Stratified by sex, EE combined EK was contributory factor to IS in female (OR = 3.03, P = 0.004), but not in male. After adjustment for confounding factors, the interaction between female and ICAM-1 EK/EE genotypes was found (OR = 3.54, P = 0.001). It is suggested that the ICAM-1 469E allele may be important in the pathogenesis of ischemic stroke, especially in female but not in male.
  Molecular Biology Reports 10/2008; 36(6):1565-71. · 2.93 Impact Factor