Publications (5)2.39 Total impact
-
Article: [Determination of arsenic, mercury and selenium in Gynostemma pentaphyllum and rhizospheric soil samples collected from different regions by hydride generation atomic fluorescence spectrometry].
[show abstract] [hide abstract]
ABSTRACT: The contents of arsenic (As), mercury (Hg) and selenium (Se) in Gynostemma pentaphyllum and rhizospheric soil samples collected from seven provinces were determined, through the optimization of the hydride generation atomic fluorescence spectrometry working conditions. The results show that: the contents of As, Hg and Se in Gynostemma pentaphyllum from seven provinces revealed large differences, but compared with the limits of the two kinds of heavy metal element: As and Hg set by the Green Trade Standards of Importing & Exporting Medicinal Plants & Preparations (As < or = 2.0 mg x kg(-1), Hg < or = 0.2 mg kg(-1)), the As and Hg contents in Gynostemma pentaphyllum samples are both lower than them. The Se content in Gynostemma pentaphyllum samples and in rhizospheric soil samples revealed significant correlation, and as a result, the Gynostemma pentaphyllum from the Fu Xi area Enshi in Hu Bei province had obviously higher Se content than others in the 6 provinces. From this study, a preliminary conclusion can be drawn that Se in Gynostemma pentaphyllum is mainly from the soil, moreover, the As and Hg show the difference from Se, possibly they are still affected by the dry and wet deposition of atmospheric aerosols.Guang pu xue yu guang pu fen xi = Guang pu 03/2012; 32(3):813-6. · 0.84 Impact Factor -
Article: Effects of benzo[a]pyrene on autonomic nervous system of coke oven workers.
[show abstract] [hide abstract]
ABSTRACT: Objectives are to investigate the effects of benzo[a]pyrene (B[a]P) on the autonomic nervous system of coke oven workers. One hundred eighty-four coke oven workers were divided into 3 groups according to their working sites (coke oven bottom group, coke oven side group and coke oven top group), and 93 referents were recruited. B[a]P monitored by air sampling pumps as well as urinary 1-hydroxypyrene (1-OH-Py) was determined by high performance liquid chromatograph with a fluorescence detector (HPLC-FD). The autonomic nervous system (ANS) function was determined by 4 tests: Valsalva Manoeuvre heart rate variation (HR-V), variation of heart rate when breathing deeply (HR-DB), variation of heart rate when instantly standing up (HR-IS, including RR30:15 and RRmax:min) and variation of blood pressure when instantly standing up (BP-IS). The B[a]P mean concentrations in coke oven bottom, coke oven side and coke oven top were 19, 185 and 1,623 ng/m(3), respectively. The levels of urinary 1-OH-Py were markedly higher in the 3 exposed groups than that in the referent group (p<0.01). No significant difference was found in each group between smokers and non-smokers (p>0.05). Compared with referents, HR-V decreased significantly in coke oven workers (p<0.01), representing modulation of parasympathetic nervous function. However, no statistical differences were found in HR-DB, RR30:15, RRmax:min and BP-IS between the exposed groups and the control group (p>0.05). HR-V decreased with the increment of 1-OH-Py (p<0.05), and results of multiple linear stepwise regression demonstrated that external exposure level and duration of education entered the HR-V model; age was a significant factor of HR-DB and RRmax:min, but no variable was involved in RR30:15 and BP-IS regression. Benzo[a]pyrene affects the autonomic nervous function of coke oven workers mainly by down-regulating the parasympathetic nervous function.Journal of Occupational Health 05/2008; 50(4):308-16. · 1.55 Impact Factor -
Article: [Lipid peroxidation injury and endoplasmic reticulum stress in Al-induced apoptosis].
[show abstract] [hide abstract]
ABSTRACT: To study the role of lipid peroxidation injury and endoplasmic reticulum stress in Al-induced apoptosis. Neurons from 0-3 day rats were cultured and treated with different concentrations of AlCl3.6H2O. Morphologic changes of neurons and endoplasmic reticulum were observed under fluorescent and transmission electron microscope; activities of superoxide dismutase (SOD), malondialdehyde (MDA) and ATP enzymes were detected. Typical morphologic changes in neurons apoptosis and endoplasmic reticulum were found under fluorescent and transmission electron microscope; SOD enzyme viability and ATP enzyme viability were significantly increased in the low-dosage group, but reduced in mid and high-dosage group (P < 0.01), whereas MDA levels decreased in the low-dosage group, but increased in mid and high-dosage group (P < 0.01). Aluminum may induce neurons apoptosis, and lipid peroxidation injury in endoplasmic reticulum plays an important role in the apoptosis progression.Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 03/2008; 26(3):143-6. -
Article: [Characteristic of the neurobehavioral functional changes in coke oven workers].
[show abstract] [hide abstract]
ABSTRACT: To explore the effect of polycyclic aromatic hydrocarbons on the neurobehavioral function of coke oven workers. 200 healthy adult male coke oven workers were selected from a coke plant of a state-owned steel enterprise in Taiyuan City. 88 controls occupationally unexposed to polycyclic aromatic hydrocarbons (PAHs) were selected from the same enterprise. All the subjects participated in this investigation voluntarily in their consent. Concentration of B(a)P in the working environment was monitored by High Performance Liquid Chromatography (HPLC). Urine samples were sampled immediately after working shifts. The level of urinary 1-hydroxypyrene was determined by HPLC. General information of workers correlated with the investigation was collected in a questionnaire according to the same criteria by well-trained investigators. Neurobehavioral core test battery (NCTB) recommended WHO was performed on coke oven workers and controls to test the neurobehavioral changes and the mood state. the concentration of B(a)P at oven bottom,oven side and oven top were 0.0195 microg/m3, 0.186 microg/m3 and 1.624 microg/m3 respectively, that at oven side and oven top being higher than the one stipulated by the occupational hygiene criterion. Urinary 1-hydroxypyrene was significantly different between the exposure group (3.42 +/- 0.98 micromol/mol creatinine) and control group (2.75 +/- 1.09 micromol/mol creatinine). No significant differences were found between exposure group and control group of age, working years, smoking, drinking and unhealthy food consumption; however, compared to the controls, the scores of total digital span, the forward digital span, and right dotting in the coke oven workers were lower, but that of total dotting was higher, with a statistical significance. According to urinary 1-hydroxypyrene concentration, all the subjects were divided into three groups. (<3.10 micromol/mol creatinine, 3.10 micromol/mol creatinine, >3.87 micromol/mol creatinine). Significant differences of the total digital span, the forward digital span, backward digital span, digit symbol and Benton visual retentions existed in different urinary 1-hydroxypyrene concentration groups and showed a dose-response tendency. Results of multiple stepwise regression analysis and correlation analysis showed that the level of urinary 1-hydroxypyrene affected memory and perception of coke oven workers and negative correlations between the level of urinary 1-hydroxypyrene and changes in neurobehavioral function were found. PAHs mainly causes decrease of memory and perception in coke oven workers.Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 02/2008; 42(1):25-9. -
Article: [Change of neurocytes in acute intoxicated encephalopathy induced by 1, 2-dichloroethane after intervention with antagonists].
[show abstract] [hide abstract]
ABSTRACT: To study the role of N-methyl-D-aspartate receptor and Ca(2+) in acute intoxicated encephalopathy induced by 1, 2-dichloroethane (1, 2-DCE) in vitro. Neurocytes of new born rats were cultured in vitro, which were administered with different doses of 1, 2-DCE, and NMDAR and Ca(2+) antagonists including Ketamine and Nimodiping respectively. The cell morphologic structures were observed under light microscope, and its proliferation was detected by Cell Counting Kit-VIII. 1, 2-DCE could damage the normal morphological structure of neurocytes: the cell body swelled and broke down, the karyon slurred or disappeared, the axone became shorten and thick, connection of neurocytes was reduced, the cell membrane was half-baked, injury of neurocytes became severer with the increase of the dose of 1, 2-DCE. There was no statistical difference in the proliferation of neurocytes between every 1, 2-DCE groups (P > 0.05), but there was significantly statistical difference between 1, 2-DCE groups, the control group, and the retarder groups (P < 0.01). 1, 2-DCE can damage the normal morphological structure of neurocytes, and the damage will become severer with the increase of the dose of 1, 2-DCE. However, the cell morphologic structures and proliferation of antagonist groups are much better than those in the 1, 2-DCE groups.Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 01/2008; 25(12):726-9.
Top co-authors
Top Journals
Institutions
-
2012
-
Shaanxi Normal University
Xi’an, Guangdong Sheng, China
-
-
2008
-
shanxi medical university
- Department of Occupational Health
Taiyuan, Shanxi Sheng, China
-
