I W Hanham

Publications (2)4.53 Total impact

• Article: Serum galactosyl transferase levels in patients with advanced cancer.

  I D Capel, H M Dorrell, D C Williams, I W Hanham, H N Levitt
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  ABSTRACT: Serum galactosyl transferase was significantly higher in patients with various types of cancer than in age-matched controls. The highest serum enzyme levels were observed in the breast and respiratory cancer, followed by ovarian and gastrointestinal tumours; whereas the enzyme activity in prostatic cancer patients was not significantly higher than in the control subjects. In the cancer patients the serum levels of this enzyme were not significantly higher in the presence of metastases. In terminally ill patients, the serum enzyme activity decreased proportionately in accordance with the progression of their disease.
  Oncology 02/1982; 39(4):193-6. · 2.27 Impact Factor
• Article: The serum levels of some trace and bulk elements in cancer patients.

  I D Capel, M H Pinnock, D C Williams, I W Hanham
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  ABSTRACT: The levels of copper, zinc, calcium, manganese and magnesium have been monitored in the sera of patients suffering from various types of cancer. Only serum copper appeared to be of any diagnostic significance, its levels being above the normal reported range in the breast cancer, leukaemia and Hodgkin's lymphoma patients. In the case of breast cancer, serum copper is progressively elevated according to the stage of the disease. Serum calcium levels were also significantly lower in patients with tumours of the breast, gastrointestinal tract and cervix. The results suggest that serum copper levels could be of prognostic significance in breast cancer patients receiving radiotherapy.
  Oncology 02/1982; 39(1):38-41. · 2.27 Impact Factor