ABSTRACT: The aim of the prospective study was to evaluate the long-term effect of the lens epithelial cells (LEC) removal by means of the lens capsule mechanical polishing on the development of the anterior capsule opacification (ACO) and posterior capsule opacification (PCO).
The study group consisted of 28 patients, average age 57 years (27-87 years), who underwent the cataract surgery of both eyes. Out of the 28 patients, the follow up examination after two or more years attended 23 of them. For the irrigation and aspiration after the phacoemulsification, the bimanual (newly also called biaxial) irrigationlaspiration from two service, 1 mm wide, opposite (at the 3 and 9 o'clock positions) incisions was used. In each patient, the lens capsule of one eye was mechanically polished in the maximal mydriasis (at least 5 minutes) with a specially constructed 5 openings aspiration cannula designated especially for the LEC aspiration in the equator area. The anterior capsule was cleaned by means of the standard one opening aspiration cannula. In the other eye of the same patient, the LEC of the anterior capsule were left intact. There was implanted the same type of the intraocular lens in both eyes. The examination after more than two years after the surgery consisted of biomicroscopic examination, taking the photograph of the intraocular lens and the lens capsule in retro illumination, and examining of the anterior segment by means of the Scheimpflug camera (Pentacam) with measuring the density of the anterior and posterior lens capsule. The Wilcoxon pair test was used for the statistical evaluation.
Using the Pentacam system objective densitometry, there was found statistically significant lower density of the anterior lens capsule in eyes with peroperative mechanical polishing of the lens capsule including the equator and the anterior capsule. Among the values of the density of the posterior capsule, there were found no statistically significant differences, although in 43% of patients, in the eye with the polished capsule, there were visually less dense opacities of the posterior capsule.
According to the obtained results it may be stated that the mechanical polishing of the lens capsule, including the equator and the anterior capsule, causes significantly lower degree of opacities of the anterior capsule (ACO), but has not statistically significant influence to the development of the PCO.
Ceská a slovenská oftalmologie: casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 02/2010; 66(1):21-5.
ABSTRACT: Ischemic edema of the retina develops after CRAO and a regressive phase follows usually without any possibility of objectification. The aim of the study is to determine dynamics of edematous changes in the central retina using the OCT (Optical Coherence Tomography).
Department of Ophthalmology, Regional Hospital in Pardubice, Czech Republic, E.U.
During the period between June 2004 and January 2005, ten patients with the diagnosis of CRAO were examined by means of Stratus OCT3 (Zeiss). A protocol designed for analysis of the thickness and volume of the macula (Fast Macular Thickness Map) was used for the evaluation. Obtained readings were compared with the healthy eye. Examinations were performed on the 1st up to the 5th day after the CRAO onset and 2, 5, and 10 weeks thereafter.
The average volume of the macula (Average Total Macula Volume) of the affected eye was (mean +/- SD; mm3): at the day of diagnosis (the initial examination) 9.196 +/- 1.376 (range, 10.315-7.301), the 2nd week 7.313 +/- 1.209 (range, 9.441-5.854), the 5th week 5.970 +/- 0.688 (range, 7.401-4.971), and the 10th week 5.091 +/- 0.558 (range, 5.768-3.989). The average volume of the most swollen macular quadrate was (mean +/- SD; mm3): at the day of diagnosis (the initial examination) 0.695 +/- 0.319 (range, 1.526-0.359), the 2nd week 0.607 +/- 0.206 (range, 1.118-0.416), the 5th week 0.520 +/- 0.220 (range, 1.070-0.334), and the 10th week 0.409 +/- 0.195 (range 0.948-0.282). In some patients, the onset of macular atrophy was found 5 weeks after the CRAO. No edema in the macular area was confirmed in any patient 10 weeks after the CRAO.
On the average, we proved the regression phase of the retinal edema 5 weeks after the CRAO appearance. The OCT examination appears to be a suitable method for the determination of the dynamics of the edematous changes in the macular area after the CRAO.
Ceská a slovenská oftalmologie: casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 06/2009; 65(3):75-8.
ABSTRACT: The authors describe a quite unique case of metastatic affection of the iridial tissue in a 69-year-old female patient treated from 2000 for primary lung cancer. Before assessment of the ophthalmological diagnosis the patient reported pain and redness of the right eye persisting for two weeks. On examination extensive proliferating tissue in the area of the temporal part of the right iris was found and secondarily a painful glaucoma. Treatment with regard to the case-history and general condition of the patient involved enucleation of the affected eye. Histological examination confirmed subsequently the presence of a metastasis of a small cell spindle-shaped lung cancer into the iris with dissemination in the anterior chamber and corneal endothelium.
Ceská a slovenská oftalmologie: casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 10/2002; 58(5):315-8.