Jin Young Kim

Eulji University, Daiden, Daejeon, South Korea

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Publications (410)1131.18 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: In mammals, circadian rhythms are generated at least in part by a cell-autonomous transcriptional feedback loop in which the three PERIOD (PER) and two CRYPTOCHROME (CRY) proteins inhibit the activity of the dimeric transcription factor CLOCK-BMAL1, thereby repressing their own expression. Upon nuclear entry, the PER and CRY proteins form a large protein complex (PER complex) that carries out circadian negative feedback by means of at least two basic functions: (1) it brings together multiple effector proteins that repress transcription and (2) it delivers these repressive effectors directly to CLOCK-BMAL1 bound to E-box sequences of circadian target genes. At present, the composition, mechanisms of action, and dynamics of PER complexes in circadian clock negative feedback are incompletely understood. Here, we describe several experimental approaches to the study of PER complexes obtained from mammalian tissues. We focus on the isolation of nuclei from mouse tissues, the extraction of PER complexes from the isolated nuclei, characterization of native PER complexes by gel filtration and blue native polyacrylamide gel electrophoresis, preparative immunoaffinity purification of PER complexes for mass spectrometric identification of constituent proteins, and chromatin immunoprecipitation to monitor the recruitment of PER complex proteins to CLOCK-BMAL1 at E-box sites of clock-regulated genes. © 2015 Elsevier Inc. All rights reserved.
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    ABSTRACT: Polysulfone-based membranes with pyridine (PY) side chains, crosslinked by imidazole (IM) groups, are synthesised, doped with phosphoric acid (PA) and characterised in the hydrogen/air fuel cell at 160 °C. It is shown that the bisphenol A (BPA) group of Udel P-3500 (Solvay) acts as a breaking point, and Radel R-5000 NT (Solvay)-based membranes, in which BPA is substituted for biphenyl, show superior stability. Undoped membranes show thermal stability of up to 330 °C (3% weight loss, 10 °C/min, nitrogen). PA-doped membranes: The weight gain during acid doping is limited by the high crosslink density, and independent of the doping temperature. By varying the ratio of pyridine to imidazole units from 2:1 to 9:1, the PA uptake can be controlled between 200 and 500 wt%, respectively. The Young modulus increases with the crosslinking density from 12 to 129 MPa. Proton conductivity of the PY/IM 2:1 membrane at 160 °C reaches 59 mS/cm. In the fuel cell, the PY/IM 2:1 membrane achieved a potential of ca. 500 mV at 0.2 A/cm2. After 430 h (330 h at 0.2 A/cm2, then 0.4 A/cm2), the cell failed, and postmortem analysis suggested severe chemical degradation. Washing the membrane with ammonia solution before doping increased the stability further.
    Solid State Ionics 07/2015; 275. DOI:10.1016/j.ssi.2015.03.026 · 2.11 Impact Factor
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    Jang Hyun Lee, Jin Young Kim, Chul Han Kim
    Yonsei medical journal 07/2015; 56(4):1167-1169. DOI:10.3349/ymj.2015.56.4.1167 · 1.26 Impact Factor
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    ABSTRACT: Exfoliated graphitic carbon nitride nanosheets (g-C3N4-NS) were applied for the first time to the preparation of an electrocatalyst for the oxygen reduction reaction (ORR). A less dense structure with increased surface area was observed for g-C3N4-NS compared to bulk g-C3N4 from detailed analyses including TEM, STEM, AFM with depth profiling, XRD, and UV-Vis spectroscopy. The pyrolysis of the prepared g-C3N4-NS with Co and carbon under inert environment provided enhanced accessibility to the N functionalities required for efficient interaction of Co and C with N for the formation of Co-N-C networks and produced hollow and interconnected Co-N-C-NS structure responsible for high durability. The Co-N-C-NS electrocatalyst exhibited superior catalytic activity and durability and further displayed fast and selective four electron transfer kinetics for the ORR, as evidenced by various electrochemical experiments. The hollow, interconnected structure of Co-N-C-NS with increased pyridinic and graphitic N species was proposed to play a key role in facilitating the desired ORR reaction.
    Nanoscale 05/2015; 7(23). DOI:10.1039/C5NR01584G · 6.74 Impact Factor
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    ABSTRACT: Optical-resolution photoacoustic microscopy (OR-PAM) is an imaging tool to provide in vivo optically sensitive images in biomedical research. To achieve a small size, fast imaging speed, wide scan range, and high signal-to-noise ratios (SNRs) in a water environment, we introduce a polydimethylsiloxane (PDMS)-based 2-axis scanner for a flexible and waterproof structure. The design, theoretical background, fabrication process and performance of the scanner are explained in details. The designed and fabricated scanner has dimensions of 15 × 15 × 15 mm along the X, Y and Z axes, respectively. The characteristics of the scanner are tested under DC and AC conditions. By pairing with electromagnetic forces, the maximum scanning angles in air and water are 18° and 13° along the X and Y axes, respectively. The measured resonance frequencies in air and water are 60 and 45 Hz along the X axis and 45 and 30 Hz along the Y axis, respectively. Finally, OR-PAM with high SNRs is demonstrated using the fabricated scanner, and the PA images of micro-patterned samples and microvasculatures of a mouse ear are successfully obtained with high-resolution and wide-field of view. OR-PAM equipped with the 2-axis PDMS based waterproof scanner has lateral and axial resolutions of 3.6 μm and 26 μm, respectively. This compact OR-PAM system could potentially and widely be used in preclinical and clinical applications.
    Sensors 05/2015; 15(5):9815-26. DOI:10.3390/s150509815 · 2.05 Impact Factor
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    Hyun Seung Song, Jin Young Kim
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    ABSTRACT: [Purpose] This study was to assessed the efficacy of a complex exercise program for the elderly, with respect to the effects on walking ability during direction change and on falls efficacy. [Subjects] In total, 40 subjects were selected for this study and assigned randomly to either a complex exercise (n = 20) or a general exercise (n = 20) group. [Methods] The complex exercise consisted of resistance and aerobic exercises. The exercise program was conducted three times a week for eight weeks. We assessed outcome measures of the four square step test, the figure-of-8 walk test, and the falls efficacy scale. [Results] After the intervention, the four step square test, figure-of-8 walk test, and falls efficacy scale values increased significantly in both the complex exercise program and general exercise groups. The complex exercise group showed a more significant improvement than the general exercise group in the figure-of-8 walk test step and falls efficacy scale scores. [Conclusion] Complex exercise improved walking ability during direction change and falls efficacy in elderly individuals.
    Journal of Physical Therapy Science 05/2015; 27(5):1365-1367. DOI:10.1589/jpts.27.1365 · 0.20 Impact Factor
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    ABSTRACT: We report a case of agranulocytosis caused by ethambutol in a 79-year-old man with pulmonary tuberculosis. He was referred for fever and skin rash developed on 21th day after antituberculosis drugs (isoniazid, rifampicin, ethambutol, and pyrazinamide) intake. Complete blood count at the time of diagnosis of pulmonary tuberculosis was normal. On the seventh admission day, agranulocytosis was developed with absolute neutrophil count of 70/µL. We discontinued all antituberculosis drugs, and then treated with granulocyte colony-stimulating factor. Three days later, the number of white blood cell returned to normal. We administered isoniazid, pyrazinamide, and ethambutol in order with an interval. However, fever and skin rash developed again when adding ethambutol, so we discontinued ethambutol. After these symptoms disappeared, we added rifampicin and ethambutol in order with an interval. However after administering ethambutol, neutropenia developed, so we discontinued ethambutol again. He was cured with isoniazid, rifampicin, and pyrazinamide for 9 months.
    Tuberculosis and Respiratory Diseases 04/2015; 78(2):125-127. DOI:10.4046/trd.2015.78.2.125
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    03/2015; 13(3). DOI:10.14801/jkiit.2015.13.3.53
  • 03/2015; 2(1):15-22. DOI:10.12989/bme.2015.2.1.015
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    ABSTRACT: Currently, most sulfonated poly(arylene ether sulfone) (s-PAES) polymers are synthesized using a solvent mixture consisting of toluene and dimethylacetamide (DMAc) by two successive reactions, namely azeotropic water removal, followed by nucleophilic substitution. In this study, a novel method for the synthesis of s-PAES polymers has been developed, where alcohols such as methanol, ethanol, or 2-propanol are used along with DMAc as the co-solvent in the place of toluene that is used in the conventional synthesis of s-PAES. Moreover, the synthesis method used in this study involves only one step, namely the polymerization at 160 °C and does not require the azeotropic water distillation step at 140 °C. The new synthesis method was found to yield s-PAES polymers with a higher molecular weight in a shorter reaction time compared to the conventional polymerization method. Further, membrane electrode assemblies (MEA) were fabricated using the synthesized s-PAES polymer membranes, in order to evaluate the performance of the membranes in polymer electrolyte membrane fuel cells (PEMFCs). The results indicate that the s-PAES membranes synthesized using the method proposed in this study have a great potential for use as PEMFC membranes.
    Solid State Ionics 03/2015; 275. DOI:10.1016/j.ssi.2015.03.001 · 2.11 Impact Factor
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    ABSTRACT: The purpose of this study is to evaluate the clinical usefulness of modulated arc (mARC) treatment techniques. The mARC treatment plans of the non-small cell lung cancer (NSCLC) patients were performed in order to verify the clinical usefulness of mARC. A pre study was conducted to find the most competent plan condition of mARC treatment and the usefulness of mARC treatment plan was evaluated by comparing it with the other Arc treatment plans such as Tomotherapy and RapidArc. In the case of mARC, the optimal condition for the mARC plan was determined by comparing the dosimetric performance of the mARC plans with the use of various parameters. The various parameters includes the photon energies (6 MV, 10 MV), optimization point angle (6{\deg}-10{\deg} intervals), and total segment number (36-59 segment). The best dosimetric performance of mARC was observed at 10 MV photon energy and the point angle 6 degree, and 59 segments. The each treatment plans of three different techniques were compared with the following parameters: conformity index (CI), homogeneity index (HI), target coverage, dose in the OARs, monitor units (MU), beam on time and the normal tissue complication probability (NTCP). As a result, all three different treatment techniques show the similar target coverage. The mARC results the lowest V20 and MU per fraction compared with both RapidArc and Tomotherapy plan. The mARC plan reduces the beam on time as well. Therefore, the results of this study provided a satisfactory result which mARC technique is considered as a useful clinical technique for radiation treatment.
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    ABSTRACT: [Purpose] The objective of this study was to determine the effect of transcranial direct current stimulation (tDCS) during task-related training (TRT) on the gait ability of patients with chronic stroke. [Subjects and Methods] The participants were 24 patients who were diagnosed with hemiplegia due to stroke. Three groups were created: subjects who performed TRT for general exercise therapy (TRT), subjects who received sham tDCS during TRT for general exercise therapy (TST), and subjects who received tDCS during TRT for general exercise therapy (TT). [Results] The stance phase symmetry profile, the swing phase symmetry profile, and gait velocity all decreased significantly in the TT group compared with the TRT group. However, there was no significant difference in the step length symmetry profile among the groups. [Conclusion] A application of tDCS, that affects the excitatory regulation in the cortical motor area, is an effective rehabilitation method for gait improvement.
    Journal of Physical Therapy Science 03/2015; 27(3):623-5. DOI:10.1589/jpts.27.623 · 0.20 Impact Factor
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    ABSTRACT: Vorinostat has been shown to overcome resistance to gefitinib. We performed a phase I/II study combining gefitinib with vorinostat in previously treated non-small cell lung cancer (NSCLC). A 3 + 3 dose-escalation design was used to determine maximum tolerated dose (MTD) and recommended phase II dose (RP2D). Three dose levels were tested: 250 mg/day gefitinib on days 1-28 and 200, 300 or 400 mg/day vorinostat on days 1-7, and 15-21 out of every 28 days. The primary endpoint was median progression-free survival (PFS). Fifty-two patients were enrolled and treated (43 in phase II). The median age was 59 years, 28 patients were male, 44 had adenocarcinoma, 29 had never smoked, and 36 had undergone one prior treatment. Twenty-two patients exhibited sensitive EGFR mutations. Planned dose escalation was completed without reaching the MTD. The RP2D was 250 mg gefitinib and 400 mg vorinostat. In 43 assessable patients in phase II, the median PFS was 3.2 months; the overall survival (OS) was 19.0 months. There were 16 partial responses and six cases of stable disease. In EGFR-mutant NSCLC, response rate was 77 %, median PFS was 9.1 months, and median OS was 24.1 months. The most common adverse events were anorexia and diarrhea. Treatment with 250 mg gefitinib daily with biweekly 400 mg/day vorinostat was feasible and well tolerated. In an unselected patient population, this combination dose did not improve PFS. However, this combination showed a potential for improving efficacy of gefitinib in EGFR-mutant NSCLC (NCT01027676).
    Cancer Chemotherapy and Pharmacology 03/2015; 75(3). DOI:10.1007/s00280-014-2664-9 · 2.57 Impact Factor
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    ABSTRACT: Endocrine therapies that inhibit oestrogen receptor (ER)-α signaling are the most common and effective treatment for ER-α-positive breast cancer. The present study aimed to elucidate the mechanisms by which down-regulation of serum- and glucocorticoid-inducible protein kinase-1 (SGK1) expression confers tamoxifen resistance in breast cancer. SGK1 expression and the cytotoxic effects of combinatorial 4-hydroxy-tamoxifen (4-OHT) treatment with SGK1 overexpression were investigated by immunoblotting, bromodeoxyuridine incorporation, and soft agar assay. We showed that PIN1 down-regulates SGK1 expression through interaction with and ubiquitination of SGK1. PIN1 silencing in MCF7 cells increased SGK1 expression. In tamoxifen-resistant human breast cancer, immunohistochemical staining analysis showed an inverse correlation between SGK1 expression and severity of tamoxifen resistance. Importantly, 4-OHT in combination with overexpression of SGK1 increased cleavage of poly-(ADP-ribose) polymerase and DNA fragmentation to inhibit clonogenic growth of tamoxifen-resistant MCF7 (TAMR-MCF7) cells. We suggest that PIN1-mediated SGK1 ubiquitination is a major regulator of tamoxifen-resistant breast cancer cell growth and survival. Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.
    Anticancer research 02/2015; 35(2):785-94. · 1.87 Impact Factor
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    ABSTRACT: Human detection is a challenging problem in video processing, which is applied in many fields: robot control, surveillance system, traffic tracking etc. Recently, there have been many publications involving this problem. However, most of methods still focus on pedestrian detection. In this paper, based on the poselet techniques, we introduce a new method to detect human in video under various environments. By combining poselet and gradient local auto-correlation classifier, we propose an efficient technique in human detection and reduce false detection. Also, focused on edge-based robust principal component analysis, a new foreground extraction method is developed to handle the ambiguous environment such as: leaf motion, illumination etc. By applying the proposed method, the small motion artifacts can be rejected. Experimental results show that our method has the high accuracy in various environments.
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    ABSTRACT: Optical-resolution photoacoustic microscopy (OR-PAM) is a novel label-free microscopic imaging tool to provide in vivo optical absorbing contrasts. Specially, it is crucial to equip a real-time imaging capability without sacrificing high signal-to-noise ratios (SNRs) for identifying and tracking specific diseases in OR-PAM. Herein we demonstrate a 2-axis water-proofing MEMS scanner made of flexible PDMS. This flexible scanner results in a wide scanning range (9 × 4 mm(2) in a transverse plane) and a fast imaging speed (5 B-scan images per second). Further, the MEMS scanner is fabricated in a compact footprint with a size of 15 × 15 × 15 mm(3). More importantly, the scanning ability in water makes the MEMS scanner possible to confocally and simultaneously reflect both ultrasound and laser, and consequently we can maintain high SNRs. The lateral and axial resolutions of the OR-PAM system are 3.6 and 27.7 μm, respectively. We have successfully monitored the flow of carbon particles in vitro with a volumetric display frame rate of 0.14 Hz. Finally, we have successfully obtained in vivo PA images of microvasculatures in a mouse ear. It is expected that our compact and fast OR-PAM system can be significantly useful in both preclinical and clinical applications.
    Scientific Reports 01/2015; 5:7932. DOI:10.1038/srep07932 · 5.58 Impact Factor
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    ABSTRACT: [Purpose] This study aimed to determine differences in gait abilities by comparing class-based task-oriented circuit training (CTCT) and individual-based task-oriented circuit training (ITCT). [Subjects and Methods] The subjects were 30 patients who were diagnosed with hemiplegia due to stroke more than six months previously. They were divided into Group I (n=10), which received conventional physiotherapy, Group II (n=10), which received conventional physiotherapy and ITCT, and Group III (n=10), which received conventional physiotherapy and CTCT. To determine the qualitative aspect of gait ability, a GAITRite (CIR Systems Inc., Sparta NJ, USA) was employed, while a two-minute walking test (2MWT) was conducted to determine the quantitative aspect. [Results] The gait ability showed significant differences in velocity, cadence, and 2MWT between groups in the significance test. As a result, the Bonferroni post test showed that gait velocity was significantly different between Groups I and II and between Groups I and III, while cadence showed a significant difference between Groups I and III. In the 2MWT, Groups I and II and Groups I and III also showed significant differences. [Conclusion] Both the individual and class applications task-oriented circuit training were effective for improving gait ability. This result indicates that CTCT can improve the physical ability of stroke patients as much as ITCT.
    Journal of Physical Therapy Science 01/2015; 27(1):187-9. DOI:10.1589/jpts.27.187 · 0.20 Impact Factor
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    ABSTRACT: [Purpose] This study aimed to determine the difference in self-satisfaction in patients by comparing class-based task-oriented circuit training (CTCT) and individual-based task-oriented circuit training (ITCT). [Subjects and Methods] The subjects were 30 patients who had been diagnosed with hemiplegia due to stroke more than six month previously. They were divided into Group I (n=9) for conventional therapy, Group II (n=10) for conventional therapy and ITCT, and Group III (n=11) for conventional therapy and CTCT. In order to determine self-satisfaction as a psychological factor in patients, we used a self-esteem scale (SES), motivation of rehabilitation scale (MR), and relationship change (RCS) scale. [Results] SES, MR, and RCS, which were measured to determine self satisfaction as a psychological factor were significantly different between groups. The Bonferroni post hoc test revealed a significant difference between Group I and Group III in SES, a significant difference between Group I and Group III and Group II and Group III in MR, and a significant difference between Group I and Group III were found. [Conclusion] Based on the above results, task-oriented circuit training was more effective when performed in a class than when performed individually in terms of self-satisfaction. Based on this result, we determined that CTCT has as positive an effect on the mental aspects of stroke patients compared with ITCT.
    Journal of Physical Therapy Science 01/2015; 27(1):127-9. DOI:10.1589/jpts.27.127 · 0.20 Impact Factor
  • Garam Kim, Jin Young Kim, Hong Seok Choi
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    ABSTRACT: Phosphorylation of proteins on serine or threonine residues preceding proline is a pivotal signaling mechanism regulating cell proliferation. The recent identification and characterization of the enzyme peptidyl-prolyl cis/trans isomerase never in mitosis A (NIMA)-interacting 1 (PIN1) has led to the discovery of a new mechanism regulating phosphorylation in cell signaling. PIN1 specifically binds phosphorylated serine or threonine residues immediately preceding proline (pSer/Thr-Pro) and then regulates protein functions, including catalytic activity, phosphorylation status, protein interactions, subcellular location, and protein stability, by promoting cis/trans isomerization of the peptide bond. Recent results have indicated that such conformational changes following phosphorylation represent a novel signaling mechanism in the regulation of many cellular functions. Understanding this mechanism also provides new insight into the pathogenesis and treatment of human hepatocellular carcinoma. A better understanding of the role of PIN1 in the pathogenesis of hepatocellular carcinoma may lead to the identification of molecular targets for prevention and therapeutic intervention.
    Biological & Pharmaceutical Bulletin 01/2015; 38(7):975-9. DOI:10.1248/bpb.b15-00245 · 1.78 Impact Factor
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    ABSTRACT: Abstract Hydrogen production via steam reforming of a simulated biogas was achieved in a temperature range of 500-800 °C over a plate-type Ni-Al catalyst. To enhance the catalytic activity of the Ni-Al catalyst, a pretreatment process involving pre-oxidation with sequential reduction was employed prior to the reforming reactions. The activated Ni-Al catalyst exhibited increased methane conversion depending on the pre-oxidation temperature. Studies using X-ray diffraction and scanning electron microscopy suggested that the catalyst surface was restructured upon pretreatment, ultimately improving the catalytic activity. To increase its catalytic stability, CeO2 was employed additionally as a structural promoter to prevent both Ni sintering and carbon deposition. The durability of the CeO2-coated Ni-Al catalyst was improved significantly, particularly upon addition of ≥2.8 wt% of CeO2, with ca. 75 % of CH4 conversions being achieved without deactivation over 100 h at 700 °C. The influence of the pre-oxidation temperature, reforming temperature, and steam/CH4 ratio on reforming over a CeO2-Ni-Al catalyst was also elucidated. In addition, the potential roles of CeO2 in the enhancement of activity and stability were discussed. Graphical Abstract
    Catalysis Letters 01/2015; DOI:10.1007/s10562-015-1532-5 · 2.29 Impact Factor

Publication Stats

4k Citations
1,131.18 Total Impact Points

Institutions

  • 2015
    • Eulji University
      • Department of Internal Medicine
      Daiden, Daejeon, South Korea
  • 2014–2015
    • Soonchunhyang University
      • College of Medicine
      Onyang, Chungcheongnam-do, South Korea
    • Gyeongsang National University
      • Department of Otolaryngology
      Shinshū, Gyeongsangnam-do, South Korea
    • Seoul National University Hospital
      Sŏul, Seoul, South Korea
    • Pukyong National University
      Tsau-liang-hai, Busan, South Korea
    • Ulsan National Institute of Science and Technology
      Urusan, Ulsan, South Korea
    • Case Western Reserve University School of Medicine
      • Department of Urology
      Cleveland, Ohio, United States
  • 2013–2015
    • Harvard Medical School
      • Department of Neurobiology
      Boston, Massachusetts, United States
    • NASA
      Вашингтон, West Virginia, United States
    • Temple University
      • Department of Anatomy and Cell Biology
      Philadelphia, Pennsylvania, United States
    • Inje University Paik Hospital
      Sŏul, Seoul, South Korea
    • Korea University
      Sŏul, Seoul, South Korea
    • University of Toronto
      • Department of Electrical and Computer Engineering
      Toronto, Ontario, Canada
    • Korea Aerospace University
      • School of Aerospace and Mechanical Engineering
      Kōyō, Gyeonggi Province, South Korea
  • 2010–2015
    • Pohang University of Science and Technology
      • • Department of Mechanical Engineering
      • • Department of Materials Science and Engineering
      Geijitsu, Gyeongsangbuk-do, South Korea
    • National Fisheries Research and Development Institution
      Sŏul, Seoul, South Korea
    • Robert Wood Johnson University Hospital
      New Brunswick, New Jersey, United States
    • Icahn School of Medicine at Mount Sinai
      Borough of Manhattan, New York, United States
  • 2009–2015
    • National Cancer Center Korea
      • Lung Cancer Branch
      Kōyō, Gyeonggi-do, South Korea
    • Chosun University
      • • Department of Medicine
      • • College of Pharmacy
      • • Department of Pharmacy
      Gwangju, Gwangju, South Korea
    • Hallym University Medical Center
      • Department of Ophthalmology
      Sŏul, Seoul, South Korea
    • Robert Wood, Johnson University Hospital At Hamilton
      New Jersey, United States
  • 2002–2015
    • Chonnam National University
      • Department of Electrical, Electronic Communication and Computer Engineering
      Gwangju, Gwangju, South Korea
  • 2000–2015
    • Korea Institute of Science and Technology
      • Fuel Cell Research Center
      Sŏul, Seoul, South Korea
    • Inha University Hospital
      Sinhyeon, South Gyeongsang, South Korea
  • 2012–2014
    • Dongguk University
      Sŏul, Seoul, South Korea
    • University of Incheon
      • Department of Physics
      Sŏul, Seoul, South Korea
    • Hanyang University
      • College of Engineering
      Ansan, Gyeonggi, South Korea
    • University of Massachusetts Amherst
      • School of Computer Science
      Amherst Center, Massachusetts, United States
  • 2010–2014
    • Keimyung University
      • Dongsan Medical Center
      Sŏul, Seoul, South Korea
  • 2005–2014
    • Ewha Womans University
      • • Department of Chemistry Nano Science
      • • Department of Preventive Medicine
      • • Division of Nursing Science
      Sŏul, Seoul, South Korea
    • Nagaoka University of Technology
      • Department of Chemistry
      Нагаока, Niigata, Japan
  • 2004–2014
    • Yonsei University
      • • Department of Otorhinolaryngology
      • • Department of Materials Science and Engineering
      • • Department of Internal Medicine
      • • Institute of Gastroenterology
      Sŏul, Seoul, South Korea
    • Yonsei University Hospital
      • Department of Internal Medicine
      Sŏul, Seoul, South Korea
  • 2003–2014
    • Pusan National University
      • • Department of Nanomaterials Engineering
      • • Department of Physics
      Tsau-liang-hai, Busan, South Korea
  • 2001–2014
    • Kwangwoon University
      • • Department Electronics Convergence Engineering
      • • Department of Electronic Material Engineering
      • • Department of Radio Sciences & Engineering
      • • Department of Electrical Engineering
      Sŏul, Seoul, South Korea
  • 2000–2014
    • Korea Basic Science Institute KBSI
      Sŏul, Seoul, South Korea
  • 1999–2014
    • Kunsan National University
      • Department of Physics
      Gunzan, Jeollabuk-do, South Korea
  • 1991–2014
    • Seoul National University
      • • Department of Ophthalmology
      • • Department of Chemistry
      • • Department of Biological Sciences
      • • College of Medicine
      • • College of Pharmacy
      • • Department of Materials Science and Engineering
      • • Department of Electrical and Computer Engineering
      Sŏul, Seoul, South Korea
  • 2011–2013
    • Hyundai Heavy Industries
      Urusan, Ulsan, South Korea
    • University of Texas at Austin
      • Department of Civil, Architectural & Environmental Engineering
      Austin, Texas, United States
  • 2010–2013
    • Kwandong University
      • College of Medicine
      Gangneung, Gangwon, South Korea
  • 2011–2012
    • Kyung Hee University
      Sŏul, Seoul, South Korea
  • 2008–2012
    • Jeju National University
      • Faculty of Biotechnology
      Tse-tsiu, Jeju, South Korea
    • Sogang University
      • Department of Computer Science and Engineering
      Sŏul, Seoul, South Korea
  • 2004–2012
    • Sungkyunkwan University
      Sŏul, Seoul, South Korea
  • 2010–2011
    • Chungnam National University
      • College of Pharmacy
      Sŏngnam, Gyeonggi Province, South Korea
  • 2009–2011
    • National Institutes of Health
      • Laboratory of Cancer Prevention
      Maryland, United States
  • 2008–2011
    • National Renewable Energy Laboratory
      گلدن، کلرادو, Colorado, United States
    • Massachusetts Institute of Technology
      • Department of Materials Science and Engineering
      Cambridge, MA, United States
  • 2008–2009
    • The Scripps Research Institute
      • Department of Chemical Physiology
      La Jolla, California, United States
    • Chung-Ang University
      • • College of Pharmacy
      • • College of Medicine
      Sŏul, Seoul, South Korea
  • 2003–2009
    • Catholic University of Korea
      • • Department of Internal Medicine
      • • College of Medicine
      • • Department of Microbiology
      Sŏul, Seoul, South Korea
  • 2007
    • University of California, Santa Barbara
      • Center for Polymers and Organic Solids
      Santa Barbara, CA, United States
  • 2005–2007
    • Yanbian University
      Yang-chi-t'eng, Jilin Sheng, China
  • 2006
    • Asan Medical Center
      • Department of Oncology
      Sŏul, Seoul, South Korea
  • 2005–2006
    • University of California, Davis
      • Department of Chemistry
      Davis, California, United States
  • 2003–2006
    • Samsung Advanced Institute of Technology
      Usan-ri, Gyeonggi Province, South Korea
  • 2002–2003
    • Catholic University of Daegu
      • Department of Radiology
      Kayō, Gyeongsangbuk-do, South Korea
  • 2001–2003
    • Korea Advanced Institute of Science and Technology
      • Department of Materials Science and Engineering
      Sŏul, Seoul, South Korea
  • 1998–2000
    • Princeton University
      • Department of Electrical Engineering
      Princeton, New Jersey, United States
    • Hyundai Engineering Co., Ltd.
      Sŏul, Seoul, South Korea
  • 1995–1998
    • Dongseo University
      Tsau-liang-hai, Busan, South Korea